(1) Hopital Habib Thameur, Tunis, TUNISIE","contentIntroduction":"Heart failure (HF) is a common presentation in the emergency department. Searching for risk factors is a challenging step in the emergency physicians . The purpose of our study was to search for prognosis values of ratio PaO2 /FiO2 in patients admitted in the emergency department for acute heart failure.","contentPatientsMethods":"Prospective monocentric observational study, conducted between November 2021 and January 2022. We included patients aged 18, we established diagnosis of HF on clinical grounds. We performed blood gases at admission. The primary endpoint was in hospital mortality.","contentResultats":"We included 100 patients. Average age: 73±11 years and sex ratio M/F=51/49. The most common comorbidities were hypertension n (%) :81(82), diabetes 46 (47), coronary artery disease 47(47); 68.4% had an Left Ventricular Ejection Fraction(LVEF) more than 40%, with an average pro-BNP of 9,440 pg/ml; 37.4% of patients had permanent atrial fibrillation. 24% returned in < 30 days with an average of readmissions/year of 1.75(±0.96). Seventy-two patients (76%) required ventilatory support, 5% required the use of invasive mechanical ventilation. Mortality rate 12% . There was no significant difference in terms of comorbidity between the deceased and surviving group. However, dead patients had a higher SOFA score (4.5 vs 2; p=0.001), a lower LVEF (43% vs 25%; p=0.18). D-dimers and CRP were higher in the death group, with a median of 3636 vs 1385 (p = 0.001) and 98 vs 56 (p = 0.08), the ratio PaO2/FiO2 in admission was 195 in dead group vs 298 in survivors group (p=0.01) .The ratio PaO2/FiO2 was as an independent mortality factor (OR=0.99, CI [0.98; 1], p=0.05). Using the ROC curve, the best cut-off for the PaO2/FiO2 ratio was 160. A PaO2/FiO2 ratio ≤160 was predictive of mortality with an AUC of 0.74, a sensitivity of 86% and a specificity of 76%.","contentDiscussion":"","contentConclusion":"Pao2/Fio2 ≤160 is an independent factor of death with patients admitted in the emergency department with acute heart failure.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1194","session":"FLASH COM - La personne âgée en réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHABARA Racha"},{"id":99384,"num":"A34733RG","reference":"FC-050","title":"Care Prognosis and Outcomes in elderly patients admitted to the intensive care unit","formatedAuthors":"Mouna JERBI (1), Rezk GHORBEL (1), Achraf REKIK (1), Kais BEN JEDDOU (1), Emna GHARBI (1), Boutheina BEN AMAR (1), Olfa CHAKROUN (1), Noureddine REKIK (1)
(1) centre Hospitalo-universitaire Habib Bourguiba sfax, Sfax, TUNISIE","contentIntroduction":"Describe the medical histories, demographic characteristics and analyze the standardized geriatric assessment elderly patients admitted to emergency department intensive care unit (EDUCI) . Determine the pathologies found in these patients as well as the therapeutic and outcomes.","contentPatientsMethods":"This is a prospective descriptive study carried out at the EDUCI of the Habib Bourguiba university hospital, during a period of four months. We included all people aged 65 and older admitted to our intensive care unit.\n We observed their therapeutic management as well as their demographic and evolutionary characteristics. We also calculated the ADL score for all patients and follow-up of their evolution on leaving the emergency room.","contentResultats":"Our study involved 262 patients during the enrollment period. The average age was 77±8 years with a sex ratio of 1.1 . From pathological medical history was noted in most patients (82 %) dominated by hypertension and diabetes mellitus. The majority of patients (73.7 %) are polymedicated.\n The history of hospitalization was found in 42 % of cases. Data anamnestics have shown the presence of cognitive disorders and Alzheimer's disease in 21 % and 6,9 % of cases, respectively. The ADL score showed a loss of autonomy for 38.8% of the population. The reasons of hospitalizations were mainly for medical reasons and, to a lesser title, traumatic and visceral while the deterioration of the general state was involved in 5% cases. (11%) were put on mechanical ventilation . (9%) patients who required a blood transfusion . The average length of hospital stay was 3.4 ±4 days. The evolution was favorable in the majority of cases (75%). Among home leavers (41%), a quarter sustained moderate or severe sequelae. These sequelae were essentially a deficit neurological, resuscitation neuromyopathy and/or pressure sores. The evolution has been fatal in 16,8 % of cases, in the EDICU. The main causes of death were cerebral suffering (8 %), septic shock and hypoxemia.","contentDiscussion":"","contentConclusion":"The admission of geriatric patients to the ICU is increasing. Frailty assessment may play an important role in the clinical evaluation of such individuals for triage, but should not be considered a priori as an exclusion criterion for admission. Physicians are aware of the difficulties faced with such patients and the need to promote short admission pathways.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1194","session":"FLASH COM - La personne âgée en réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHORBEL Rezk"},{"id":99385,"num":"A34439LB","reference":"FC-051","title":"French translation and validation of the Healthy Aging Brain Care-Monitor, Hybrid Version (HABC-M-HV): a new tool for remote post-intensive care syndrome screening.","formatedAuthors":"Laurine BOUGARD (1), Charlotte BEAUDART (1), Camille COLSON (1), Geoffrey HORLAIT (2), Stephen BORNHEIM (3), Olivier BRUYERE (1,3), Benoit MISSET (1), Anne-Françoise ROUSSEAU (1)
(1) CHU Liège, Liège, BELGIQUE ; (2) CHU UCL Namur, Namur, BELGIQUE ; (3) University of Liège, Liège, BELGIQUE","contentIntroduction":"Patients surviving a stay in an intensive care unit (ICU) may experience new or worsening disorders that have been labeled as “post-intensive care Syndrome” (PICS). PICS includes physical weakness, mental disorders and neurocognitive impairments that can affect the patient’s quality of life. Authors of the Healthy Aging Brain Care Monitor have developed a hybrid version (HABC-M-HV) suited to the daily needs of their post-ICU follow-up clinic. This is a 30-item questionnaire with 4 subscales for cognitive, functional, psychological and quality of life assessment. The hybrid version of the HABC-M questionnaire (HABC-M-HV) has not yet been validated in its English version. Using rigorous methodologies, the objectives of this cross-sectional observational study were to translate the HABC-M-HV questionnaire into French (HABC-M-HV-F, figure 1) and to evaluate the main measurement properties of this new version.","contentPatientsMethods":"The questionnaire was translated following a five-stage validated method for the translation and cross-cultural adaptation of questionnaires. A convenience sample of ICU survivors was recruited in our follow-up clinic to validate the questionnaire. The HABC-M-HV-F was administered by phone. The measurement performances of the questionnaire were tested using internal consistency, test-retest reliability, standard error of measurement (SEM) and smallest detectable change (SDC) calculation, floor and ceiling effect measurement and construct validity.","contentResultats":"A total of 51 patients with 14/51 (27.5%) women were recruited between February and September 2021. Their median age was 63 [55-71] years. The internal consistency was very good (Cronbach’s alpha coefficient 0.79). The intra- and inter-examinator reliabilities were excellent (Intraclass Coefficient Correlation = 0.99 and 0.97, respectively). Total scores of the HABC-M-HV-F were very similar between test and retest with the same examinator, respectively 9 [3.75-15.5] and 8.5 [3.75- 16.25], as well as with two examinators, respectively 12 [6-24.5] and 12 [4.-23.5]. The SEM was 0.62 and the SDC was 1.72. No floor nor ceiling effects were observed. The convergent validity was almost entirely confirmed with 71.4% of our hypothesis confirmed.","contentDiscussion":"","contentConclusion":"The HABC-M-HV-F has been shown to be a valid and reliable tool for standardized PICS screening and follow-up among French-speaking ICU survivors. A remote administration by phone is feasible, making it an advantageous alternative in the growing context of telemedicine.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1194","session":"FLASH COM - La personne âgée en réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUGARD Laurine"},{"id":99386,"num":"A34477GP","reference":"FC-052","title":"Ceftolozane/Tazobactam use for the treatment of bacterial infections in France: Focus on patients with abnormal renal functions","formatedAuthors":"Raymond RUIMY (1), Brune AKRICH (2), Xavier BOURGE (2), David BOUTOILLE (3), Isabelle BRASSAC (2), Bernard CASTAN (4), Raphaèle LORIEAU-THIBAULT (2), Carole MACKOSSO (2), Linsay MONTEIRO TAVARES (5), Joy MOOTIEN (6), Fabrice RUIZ (5), Jean-François TIMSIT (7)
(1) CHU Nice, Nice, FRANCE ; (2) MSD France, Puteaux, FRANCE ; (3) CHU Nantes, Nantes, FRANCE ; (4) CH Périgueux, Périgueux, FRANCE ; (5) ClinSearch, Malakoff, FRANCE ; (6) CHU Mulhouse, Mulhouse, FRANCE ; (7) AP-HP Bichat, Paris, FRANCE","contentIntroduction":"The Conduct study was initiated following a request from the French Health Authorities, to describe the use of Ceftolozane/Tazobactam (C/T) in current clinical practice.","contentPatientsMethods":"This was an observational, prospective, multicenter, French study. Any patient having received at least one dose of C/T was eligible to participate and followed-up upon inclusion until stop of C/T. This analysis aims to examine C/T outcomes relative to renal functions, in patients with pneumonia, or treated for complicated intra-abdominal (cIAI) or urinary tract infections (cUTI) and pyelonephritis (other indications). Current recommended daily C/T doses are 6g/3g for pneumonia treatment (indication approved in August 2019), and 3g/1.5g for the other indications, with decreased daily doses recommended in patients with renal impairment. Normal renal functions were defined as creatinine clearance (CLCR) between 50-150 mL/min, augmented renal clearance (ARC) was defined as CLCR >150 mL/min, and renal impairment (RI) as CLCR <50 mL/min.","contentResultats":"Between October 2018 and December 2019, 260 patients were enrolled and data on renal functions were available for 240. Of these, 133 (55.4%) presented with pneumonia (of whom, 30.8% [N=41/133] included after the approved indication), and 50 (20.8%) received C/T for the three other approved indications (the remaining 57 received C/T for another indication - data not shown). Baseline demographic and clinical characteristics are presented in Table 1.\n Among patients treated for pneumonia and included after the indication was approved, all RI patients received a dose adaptation (less than 6g/3g). On the other hand, 3/5 (60%) of ARC patients and 10/29 (34.5%) of patients with normal renal functions received doses lower than 6g/3g.\n For the other indications, the majority of ARC and normal renal function patients received the standard dose (57.1% [N=4/7] and 71% [22/31], respectively); 42.8% of ARC patients and 22.6% with normal renal function received higher doses (between 4g/2g and 6g/3g). Among RI patients, dose adaptation was not strictly followed (8/12 received 3g/1.5g, and one patient received 4.5g/2.25g). \n In both groups, the most commonly reported reasons for treatment termination were complete or partial cure (100%, 93.1%, 85.7%, for ARC, normal renal functions, and RI pneumonia patients respectively, and 57.1%, 71%, 66.6%, for the same subgroups in patients with other indications).","contentDiscussion":"","contentConclusion":"These results suggest that C/T dose adaptation is followed by most clinicians, and provides important cure rates among all renal function groups.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"RUIMY Raymond"},{"id":99387,"num":"A34653VJ","reference":"FC-053","title":"Does the cefepime plasma concentration at steady-state in critical ill patients frequently exceed the maximum target assumed to be neurotoxic ?","formatedAuthors":"Vanessa JEAN-MICHEL (1), Corentin HOMEY (1), Thomas CAULIER (1), Pierre-Yves DELANNOY (1), Nicolas BOUSSEKEY (1), Hugues GEORGES (1)
(1) CH TOURCOING, Tourcoing, FRANCE","contentIntroduction":"Cefepime (CEF) is one of antimicrobials commonly prescribed for nosocomial infections in intensive care unit (ICU). Neurotoxicity of cefepime can occur for plasma concentration > 35 mg/L, when administered by continuous infusion [1,2].\n We aimed to assess the risk factors of plasma CEF concentration at steady state above 35 mg/L. We also determined the relationship between neurotoxicity, CEF concentration and general co-morbidities.","contentPatientsMethods":"We performed a retrospective study of adult ICU patients treated with CEF for at least 48 hours between January 2019 and September 2021.","contentResultats":"Fifty-seven patients were included. Twenty-one patients had a renal clearance < 60 mL/min/1.73m2 before CEF initiation. The mean starting daily dose of CEF was 5.4 (1.3) g. The mean time to first CEF monitoring was 2.9 (1.7) days and the incidence of CEF concentration above 35 mg/L was 46/57 (80.7 %) patients. \n Factors independently associated with CEF concentration above 35 mg/L were age upper to 65 years old [OR = 4.1 (95% CI 1.1 – 62.1), p = 0.04] and initial daily delivery of six g of CEF [OR = 2.7 (95% CI 1.2 – 68.9); p = 0.03]. \n Presumed CEF neurotoxicity was 12/57 (21.1%) patients. Mean CEF concentration was higher for patients who developed neurotoxicity: 85 (31.2) mg/L vs 50.9 (23.4) mg/L; p = 0.001. No patient with neurotoxicity had a CEF concentration of 35 mg/L or less.\n The mean treatment duration was 5.4 (2.6) days. The mean time to develop neurotoxicity related to CEF was 4.8 (1.8) days. Seventeen patients were not neurologically assessable due to deep sedation. The mean time from CEF change to neurological improvement was 2.8 (1.6) days. \n CEF concentration above 40 mg/L (p = 0.01) was more frequently associated with neurotoxicity in univariate analysis but did not appear to be an independent factor. The only independent factor for presumed CEF neurotoxicity was estimated glomerular filtration rate below 60 mL/min/1.73m2 at initiation of treatment [OR = 8.6 (95% CI 1.4 – 51.9); p = 0.02].","contentDiscussion":"","contentConclusion":"CEF concentration above 35 mg/L is frequent and therefore should be systematically investigated to prevent neurotoxicity.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Guilhaumou R, Benaboud S, Bennis Y, Dahyot-Fizelier C, Dailly E, Gandia P, et al. Optimization of the treatment with beta-lactam antibiotics in critically ill patients. Crit Care Lond Engl. 2019;23:104.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Huwyler T, Lenggenhager L, Abbas M, Ing Lorenzini K, Hughes S, Huttner B, et al. Cefepime plasma concentrations and clinical toxicity: a retrospective cohort study. Clin Microbiol Infect. 2017 Jul;23(7):454-9","presentateur":"JEAN-MICHEL Vanessa"},{"id":99388,"num":"A34693OV","reference":"FC-054","title":"Population pharmacokinetics of fluconazole and dosing simulations in critically ill patients","formatedAuthors":"Olivia VASSAL (1), Elodie MATUSIK (2,3), Tristan FERRY (4,5), Aurelien MILLET (6), Julien BOHE (1), Jerome GUITTON (6), Arnaud FRIGGERI (1,5), Sylvain GOUTELLE (2,3)
(1) Service Anesthésie Reanimation Medecine Intensive, Groupement Hospitalier Sud, Hospices Civils de Lyon, Pierre Benite, FRANCE ; (2) Service Pharmacie/Pharmacologie, Groupement Hospitalier Nord, Hospices Civils de Lyon, Lyon, FRANCE ; (3) CNRS UMR 5558 LBBE, Université Lyon 1, Lyon, FRANCE ; (4) Service des maladies infectieuses et tropicales, Groupement Hospitalier Nord, Hospices Civils de Lyon , Lyon, FRANCE ; (5) Inserm U111, CNRS UMR 5308, Centre International de Recherche en Infectiologie, Lyon, FRANCE ; (6) Laboratoire de Pharmacologie toxicologie, Groupement Hospitalier Sud, Hospices Civils de Lyon , Lyon, FRANCE","contentIntroduction":"Fluconazole pharmacokinetics (PK) may be altered in critically ill patients, but changes and implications for drug dosing remain unclear. We aimed to describe the PK and dosage requirements of fluconazole in intensive care unit (ICU) patients.","contentPatientsMethods":"This was a PK study performed in a ICU over 1 year. All patients who were prescribed fluconazole with at least two measured concentrations were included. A second dataset from a medical unit was also analysed for comparison.\n Population PK modelling was performed by with Monolix software. Classical criteria were used for model evaluation including goodness-of-fit and simulation-based diagnostics. Patients’s covariates were investigated. Dosing simulations were performed with the final model with Simulx software. Various loading (LD) and maintenance doses (MD) were evaluated, and probability of target attainment (PTA) was computed in simulated patients (n=1000). PK targets were set as a trough concentration (Cmin) of 15 mg/L and a daily AUC of 400 mg.h/L?","contentResultats":"A total of 202 plasma concentrations were available. They were 33 men and 19 women, with mean age of 61 ± 16 years and mean initial weight of 72 ± 21 kg. 59% of patients had proven invasive candidiasis (C.albicans 35%, C.tropicalis 8%) and 4% has cryptococcosis. In ICU patients, a LD of 800 mg was administered in 83% of patients. \n Data were best described with by a one-compartment model with first-order elimination. The mean (CV%) of body clearance (CL) and volume of distribution (Vd) parameters were as follows: 0.46 L/h (56%) and 40.72 L (10%). ICU hospitalisation was associated with a 80% increase in CL. \n The optimal dosage regimen was based on a LD of 800mg q12h over the first 24h followed by a MD of 600 mg/24h. This dosage was associated with median [percentiles 5th-95th] Cmin of 29.5 mg/L [19.2-37.3] at 24h and 30.9 mg/L [8,6-62,8] at 120h and a median AUC of 583.7 [461.4-706.5] at 24h and 895.0 mg.h/L [356.8-1597.0] at 120h. PTA at 24h and 120h were as follows 98.7% and 99.9% for Cmin; 99.2% and 93.4% for AUC, respectively. Only 6% of patients had a concentration over 80 mg/L after 5 days.","contentDiscussion":"We identified increased fluconazole clearance in ICU patients. LD and MD higher than currently recommended are necessary to achieve PK/PD targets in most patients.","contentConclusion":"This study confirms interindividual variability of fluconazole PK and the need for higher dosage in ICU patients. Early therapeutic drug monitoring may be useful for dosage individualization","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOHE Julien"},{"id":99389,"num":"A34394ST","reference":"FC-055","title":"Factors associated with failure to achieve meropenem plasma concentration target in critically ill patients","formatedAuthors":"Sarah TOURNAYRE (1), Olivier MATHIEU (1), Maxime VILLIET (1), Kada KLOUCHE (1), Romaric LARCHER (2)
(1) CHU MONTPELLIER, Montpellier, FRANCE ; (2) CHU NIMES, Nimes, FRANCE","contentIntroduction":"Optimal management of septic shock requires prompt and adequate administration of broad-spectrum antibiotic therapy, ensuring that effective therapeutic levels are achieved. We aimed to determine factors associated with failure to achieve meropenem plasma concentration target in critically ill patients.","contentPatientsMethods":"Between January 2019 and March 2020, charts of all patients admitted in medical ICU for septic shock and treated with meropenem and who had at least one meropenem plasma concentration measurement were reviewed. Adequate target meropenem plasma concentration was ranged from 10 to 50 mg/L. Factors associated with meropenem plasma concentration target non-attainment were assessed by multivariable logistic regression (R software version 4.1.2).","contentResultats":"117 meropenem plasma concentrations were measured 3 days after initiation of meropenem or change on its dosage regimen, in 70 ICU patients. Meropenem was administered by prolonged intermittent infusion in 34 patients and by continuous infusion in 36. Factors independently associated with failure to achieve 10 mg/L of meropenem plasma concentration were female sex, age under 65, prolonged intermittent rather than continuous infusion and low daily doses of meropenem (Figure 1). Factors associated with plasma concentrations above 50 mg/L were low body weight, renal clearance < 25 ml/min and higher daily doses of meropenem. Of note, only 3 patients had neurotoxicity.","contentDiscussion":"","contentConclusion":"In ICU patients, age< 65 years old, female sex, prolonged intermittent infusion and low dose of meropenem were significantly associated with failure to achieve meropenem plasma concentration target. Some patients experienced a high meropenem plasma concentration but few of them had clinical signs of toxicity. Our results suggest to prefer continuous infusion of meropenem over 24 hours rather than prolonged intermittent infusion, particularly in patients with normal or increased renal clearance.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Abdul-Aziz, M.H., Alffenaar, JW.C., Bassetti, M. et al. Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#. Intensive Care Med 46, 1127–1153 (2020)","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Li C, Du X, Kuti JL, Nicolau DP..Clinical pharmacodynamics of meropenem in patients with lower respiratory tract infections. Antimicrob Agents Chemother 51:1725–1730 (2007)","presentateur":"TOURNAYRE Sarah"},{"id":99390,"num":"A34034SS","reference":"FC-056","title":"Optimisation of piperacillin-tazobactam dosing regimen for critically-ill patient with sepsis: the OPT-TAZ population pharmacokinetics study.","formatedAuthors":"Sacha SARFATI (1), Julien WILS (1), Dorothée CARPENTIER (1), Christopher NILES (2), Philippe GOUIN (1), Clément BRAULT (3), Laurent IMBERT (1), Béduneau GAËTAN (1), Saad NSEIR (2), Sandrine DAHYOT (1), Benoit MISSET (4), Fabien LAMOUREUX (1)
(1) CHU de Rouen, Rouen, FRANCE ; (2) CHRU de Lille, Lille, FRANCE ; (3) CHU d'Amiens, Amiens, FRANCE ; (4) CHU de Liège, Liège, BELGIQUE","contentIntroduction":"In critically-ill patient with sepsis, the piperacillin-tazobactam (pip-taz) combination is one of the most used antibiotics. Although pharmacokinetics of pip-taz exhibits very high inter-individual variability mainly based on volume of distribution, renal clearance, patient’s weight and serum albumin level, a standard dosing protocol is generally used (1). Moreover, these covariates are highly variable in sepsis and predictive algorithms based on clinical and biological parameters may help to optimise dosing and improve outcomes.\n The aim of the study is to use a population pharmacokinetics study to build a Bayesian model predicting the optimal dosing regimen of pip-taz in sepsis patients.","contentPatientsMethods":"The OPT-TAZ (optimisation of pip-taz) study is a prospective multicentre open-label non-comparative cohort study designed with a 60-patient learning cohort and a 30-patient validation cohort. Patients will be included prospectively in 4 ICUs in France. The protocol plan to analyse pharmacokinetics of 60 patients then development of a predictive model validated on 30 patients. We present here the analysis of 60 first patients. Standard dosing of pip-taz 4g/0,5g each 6h (group 1) or 8h (group 2) in 3h infusion has been chosen according to clinician choice. Serum concentration of piperacillin and tazobactam has been measured at H0, 1.5, 3, 4, 5 (G1) or 6 (G2), 6 (G1) or 8 (G1), 12 (G1) or 16 (G2), 24, 48 and 120 with a liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).","contentResultats":"In our cohort, we showed that pharmacokinetics of pip-taz present a very high inter-individual variability. Residual concentration was lower than recommended target concentration in more than 50% of cases. Dosing of 4g/0.5g every 8h and augmented renal clearance were risk factor for failure of PK/PD target attainment. PK of piperacillin and tazobactam show a strong association and tazobactam concentration was of the order of 10% of piperacillin concentration.","contentDiscussion":"","contentConclusion":"In conclusion, pip-taz dosing regimen must be adapted to patient characteristics. Creatinine clearance is one of the most important covariate to take into consideration for dose adaptation. The dose of 4g/0.5g each 8h must be considered of high risk of failure of PK/PD attainment in patient with no impaired renal function. Therapeutic drug monitoring is an essential tool to assess the match of dosing regimen with PK/PD target.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1) Huttner A, Harbarth S, Hope WW, Lipman J, Roberts JA. Therapeutic drug monitoring of the ?-lactam antibiotics: what is the evidence and which patients should we be using it for? J Antimicrob Chemother2015;70(12):3178?83.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SARFATI Sacha"},{"id":99391,"num":"A34592JB","reference":"FC-057","title":"Should we really ban 3rd generation cephalosporin (C3G) use for the treatment of Enterobacter cloacae infection in ICU patients?","formatedAuthors":"Juliette BERNIER (1), Jacques TANKOVIC (1), Antoine VILLA (1), Tomas URBINA (1), Vincent BONNY (1), Paul GABARRE (1), Hafid AIT OUFELLA (1), Eric MAURY (1)
(1) CHU Saint Antoine , Paris, FRANCE","contentIntroduction":"Limiting the ecological impact of antibiotics through accurate prescription is one of the major goals of antibiotic stewardship policy. However, an antibiotic-sparing strategy must not have a potential deleterious impact on patient’s prognosis.\n \n Group 3 Enterobacteriaceae possess the AmpC gene encoding a cephalosporinase. Antibiotic therapy with a 3rd generation cephalosporin (C3Gs) might lead to treatment failure when cephalosporinase hyperproducing mutants (Hcase) emergence occurs making them resistant to all penicillins and C3Gs. Thus, experts recommendations advise against the use of C3Gs as monotherapy in this case (1). This risk would be increased for Enterobactercloacaespecies. This statement, based on old studies, is now being debated (2).\n \n This study aimed at evaluating mutants Hcase emergence when treating Enterobacter cloacaecomplex wild-type infections in ICU patients with C3Gs.","contentPatientsMethods":"Methods: We performed a multicenter retrospective study including microbiological files of patients more than 18, admitted to intensive care unit, between January 2015 and August 2021, and who were treated for wild-type Enterobacter cloacaeinfection and assessed mutants emergence defined by a subsequent sample finding mutants Hcase emergence whatever clinical evolution.","contentResultats":"Among the 5275 Enterobacter cloacaespecies found from the microbiology files during the study period, 373 were associated to infections occurring in ICU patients and finally 165 ICU patients infected with C3Gs susceptible E cloacaewere included in the analysis. C3Gs resistance emergence was observed in 19 cases (11.5%),13 being related to Hcase mechanism and 6 to extended spectrum beta-lactamase (ESBL) production.\n C3G were used in 56 cases (35%) before identification (n=12), after identification (n=18) or exclusively (n=26). Cefepime was used in 67 cases (41%) before identification (n= 11), after identification (n=28), exclusively (n=21), or combined with a fluoroquinolone (n=3), an aminoglycoside (n=3) or sulfamethoxazole (n=1).\n Mutants Hcase emergence occurred most often after an exclusive treatment by cefotaxime (n=5), cefepime (n=2), tazocillin (n=3). Three were observed following tazocillin/ aminoglycoside association (n=1), tazocillin followed by sulfamethoxazole(n=1) or cefepime/fluoroquinolone association (n=1). None was observed after carbapenem use. \n \n Considering patients receiving monotherapy following identification, mutants Hcase emergence was more frequent in the C3G group than in the cefepime group (11,4 vs 4% respectively, (p=0,3).","contentDiscussion":"","contentConclusion":"Enterobacter cloacae mutants Hcase emergence could be more frequent following C3G use than cefepime. The data reported here are not significantly different but are obtained on a limited population. A prospective study would be necessary to answer this question.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1195","session":"FLASH COM - Anti infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1. 2021. CASFM / EUCAST AVRIL 2021 V1.0. Société Française de Microbiologie. https://www.sfm-microbiologie.org/2021/04/23/casfm-avril-2021-v1-0/. Retrieved 23 January 2022.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"2. Mizrahi A, Delerue T, Morel H, Le Monnier A, Carbonnelle E, Pilmis B, Zahar JR. 2020. Infections caused by naturally AmpC-producing Enterobacteriaceae: Can we use third-generation cephalosporins? A narrative review. International Journal of Antimicrob","presentateur":"BERNIER Juliette"},{"id":99392,"num":"A34765DR","reference":"FC-058","title":"Anticoagulation, thromboembolic and bleeding events in COVID-19 VV ECMO patients in the French Territories in the Americas","formatedAuthors":"Laura DAOUD (1), Shazima VALLY (1), Hatem KALLEL (2), Agathe CHAPLAIN (1), Jonathan FLORENTIN (1), Bruno MEGARBANE (3), Hossein MEHDAOUI (1), Ruddy VALENTINO (1), Dabor RESIERE (1)
(1) Centre Hospitalier Universitaire, Fort-De-France, MARTINIQUE ; (2) Cayenne General Hospital, French Guiana, Cayenne, GUYANE FRANCAISE ; (3) Lariboisière Hospital, Paris University,, Paris, FRANCE","contentIntroduction":"Background: \n Since December 2019, COVID 19 has affected more than 400 million people and caused more than 5 million deaths, causing a truly global pandemic. While most people with COVID 19 will have a minor or moderate form of the disease, some people will develop severe acute respiratory distress syndrome (ARDS), requiring admission to intensive care and the use of mechanical ventilation ( VM) and sometimes Extracorporeal membrane oxygenation (ECMO). However, COVID-19 has been associated with an increased risk of thromboembolic and bleeding events, and heparin resistance during ECMO treatment in critically ill patients admitted to the intensive care unit (ICU). The therapeutic target for anticoagulation under veno-venous ECMO is not really known. The anticoagulant treatment of choice according to the ELSO recommendations is unfractionated heparin with anti-Xa targets between 0.2 and 0.4. The objective of this cohort study was to evaluate the association between severe COVID 19 infection and the occurrence of thromboembolic and bleeding complications following V-V ECMO","contentPatientsMethods":"We conducted a monocentric retrospective observational study in the ICU department of the University Hospital of Martinique from January 2020 to December 2021. Our center has an on-call ECMO mobile unit (UMAC) which includes a cardiothoracic surgeon and a perfusionist nurse. Requests for veno-venous ECMO French West Indies (Guadeloupe, Martinique, and French Guyana) are regulated by the intensivist on duty at the Martinique University Hospital.","contentResultats":"We included the records of 40 patients with 25 COVID patients and 15 non-COVID patients COVID patients over the period January 2020 to December 2021. Six non-COVID patients were excluded: 3 for deaths within 24 hours, one patient with acute myeloid leukemia type 3, and 2 patients with a contraindication to heparin therapy. The median age was 46 years for Covid patients et 49 for non covid patients. COVID patients experienced thromboembolic complications in 55% of cases (11) and non-COVID patients in 24% of cases (2) p=0.1","contentDiscussion":"","contentConclusion":"Our study confirms that the management of anticoagulation in V-V ECMO represents a particular challenge in COVID patients who seem to be at increased risk of thromboembolic risk complications without sparing the bleeding consequences of the assistance. On the other hand, the difference in thromboembolic and hemorrhagic complications in our two groups was not significant","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"RESIERE Dabor"},{"id":99393,"num":"A34712AS","reference":"FC-059","title":"Bilateral acral ischemia in COVID-19 patients: a peculiar symptom and treatment options","formatedAuthors":"Ameni SGHAIER (1), Sirine RHAIEM (1), Amira JAMOUSSI (1), Samia AYED (1), Emna RACHDI (1), Fatma JARRAYA (1), Mohamed BESBES (1), Jalila BEN KHELIL (1)
(1) Hopital Abderrahman Mami, Ariana, TUNISIE","contentIntroduction":"Although primarily a respiratory virus, SARS-CoV-2 has shown clear impact on hemostasis, often resulting in hypercoagulability state. Deep vein thrombosis, pulmonary embolism and arterial occlusion have all been increasingly reported and investigated during the COVID-19 pandemic. Few studies have however focused on the occurrence of bilateral acral ischemia (BAI). The aim of our study was to examine the characteristics of COVID-19 patients who developed BAI, as well as the various therapy options that might be offered to them.","contentPatientsMethods":"We conducted a retrospective study including patients admitted to our intensive-care unit for acute respiratory distress (ARDS) due to COVID-19 between January and August 2021. Clinical characteristics, laboratory findings and vasopressive treatment doses were recorded and used to compare between patients who developed BAI and those who did not. Fischer bilateral exact test and Mann-Whitney-u test were used for comparison between groups.","contentResultats":"During the study period, 398 patients were admitted; 238 male and 160 female. Of these patients, 8 developed BAI (7 men). Mean age was 67 years. Medical history of diabetes was present in 7 patients, and hypertension in all 8 patients. All patients who developed BAI had severe ARDS. Only one patient remained on non-invasive ventilation support at the time of BAI occurrence and until discharge. The main affected sites of BAI were fingers and toes although ear lobules were also involved in 3 patients. The mean time to development of BAI starting from the day of admission was 4.9 days. Among patients who were intubated, the mean time of BAI occurrence after intubation was 1.2 days. 4 patients were not under any vasopressive treatment at the time of BAI development. The mean norepinephrine dose among the other 4 patients was 0.65mg/h. When compared to the other group of patients, there was no statistically significant difference in gender (p=0.12), median age (56 vs 67; p=0.054), baseline prothrombin time levels (p=0.08), D-Dimer levels (p=0.13), platelet count (p=0.22) and blood fibrinogen levels (p=0.061) when available. Survival rates between the two groups were not statistically significant (196 vs 1 patient; p=0.068). Anticoagulant treatment using heparin was given to 4 patients, with only one patient improving over the course of 10 days. One patient received thrombolysis for subsequent pulmonary embolism with improvement in less than 2 days.","contentDiscussion":"","contentConclusion":"BAI has been increasingly reported in critically-ill COVID-19 patients with no apparent other risk factors to predict its occurrence and limited options for treatment and prevention.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SGHAIER Ameni"},{"id":99394,"num":"A34534GB","reference":"FC-060","title":"Comparative profiles of routine and specialized biomarkers of coagulopathy and endotheliopathy in moderate and severe COVID-19 disease: a prospective observational study","formatedAuthors":"Giovanni BOUSQUET (1), Romaric LACROIX (3), Laurie PAHUS (1), Sabine VALERA (1), Nathalie HEZARD (2), Laurent ARNAUD (3), Evelyne ABDILI (3), Karine BAUMSTARCK (4), Pascal CHANEZ (1), Françoise DIGNAT-GEORGE (3), Laurent PAPAZIAN (1), Jean-Marie FOREL (1), Sami HRAIECH (1), Pierre MORANGE (2), Christophe GUERVILLY (1)
(1) Centre Hospitalier Universitaire de Marseille - Nord, Marseille, FRANCE ; (2) Centre Hospitalier Universitaire de Marseille - La Timone, Marseille, FRANCE ; (3) Centre Hospitalier Universitaire de Marseille - La Conception, Marseille, FRANCE ; (4) Faculté de Médecine de Marseille - La Timone, Marseille, FRANCE","contentIntroduction":"Endothelial injury and coagulation activation are prominent axis in coronavirus disease 19 (COVID-19) pathogenesis. However, few studies have compared comprehensive profiles of biomarkers of coagulopathy/endotheliopathy with regard to the initial severity of COVID-19 and the time course of the disease","contentPatientsMethods":"In a prospective longitudinal study, we explored coagulation and endothelial function biomarkers in two cohorts of severe and moderate COVID-19 patients and according to their respective outcomes.","contentResultats":"We found that Tissue factor pathway inhibition (TFPI), Extracellular vesicles – tissue factor (EV-TF), von Willebrand factor antigen (VWF:Ag) and soluble thrombomodulin (sTM) at admission were associated with disease severity. With regard to outcome, D-dimers, TFPI, EV-TF, VWF:Ag/ADAMTS13 ratio and sTM at admission, at day 3 and at day 7 were associated with death and mechanical ventilation. TFPI with a cut-off value of 37.5 ng/mL had 87% sensitivity and 94% specificity and EV-TF with a cut-off value of 13 fM had 87% sensitivity and 83% specificity. ROC curves analysis for severe outcome was significant with AUC = 0.90 for TFPI and AUC = 0.88 for EV-TF (p < 0.001 for both).","contentDiscussion":"","contentConclusion":"We found a specific profile of specialized biomarkers of coagulopathy/endotheliopathy associated with the severe forms of COVID-19 and its clinical outcome. We identified TFPI and EV-TF to be of potential interest in stratifying patients’ risk or to design specific treatment targeting coagulation pathways. Additional studies are warranted to confirm our results","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HRAIECH Sami"},{"id":99395,"num":"A34594SF","reference":"FC-061","title":"Bedside ACT anticoagulation monitoring in patients infected with SARS COV2 comparing to anti Xa activity","formatedAuthors":"Anass MOUNIR (1), Salma FALAHI (1), Ismail EL MOKHTARI (1), Rachid CHERKAB (1), Chafik EL KETTANI (1), Houcine BARROU (1)
(1) Réanimation chirurgicale P17, CHU IBN ROCHD, Casablanca, MAROC","contentIntroduction":"Patients with coronavirus disease 2019 appear to be at high risk for thrombotic disease in both venous and arterial circulations due to excessive inflammation, platelet activation, endothelial dysfunction, and immobility. Anti-Xa and aPTT are prone to monitor therapeutic range of unfractionated heparin of patients with COVID-19 and severe illness. These biological parameters are certainly effective but are not momentary. Hence the idea of proposing ACT (Activated Clotting Time), as an element for monitoring anticoagulation in patients infected with SARS COV2, given its multiple advantages: simple, fast, inexpensive, and which can be done in bed side","contentPatientsMethods":"We performed a study comparing the results of anticoagulation monitoring by ACT with anti Xa and TCA activity in 20 patients infected with Covid 19 and treated with curative anticoagulation (LMWH 0.8UIx2/day) over a period of 1 month. We excluded from the study patients with potentials that could interfere with TCA results, which are patients with: Hypofibrinogenaemia, clotting factor deficiencies, haemodilution, Aprotinin, thrombocytopaenia, qualitative platelet abnormalities, oral anticoagulants","contentResultats":"Our results are shown in Table1\n The mean age of the population was 54±10. 50% of the patients were diabetic, 25% were hypertensive, one patient was asthmatic, and one patient had dyslipidemia. 50% of patients had parenchymal involvement ≥75%. 35% of patients presented a high risk of thromboembolism. No agreement was found between ACT results and anti Xa activity in our sample. In contrast, in 95% of cases, there was a linear trend between ACT and TCA results","contentDiscussion":"The ACT is routinely used to monitor anticoagulation during cardiopulmonary bypass surgery and endovascular procedures. ACT is determined predominantly by the anti-IIa activity of the anticoagulant. Thus, ACT is higher with heparin or bivalirudin than with LMWH for the same intensity of anticoagulation. However, ACT can be used to monitor LMWH anticoagulation with appropriate adjustments. Several studies have attempted to compare the concordance between ACT results with anti Xa and TCA activity in patients on low-grade UFH anticoagulation. They have shown that In Intensive care unit patients, no relationship between ACT and either UFH dose, aPTT and anti-Xa was observed. All the studies that were found were in IV anticoagulation with UFH. The literature remains very limited about monitoring by ACT for anticoagulation by LMWH","contentConclusion":"Covid 19 infection presents a problem with the management of anticoagulation. The biological monitoring parameters are effective but are not momentary. 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(1) Service de réanimation Médicale Hôpital Régional de Zaghouan, Zaghouan, TUNISIE ; (2) Département pharmacie Hôpital Régional de Zaghouan, Zaghouan, TUNISIE ; (3) service de pneumologie Hôpital Régional de Zaghouan, Zaghouan, TUNISIE ; (4) Faculté de médecine de Tunis, Université Tunis El Manar, Tunis, TUNISIE","contentIntroduction":"Several studies have demonstrated that endothelitis is prominent in COVID-19.Sulodexide (glycosaminoglycan with endothelial protective, vascular anti-inflammatory and antithrombotic activities) was identified to be helpful in hypoxemic patients\n aim of this study was to assess contribution of sulodexide addition in severe SARS-CoV-2 pneumonia and to determine its impact on prognosis","contentPatientsMethods":"Double-arm interventional clinical trial conducted at the medical intensive care unit (ICU) of the regional hospital of Zaghouan (Tunisia) from April 2021 to December 2021, after approval of the ethics committee. Consenting COVID-19 patients over 18 years were included. Two groups were identified: Group 1 (G1) interventional group and Group 2 (G2) control. Sulodexide (500 LSU) was administered from the first day of ICU hospitalization to discharge for a total of 21 days. Epidemiological and prognostic data were analyzed. The study was conducted anonymously. No conflict of interest to be declared.","contentResultats":"During the study period, 149 patients were admitted with severe SARS-CoV-2 pneumonia. 72 patients agreed to participate in the clinical trial (G1). The rest defined the control group. On admission, the two groups were comparable in terms of demographic characteristics, clinical presentation and initial severity. Comparison of outcome parameters showed that patients in group 1 had developed less thromboembolic complications (23.1% vs 39.6%, p=0.016), need to invasive mechanical ventilation (16.8% vs 21.3%, p=0.031), with lower mortality in G1 (19% vs 36%, p=0.047). More intra-hospital cardiovascular complications were noted in G2 (37% vs 12% p=0.03). There were no significant differences in terms of bleeding complications’ occurrence, hemodynamic instability, incidence of healthcare-associated infections, barotrauma complications and length of ICU stay. Multivariate analysis showed that sulodexide use was an independent protective factor against thromboembolic events (OR=0,57;IC à 95% [0.6-0.8] ;p=0,04 ) .Follow-up of patients after three months of discharge, showed no difference in terms of cardiovascular complications, or post-COVID effects.","contentDiscussion":"","contentConclusion":"In this preliminary study, it appears that sulodexide may reduce the risk of thromboembolic and cardiovascular complications in severe COVID patients without affecting the final outcome. Further prospective, multicentre studies with endothelial function studies are needed to confirm this contribution.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BEN ISMAIL Khaoula"},{"id":99397,"num":"A34309pg","reference":"FC-063","title":"Impact of corticosteroids on coagulation profile of critically ill COVID-19 patients - a before-after study","formatedAuthors":"Paul GABARRE (1), Tomas URBINA (1), Sibylle CUNAT (2), Hamid MERDJI (2,3), Vincent BONNY (1), Jean-Rémi LAVILLEGRAND (1,4), Lisa RAIA (1), Naike BIGE (1), Jean-Luc BAUDEL (1), Eric MAURY (1), Bertrand GUIDET (1), Julie HELMS (2,3), Hafid AIT-OUFELLA (1,4)
(1) Hôpital Saint Antoine, Paris, FRANCE ; (2) Hôpital civil , Strasbourg, FRANCE ; (3) INSERM, UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, FRANCE ; (4) INSERM U970, Centre de Recherche Cardiovasculaire de Paris (PARCC), Paris, FRANCE","contentIntroduction":"Several studies have reported an increased risk of thrombotic events in COVID-19 patients, but the pathophysiology of this procoagulant phenotype remains poorly understood. In addition to direct virus-induced endothelial injury, systemic release of pro-inflammatory cytokines may be involved. We hypothesized that corticosteroids may attenuate this procoagulant state through their anti-inflammatory effects.","contentPatientsMethods":"We conducted a before/after bi-centric cohort study among ICU patients hospitalized for severe COVID-19 and receiving therapeutic anticoagulation by unfractionated heparin (UFH). Before and after the standardized use of dexamethasone (DXM), we compared inflammatory and coagulation profiles, as well as the kinetics of heparin requirement, adjusted for weight and anti-Xa activity.","contentResultats":"Eighty-six patients were included, 35 in the no-DXM group, and 51 in the DXM group. At admission, CRP and fibrinogen levels were not different between groups, neither were UFH infusion rates. At day 3 after ICU admission, CRP (178 ± 94 mg/L vs 99± 68 mg/L, p<0.0001) and fibrinogen (7.2 ± 1.4 g/L vs 6.1 ± 1.4 g/L, p=0.0001) significantly decreased in the DXM group, but did not in the no-DXM group. From day 4, UFH infusion rates became lower in the DXM group (Day 4: 435 ± 190 vs 360 ± 96 UI/kg/24hr p=0.038) without any significant difference in plasma anti-Xa activity. CRP variations correlated with heparin dose variations between Day 0 and Day 3 (r=0.39, p=0.009). Finally, the incidence of venous thromboembolic events during in-ICU stay was significantly reduced in the DXM group (4 vs. 43%, p<0.0001).","contentDiscussion":"","contentConclusion":"In this before-after bi-centric cohort of critically ill COVID-19 patients, dexamethasone use was associated with a decrease in both pro-inflammatory and procoagulant profile.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GABARRE Paul"},{"id":99398,"num":"A34639ht","reference":"FC-064","title":"Pulmonary embolism in patients with COVID-19 versus non COVID-19 pneumonia","formatedAuthors":"Hager TOUJ (1), Soumaya SAAD (1), Ines SEDGHIANI (1), Henedi KDEYMI (1), Khalil AOUAINI (1), Rym CHELBI (1), Nebiha BORSALI FALFOUL (1)
(1) hôpital habib thameur, Tunis, TUNISIE","contentIntroduction":"We aim to compare epidemiological, clinical and prognostic characteristics of patients diagnosed with pulmonary embolism (PE) at the emergency department (ED), which we divided into two groups: patients with confirmed COVID-19 pneumonia versus those without it.","contentPatientsMethods":"We conducted a single centre, retrospective observational study in the period between April 2020 and February 2022 .\n We included patients over the age of 18 years admitted at the ED and diagnosed with PE following computed tomography pulmonary angiography (CTPA).\n SARS-CoV2 pneumonia was confirmed by RT-PCR performed in all patients included in our study.\n Patients were divided into two groups: those affected with COVID-19 Pneumonia and those not affected by it.\n Patient's demographics, comorbidities, clinical state and prognosis were collected in both.","contentResultats":"144 patients were included. The mean age was 68 ± 15 years with a sex-ratio of 0.9.\n 79 patients (55%) were diagnosed with confirmed COVID-19 pneumonia.\n The mean length of stay at ED was 7 days. The clinical characteristics of both groups are presented in table 1.\n The intra-hospital mortality rate was 30%.","contentDiscussion":"","contentConclusion":"The association of SARS-CoV-2 pneumonia and PE leads to a higher morbidity. Our findings therefore suggest that the phenotype of COVID-19 associated PE indeed differs from PE in patients without COVID-19.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1196","session":"FLASH COM - COVID-19 : coagulation","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SEDGHIANI Ines"},{"id":99399,"num":"A34610QQ","reference":"FC-065","title":"Neutrophil phenotypes and microbicidal activity in SARS-CoV-2 associated ARDS patients","formatedAuthors":"Quentin QUELVEN (1), Murielle GRÉGOIRE (2), Valentin COIRIER (1), Mikael ROUSSEL (2), Karin TARTE (2), Jean-Marc TADIÉ (1), Mathieu LESOUHAITIER (1)
(1) CHU Rennes, Pontchaillou, Rennes, FRANCE ; (2) Unitée MIcroenvironment, Cell differentiation, iMmunology And Cancer (MICMAC), UMR INSERM 1236, Rennes, FRANCE","contentIntroduction":"The SARS-CoV-2 infection can lead to a severe acute respiratory distress syndrome (ARDS) with prolonged mechanical ventilation and high mortality rate, sharing clinical and biological features with sepsis-induced immune dysfunction. Since neutrophils play a critical role in host defense against infections, the aim of our study was to investigate phenotypic and functional alterations of neutrophils in patients with SARS-CoV-2 associated ARDS.","contentPatientsMethods":"SARS-CoV-2 associated ARDS patients admitted to the ICU, without known immunosuppression, were included. Neutrophil phenotypic maturation and functions (migration, adhesion, Neutrophil Extracellular Trap (NET) release, Reactive Oxygen Species (ROS) production, bacteria/aspergillus killing and phagocytosis) were evaluated within 24 hours of ICU admission and at day 7. Furthermore, in a second set of experiments, we investigated the effects of bronchoalveolar lavage (BAL) fluids from SARS-CoV-2 associated ARDS patients on neutrophils.","contentResultats":"Forty-nine patients were included (Table 1). We found that SARS-CoV-2 associated ARDS induced a systemic inflammation with an increase of circulating mature neutrophils. However, we found a significant decrease in CD66b expression (a marker of granulocyte activation involved in adhesion to endothelial cells, degranulation, and reactive oxygen species (ROS) production). Neutrophil antifungal activity against Aspergillus fumigatus was not impaired in patients with SARS-CoV-2 associated ARDS.","contentDiscussion":"","contentConclusion":"Although neutrophils ROS production from patients with SARS-CoV-2 associated ARDS was significantly decreased our results do not support that the increase risk of invasive aspergillosis is linked to neutrophil dysfunction.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1197","session":"FLASH COM - Biomarqueurs dans le COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"QUELVEN Quentin"},{"id":99400,"num":"A34528VB","reference":"FC-066","title":"High plasma hyaluronate is associated with mortality in critically-ill patients with SARS-CoV-2 infections","formatedAuthors":"Vincent BONNY (1), Tomas URBINA (1), Alexandre ELABBADI (2), Paul GABARRE (1), Louaï MISSRI (1), Sebastien EHRMINGER (1), Cyrielle DESNOS (2), Bertrand GUIDET (1), Eric MAURY (1), Guillaume VOIRIOT (2), Yannick CHANTRAN (1), Nathalie MARIO (1), Jérémie JOFFRE (1), Hafid AIT-OUFELLA (1)
(1) Hôpital Saint-Antoine, Paris, FRANCE ; (2) Hôpital Tenon, Paris, FRANCE","contentIntroduction":"SARS-CoV-2 infection could be responsible for life-threatening severe lung damage with inflammatory cell infiltration, increased vascular permeability and fluid leakage. Hyaluronic acid (HA) is an extracellular matrix polysaccharide, detected in large amounts in lung alveoli in lethal cases of COVID-19 patients. HA which is released by inflammatory cells may be involved in the pathophysiology of alveolar exudate formation through fluid retention. We aim to evaluate the relationship between plasma HA levels and the outcome of critically ill COVID-19 patients.","contentPatientsMethods":"We performed an observational, bi-center study including patients admitted to intensive care unit with a confirmed laboratory SARS-CoV-2 infection, for acute respiratory failure between April 2020 and December 2020. Plasma level of hyaluronan was measured by ELISA.","contentResultats":"Overall, 120 patients were included in this study, median age was 62 [53 – 70] years, 25 patients (21%) were female, median SOFA score was 3 [2 – 6] at ICU admission. 76 patients (63 %) required invasive mechanical ventilation. At admission, median PaO2/FiO2 ratio was 157 [112 – 221] mmHg, mortality at day 28 was 20%. Median HA level was 177 [68 – 356] ng/mL at admission. HA levels were 2-fold higher in non-survivors (379 [90 – 914] vs 150 [62 – 283] ng/mL), p = 0.01) whereas C-RP and fibrinogen were not different according to the outcome. HA levels correlated with PaO2/FiO2 (R = - 0.22, p = 0.02, Pearson test) but did not correlate with CRP.","contentDiscussion":"","contentConclusion":"Plasma HA levels were associated with poor outcome in critically ill patients with SARS-CoV-2 infections.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1197","session":"FLASH COM - Biomarqueurs dans le COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BONNY Vincent"},{"id":99401,"num":"A34649LM","reference":"FC-067","title":"Serum complement C3 and C4 prediction of mortality in critically ill COVID19 patients","formatedAuthors":"Linda MESSAOUD (1), Amira JAMOUSSI (1), Samia AYED (1), Emna RACHDI (1), Fatma JARRAYA (1), Sadok YAALAOUI (1), Mohamed BESBES (1), Jalila BEN KHELIL (1)
(1) hôpital Abderrahmen Mami , Ariana , TUNISIE","contentIntroduction":"The complement system has many protective effects against infectious agents following activation during innate, through the alternative and lectin pathways, and acquired, through the classical pathway immunity. \n \n However, adverse events were observed in COVID-19 following activation of the complement system by the prolonged release of pro-inflammatory mediators.\n \n We aimed to investigate ability of serum complement C3, C4 to predict mortality in patients with critical COVID-19.","contentPatientsMethods":"Prospective study carried in respiratory medical intensive care unit of Abderrahmen Mami teaching hospital. It included critically ill patients diagnosed with COVID-19 between September 2020 and December 2021. Complement C3 and C4were measured during the first 24 hours of hospitalization. C3 and C4 complement deficiency was defined respectively by a concentration below 0.9 g/L and 0.16 g/L. Association with ICU mortality was then analyzed.","contentResultats":"During the study period, we enrolled 34 patients. Mean age was of54 ± 13 years and gender ratio of 1.8. The most common comorbidities were diabetes (36 %), obesity (35%) and hypertension 18%). Nineteen patients were transferred to general ward or discharged (survival group) and fifteen died in hospital (non-survival group).\n \n The condition of 9 of these patients (27%) degraded during hospitalization and needed invasive mechanical ventilation. The time from hospital admission to intubation varied from 1 to 8 days (median 1 day). During the first 24 hours, median C3 was 1.72 g/L [0.6 – 2.61], and C4 was 0.38 g/L [0.06 – 0.73]. Six patients(19%) had a C3 deficit and 5 (16%) had a C4 deficit on admission. The overall mortality rate was 56 % and the mean length of hospital stay was 10 days [6-17].\n \n Died patients had lower C3 concentrations in comparison to survivors (1.54 vs 1.85 g/L; p = 0.015). However, no significant difference was found in C4 concentrations (0.36 vs 0.40 g/L; p=0.595) \n \n The level of complement C3 was also lower in patients who required invasive mechanical ventilation (1.42 vs 1.87 p=0.016) compared to the non-invasive ventilation group.","contentDiscussion":"","contentConclusion":"Serum complement C3 and C4 deficiency can be observed in critical COVID-19 patients. C3 concentrations was significantly lower among non-survivors and invasively ventilated patients.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1197","session":"FLASH COM - Biomarqueurs dans le COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MESSAOUD Linda"},{"id":99402,"num":"A34739JA","reference":"FC-068","title":"Early decrease of CD4 and HLA-DR expression on monocytes predicts the severity of COVID-19 pneumonia.","formatedAuthors":"Jerome ALLARDET-SERVENT (1), Ines AIT BELKACEM (2,3), Tewfik MILOUD (3), Lucas BENAROUS (1), Franck GALLAND (2), Philippe HALFON (1), Jean-Louis MEGE (4), Jean-Marc BUSNEL (3), Fabrice MALERGUE (3)
(1) HOPITAL EUROPEEN MARSEILLE, Marseille, FRANCE ; (2) CENTRE D'IMMUNOLOGIE MARSEILLE-LUMINY, Marseille, FRANCE ; (3) BECKMAN COULTER IMMUNOTECH, Marseille, FRANCE ; (4) INSTITUT HOSPITALO-UNIVERSITAIRE DE MALADIES INFECTIEUSES, Marseille, FRANCE","contentIntroduction":"Predicting early the course of COVID-19 pneumonia remains challenging for physicians. Characterization of blood immune cell status may improve patient stratification1. This study investigates the value of a rapid one-step flow cytometry method in patients hospitalized for moderate to severe COVID-19 pneumonia.","contentPatientsMethods":"Thirty patients with laboratory confirmed COVID-19 pneumonia were prospectively included and compared to 19 healthy controls. End-points of interest were the need for intensive care unit (ICU) admission and mechanical ventilation (MV) initiation. Whole-blood immunophenotyping was performed within the first 48 hours of hospital admission using three antibody panels (Beckman Coulter, Brea, USA) focusing on leucocytes (DURAClone IM Phenotyping Basic panel), granulocytes (DURAClone IM Granulocytes panel), and myeloid activation markers (IOTest Myeloid Activation Antibody Cocktail: CD169, CD64, HLA-DR). Leucocyte staining and lysis were performed following the one-step method2. Comparisons were performed using Mann-Whitney U test. Receiver operating characteristic (ROC) analysis was used to determine the area under the curve (AUC) of factors associated with ICU admission and MV requirement. Continuous data are presented as median and interquartile.","contentResultats":"COVID-19 patients were mostly male (87%), aged 61 [50,71] years, and 12 (40 %) were obese. Nine COVID-19 patients (30%) received standard oxygen therapy in the ward while 21 (70 %) required ICU admission. Among ICU patients, 7 (23 %) received high flow oxygen therapy and 14 (47%) required MV of whom 3 also received extracorporeal membrane oxygenation. Four patients (13%) deceased.\n We confirmed a COVID-19 signature including: 1) a reduction of HLA-DR expression; 2) decreased basophils, eosinophils, T-cells, NK cells, and non-classical monocyte count; and 3) an upregulation of CD169, CD64, the adhesion/migration markers (CD62L and CD11b), and the checkpoint inhibitor CD274. COVID-19 patients requiring MV presented significantly lower expression of HLA-DR and CD4 on monocytes, as well as reduced CD8+ T-cell count. These three parameters predicted MV requirement with respective AUC of 0.87, 0.87 and 0.79 but their combination increased the AUC up to 0.991 (Figure 1). Similarly, ICU admission was best predicted by the combination of HLA-DR and CD4 on monocytes with CD4+ T-cell count, yielding an AUC of 0.947","contentDiscussion":"This study further describes the immunophenotypic alterations associated with COVID-19, emphasizes the role of monocytes, and strengthens the clinical potential of a rapid, one-step, flow cytometry method.","contentConclusion":"HLA-DR and CD4 expression on monocytes, when combined to CD4+ and CD8+ T-cells count, may facilitate the early prediction of ICU admission and MV initiation in hospitalized patients with COVID-19 pneumonia.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1197","session":"FLASH COM - Biomarqueurs dans le COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Chevrier, S et al. A Distinct Innate Immune Signature Marks Progression from Mild to Severe COVID-19. Cell Rep Med 2021, 2 (1), 100166.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Ait Belkacem, I et al. One-Step White Blood Cell Extracellular Staining Method for Flow Cytometry. Bio-protocol 2021, 11 (16), e4135–e4135.","presentateur":"ALLARDET-SERVENT Jerome"},{"id":99403,"num":"A34628FR","reference":"FC-069","title":"Lymphocytic alveolitis in severe COVID-19 pneumonia","formatedAuthors":"Faustine REYNAUD (1), Maeva RODRIGUEZ (1), François ARRIVE (1), Anne VEINSTEIN (1), Delphine CHATELLIER (1), Florence BOISSIER (1), Jean-Pierre FRAT (1), Rémi COUDROY (1), Arnaud W. THILLE (1)
(1) CHU de Poitiers, Poitiers, FRANCE","contentIntroduction":"Neutrophil alveolitis has been reported in the early course of mechanically ventilated patients with COVID-191,2. Whereas lymphocytic alveolitis is described in organizing pneumonia, whether this pattern occurs during the course of COVID-19-related respiratory failure is unknown.","contentPatientsMethods":"Retrospective observational cohort study performed in a single-center. All patients with COVID-19-related respiratory failure admitted to our ICU between September 2020 and June 2021 (second and third wave) and who had broncho-alveolar lavage (BAL) were included. BAL was performed for secondary worsening or lack of improvement after excluding ventilator-associated pneumonia or pulmonary embolism. Secondary worsening was defined as a one-point increase on the World Health Organization 7-point Clinical Progression Scale (WHO-CPS) occurring after steroid discontinuation and after a first step of improvement (at least one-point drop on the WHO-CPS). Lack of improvement was defined as no point-drop on WHO-CPS after ten days of steroids. The primary outcome was the prevalence of lymphocytic alveolitis defined by a lymphocyte count at least 20% of total cellular count.","contentResultats":"Among the 182 patients admitted for COVID-19-related respiratory failure over the study-period, BAL was performed in 20 patients with secondary worsening (n=12) or lack of improvement (n=8). As compared to the others, patients who underwent BAL were more likely to be intubated (18 of 20 patients, 90% vs. 76 of 162 patients, 47%; p<0.001), and had longer duration mechanical ventilation (24 days in median [14-39] vs. 10 days [8-15]; p<0.001). \n Among the 20 patients who underwent BAL, 10 (50%) had lymphocytic alveolitis including 50% of patients who had BAL for secondary worsening (6 out of 12 patients), and 50% of patients who had BAL for lack of improvement (4 out of 8 patients). All patients with lymphocytic alveolitis received a second course of steroid therapy after BAL. Mortality was 75% in patients with lack of improvement (3 of 4 patients) and 17% (1 of 6 patients) in those with secondary worsening.","contentDiscussion":"","contentConclusion":"Lymphocytic alveolitis was found in half of patients who underwent BAL for secondary worsening or lack of improvement and was associated with good outcomes when a second regimen of steroid was administered to patients with secondary worsening.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1197","session":"FLASH COM - Biomarqueurs dans le COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Baron A, Hachem M, Tran Van Nhieu J, Botterel F, Fourati S, Carteaux G, De Prost N, Maitre B, Mekontso-Dessap A, Schlemmer F. Bronchoalveolar lavage in patients with COVID-19 with invasive mechanical ventilation for acute respiratory distress syndrome. An","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Cornelissen C, Bergs I, Müller A, Daher A, Kersten A, Balfanz P, Lemmen S, Marx G, Marx N, Dreher M, Müller T. Broncho-alveolar lavage in patients with acute respiratory distress syndrome due to COVID-19. Internal Medicine Journal 51 (2021) 965–967","presentateur":"REYNAUD Faustine"},{"id":99404,"num":"A34475GM","reference":"FC-070","title":"Predictive factors of mortality in critically ill patients with SARS-CoV 2 pneumonia: a prospective study of 301 patients","formatedAuthors":"Giulia MORATELLI (1), Kais REGAIEG (1), Sabrine NAKAA (1), Nesrine FRAJ (1), Myriam KALLEL (1), Amir AL HARACH (1), Laure GAZAIGNE (1), Dany GOLDGRAN-TOLEDANO (1)
(1) Groupe Hospitalier Intercommunal Le Raincy Montfermeil, Montfermeil, FRANCE","contentIntroduction":"We want to describe the epidemiological, clinical and outcome of critically ill patients with SARS CoV2 pneumonia and to identify risk factors for in-hospital mortality in these patients.","contentPatientsMethods":"We conducted a prospective cohort study of critically ill adults admitted into ICU from Mars 2020 to February 2022 for SARS CoV pneumonia.","contentResultats":"A total of 301 patients were admitted into our ICU for acute respiratory failure to SARS CoV 2 pneumonia. Mean age was 62 (25 – 86). Mean delay to ICU hospitalization was 8 (1 – 27) days and mean duration of ICU stay was 8 (1 – 149) days. Mean SAPS was 32 (12 – 75). Sex ratio (M/F) was 2. Mean body mass index was 30 (18 - 68). 56% of patients (n=169) had hypertension (n = 169), 33%(n=100) were diabetics and 11% (n=33) had chronic kidney diseases. Within the study period, 86% of patients (n = 258) have needed non–invasive ventilation and 83% (n = 250) had high flow nasal oxygen as first line therapy. 48% of patients (n = 143) have received mechanical ventilation for a mean duration of 12 days (1 – 47) and 47% (n =67) of them were extubated. 43% of patients (n =129) have needed catecholamine, 14% (n=41) renal replacement therapy and 7,7% (n = 11) ECMO. \n Different immunomodulator’s therapies were used during study period: 41% of patients (n =124) have received dexamethasone 6 mg/day for ten days, 38% (n = 113) have received dexamethasone 0,1 mg/Kg/days for ten days and 8,6% (n = 26) of them have received bolus of methylprednisolone 250mg/days for three days as rescue therapy. We have administrated tocilizumab in 7,3% of patients (n = 22). \n In the univariate analysis, risk factors associated with mortality were age, hypertension, SAPS II, chronic renal diseases, AKI, use of catecholamine and mechanical ventilation. \n In the multivariate analysis, risk factors associated with mortality were mechanical ventilation and use of catecholamine.","contentDiscussion":"","contentConclusion":"Our experience during this pandemic period is similar to the results of most European studies. The use of mechanical ventilation and catecholamine were associated with a poor outcome. More studies are needed on this subject.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MORATELLI Giulia"},{"id":99405,"num":"A34656MM","reference":"FC-071","title":"Epidemiological and Clinical characteristics of 600 COVID-19 patients","formatedAuthors":"Manal MERBOUH (1), Ghizlane EL AIDOUNI (1), Rajae ALKOUH (1), Salma TAOUIHAR (1), Ikram ZAID (1), Sanae EL MEZZIOUI (1), Amine BOUABDELLAOUI (1), Fatima AFTISS (1), Ilias LAARIBI (1), Bahouh CHOUKRI (1), Rajae BENCHAIB (1), Hamza MIMOUNI (1), Mohammed MAARAD (1), Ikram MEKKAOUI (1), Khaoula JEBAR (1), Younes OUJIDI (1), Amine BENSAID (1), Badie DOUQCHI (1), Badie CHETOUANI (1), Bkiyar HOUSSAM (1), Naima ABDA (1), Brahim HOUSNI (1)
(1) CHU Mohammed VI OUJDA,MAROC, Oujda, MAROC","contentIntroduction":"COVID-19 is a global health crisis. The evolution of the disease is unpredictable with disastrous socio-economic consequences. The aim of the present work is to study the epidemiological, clinical, diagnostic, therapeutic and evolutionary aspects, as well as risk factors associated with SARS-CoV-2 infection in 600 patients, admitted to the intensive care unit of a university hospital during the first wave of the pandemic.","contentPatientsMethods":"This is a retrospective descriptive and analytical study conducted on patients with COVID-19 between 22 March and 31 December of 2020. Data were collected using computerized medical records on HOSIX and were exploited by the clinical SPSS software.","contentResultats":"Of 600 patients, the median age was 64 years (IQR 15-100), 403 patients were male (sex ratio= 2.05), 387 patients had a BMI above normal, 191 had a history of hypertension, 188 had a history of diabetes.\n Fever, cough, dyspnea were the predominant symptoms, 379 patients had more than 50% lung involvement on chest CT.\n The majority of patients had desaturation on admission.\n Respiratory distress, lymphopenia, thrombocytopenia, elevated CRP and hyperglycemia were significantly associated with an unfavorable outcome.\n The management was based on synthetic antimalarials associated with azithromycin, corticosteroids ,ventilatory support as well as specific management of complications with a good evolution in 67.5% of cases ,mean duration of hospitalization in the intensive care unit was 8.2 days varying from 2 to 49 days.","contentDiscussion":"","contentConclusion":"The results of our study are consistent with other series. COVID 19 remains a malignant disease if management is delayed and leads to the development of several complications.\n Barrier measures remain the best means of prevention against covid-19.\n Mass vaccination to acquire herd immunity is the way to control this infection.","published_at":"2022-06-16T16:01:22.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:22.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MERBOUH Manal"},{"id":99406,"num":"A34349BP","reference":"FC-072","title":"Prognosis of Critically ill Patients with acute respiratory Failure due to the SARS-CoV-2 501Y.V2 variant : a multicenter retrospective matched cohort study :","formatedAuthors":"Bérénice PUECH (1), Antoine LEGRAND (1), Olivier SIMON (1), Chloé COMBE (1), Marie-Christine JAFFAR-BANDJEE (1), Margot CARON (1), Charles VIDAL (1), Patrick MAVINGUI (1), Renaud BLONDE (1), Yvonnick BOUE (1), Hamza BERGUIGUA (1), Jerome ALLYN (1), Cyril FERDYNUS (1), Nicolas ALLOU (1)
(1) CHU Felix Guyon , Saint Denis, REUNION","contentIntroduction":"The aim of this study was to compare the prognosis of patients with acute respiratory failure (ARF) due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant 501Y.V2 to that of patients with ARF due original strain.","contentPatientsMethods":"This retrospective matched cohort study included all consecutive patients who were hospitalized for ARF due to SARS-CoV-2 in our University Hospital between March 2020 and April 2021. Twenty-eight in hospital mortality was evaluated before and after matching.","contentResultats":"A total of 218 patients with ARF due due to SARS-CoV-2 were enrolled in the study. Of these, 83 (38.1%) were infected with the 501Y.V2 variant. During intensive care stay , 104 (47.7%) patients received invasive machanical ventilation and 20 (92%) patients were supported by venovenous extracorporeal membrane oxygenation. Patients infected with the 501Y.V2 varients were younger (58 [51-68] versus 67 [56-74] years old, p=0.003), had less hypertension (54.2% vs 68.1%, p=0.04) , and had less chronic kidney disease (13.3% vs. 31.9%, p=0.002) than patients infected with the original strain. After controlling for confounding variables (62 matched patients in each group), 28-day mortality was higher in the group of patients infected with the 501Y.V2 variant (30.6%) than inthe group of patients infected with the original strain (19.4%, p=0.04)","contentDiscussion":"","contentConclusion":"In our department, where SARS-CoV-2 incidence remained low until February 2021 and the health care system was never satured, mortality was higher in patients with ARF infected with the 501Y.V2 variant than in patients infected with the original strain.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LEGRAND Antoine"},{"id":99407,"num":"A34713IA","reference":"FC-073","title":"Characteristics and outcome of critically ill COVID-19 patients","formatedAuthors":"Amina HADDED (1), Ilef ALILA (1), Sana KHARRAT (1), Olfa TURKI (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) hopital Habib Bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"The Covid-19 pandemic has hit our country as well as countries around the world since December 2019 with its begining in Wuhan, China. This virus has threatened the life of human beings by attacking various organs, causing especially respiratory distress requiring hospitalization in intensive care unit and causing significant mortality.\n The aim of this study was to describe the clinical characteristics and outcome of patients with coronavirus disease-2019 (COVID-19) hospitalized in intensive care unit (ICU).","contentPatientsMethods":"We conducted a retrospective study in a medical ICU over a period of 16 months [September 2020-December 2021] including patients with SARS-COV2 infection.","contentResultats":"During the study period, 586 patients were included with a mean age of 59.5 ± 14.7 years and a sex ratio of 1.6. The median SAPSII and SOFA score were respectively of 29 ± 14.8 and 4 ± 2.6. Most patients had comorbidities, including hypertension (36 %), obesity (32.1%) and diabetes mellitus (36.2%).\n A total of 419 (71.5%) patients had severe acute respiratory distress syndrom (ARDS). Severe lung damage ranging between 50 and 75% of the lung parenchyma was estimated in 175 patients (30%). 117 (20%) had lung parenchyma damage ≥ 70%. Invasive mechanical ventilation was required in 264 patients (45.1%) for a median of 3 days. During the ICU stay, vasopressor therapy was required in 232 patients (39.6%). Thromboembolic complications were found in 32 (5.5%) patients. Pulmonary embolism was diagnosed in 22 patients (3.8%) and thrombophlebitis in 10 (1.7%). 239 patients (40.8%) developed renal failure during their hospitalization, and only 37 (6.3%) required hemodialysis. Median ICU length of stay was 6 IQR [3–10] days and overall mortality was 49 % (287patients). Multivariate logistic analysis showed that an age older than 60 years, CRP value > 75 mg/l at admission; invasive mechanical ventilation, occurrence of infection or acute kidney injury were independent predictors of mortality in patients with severe COVID-19.","contentDiscussion":"","contentConclusion":"In this cohort of patients admitted to the intensive care unit, COVID-19 pneumonia was associated with high morbidity and mortality rates. The main clinical predictors were age, CRP value at admission, invasive mechanical ventilation, occurrence of infection or acute kidney injury.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALILA Ilef"},{"id":99408,"num":"A34578NT","reference":"FC-074","title":"Epidemiology and demographic profile characteristics and outcome of covid-19 patients in intensive care unit at the medical emergency department","formatedAuthors":"Nabil TABET AOUL (1,2), Djamel ALACHAHER (1,2), Mourad GOULMANE (1,2), Soufiane OUALI DADA (1,2), Nabil SIDI AISSA (1,2), Mohammed AZZA (1,2), Hajer BOUDADI (2)
(1) Faculty of Medicine of Oran, University Oran 1, Oran, ALGERIE ; (2) Medical Emergency Department, University Hospital Center of Oran, Oran, ALGERIE","contentIntroduction":"The recent emergence of COVID-19 has confronted us with an unprecedented global health crisis with a saturation of hospitals, particularly in ICUs and consequently a rate of very high mortality, our first priority is to improve the prognosis particularly with early management.\n The aim of this study was to evaluate the characteristics of COVID-19 patients admitted to ICUs and prognosis factor.","contentPatientsMethods":"We conducted a retrospective analysis of COVID-19 patients mortality and predictive factors of mortality in ICU at the medical emergency department of UHC of Oran in Algeria between 01/01/2021 au 01/01/2022. Non-survivors were compared to survivors using multivariable analysis, we analyzed age, comorbidities, vaccination status, CT scan results, D dimer rate at admission and invasive ventilation.","contentResultats":"During this period between January 2021, to January, 2022, 223 COVID-19 patients required ICU admission with a peak of 26,9 % patients in July and august, In this patients confirmed with COVID-19, a female represented 60% with a sex ratio of 0.66, older patients above 60 years in the majority of cases against only 4% under 40 years, and the majority of patients was Unvaccinated (those who have not received any dose of a COVID-19 vaccine), with presence of comorbidities in 86 % of cases, and the peribronchovascular distribution of lesions, number of zones involved, and especially percentage greater than 50% in 55% cases with a rate D dimer greater than 1000 in 62% were associated with increased risk of ICU admission.\n The mortality of this data was higher (66 %), Non-survivors were older and had more frequently various comorbid diseases (56 % of patients were hypertensive and 43 % were diabetic) than survivors and the use of invasive mechanical ventilation, were independently associated with an increased mortality in ICU using the multivariable analysis.","contentDiscussion":"","contentConclusion":"In our cohort patients with, the mortality was higher particularly in older and had more frequently various comorbid diseases and received invasive mechanical ventilation despite adequate and early management and the initial chest CT scan can predict COVID-19 positivity, ICU admission, mortality, and disease severity.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle 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com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TABET AOUL Nabil"},{"id":99409,"num":"A34341AG","reference":"FC-075","title":"Derivation and validation of the CERES score for the prediction of late intubation in Covid-19","formatedAuthors":"Alexandre GAUDET (1,2), Benoit GHOZLAN (1), Annabelle DUPONT (3,4), Erika PARMENTIER - DECRUCQ (1,2), Constance BAYON (1), Anne TSICOPOULOS (2), Sophie SUSEN (3,4), Julien POISSY (1,5)
(1) CHU Lille, Department of Intensive Care Medicine, Critical Care Center, Lille, FRANCE ; (2) Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d'Infection et d'Immunité de Lille, Lille, FRANCE ; (3) CHU Lille, Service D'hémostase et Transfusion, Centre de Biologie Pathologie, Lille, FRANCE ; (4) Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 EGID, Lille, FRANCE ; (5) Univ. Lille, Inserm U1285, CHU Lille, CNRS, UMR 8576, UGSF, Unité de Glycobiologie Structurale et Fonctionnelle, Lille, FRANCE","contentIntroduction":"Predictive scores assessing the risk of respiratory failure in Covid-19 mostly focused on the prediction of early intubation (1). A combined assessment of clinical parameters and biomarkers of endotheliopathy could allow to predict late worsening of acute respiratory failure (ARF) subsequently warranting intubation in Covid-19 (2).","contentPatientsMethods":"Retrospective single-center derivation (N = 92 subjects) and validation cohorts (N = 59 subjects), including severe Covid-19 patients with non-invasive respiratory support for at least 48h following ICU admission. We used stepwise regression to construct the Covid endothelial and respiratory failure (CERES) score in a derivation cohort, and secondly assessed its accuracy for the prediction of late ARF worsening requiring intubation within 15 days (D15) following ICU admission in an independent validation cohort.","contentResultats":"Platelets, fraction of inspired oxygen and endocan measured on ICU admission were identified as the top 3 predictive variables for late ARF worsening and subsequently included in the CERES score. The area under the ROC curve of the CERES score to predict late ARF worsening was respectively calculated in the derivation and validation cohorts at 0.834 and 0.780 (Figure 1A). A CERES value ≥ 140 showed the best sensitivity to predict late ARF worsening on D15, observed respectively at 1 and 0.93 in the derivation and validation cohorts, while specificity was found at 0.48 and 0.44, respectively. Further, the best specificity for the prediction of late ARF worsening on D15 was observed for a CERES value ≥ 333, being then respectively found at 0.9 and 0.93 in the derivation and validation cohorts, while sensitivity was measured at 0.45 and 0.5 with this cut-off (Figure 1B).","contentDiscussion":"Two distinct clinical applications may be derived from our results. First, we found that a CERES value ≥ 140 has a very high sensitivity for the detection of patients eventually requiring invasive respiratory support. Accordingly, the non-invasive strategy was successful in nearly all patients with a CERES score < 140. We could therefore propose to maintain non-invasive strategies in patients with a CERES score < 140. In the same view, a CERES score ≥ 333, which detected the further need for invasive support with a high specificity, could be used to propose earlier intubation in patients with the highest risk of failure of non-invasive strategies.","contentConclusion":"In patients with severe Covid-19 undergoing non-invasive respiratory support, CERES values < 140 and ≥ 333 appear as accurate predictors of late ARF worsening subsequent requiring intubation.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Prakash J, Bhattacharya PK, Yadav AK, Kumar A, Tudu LC, Prasad K. ROX index as a good predictor of high flow nasal cannula failure in COVID-19 patients with acute hypoxemic respiratory failure: A systematic review and meta-analysis. J Crit Care. 2021 Dec;","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Dupont A, Rauch A, Staessens S, Moussa M, Rosa M, Corseaux D, et al. Vascular Endothelial Damage in the Pathogenesis of Organ Injury in Severe COVID-19. Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1760–73.","presentateur":"GAUDET Alexandre"},{"id":99410,"num":"A34673FJ","reference":"FC-076","title":"Early vs late intubation in COVID-19 acute respiratory distress syndrome","formatedAuthors":"Lynda MESSAOUD (1), Fatma JARRAYA (1), Emna RACHDI (1), Rim JEMMALI (1), Amira JAMOUSSI (1), Samia AYED (1), Jalila BEN KHELIL (1)
(1) hôpital Abderrahmane mami, Ariana, TUNISIE","contentIntroduction":"Although management of acute respiratory failure with coronavirus 2019 disease often involves the use of mechanical ventilation, the optimal time to initiate invasive mechanical ventilation (IMV) remains unknown.\n The aim of this study was to assess the impact of the timing from admission to intubation on mortality in patients with SARS-COV2 acute respiratory distress syndrome (ARDS).","contentPatientsMethods":"This retrospective study was conducted in an intensive care unit (ICU) between March 2020 and September 2021. We included adult patients with ARDS secondary to SARS-COV2 who required IMV. We did not include patients who were intubated prior to admission. The median time to intubation from admission was 72 h. We defined \"early\" intubation as intubation within 72 hours of ICU admission and \"late\" intubation as intubation occurring at any time after 72h. Patients were divided into two groups: early intubation (G1) (≤ 72h) or late intubation (G2) (> 72h) for analysis.","contentResultats":"During the study period, 298 patients required IMV of which 175 were intubated early (58.7%) and 123 were intubated late (41.3%). The 2 groups were comparable in terms of median age (61 ±12 years vs 63 ± 11 years; p= 0.086, G1, G2 respectively) and gender ratio (1.69 vs 2.41, G1, G2 respectively). However, patients in G1 had higher SAPSII at admission (32.3 ±11 vs 28 ± 7; p= 0,002).\n Patients in the G1 had a worse PaO2/FiO2 ratio (median, 100 mmHg vs 130 mmHg; p=10-3), at the time of intubation in comparison with the G2. Lower static compliance (22 ml/mmHg vs 28 ml/mmHg; p=0.562) and higher plateau pressure (29 mmHg vs 22 mmHg; P=0.180) were noted in the G2, although these values were not statistically significant.\n The length of stay in the ICU was similar between both groups (8 days [4-15] vs 13 days [9-18]; p=0.156). Even among survivors who were successfully weaned from mechanical ventilation (n=25; 8.4%), length of stay was similar between both groups (30 days [12-45] vs 31 days [18-41]; G1, G2 respectively; p=0.635). There was no significant difference in mortality between patients in G1 and G2 (57.5% versus 42.5% p=0.159).\n The overall mortality rate was 91.6% and the average length of hospital stay was 11 days [6-17].","contentDiscussion":"","contentConclusion":"An early intubation strategy was not associated with decreased mortality and morbidity compared to late intubation in patients with ARDS due to SARS-COV 2.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1198","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 1","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MESSAOUD Lynda"},{"id":99411,"num":"A34359VJ","reference":"FC-077","title":"Correlation between chest electrical impedance variation and tidal volume in mechanically ventilated patients","formatedAuthors":"Vincent JOUSSELLIN (1,2), Vincent JANIAK (3,4), Vincent BONNY (1,2), Come BUREAU (1,2), Julien MAYAUX (1), Elise MORAWIEC (1), Gwendoline TALLEC (4), Umar SALEEM (4), Andrea PINNA (3), Martin DRES (1,2)
(1) AP-HP. Sorbonne Université, Hôpital Pitié-Salpêtrière, Service de Médecine Intensive – Réanimation (Département \"R3S\"), Paris, FRANCE ; (2) Sorbonne Université, INSERM, UMRS1158 Neurophysiologie respiratoire expérimentale et clinique, Paris, FRANCE ; (3) Sorbonne Université, CNRS, LIP6, Paris, FRANCE ; (4) Bioserenity, Paris, FRANCE","contentIntroduction":"Chest Electrical Impedance Tomography (EIT) is a non-invasive technique that produces continuous cross-sectional images of regional lung ventilation. Tidal impedance variation has been recently proposed to estimate the tidal volume of patients with acute respiratory failure by using a calibration factor given by the ratio of tidal volume divided by tidal impedance variation1. Whether this calibration factor can be used in all patients is unknown. This study hypothesized that K-factor varies between patients.","contentPatientsMethods":"We took the opportunity of a study evaluating chest electrical impedance tomography in mechanically ventilated patients. EIT was connected to the ventilator and a 5-minute recording was performed while patients were still under pressure support. Median chest impedance variation and median tidal volume were calculated through 100 respiratory cycles over the 5 minutes period for each patient (or less if respiratory rate was below 20 per minute). K-factor was calculated by dividing median tidal volume by median chest impedance variation and was then expressed in mL/arbitrary units.","contentResultats":"Thirty-four patients were included, but only twenty-six had full EIT and ventilator data available. The median K-factor was 0.16 mL/UA (IQR 0.14 – 0.23 mL/UA) (Figure 1). After applicating a Pearson correlation, factors associated with K-factor were height (r2 = 0.15, p = 0.04), weight (r2 = 0.50, p < 0.01), level of PEEP (r2 = 0.40, p < 0.01) and hematocrit (r2 = 0.30, p < 0.01).","contentDiscussion":"","contentConclusion":"K-factor largely varies among patients and a single value cannot accurately estimate the tidal volume. K-factor was correlated with other variables than chest impedance variation alone.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1. Mauri T, Turrini C, Eronia N, et al. Physiologic Effects of High-Flow Nasal Cannula in Acute Hypoxemic Respiratory Failure. Am J Respir Crit Care Med. 2017;195(9):1207-1215.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"JOUSSELLIN Vincent"},{"id":99412,"num":"A34519CS","reference":"FC-078","title":"Effects of Almitrine administration as rescue therapy in spontaneously breathing patients with severe pneumonia related to SARS-COV-2 treated with high-flow nasal canula oxygen therapy","formatedAuthors":"Clément SACCHERI (1), Lucas MORAND (1), Denis DOYEN (1), Hervé HYVERNAT (1), Romain LOMBARDI (1), Raphaël DEVANLAY (1), Emilie PANICUCCI (1), Jean DELLAMONICA (1), Mathieu JOZWIAK (1)
(1) CHU de Nice, Nice, FRANCE","contentIntroduction":"Hypoxemia in SARS-COV-2 pneumonia results from abnormal ventilation/perfusion ratio related to blunted hypoxic vasoconstriction. Almitrine is a selective pulmonary vasoconstrictor that has been reported to improve the oxygenation in mechanically ventilated patients with acute respiratory distress syndrome related to SARS-COV-2 pneumonia, but its effects in spontaneously breathing patients treated with high-flow nasal canula oxygen therapy (HFNO) as first-line ventilatory support remain to be determined.","contentPatientsMethods":"In this single-center, observational and physiological study, a bolus of Almitrine was administered (0.5mg/kg over 30 minutes) as rescue therapy in spontaneously breathing patients with severe pneumonia related to SARS-COV-2 treated with HFNO and with persistent severe hypoxemia (PaO2/FiO2 ratio<100 with FiO2>80%) after awake prone positioning failure. Arterial blood gases and transthoracic echocardiography were performed just before and after the Almitrine bolus. Almitrine responder was definied by an increase in PaO2/FiO2 ratio >20%, that was analyzed in light of thoracic CT-Scan patterns (acute fibrinous and organizing pneumonia (AFOP); diffuse alveolar damage (DAD); bi-basal dependent areas of consolidation) obtained at hospital or ICU admission.","contentResultats":"Overall 62 patients were included (34% of female, 60±11 years old). No patient experienced right ventricular dysfunction or acute core pulmonale after Almitrine administration. Almitrine increased the PaO2/FiO2 ratio from 68(61-79) to 109(85-156) (p<0.001) and 46 (74%) patients were responders. Almitrine also decreased the PaCO2 (33 vs. 31mmHg, p<0.001) while the respiratory rate remained unchanged (27 vs. 28 cycles/min, p=0.45). The CT-Scan patterns distribution was : AFOP in 36 (58%) patients, DAD in 20 (32%), patients and bi-basal dependent areas of consolidation in 6 (10%) patients. The proportion of Almitrine responders was similar across the different CT-Scan patterns (75% for AFOP, 70% for DAD and 83% for bi-basal dependent areas of consolidation, respectively). The responders had a lower intubation rate (33 vs. 88%, p<0.001) and shorter ICU length of stay (5(3-9) vs. 10(6-17), p<0.01) than non-responder patients.","contentDiscussion":"","contentConclusion":"Almitrine iv administration as a rescue therapy in severe COVID-19 pneumonia under HFNO improved oxygenation in responders with a decreased rate of intubation rate. Patterns of the thoracic CT-Scan performed on hospital or ICU admission did not help to predict the response to Almitrine in terms of oxygenation. Further clinical trials are needed to confirm these results.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SACCHERI Clément"},{"id":99413,"num":"A34356LL","reference":"FC-079","title":"The use of inhaled Nitric Oxide (iNO) in Covid19 ARDS patients : A French retrospective registry.","formatedAuthors":"Armand MEKONTSO DESSAP (2), Laurent PAPAZIAN (3), Manuella SCHALLER (14), Saadalla NSEIR (12), Bruno MEGARBANE (5), Luc HAUDEBOURG (6), Jean-François TIMSIT (7), Jean-Louis TEBOUL (8), Khaldoun KUTEIFAN (9), Marc GAINNIER (10), Michel SLAMA (11), Juan Fernando RAMIREZ (14), Patrick HOUETO (14), Laurent LECOURT (13), Alain MERCAT (4), Antoine VIEILLARD BARON (1)
(1) CH Ambroise Paré (AP-HP), Boulogne Billancourt, FRANCE ; (2) CHU de Créteil_Henri Mondor (AP-HP) , Creteil, FRANCE ; (3) CHU MARSEILLE (APHM ), Marseille , FRANCE ; (4) CHU d'ANGERS, Angers, FRANCE ; (5) CH LARIBOISIERE (AP-HP), Paris, FRANCE ; (6) CH Pitié Salpêtrière (AP-HP) , Paris , FRANCE ; (7) CH BICHAT (AP-HP), Paris , FRANCE ; (8) CH BICETRE (AP-HP), Paris , FRANCE ; (9) CH de MULHOUSE, Mulhouse, FRANCE ; (10) Hôpital La Timone (APHM), Marseille , FRANCE ; (11) CHU Amiens, Amiens, FRANCE ; (12) CHU Lille , Lille , FRANCE ; (13) Air Liquide Healthcare , Gentilly , FRANCE ; (14) Air Liquide Healthcare , Les Loges Josas, FRANCE","contentIntroduction":"Inhaled Nitric Oxide (iNO) has been widely used all over the world during COVID19 pandemia1. Previous studies reported conflicting results on the effect of iNO on oxygenation improvement. \n The objective of this registry was to describe the use of iNO in a large cohort of Covid19 ARDS (CARDS) patients.","contentPatientsMethods":"Multi-center, retrospective cohort registry conducted in 12 French hospitals during the first year of pandemia on CARDS patients treated with iNO. \n Patients characteristics, clinical respiratory support, nitric oxide therapy safety and efficacy parameters and patients clinical outcomes were collected. iNO response was defined as PaO2/FiO2 ratio improving by >= 20% after iNO initiation.","contentResultats":"From march to december 2020, 300 CARDS patients (22.3% female) were included in the registry. At ICU admission, their median (IQR) age, SAPS II, and SOFA scores were 66 (57-72) years, 37 (29 - 48), and 5 (3 - 8), respectively. \n Patients were still hypoxaemic despite protective ventilation (in all patients) and prone positioning sessions (in 68%). \n At iNO initiation, 2%, 37%, and 61% patients had mild, moderate, and severe ARDS, respectively. Median (IQR) delay between iNO therapy initiation and ICU admission, ARDS diagnosis, and intubation were 7 (3 - 12), 6 (2 - 11) and 4 (1 - 10) days respectively.\n The median duration of iNO was 2.8 (1.1 - 5.5) days with a median dosage of 10 (7 - 13) ppm at initiation. \n Responders were analyzed at different stages: 45.7% of patients were responders within 6h following iNO initiation, 56.9% based on the best PaO2/FiO2 ratio within 24 hours after iNO initiation and 70.3% patients had at least one response during iNO administration. \n The severity of ARDS is the only predictive factor associated with iNO response considering the best PaO2/FO2 ratio obtained within 24 hours (figure 1). \n This arterial oxygenation improvement did not impact the patients outcomes (length of ICU/hospital stay, ventilation duration, mortality) in the global population. \n Regarding safety aspects, renal replacement therapy was initiated in 23.5% patients during iNO administration, and 60.5% patients presented a Kdigo score I, II and III within 24 hours following iNO initiation, without a formal causal link with iNO.","contentDiscussion":"","contentConclusion":"This registry confirmed the benefits of iNO for arterial oxygenation improvement in severe ARDS patients still hypoxaemic after optimization of ventilation and prone positioning.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study Intensive Care Med. 2020 Oct 29 : 1–14.doi: 10.1007/s00134-020-06294-x PMCID: PMC7674575 PMID: 33211135","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MEKONTSO DESSAP Armand"},{"id":99414,"num":"A34612ME","reference":"FC-080","title":"Predicting the outcome of patients with acute respiratory distress syndrome using a miniature transesophageal ultrasound probe","formatedAuthors":"Mehdi EDDERKAOUI (1), Olivier POULY (1), Julien GOUTAY (1), Claire BOUREL (1), Thierry ONIMUS (1), Raphael FAVORY (1), Arthur DURAND (1), Sébastien PREAU (1)
(1) CHRU LILLE, Lille, FRANCE","contentIntroduction":"The objective of the study was to test whether sequential monitoring of the superior vena cava (SVC), by allowing measurement of the superior vena cava collapsibility index (SVCci), could be a prognostic marker in patients with acute respiratory distress syndrome (ARDS).","contentPatientsMethods":"50 patients admitted to 5 intensive care units (ICU) with moderate to severe ARDS and receiving invasive mechanical ventilation for less than 24 hours were prospectively included. The minimum (inspiratory) and maximum (expiratory) telediastolic diameter of the SVC were monitored every 8 hours using a miniature ClariTEETM transesophageal ultrasound probe (CLT0110-1, IMACOR, New York NY, USA) for up to 72 hours after inclusion. The SVCci was calculated as follows: (maximum diameter – minimum diameter) / maximum diameter. The primary outcome was 90-day mortality.","contentResultats":"In-hospital mortality censored at 28 and 90 days was of 30% (n=15) and 34% (n=17), respectively. The median (interquartile range) length of stay in the intensive care unit (ICU) was 14 days (8-23). The number of days alive without mechanical ventilation at 28 days was 17 (0-23). The mean SVCci measured over the first 24 hours after inclusion (SVCci-D1) was significantly higher in survivors compared to non-survivors at 90 days: 0.23 (0.16-0.31) versus 0.17 (0.14 0.21), p=0.048. The mean SVCci measured over the first 72 hours after inclusion (SVCci-D3) was significantly higher in survivors compared to non-survivors at 90 days: 0.22 (0.17-0.24) versus 0.17 (0.14-0.21), p=0.028. A SVCci-D1 <0.20 and a SVCci-D3 <0.22 predicted 90-day mortality with areas under ROC curve (±standard error of the mean) of 0.692 (±0.079) and 0.692 (±0.078), sensitivities of 64% and 58%, and specificities of 71% and 88%, respectively.","contentDiscussion":"","contentConclusion":"The mean SVCci measured over the first days after ICU admission, appears to be a prognostic marker of 90-day mortality in patients with moderate to severe ARDS.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"EDDERKAOUI Mehdi"},{"id":99415,"num":"A34240CG","reference":"FC-081","title":"Assessment of airway opening pressure with electrical impedance tomography in patients with acute respiratory distress syndrome","formatedAuthors":"Bruno LOUIS (2), Martin COUR (1), Laurent ARGAUD (1), Claude GUÉRIN (1)
(1) Hôpital Edouard Herriot Hospices Civils de Lyon, Lyon, France, FRANCE ; (2) Institut Mondor de Recherches Biomédicales, Créteil, FRANCE","contentIntroduction":"Airway opening pressure (AOP) determined in patients with acute respiratory distress syndrome (ARDS) from the inspection of volume-pressure curve (1) should mean that lung ventilation increases once AOP is overcome. To address this issue we compared AOP measured from both inspiratory volume-pressure curve and electrical impedance tomography (EIT) simultaneously recorded during low flow inflation of the respiratory system. If AOP reflects a critical opening pressure it should correlated with AOP measured with EIT (AOPEIT).","contentPatientsMethods":"In this secondary analysis of a previous study (2) 10 ARDS patients were investigated at positive end-expiratory pressure of 5, 10 and 15 cmH2O in the semi-recumbent position under continuous sedation and paralysis. Airway pressure (Paw) and flow signals were measured at the proximal tip of the endotracheal tube and sent to MP 150 datalogger (Biopac Inc.). Pulmovista EIT device (Drager) was used to assess lung ventilation. The respiratory system was inflated at a 7 L/min constant flow inflation delivered by the ventilator (Evita XL) and airway pressure, flow and EIT signals recorded simultaneously. AOP was defined as the pressure where the volume delivered to the patient was 4 ml greater than the volume delivered to the occluded circuit (1). AOPEIT was estimated during low insufflation from Paw-EIT-derived Volume curves fitted by a sigmoidal equation. When the lower inflexion point was below PEEP, AOPEIT was considered equal to PEEP. The values of AOP and AOPEIT were analysed by using the rho Spearman correlation coefficient and the Bland and Altman representation over 30 pairs. P<0.05 was set as the statistically significant threshold.","contentResultats":"AOP and AOPEIT were significantly correlated (Spearman rho = 0.73, P =0.000005). The mean bias was 0.44 cmH2O. In 96% (29/30) of the cases the differences observed between the two methods were less than 2 cmH2O.","contentDiscussion":"","contentConclusion":"AOP and AOPEIT are significantly correlated.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1) Chen et al AJRCCM 2018","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"(2) Guérin et al J Appl Physiol 2020","presentateur":"LOUIS Bruno"},{"id":99416,"num":"A34494ml","reference":"FC-082","title":"Pattern of FRC variation following prone positioning in Covid-ARDS: Evaluation by the nitrogen washin-washout method.","formatedAuthors":"Manel LAHMAR (1), Abir CHIHAOUI (1), Hedia BEN AHMED (1), Zeineb HAMMOUDA (1), Oussema SAADAOUI (1), Fahmi DACHRAOUI (1), Fekri ABROUG (1), Lamia BESBES OUANNES (1)
(1) CHU fattouma bourguiba Monastir , Monastir, TUNISIE","contentIntroduction":"Acute Respiratory Distress Syndrome (ARDS) is characterized by reduction of all lung volumes (in particular that of FRC), and a decrease in respiratory system compliance (Crs). Prone positioning which is recommended in severe ARDS allows a more uniform distribution of the ventilation/perfusion ratios with alteration in Crs properties resulting in lung recruitment, FRC increase, and improvement of oxygenation and survival. The alveolar recruitment process is time-dependent with uncertainty about the optimal daily prone duration.The aim of our study is to characterize the pattern of FRC increase (kinetic and magnitude) during the first 24 hours following prone positioning in patients with Covid-19 related ARDS (C-ARDS).","contentPatientsMethods":"a prospective observational study conducted between January and October 2021, including consecutive patients admitted to the ICU for severe C-ARDS (PaO2/FiO2 ≤150 mm Hg) and requiring tracheal intubation and mechanical ventilation. Patients were ventilated in supine position with a lung protective strategy (Vt≤6ml/Kg of IBW, the highest PEEP level to obtain a plateau pressure≤30 cm H2O). Patients were systematically turned prone and FRC was measured immediately after prone position and every 2 hours during the first 24 hours. The measurements were carried out using the Nitrogen Wash-in Wash-out technique available on the CARESCAPE R860 respirator (General Electrics, Wisconsin, USA). The usual oxygenation (SaO2/FiO2) and ventilatory mechanics (Csr, and strain) variables were also recorded.","contentResultats":"20 patients (14 men, mean age: 65± 9 years, PaO2/FiO2: 105± 42, mean static compliance: 28.5± 5, mean PEEP: 14± 2) were included in the study.","contentDiscussion":"","contentConclusion":"Prone positioning evokes a rapid and progressive improvement in FRC and oxygenation. These effects are associated with improved strain on the lungs","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAHMAR Manel"},{"id":99417,"num":"A34749BP","reference":"FC-083","title":"Regional airway closure and patients positioning in acute hypoxemic respiratory failure","formatedAuthors":"Bertrand PAVLOVSKY (1), Pierre LEPROVOST (1), Arnaud LESIMPLE (1), Christophe DESPREZ (1), Mathilde TAILLANTOU-CANDAU (1), Jean-Christophe RICHARD (1), Alain MERCAT (1), François BELONCLE (1)
(1) CHU Angers, Angers, FRANCE","contentIntroduction":"Airway closure leading to an interruption of ventilation in the downstream alveoli may be associated with ventilation inhomogeneity and ventilation-induced lung injury. This phenomenon may be detected at the bedside by performing a low-flow insufflation pressure-volume or pressure-time curve. Airway opening may vary across the lung. We aimed to study the regional distribution of airway opening in semi-recumbent and strict supine position in a series of patients with acute hypoxemic respiratory failure (AHRF).","contentPatientsMethods":"Twenty patients admitted to a Medical ICU and intubated for AHRF (PaO2/FiO2 ratio <300 mmHg) were enrolled within the 12 first hours after intubation. Patients were ventilated in volume-controlled ventilation (tidal volume 6mL.kg-1 predicted body weight PBW) and a positive end-expiratory pressure of 5 cmH2O and positioned (1) in the semi-recumbent position (head of bed at 30°) and (2) in the strict supine position (0°). Measurements of end-expiratory lung volume (EELV) using the nitrogen wash-out wash-in technique and reported to PBW, respiratory mechanics, gas distribution using electrical impedance tomography and a low-flow insufflation to detect airway closure were performed after 30 minutes in each position. One global (obtained with the volume changes measured by the ventilator at the airway opening) and two regional (using regional impedance waveforms to estimate the non-dependent and dependent real-time volume changes) pressure-volume curves were constructed offline using a dedicated software.","contentResultats":"Age was 63 [52-71]. PaO2/FiO2 ratio was 240 [140-287] mmHg, and respiratory system compliance (CRS) was 52 [46-59] mL.cmH2O-1. Twelve patients fulfilled acute respiratory distress syndrome (ARDS) criteria.\n An airway closure was detected on the airway pressure-volume curve in 3 patients (15%). A regional airway closure was observed in the dependent regions in 6 patients (30%). No difference in PaO2/FiO2 (240 [157-317] vs 227 [135-295], p>.999) nor CRS (51 [41-57] vs 53 [47-61] mL.cmH2O-1, p>0.999) was observed between patients with or without regional airway closure. But EELV/PBW was lower in patients with regional airway closure (16 [15-17] vs 28 [23-34] mL.kg-1 PBW, p<0.001). Supine position was associated with a decrease in EELV/PBW (25 [18-33] vs 21 [16-34] mL.kg-1, p=0.009) and an increase (albeit non significant) in regional airway closure prevalence (45% vs 30%, p=0.515).","contentDiscussion":"","contentConclusion":"In patients with AHRF, airway closure seems frequent in dependent regions, in particular in strict supine position.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1199","session":"FLASH COM - COVID-19 : actualités physiologiques dans l'insuffisance respiratoire aiguë","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PAVLOVSKY Bertrand"},{"id":99418,"num":"A34554LG","reference":"FC-084","title":"Corticosteroid for acute exacerbations of COPD in ICU. A French Cohort: OUTCOMEREA database.","formatedAuthors":"Louis-Marie GALERNEAU (1,2), Sébastien BAILLY (2), Nicolas TERZI (1), Stéphane RUCKLY (3), Maité GARROUSTE-ORGEAS (4), Yves COHEN (5), Vivien HONG TUAN HA (6), Marc GAINNIER (7), Shidasp SIAMI (8), Claire DUPUIS (9), Michael DARMON (10), Elie AZOULAY (10), Jean-Marie FOREL (11), Florian SIGAUD (1), Christophe ADRIE (12), Dany GOLDGRAN-TOLEDANO (13), Fabrice BRUNEEL (14), Etienne DE MONTMOLLIN (15), Laurent ARGAUD (16), Jean REIGNIER (17), Jean-Louis PEPIN (1,2), Jean-François TIMSIT (15)
(1) CHU Grenoble Alpes, La Tronche, FRANCE ; (2) Université Grenoble Alpes, INSERM U1300 HP2, , Grenoble, FRANCE ; (3) Département de biostatistiques, Outcomerea, Paris, FRANCE ; (4) Hôpital Franco-Britannique, Levallois-Perret, FRANCE ; (5) AP-HP, Hôpital Avicenne, Paris, FRANCE ; (6) Grand Hôpital de l'Est Francilien, Meaux, FRANCE ; (7) Hôpital de ta Timone, Marseille, FRANCE ; (8) Centre Hospitalier Sud Essonne, Étampes, FRANCE ; (9) CHU Gabriel-Montpied, , Clermont-Ferrand, FRANCE ; (10) AP-HP, Hôpital Saint-Louis, Paris, FRANCE ; (11) Hôpital Universitaire Marseille Nord, Marseille, FRANCE ; (12) Hôpital Delafontaine Hôpital, Saint-Denis, FRANCE ; (13) Groupe Hospitalier Intercommunal Le Raincy Montfermeil, Montfermeil, FRANCE ; (14) Centre Hospitalier de Versailles, Le Chesnay, FRANCE ; (15) AP-HP, Hôpital Bichat, Paris, FRANCE ; (16) Hospices civils de Lyon, Hôpital Edouard Herriot, Lyon, FRANCE ; (17) CHU de Nantes, Nantes, FRANCE","contentIntroduction":"Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a very frequent in intensive care unit (ICU). However, there are few data and conflicting results about corticosteroids therapy for critically ill patients with an AECOPD.","contentPatientsMethods":"In this study, using data from the observational longitudinal cohort OutcomeReaTM database, with 32 french ICU centres participating, we assessed the impact of corticosteroid therapy for patients in ICU for an AECOPD.\n The prescription of corticosteroids therapy at admission was defined as a daily dose ≥ 0.5 mg/kg of prednisone during the first 24 hours after admission in ICU. We assessed the effect of corticosteroids on a main composite criteria including death and invasive mechanical ventilation (IMV) at day 28 after admission in ICU using an inverse probability of treatment weight (IPTW) estimator. Secondary outcomes were: survival analyse at D-28 and D-90, NVI failure, length of stay in ICU and in hospital, duration of ventilation, consumption of antibiotics and adverse effects of corticosteroids.","contentResultats":"We included 1,247 patients of which 31,4% was treated by a corticosteroid therapy at admission.\n Corticosteroids administration at admission was significantly found as protector on the main composite outcome (RR = 0.693 [0.489; 0.98], p=0.038). For the subgroup of patients with a very severe COPD, the protective effect of corticosteroid therapy on the primary composite outcome was not found (RR = 1,205 [0.577; 2.517], p=0.6203).\n There was no significant impact of corticosteroids on failures of NIV, on lengths of stay in ICU and in hospital or on durations of ventilation. \n We did not observe statistical relation between the corticosteroid prescription at global prescription of antibiotics. However, corticosteroid therapy tended to be associated with longer duration of antibiotics treatment for patients in ICU at least 10 days (effect of corticosteroid therapy on antibiotic-free days at 10-day for the 395 patients with a length of stay in ICU ≥ 10 days : IRR = 0. 776[0.597; 1.009], p=0.059)).\n Nosocomial infectious had the same prevalence in the two groups of patients. But the maximum systolic blood pressure and the levels of urea was higher and the glycemic disorders more frequent when patient received corticosteroids.","contentDiscussion":"","contentConclusion":"A corticosteroids administration at admission in ICU to patients with AECOPD had a protective effect on death or invasive mechanical ventilation at Day 28. Studies on doses to use or the profile of patients to treat are needed.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GALERNEAU Louis-Marie"},{"id":99419,"num":"A34458BP","reference":"FC-085","title":"Use of high-flow oxygen nasal cannula oxygenation in adult patients with sickle cell disease admitted in ICU: a pilot study.","formatedAuthors":"Bertrand PONS (1), Antoine BERTHOD (1), Michel CARLES (2), Frédéric MARTINO (1)
(1) CHU Guadeloupe, Les Abymes, GUADELOUPE ; (2) CHU NICE, Nice, FRANCE","contentIntroduction":"Sickle cell disease (SCD) is a life-threatening genetic disorder associated with many chronic and acute complications [1]. Oxygen therapy is one of the cornerstone of management of patients with SCD admitted to hospital. Recently, high flow nasal cannula (HFNC) oxygenation has emerged, and clinical practice guidelines have been released for the use of HFNC in the overall population [2]. But at this very time, no evidence have been reported of the use of HFNC in patients with SCD. The objective of this pilot study was to evaluate the efficacy and tolerance of HFNC in comparison of conventional oxygen therapy via facial mask (FM) in adult patients with SCD admitted in ICU.","contentPatientsMethods":"Consecutive adult patients with SCD (SS, SC, or SBeta thalassemia) admitted in ICU with clinical symptoms compatible with ACS were eligible. Early-stage ACS and management of all patients included was defined accordingly to the actual national French guidelines. Randomization defined the initial oxygen therapy during a 4 session course of 5-hour oxygen therapy with, alternately, HFNC (FiO2 60%, flow rate 60 L/min) and FM (FiO2 60%, flow rate 15 L/min). Blood samples were analyzed at the beginning and end of each session. Comfort, dyspnea, and tolerance were assessed at multiple predefined times during the study. Accordingly to the French law, written informed consent was obtained from all patients prior to enrollment.","contentResultats":"Seven patients were included and 24 sessions of oxygen therapy have been completed. There was no significant difference in clinical and biological variables between the beginning (H0) and the end (H5) of oxygen therapy session (Tab 1). Median PaO2 throughout the session was higher with HFNC (49 [23, 85] mmHg) compared to FM (18 [-26, 30] mmHg, p=0.04). Incidence of episodes of desaturation was greater in HFNC vs FM (4 episodes (33%) vs 1 (8%) respectively, p=0.04) without any episode of severe desaturation (SpO2 < 90%). Comfort was statistically non different between the 2 techniques (9.4 [7-10] under FM vs 8.3 [4.7-9.4] under HFNC, p=0.31).","contentDiscussion":"In our study, HFNC was associated with a greater benefit in term of oxygenation compared to conventional oxygen therapy. Despite the limitations of this study, our results suggest a potential benefit of HFNC use, in term of oxygenation, in SCD patients with acute respiratory failure.","contentConclusion":"In adult patients with SCD admitted in ICU for acute respiratory failure, HFNC could be of interest to improve oxygenation, compared to conventional oxygen therapy.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1. Yawn BP, Buchanan GR, Afenyi-Annan AN, et al: Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members [published correction appears in JAMA 2014; 312(18):1932] [published correction appears in JAMA 2015 Feb]","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"4. Rochwerg B, Einav S, Chaudhuri D, et al: The role for high flow nasal cannula as a respiratory support strategy in adults: A clinical practice guideline. Intensive Care Med 2020; 46(12):2226-2237.","presentateur":"PONS Bertrand"},{"id":99420,"num":"A34459LG","reference":"FC-086","title":"Long-term exposure to ambient air pollution is associated with an increased incidence and mortality of acute respiratory distress syndrome in a large French region.","formatedAuthors":"Laetitia GUTMAN (1,2), Vanessa PAULY (2), Veronica ORLEANS (2), Damien PIGA (3), Yann CHANNAC (3), Alexandre ARMENGAUD (3), Laurent BOYER (2), Laurent PAPAZIAN (1,2)
(1) Assistance publique des hopitaux de marseille - Hôpital nord, Marseille, FRANCE ; (2) Faculté de sciences médicales et paramédicales Aix marseille, Marseille, FRANCE ; (3) ATMOSUD, Marseille, FRANCE","contentIntroduction":"Air pollution exposure is suspected to alter both the incidence and mortality in acute respiratory distress syndrome (ARDS). The impact of chronic air pollutant exposure on the incidence and mortality of ARDS from various aetiologies in Europe remains unknown. The main objective of this study was to evaluate the incidence of ARDS in a large European region, 90-day mortality being the main secondary outcome.","contentPatientsMethods":"The study was undertaken in the Provence-Alpes-Cote-d’Azur (PACA) region. Nitrogen dioxide (NO2), particulate matter (PM2.5 and PM10) and ozone (O3) were measured. The Programme de Médicalisation des Systèmes d’Information (PMSI), which captures all patient hospital stays in France, was used to identify adults coded as ARDS.","contentResultats":"From 2016 to 2018, 4,733 adults with ARDS treated in intensive care units were analysed. The incidence rate ratios for 1-year average exposure to PM2.5 and PM10 were 1.207 ([95% confidence interval (95% CI), 1.145-1.390]; P<0.01) and 1.168 (95% CI, 1.083-1.259; P<0.001), respectively. The same trend was observed for both 2- and 3-year exposures, while only chronic 1- and 2-year exposure NO2 exposures were related to a higher incidence of ARDS. Increased PM2.5 exposure was associated with a higher 90-day mortality for both 1- and 3-year exposures (OR 1.096 (95% CI, 1.001–1.201) and 1.078 (95% CI, 1.009-1.152), respectively). O3 was not associated with either of incidence or mortality.","contentDiscussion":"","contentConclusion":"Increased exposures to NO2, PM2.5 and PM10 were associated with an increased incidence of ARDS. Increased exposure to PM2.5 was also associated with increased 90-day ARDS mortality.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PAPAZIAN Laurent"},{"id":99421,"num":"A34550JH","reference":"FC-087","title":"Clinical practice survey: assessment and ventilatory management of sickle cell patients in intensive care","formatedAuthors":"Julien HAGRY (1), Armand MEKONTSO-DESSAP (2), Xavier MONNET (1), Keyvan RAZAZI (2), Christelle CHANTALAT (1), Nicolas DE PROST (2), Tài PHAM (1)
(1) CHU Bicêtre, Le Kremlin-Bicêtre, FRANCE ; (2) CHU Henri Mondor, Créteil, FRANCE","contentIntroduction":"Sickle cell disease, a common genetic disease in France, is a haemoglobinopathy characterised by a β-globin abnormality and the production of haemoglobin S. Hyperalgesic vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) are the main complications leading to intensive care units (ICU) admissions. Despite frequent hospitalizations in ICUs, there is heterogeneity in treatment and global management due to a lack of ICU-specific guidelines. We aimed at gathering the medical practices of ICUs nationwide.","contentPatientsMethods":"We carried out an online survey that was sent to medical teams of all ICUs of French hospitals identified as expert centers in the Orphanet database (https://www.orpha.net). Physicians from the same unit sent consensus answers to capture the usual care in their ICU, providing one survey answer per unit. The survey included sections related to: demography; usual pain management, and three clinical situations (hyperalgesic VOC, VOC with chest pain, and ACS with chest pain, dyspnea and fever).","contentResultats":"Of 55 centers contacted, 29 (53%) answered the survey, including 18 (62%) university-hospitals, 10 (34.5%) general hospital centers and 1 (3.5%) private hospital. The median [IQR] number of ICU beds was 23 [18-28]. We grouped centers according to the annual number of admissions: 16 (55%) centers admitted less than 10 patients with sickle cell disease per year. Pain management: nitrogen monoxide-oxygen mixture was used in 72% of centers. Nonsteroidal anti-inflammatory drugs were more likely used by centers admitting more than 10 patients per year, though not achieving statistically difference (61.5% vs 25%, p=0.108). Oxygenation and physiotherapy: conventional oxygen therapy was decided regardless of the oxygen saturation in 52% for VOC and 55% in VOC associated with chest pain or ACS). Physiotherapy and incentive spirometry was systematically prescribed in 69% of the centers during a VOC, 82% in case of VOC with chest pain and 62% during ACS. Ventilatory support: according to physicians, non-invasive ventilation main benefit during ACS was the effect on alveolar recruitment and hypercapnia (90%), but patients’ tolerance seems to be its main limitation for 69%. High-flow nasal oxygen (HFNO) was considered easy to use (86%) and well-tolerated by patients (83%), but to 76% of the responders, its efficacy during ACS needs to be proven by large studies.","contentDiscussion":"","contentConclusion":"Pain and respiratory management of patients with sickle cell disease acute complications seems to be heterogeneous amongst expert centers. Incentive spirometry to treat or prevent ACS needs to be generalised. Further studies evaluating the benefits of HFNO are needed.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HAGRY Julien"},{"id":99422,"num":"A34497FB","reference":"FC-088","title":"Acute exacerbations in chronic obstructive pulmonary diseases: eosinophil-guided corticosteroid therapy versus standard care","formatedAuthors":"Feriel BEN ABA (1), Rim GHARBI (2), Zeineb HAMMOUDA (1), Manel LAHMAR (1), Habiba SIKALI (2), Mohamed FEKIH HASSEN (2), Lamia BESBES (1), Souheil ELATROUS (2), Fekri ABROUG (1)
(1) Service de réanimation polyvalente CHU Fattouma Bourguiba, Monastir, TUNISIE ; (2) Service de réanimation médicale CHU Tahar Sfar, Mahdia, TUNISIE","contentIntroduction":"Administration of systemic corticosteroid (SC) in acute exacerbations of chronic obstructive pulmonary diseases (AECOPD) patients requiring mechanical ventilation (VM) is controversial. There are biomarkers such as plasmatic eosinophilia (PE) that could predict a beneficial response to SC. The aim of our study was to assess whether a strategy of CS administration based on PE level was not inferior to the standard strategy consisting in systematic administration of CS regardless of the severity.","contentPatientsMethods":"In a bi-centric, prospective, randomized, controlled, and single-blind trial conducted between December 2018 and December 2020, eligible patients over 18 years of age, hospitalized for an AECOPD and requiring ventilatory support (n=43) were included and randomized to usual care (n=25) or eosinophil-guided strategy (n=18). The prescription of SC in the eosinophil-guided group was based on PE (1mg/kg of prednisone if PE >2%; no SC if PE ≤ 2%). The primary end- point was whether patients still needed MV in the sixth day or not.","contentResultats":"There was no between-group difference for demographics, COPD and acute episode characteristics.\n Regarding the primary end-point, there was no difference for the type of ventilation modality in the sixth day following the inclusion (Still on MV: 32% versus 39% in the standard group and the eosinophilic group, respectively). A difference of 7% that is less than the 10% which confirm the non-inferiority hypothesis.\n The relative risk to be still on MV by the 6th day was 1.2 (IC 95%: 0.54-2.7) p=0.640, reaching the prior fixed non difference margin. Both study groups showed similar secondary outcomes: Treatment failure (p=0.712), MV duration (p=0.620), length of stay (p=0.429) and mortality (p=0.701). Hyperglycemic episodes due to SC occurred more frequently in the control group (6 cases versus 2) but no statistical significance was found (p=0.434).","contentDiscussion":"","contentConclusion":"This preliminary study confirms the similarity between a CS sparing strategy based on PE count and the standard systematic administration of CS.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BEN ABA Feriel"},{"id":99423,"num":"A34707zH","reference":"FC-089","title":"EFFECT OF BETA-BLOCKERS PRESCRIPTION ON THE OUTCOME OF SEVERE ACUTE EXACERBATION OF CHRONC OBSTRUCTIVE PULMONARY DISEASE (AECOPD) REQUIRING ICU ADMISSION.","formatedAuthors":"Zeineb HAMMOUDA (1), Maroua BOUATTIA (1), Emir BEDHIAFI (1), Iyed MAATOUK (1), Fadoua HOURI (1), Manel LAHMAR (1), Fahmi DACHRAOUI (1), Fekri ABROUG (1), Lamia BESBES OUANES (1)
(1) CHU Fattouma Bourguiba MONASTIR, Monastir, TUNISIE","contentIntroduction":"Cardiovascular diseases are frequent comorbidities in patients with COPD and are conditions with large use of beta-blockers (BB). We aimed to evaluate the influence of BB prescription on AECOPD outcome.","contentPatientsMethods":"This is a single-centre retrospective study conducted in a 16-bed ICU of Fattouma-Bourguiba University-hospital. From January 2016 to June 2019, all consecutive patients admitted for an AECOPD and aged≥18 years were included. Exclusion criteria were: AECOPD requiring specific treatment and unavailable long-term follow-up.\n Patients were divided on 2 groups: (BB+) previously receiving Beta-blockers or requiring Beta-blockers agents upon their admission and (BB-) who did not receive beta-blockers neither previously nor during ICU stay. Data were collected on socio-demographic characteristics, past historyand COPD GOLD stage, clinical presentation and labs findings. Severity was assessed using SAPS II and ABG’s parameters. We also recorded details of ICU course. Follow-up data included mortality at 6 months of ICU discharge and life quality assessment using the Clinical COPD Questionnaire (CCQ).","contentResultats":"220 patients were included. Median age was 68(IQR: 61-75), 88.2% were male with a BMI at 26.12(23.6–30.1). Main comorbidities were hypertension 83(37.7%), chronic heart disease 60(27.3%) and diabetes 40(18.2%). Median SAPS II was 45(40-53). Main exacerbation causes were acute left heart failure in 99(45%) followed by tracheobrochitis 75(34.1%). NIV was the first-line ventilatory treatment in 88.2% with a failure rate at 26.8%. Median LOS was 16(IQR 10-27) days with a survival rate at 80.5%.\n 62(28.2%) were assigned to BB+ group versus 158 (71.8%) to BB-. Bisoprolol was the most used molecule (96.8%) with a median posology of 2.5(2.5-5)mg. 15(24.2%) patients were previously receiving BB, indications for BB upon admission were hypertension 39(62.5%) followed by left heart failure and tachycardia. Comparing the two groups, no major differences in severity assessment, ventilatory management or NIV failure were found. BB+ were older [73(65-78) versus 67(60-73.5), p=0.001] with higher BMI [27.7(24.7-31.2) versus 24.9(22-30), p=0.02] without difference in GOLD staging or long-term NIV requirement (p=0.4). BB- had lower LOS 15(9.7-23) versus 20.5(12.7-30.2) p= 0.004 with similar rates of ICU complications and mortality. Thus, 6 months mortality was significantly higher in BB- (34.2 versus 17.7%, p=0.016) [Figure1], and recurrence of AECOPD at one-year was lower in BB+ (43.5% versus 58.2%; p=0.04). No significant difference in CCQ assessment was found (p=0.2).","contentDiscussion":"","contentConclusion":"Despite similarities in ICU evolution, patients under beta-blockers appears to have better log-term outcome after AECOPD. Further studies might be needed to confirm this results.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HAMMOUDA Zeineb"},{"id":99424,"num":"A34369VL","reference":"FC-090","title":"Impact of intubation on the evolution of fractions of inspired oxygen in patients treated with high flow oxygen therapy for COVID-19 associated pneumonia","formatedAuthors":"Valentin LAFAY (1), Hadrien WINISZEWSKI (1), Alicia GUILLIEN (2), Gilles CAPELLIER (1)
(1) CHU de BESANCON, service de Réanimation Médicale, Besancon, FRANCE ; (2) Institut pour l’avancée des biosciences, Equipe d’épidémiologie environnementale appliquée au développement et à la santé respiratoire, Grenoble, FRANCE","contentIntroduction":"Since second wave, High Flow Oxygen Therapy (HFOT) is a first line treatment for COVID-19 associated respiratory failure.\n However, patients treated with HFOT may be exposed for a long time to high Fractions of Inspired Oxygen (FiO2), potentially leading to hyperoxic alveolar injuries.\n We aimed to determine whether intubating patients after HFOT failure was associated with a decrease in high FiO2 exposure within the 24 first hours following intubation.","contentPatientsMethods":"Among 218 patients admitted for COVID-19 associated pneumonia in Medical Intensive Care Unit (ICU) at Besançon teaching hospital between October 2020 and October 2021, 27 treated with HFOT for more than 24 hours before intubation were retrospectively included.\n The number of hours exposed to FiO2 > 60% and > 90% during the 24h preceding intubation and the 24h following intubation were calculated and compared.","contentResultats":"Most of the 27 patients were men, with a median age of 71 years-old. Twenty-one patients performed awake prone positioning (PP) under HFOT. The median PaO2/FiO2 was 79 mmHg before intubation, and 193 mmHg 24h after protective ventilation using a median Positive End-Expiratory Pressure (PEEP) of 12 cmH2O. The median dynamic compliance of the respiratory system was 40 cmH2O. All ventilated patients benefited from neuromuscular blockade and PP. Seven (26%) died in ICU.\n The median number of hours with FiO2 > 60% decreased from 22,5 (Interquartile range – IQR – [20,0 ; 24,0]) within the 24h under HFOT preceding intubation to 6,0 [4,0 ; 9,8] within the 24h following intubation, corresponding to a median difference of -15,0 [-18,0 ; -8,8], statistically significant (p<0,001).\n The median number of hours with FiO2 > 90% decreased from 3,0 [1,3 ; 15,5] to 2,0 [1,3 ; 3,0], corresponding to a median difference of -2,0 [-10,0 ; 0,], statistically significant (p=0,005).","contentDiscussion":"Intubation itself likely doesn’t explain the decrease in FiO2. High PEEP, neuromuscular blockade, and prone positioning are confounding factors. FiO2 is also dependant from the target of oxygenation set as a goal.\n To the best of our knowledge, this study is nevertheless the first caring about this pragmatic issue. Its main limitations are a retrospective and monocentric design, and a small sample size.","contentConclusion":"In COVID-19 patients treated with high flow oxygen therapy > 24h, intubation is associated with a statistically significant decrease in high FiO2 exposure.\n Whether intubation could decrease hyperoxic alveolar injury need to be investigated.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1200","session":"FLASH COM - Insuffisance respiratoire aiguë : une session sans COVID","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAFAY Valentin"},{"id":99425,"num":"A34761OH","reference":"FC-091","title":"Importance of Monitoring Ventricular Assisted Patients' Antithrombotic Treatment","formatedAuthors":"Omar HANAFIA (1), Julie PRIEUR-GARROUSTE (1), Pierre BERTAULT-PERES (1), Stéphane HONORE (1), Fabrice MICHEL (1)
(1) Hopitaux Universitaires de Marseille, Marseille, FRANCE","contentIntroduction":"We looked at a long-term external ventricular assist device (VAD), it’s a mechanical, pulsatile heart support system. It is indicated for patients with severe heart failure waiting for transplantation or recovery of their ventricular function. VAD imposes a stable and effective antithrombotic strategy. In pediatric resuscitation patients, inter- and intra-individual pharmacokinetic variability makes the use of these treatments with hemorrhagic and ischemic risks difficult. We conducted an evaluation of the professional practices of this strategy within the hospital’s pediatric resuscitation unit.","contentPatientsMethods":"Our monocentric, retrospective study included a population of VAD-implanted patients from December 2017 to January 2020. Clinical data was collected from the computerized patient record. The prescriptions for anticoagulants and antithrombotics were followed on the shipboard prescription. The results of the aggregation tests and the anti Xa assays were recorded on the laboratory software.","contentResultats":"Of the 36 months of the study: 5 middle-aged patients 12 months (sd=7.9) were implanted with a left mono VAD. 4 patients had dilated cardiomyopathy and one had cardiogenic shock. We had 14 serious vascular incidents of which 4 were hemorrhagic and 10 ischemic. The frequency of tests does not exclude accidents and 67% of them had clinical repercussions. AntiXa measurements were 53% (n=352) in the targets, the arachidonic acid test was effective in 58% (n=44) of cases and ineffective in 15%, the adenosine diphosphate test was effective in 22% (n=17) and ineffective in 58%. Dosage re-evaluations were proposed by the pharmacy when targets were not met. These results highlight the difficulty in obtaining and maintaining target rates. Our study did not establish a correlation between the duration under VAD and the number of accidents. By studying the 7 days before each accident, we found that even for patients previously anticoagulated and antiaggregated effectively, 71% of accidents are explained by a punctual but frank exit from the objective.","contentDiscussion":"","contentConclusion":"The number of accidents is not proportional to the frequency of tests, nor to the duration of implantation and it is essential to be constantly in the targets. A study described a decrease in accidents through the appointment of a referral physician to analyze the results on a daily basis and increased awareness of the care team. This allowed us to establish a sustainable strategy throughout the management of the patient, the pharmaceutical team already participates in and that could be improved.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"HANAFIA Omar"},{"id":99426,"num":"A34764OH","reference":"FC-092","title":"Levosimendan use in pediatric resuscitation: clinical impact and proper use of the medication.","formatedAuthors":"Omar HANAFIA (1), Bruno LESLUYES (1), Stéphane HONORE (1), Pierre BERTAULT-PERES (1), Fabrice MICHEL (1)
(1) Hopitaux Universitaires de Marseille, Marseille, FRANCE","contentIntroduction":"Levosimendan is used as a last resort in severe or decompensated chronic heart failure. For pharmacoeconomic reasons its delivery in our center is subject to a prior agreement, which is why the problem of positioning of this molecule in the therapeutic arsenal of our establishment arises. We carried out a study within the pediatric cardiac resuscitation unit, the objective of which was to analyse the habits of the department and the prescription conditions as well as the profile and become patients who received a levosimendan cure.","contentPatientsMethods":"This is a retrospective, monocentric study from January 2017 to June 2019. Whe analysed the service’s paper prescriptions. Thanks to the prescriptions and the computerized patient record, we recorded the cures, the prescription modalities, the length of hospitalization. We also sought to determine the clinical impact of the first cure via the serum level of nt-proBNP at D-1, D1 and D9 as well as the fate of patients at D30 and D60.","contentResultats":"18 patients were included, the average age was 12.8 months, and the H/F ratio was 0.63. On the first cure : only 6 cures respected the good practices, 7 patients had dobutamine prescribed before the first cure. 11 patients received several cures (2.9 total cures on average). The average length of hospitalization was 72 days. The rate of nt-proBNP decreased by an average of 49% between D-1 and D1 in 10 patients, and increased by 203% in the remaining 8 patients. Between D1 and D9, this rate decreased by an average of 52% in 8 patients and increased by 178% in the remaining 9 patients. At D30 of the first treatment, 1 patient had returned home, 10 were hospitalized, 3 were hospitalized under circulatory assistance and 4 had died. At D60 of the first treatment, 4 patients were at home, 6 were hospitalized, 3 were hospitalized under circulatory assistance, 5 died. The efficacy of levosimendan is evaluated by the improvement of the ventricular ejection fraction, unfortunately this ultrasound parameter does not appear in the PDI for each patient and therefore could not be analyzed in our study.","contentDiscussion":"","contentConclusion":"Levosimendan brings a proven benefit in certain physio-pathological terrains thanks to its singular mechanism of action. However, according to the literature, it is no more effective than dobutamine. Given its cost, it would be fair to continue this multidisciplinary work to redefine the place of this treatment in the therapeutic arsenal of our institution.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"HANAFIA Omar"},{"id":99427,"num":"A34473jR","reference":"FC-093","title":"Risk factors associated with prolonged ECMO in children : a referral center cohorte study","formatedAuthors":"Léa BERGEZ (1), Yael LEVY (1), Pierre Louis LEGER (1), Jerome RAMBAUD (1)
(1) Armand-Trousseau, Paris, FRANCE","contentIntroduction":"This study aimed to investigate the characteristics and clinical outcomes of children supported with prolonged ECMO (≥28 days) for severe acute respiratory failure or cardiac failure.","contentPatientsMethods":"We conducted a retrospective study in our referral center for ECMO between 2009 and 2020. All pediatric patients age from 28 days to 18 years-old supported with ECMO for ≥28 days were included. All neonatal indications for ECMO were excluded. We looked for pre-ECMO treatment such as mechanical ventilation settings, the use of prone positioning, nitric oxide, exogenous surfactant, neuromuscular blockers. We also gathered the ventilation settings at day 1, 3, 7, 14 and 21, outcome criteria as the median duration of ECMO, the length of invasive mechanical ventilation, the length of intensive care stays and the survival rate following intensive care discharge and 6 months after ICU discharge.","contentResultats":"On the 223 patients treated by ECMO during the study period, 14 (7%) patients underwent an ECMO run longer than 28 days. Median ECMO run duration was 44 days (28 – 122). Patients requiring a long ECMO run were younger (574 vs 1079 days), had a significantly lower PaO2/FiO2 ratio (51 vs 62, p < 0.001) and higher mean airways pressure (22 vs 18, p: 0.03). A lower tidal volume at day 7 of ECMO was significantly associated with long run (2.3 vs 4.6, p: 0.02). Higher FiO2 requirement on oxygenator and mechanical ventilator were significantly associated with long-run ECMO at day 7 and 14. Patients having a long run were suffering from more bleeding and infectious complications. Half of the deaths for long run patients were related to palliative care. Survival rate was lower for patients having a long run.","contentDiscussion":"","contentConclusion":"Long run ECMO represent a minority of all case of ECMO. Ventilator parameters at day 7 of ECMO may help to identified theses runs. Early identification of early patients at risk of a long run could be useful to prevent bleeding complication and to prepare potential bridge to transplantation.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"RAMBAUD Jerome"},{"id":99428,"num":"A34706ND","reference":"FC-094","title":"Cefepime Population Pharmacokinetics and Dosing Regimens Optimization in Pediatric Intensive Care Unit","formatedAuthors":"Noémie DE CACQUERAY (1), Deborah HIRT (2), Yi ZHENG (2), Emmanuelle BILLE (1), Pierre Louis LEGER (3), Jerome RAMBAUD (3), Julie TOUBIANA (1), Anais CHOSIDOW (3), Sophie VIMONT (3), Laurent CHOUCHANA (1), Agathe BÉRANGER (1), Jean-Marc TRELUYER (1,2), Sihem BENABOUD (2), Mehdi OUALHA (1)
(1) Necker, Paris, FRANCE ; (2) Cochin, Paris, FRANCE ; (3) Trousseau, Paris, FRANCE","contentIntroduction":"Cefepime is commonly used in pediatric intensive care units (PICU) while patients are subject to unpredictable variability in pharmacokinetic (PK) parameters leading to drug concentrations modification. This study aimed to build a population PK model for cefepime in critically ill children, to optimize and individualize initial dosing regimens.","contentPatientsMethods":"Children (age > 1 month and < 18 years, weight > 3 kg) receiving cefepime were included. Cefepime total plasma concentrations were measured using high performance liquid chromatography. Data were modelled using Monolix software and Monte Carlo simulations were performed using a PK target of 100% fT > MIC.","contentResultats":"Fifty-nine patients with median (range) age of 13.5 months (1.1 month-17.6 years) and 129 cefepime concentrations were included in the analysis. Cefepime data were best fitted by a one-compartment model and the selected covariates were body weight (BW) through allometric scaling and estimated glomerular filtration rate (eGFR) on clearance (CL). Mean population values for CL and volume (V) were 1.2 L.h-1 and 5.01 L, respectively. According to the simulations, 150 mg.kg-1.day-1 q6h over 3h or in continuous infusions better achieved the PK target in case of normal or augmented renal clearance.","contentDiscussion":"","contentConclusion":"Extended and more frequent or continuous cefepime infusions are needed in critically ill children with normal or augmented renal clearance. Cefepime displays narrow therapeutic index and require therapeutic drug monitoring.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"DE CACQUERAY Noémie"},{"id":99429,"num":"A34430MT","reference":"FC-095","title":"Meropenem and piperacillin population pharmacokinetics and dosing regimen optimization in critically ill children receiving continuous renal replacement therapy","formatedAuthors":"Michael THY (1,3), Saik URIEN (3,4), Frantz FOISSAC (3,4), Naim BOUAZZA (3,4), Emmanuelle BILLE (5), Agathe BÉRANGER (2,3), Mélanie RAPP (2,3), Gabrielle LUI (3,6), Fabrice LESAGE (2), Sylvain RENOLLEAU (2), Jean-Marc TRÉLUYER (3,4,6), Mehdi OUALHA (2,3)
(1) Assistance Publique-Hôpitaux de Paris, Infectious and tropical diseases department, Bichat University Hospital, Université de Paris, Paris, France, Paris, FRANCE ; (2) Assistance Publique-Hôpitaux de Paris, Paediatric Intensive Care Unit, Necker-Enfants Malades University Hospital, Université de Paris, Paris, France, Paris, FRANCE ; (3) EA 7323 - Pharmacology and Therapeutic Evaluation in Children and Pregnant Women, Université de Paris, France, Paris, FRANCE ; (4) Unité de recherche Clinique-Centre d’Investigation Clinique, Hôpital Cochin-Necker, Université Paris Descartes, Sorbonne-Paris Cité, 149 rue de Sèvres, 75015 Paris, France, Paris, FRANCE ; (5) Laboratoire de microbiologie, Hôpital Necker Enfants- Malades, Université Paris Descartes, Sorbonne-Paris Cité, 149 rue de Sèvres, 75015 Paris, France, Paris, FRANCE ; (6) Service de pharmacologie clinique, Hôpital Cochin, Université Paris Descartes, Sorbonne-Paris Cité, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France, Paris, FRANCE","contentIntroduction":"High variability in critically ill children receiving Continuous Renal Replacement Therapy (CRRT) increases the risk of inadequate concentrations. We aimed to develop a meropenem (MRP) and piperacillin (PIP) population pharmacokinetic (PK) model in this population and simulate dosing regimens to optimize patient exposure.","contentPatientsMethods":"MRP and PIP plasma concentration was quantified by high-performance liquid chromatography. PK was investigated using a non-linear mixed-effect modeling approach. Monte Carlo simulations were performed to determine the most appropriate therapeutic dosing regimens.","contentResultats":"Respectively, for MRP and PIP, 27 patients with an age of 4 [0-11] years old, weight of 16 [7-35] and 32 children with a median (IQR) postnatal age of 2 years (0–11), body weight (BW) of 15 kg (6–38), receiving continuous replacement renal therapy (CRRT) were included.\n For both MRP and PIP, concentration-time courses were best described by one-compartment model with first-order elimination with body weight (BW) and CRRT flow (Qd) for MRP and residual diuresis (Qu) for PIP as covariates explaining the lower between-subject variabilities on volume of distribution (V) and clearance (CL). For a 70-kg subject patient i, the final equations were:\n -For MRP: CLi = (CLpop x (BWi/70)0.75) x (Qd/1200)0.4), where CLpop and Vpop are 6 L/h and 35 L respectively.\n -For PIP: Vi=Vpop x (BW/70)1 and clearance (CL) : CLi = (CLpop x (BWi/70)0.75) x (Qu/0.06)0.12), where CLpop and Vpop are 7 L/h and 53 L respectively.\n After Monte-Carlo simulations for MRP and PIP, we suggested dosing regimens for a target of 100% fT > 4xMIC in Fig. 1.","contentDiscussion":"","contentConclusion":"Optimal antibiotic exposure in critically ill children under CRRT needs an adaptation of the doses to CRRT flow rate for MRP and to residual diuresis for PIP.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"THY Michael"},{"id":99430,"num":"A34593sk","reference":"FC-096","title":"Septic shock in severe trauma patients in pediatric intensive care","formatedAuthors":"Samira KALOUCH (1), Kawtar FAKHR (1), Wissal AISSAOUI (1), Abdelaziz CHLILEK (1)
(1) chu ibn rochd, Casablanca, MAROC","contentIntroduction":"Sepsis is the result of complex interactions between infectious microorganisms and the host's immune, inflammatory, and coagulant responses. The signs of sepsis constitute a continuum of increasing severity, ranging from the trivial association of tachycardia, tachypnea and fever with hyper leukocytosis or leukopenia to the occurrence of circulatory abnormalities, then organ dysfunction, and finally a state of shock that responds more or less easily to vascular filling and vasopressors.","contentPatientsMethods":"This is a descriptive and analytical retrospective study spread over 5 years (January 1, 2015-December 31, 2020) in the pediatric intensive care unit including 47 cases.\n Statistical analysis is done using SPSS software.","contentResultats":"In this study, we report 47 cases of septic shock in severe trauma patients collected in the pediatric intensive care unit of the children's hospital of CHU Ibn Rochd in Casablanca during the years 2020-2015. The study was carried out according to an operating sheet including demographic, clinical, biological, radiological and therapeutic data, followed by statistical analysis using SPSS software20 The average age is 75 months with a male predominance.\n The sites of infection were, in descending order, respiratory infection, bacteremia, urinary tract and skin. The germs mainly isolated were Acinetobacter Baumanii, Pseudomonas Ae, Staphylococcus aureus and Klebsiella. The evolution is fatal in 59.5% of cases.\n The prognostic factors retained were the delay of transfer to the intensive care unit >4 hours (p=0.003), the presence of more than 2 failing organs (p=0.004), the need for filling > 60ml/kg (p=0.02), the use of more than one active substance (p=0.006), the use of adrenaline (p=0.01) and the delay of antibiotic therapy >1 hour (p=0.0006).","contentDiscussion":"","contentConclusion":"Identification of the deficiencies in the management of septic shock and the application of the recommendations of the survivor sepsis campaign would improve the prognosis.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"KALOUCH Samira"},{"id":99431,"num":"A33907VC","reference":"FC-097","title":"First nosocomial infections in children supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO)","formatedAuthors":"Vladimir COUSIN (1), Robert RODRIGUEZ-VIGOUROUS (1), Oliver KARAM (2), Peter RIMENSBERGER (1), Klara POSFAY-BARBE (1)
(1) Hôpitaux Universitaires de Genève, Genève, SUISSE ; (2) Children’s Hospital of Richmond at VCU, Richmond, Va, ETATS-UNIS","contentIntroduction":"Veno-arterial (VA) Extracorporeal Membrane Oxygenation (ECMO) is a standard rescue procedure for patient with refractory shock in Pediatric Intensive Care Unit (PICU). They are at high risk of nosocomial infection with potential severe consequences. Aim of study was to determine the frequency, timing and microbiological specificity of VA-ECMO-related infection.","contentPatientsMethods":"Study period spanned from 01/2008 to 12/2014 with a retrospective charts review; inclusion criteria was patients with a VA-ECMO support for >6 hours. It was approved by local Ethics Committee (CE 14-231), who waived the need for informed consent. We recorded the first PICU infection during VA-ECMO support. Infection was defined as a positive microbiological sample with clinical signs of infection or clinical signs of severe infection without positive sample. Time to infection, length of VA-ECMO support, PICU stay and risk factors for infection were evaluated.","contentResultats":"During study period 41 patients were included, with a mortality of 53%. Mean time with VA-ECMO was 5,6 d (SD 4,7), mean time in PICU was 17.3 d (SD 14,3) (figure 1, stratified by infection status). Overall, 34% patients developed an infection, with an incidence of 60/1000 VA-ECMO days. Mean time to first infection was 3.8 d (SD 1.7), with Pseudomonas spp. as the most commonly detected microorganism (42%). Infected sites were ventilator-associated pneumonia (9/14), sternotomy infection (2/14), bloodstream (2/14) and urinary tract infections (1/14). Only length of VA-ECMO support and length of PICU stay were associated with infection: longer VA-ECMO support (>5 d) (OR 5.9 (CI 95% 1.4-24.6; p = 0.01) or longer PICU stay (>14 d) (OR 12 (95% CI 2.2-65.5; p = 0.004).","contentDiscussion":"In this monocentric study, we described the outcome and infectious complications in 41 patients with pediatric VA.ECMO. Our results underline the high proportion of infections in this population, its occurence early during the VA-ECMO support period. We highlighted the association of the time with VA-ECMO support and PICU length of stay with the occurrence of infection. However, such findings may be surrogate markers for sicker patients, who are intrinsically more at risk for nosocomial infections rather than a direct impact of duration of VA-ECMO support.","contentConclusion":"Pediatric patient with refractory shock supported by VA_ECMO are at high risk of nosocomial infection. Strategies aimed at preventing these infections may improve the outcome of these critically ill children","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1201","session":"FLASH COM - Pédiatrie 2","theme":"Pédiatrie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Pédiatrie médecin","contentInfoSupp2":"","presentateur":"COUSIN Vladimir"},{"id":99432,"num":"A34357IY","reference":"FC-098","title":"Non-invasive evaluation of the response to vascular filling in the first three hours of sepsis and septic shock by comparison of two diagnostic strategies","formatedAuthors":"Ilia YALAOUI (1,2), Abdellatif BENMATI (1,2), Abdelhafid BOUHROUM (1), Jean Louis TEBOUL (3)
(1) University 3 of Constantine, Faculty of Medicine, Constantine, ALGERIE ; (2) Preventive Medicine of Chronic Diseases Laboratory (Med Prev AC), Constantine, ALGERIE ; (3) The Kremlin-Bicêtre, Paris XI University, France, Paris, FRANCE","contentIntroduction":"Evaluating preload to predict response to vascular filling (RVF) prompts the clinician to have criteria that predict the effectiveness of vascular filling (VF). Changes in the time velocity integral (TVI) of aortic or subaortic blood flow and cardiac output (CO) measured by echocardiography, as well as the passive leg raise (PLR) test, are excellent methods for predicting preload reserve. The objective of this work is to decrease hospital mortality (HM) and to improve survival, quality of RVF prediction and occurrence of incidents related to VF in patients with sepsis or septic shock and in spontaneous ventilation.","contentPatientsMethods":"Through a prospective randomized prognostic trial, comparing two methods of evaluating the prediction of RVF, clinical and echocardiographic, of two groups of adult patients with sepsis or septic shock, in spontaneous ventilation and not previously infused. The clinical hemodynamic measurements collected before and after a 30 ml/kg of crystalloid filling test are : mean arterial pressure (MAP) and urine output (UO) in the control group (CG), as well as the TVI of the flow subaortic (TVIsa) and CO in the preload dependency group (PDG). In the PDG, TVIsa and CO measurements are also taken before and after PLR and VF.","contentResultats":"HM in responder patients is zero in sepsis and higher in septic shock and CG more than PDG (83,3% vs 72,7%). Survival is better in patients with PDG, in sepsis and in septic shock. RVF is significantly elevated in PDG compared to CG (92% vs 61,5%), and better in septic shock (77,3%) compared to sepsis (71,4%). There are more incidents in the GC compared to the GPD (19,2% vs 8%). The incidents are absent in sepsis and weak in septic shock (23,8% GC versus 8,7% GPD).","contentDiscussion":"Our study provided evidence in the acute phase of sepsis and septic shock in spontaneously ventilated patients, in predicting RVF and managing VF non-invasively and effectively by echocardiography, as well as in improving HM in septic shock, survival and the occurrence of VF-induced incidents.","contentConclusion":"The non-invasive prediction of RVF, by TVIsa measured by echocardiography, makes it possible to identify responders and non-responders in VF in real time, to test the hemodynamic efficiency of VF, to limit incidents related to overload during VF, to decrease mortality and to improve survival.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Rhodes A, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. 2017; 43(3) :304-77.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Jozwiak M, Monnet X, Teboul JL. Implementing sepsis bundles. Ann Transl Med. 2016; 4(17):332.40.","presentateur":"YALAOUI Ilia"},{"id":99433,"num":"A34526SD","reference":"FC-099","title":"ULTRASOUND-GUIDED SUBCLAVIAN VEIN CATHETERIZATION: INFRACLAVICULAR VERSUS SUPRACLAVICULAR APPROACH","formatedAuthors":"Saoussen DAFFEF (1), Becem TRABELSI (1), Ibtissem BEN TALEB (1), Hiba KTATA (1), Mechaal BEN ALI (1)
(1) Mohamed Taher Maamouri Teaching Hospital, Anesthesiology and intensive care unit, Nabeul, TUNISIE","contentIntroduction":"The subclavian vein (SCV) is the preferred site for central venous catheterization (CVC) in intensive care unit due to its ability to stay patent in hypovolemic situations and lower risk of infections. Difficulty in its ultrasonic visualisation with the infraclavicular (IC) approach is the reason why this approach has fallen out of favour. The ultrasound (US) guided supraclavicular (SC) approach seems to be a good alternative.\n The aim of this study was to compare the IC and the SC approaches in US-guided SCV catheterization.","contentPatientsMethods":"This was a prospective randomized study (NCT04637347). We included adult patients requiring a CVC in the superior vena cava area. Patients with infection at puncture site, coagulopathy, contralateral pneumothorax, trauma of clavicle and distorted anatomy of the neck were excluded from the study.\n Patients were randomly divided into two groups: US-guided SCV catheterization using either SC approach (SCGr) or IC approach (ICGr). We used long-axis scanning in combination with in-plane technique for all catheterizations. The primary outcome was the first attempt success rate. Overall success rate, venous scanning time, number of punctures, number of redirections, puncture time, guidewire insertion time, overall catheterization time, incidence of difficulties in catheterization and mechanical complications were secondary outcomes.","contentResultats":"We included 110 patients in this study: 55 in the SCGr and 55 in the ICGr. First attempt success rate was significantly higher in SCGr compared to ICGr (81.8% versus 63.6%; p<10-3). The overall success rate was significantly higher in SCGr compared to ICGr (96.4% versus 85.5%; p<10-3).Venous scanning time was significantly longer in the ICGr compared to the SCGr (21.7±15.6s versus 15.35±8.9s; p<10-3). The number of punctures was significantly lesser in the SCGr compared to the ICGr (1.2±0.5 versus 46±0.7; p<10-3). Regarding the number of redirections, the puncture time and the guidewire insertion time, no significant difference was observed between the two groups. The overall catheterization time was significantly shorter in SCGr compared to ICGr (63.13±31.7s versus 76.34±33.6s; p<10-3). The rate of mechanical complications were higher in the ICGr without significant difference (14% versus 5%; p=0.065). No cases of pneumothorax or malposition were observed in the SCGr however we obseved three cases of pneumothorax and two cases of malposition in the ICGr. The incidence of arterial punctures and hematoma formation were comparable between the two groups.","contentDiscussion":"","contentConclusion":"US-guided in-plane catheterization of SCV using SC approach is safe and seems to be a good alternative to the classic IC approach.","published_at":"2022-06-16T16:01:23.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:23.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DAFFEF Saoussen"},{"id":99434,"num":"A34560SS","reference":"FC-100","title":"TRANSCRANIAL DOPPLER: EASY OR DIFFICULT TECHNIQUE?","formatedAuthors":"Souhila SADAT (1), Dalila ZEGHDOUD (1), Dalila BOUGDAL (1)
(1) EHS salim zemirli , Alger, ALGERIE","contentIntroduction":"Transcranial Doppler is a specific monitoring of cerebral hemodynamics in the brain-damaged, allowing the evaluation of cerebral blood flow. Purpose of the study:Evaluate the DTC learning curve, because the acquisition of a medical technical gesture is part of a quality approach in the training of junior doctors.","contentPatientsMethods":"The study included ten residents, it took place in three phases,\n -The first phase: The participating doctors benefited from a theoretical presentation on DTP followed by a practical demonstration lasting three hours.\n -A second phase: Over a period of three weeks consisted for the junior doctors, a phase in which between 25 to 35 DTCs were carried out. The evaluation by the referent was carried out at each DTC in order to detect any anomalies.\n -The third phase: Follows the previous phase, it consists of performing ten DTCs by each candidate in order to complete their learning curve.\n The data for each exam was collected by the candidate. The candidate also provides the results of his DTC as well as that carried out by the referent. This examination concerns the search for the right and left middle cerebral artery with the values ??of the systolic, average and diastolic velocities, the value of the pulsatility index and the duration of each examination.","contentResultats":"The failure rate of completing the DTC was higher in the first and second attempts by our ten learners, which ranged from 60% to 80%, the success and failure rates were similar in the third and fourth trials. From the fifth attempts the success rates are higher than those of failures which vary from 20% to 30%.\n The comparison of the mean values ??of Vs, Vm, Vd and IP of the candidates compared to those of the referent made it possible to conclude that there is no significant difference between the results obtained.\n The comparison of the time taken to perform the DTC by the candidates compared to the referring doctor revealed the presence of a significant difference in the results obtained (P<0.001).","contentDiscussion":"","contentConclusion":"The DTC is an easy technique, quick to learn, but an evaluation of the sustainability of the acquisition of this technique by the learners is essential.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SADAT Souhila"},{"id":99435,"num":"A34581TK","reference":"FC-101","title":"Teaching intensive care nurses to recognize the misplacement of endotracheal and nasogastric tubes on chest radiographs","formatedAuthors":"Toufik KAMEL (1), Brice SAUVAGE (1), Karim LAKHAL (2), Gregoire OTTAVY (3), Ralf JANSSEN-LANGENSTEIN (4), Marine JACQUIER (5), Charlotte LARRAT (6), Gwenaëlle JACQ (7), Jérôme E. DAUVERGNE (2), Diane MAUGARS (3), Marie LABRUYERE (5), Véronique SIMEON (6), Cécile CUGNART (8), Christophe CHRISTOPHE GIRAULT (9), Thierry BOULAIN (1)
(1) Service de Médecine Intensive Réanimation, Centre hospitalier régional d'Orléans,, Orleans, FRANCE ; (2) Service d'Anesthésie-Réanimation, hôpital Laënnec, Centre Hospitalier Universitaire,, Nantes , FRANCE ; (3) Service de médicine intensive-réanimation, CHU de Nantes, France , Nantes, FRANCE ; (4) Service de Médecine Intensive et Réanimation – Hautepierre, CHU de Strasbourg, , Strasbourg, FRANCE ; (5) Service de Médecine Intensive et Réanimation, CHU de Dijon, , Dijon, FRANCE ; (6) Service de Médecine Intensive et Réanimation CHRU de Tours, , Tours, FRANCE ; (7) Service de Réanimation médico-chirurgicale, centre hospitalier de Versailles , Versailles, FRANCE ; (8) Rouen University Hospital, Medical Intensive Care Unit, , Rouen, FRANCE ; (9) Normandie Univ, UNIROUEN, EA 3830, Rouen University Hospital, Medical Intensive Care Unit, Rouen, FRANCE","contentIntroduction":"To assess the effectiveness of a single standardized training on the ability of intensive care registered nurses (RN) to recognize the misplacement of endotracheal and nasogastric tubes on bedside chest radiographs of intensive care unit (ICU) patients.","contentPatientsMethods":"In 8 French ICUs, RNs received a 110-min standardized teaching on the position of endotracheal and nasogastric tubes on chest radiographs. Their knowledge was evaluated within the subsequent weeks. On 20 chest radiographs, each with an endotracheal and a nasogastric tube, they had to indicate whether each tube was in proper or incorrect position. A lower bound of the 95% confidence interval (95%CI) of the mean correct response rate (CRR) was chosen to indicate the training success when > 90%. Residents of the participating ICUs were subjected to the same evaluation (without prior specific training).","contentResultats":"One hundred eighty-one RNs were trained and evaluated, and 110 residents evaluated. The mean CRR in RNs was 84.6% (95%CI: 83.3-85.9), significantly higher than in residents (81.4% [95%CI:79.7-83.2]) (P=0.003 by t test). Linear mixed modelling handling the centers as random effect variable confirmed the significant difference (P<0.0001) in CRR between RNs and residents as shown in Figure 1. For misplaced nasogastric tubes, the mean CCR in RNs was 95.9% (95%CI: 93.9-98.0).\n Age, sex, seniority, delay between training and evaluation (for RNs) and period of evaluation within the semester of internship (for residents) did not significantly impact (all P>0.05) on the mean CRR, either in the whole set of participants or in RNs and residents taken separately.","contentDiscussion":"","contentConclusion":"The ability of trained RNs to detect tube misplacement was higher than that observed among residents and was considered satisfactory for detecting misplaced nasogastric tubes. This is encouraging but insufficient to ensure patients safety. Transferring responsibility for reading radiographs to detect the misplacement of endotracheal tubes to intensive care RNs will need a more advanced or more in-depth teaching method than that used in this study.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"KAMEL Toufik"},{"id":99436,"num":"A34344Db","reference":"FC-102","title":"Involvement of healthcare teams in the evaluation and selection of smart-pumps in intensive care.","formatedAuthors":"Léo-Paul BRUAIRE (1), Nathalie BECK (1), Jean-Charles PIERRE DE LA BRIÈRE (1), Guillaume LEVEAUFRE (1), Damien ROUSSEL (1), François LECOUTOUR (1), Aurélie JORET (1), Isabelle GOYER (1), David BROSSIER (1)
(1) CHU de Caen, Caen, FRANCE","contentIntroduction":"Medication errors are a major public health issue. As part of the project of dematerialization of the patient record in our intensive care units, the computerization of the medical prescription and the securing of the administration of the drug were among our objectives. In order to secure the drug circuit and reduce the drug errors, many scientific societies recommend the use of injectable drug delivery devices connected to the computerized medical record, called “smart-pumps”. The main objective of the study was to compare 2 ranges of smart-pumps available in France. The secondary objective was the involvement of the paramedical teams in the choice of their future work tools.","contentPatientsMethods":"We carried out a prospective monocentric, comparative, interventional study, without human involvement of the ranges proposed by B.Braun and a second company between September the 23rd and October, the 15th of 2019, in adult, pediatric and neonatal intensive care units of the Caen UH. This assessment was coupled with a satisfaction survey. All staff nurses received a training in the use of the equipment. Subsequently, the nurses trained on the 2 ranges proceeded to the successive evaluation of these throughout two scenarios of application of medical prescriptions. The order in which each nurse evaluated the 2 ranges was randomized. The main criterion of judgement was the overall satisfaction of nursing staff with the use of the devices. The secondary criteria concerned the handling of materials and consumables as well as navigation in drug libraries and the duration of each scenario, timed by a project member.","contentResultats":"77 agents (25% of the nurses concerned) were trained, 54 of whom evaluated the two ranges. The fulfilment of the medical prescription and the installation of the tubing in the pump was considered longer with the range proposed by B.Braun. No other significant difference was observed. However, 56% of nurses advised the range proposed by B.Braun which appeared safer, more ergonomic and less bulky.","contentDiscussion":"","contentConclusion":"To our knowledge, no such study has ever been published. Without observing major differences in use between the two companies, this comparison process allowed us to determine the equipment that seemed to best meet the expectations of the paramedical teams. Moreover, by involving and following the teams in the choice of their work equipment we hope to have strengthened the adherence of the teams to the change of practice induced by the use of smart pumps.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BROSSIER David"},{"id":99437,"num":"A34762OH","reference":"FC-103","title":"Influence of clinical pharmacist presence on acceptance and delivery of pharmaceutical interventions in a pediatric resuscitation unit","formatedAuthors":"Omar HANAFIA (1), Guillaume HACHE (1), Pierre BERTAULT-PERES (1), Stéphane HONORE (1), Fabrice MICHEL (1)
(1) Hopitaux Universitaires de Marseille, Marseille, FRANCE","contentIntroduction":"Studies have shown that medication errors are common in intensive care units. The drug management of pediatric and neonatal populations is particularly at risk of iatrogenia due to the pathophysiological characteristics of these populations, the lack of suitable pharmaceutical forms and based on weak agreements. In addition, the clinical situations of these patients are serious and often require complex therapeutic strategies. Securing drug prescriptions is critical in these situations.The objective of this study was to measure the influence of the presence of the clinical pharmacist in the clinical department on the safety of drug prescriptions.","contentPatientsMethods":"We conducted an observational study, before/after a pharmacist was involved in a 30-bed critical care unit. The analysis and daily pharmaceutical validation of prescriptions were performed from the pharmacy on the first part of the study (before). The issuance of Pharmaceutical Interventions (PI) was conducted by telephone and plotted on the printed prescription. For the second part (after), the pharmaceutical validation of the prescriptions was carried out in the service and the PI transmitted orally to the prescribers in person and plotted in the same way. The main criterion for evaluating the securing of prescriptions was the number of PI issued. We also characterized the nature of the PI, the consensus achieved orally, and the achievement of the prescription change suggested by the PI.","contentResultats":"We have 351 PI out of 126 days before, these PI mainly concerned overdoses (52%), route and/or inappropriate administration (17%) and non-conformities to the repository (10.8%). 179 children were affected by these IP.\n We found 1120 IP over 287 days, these IP mainly concerned monitoring (27.8%), overdoses (21.8%) and under dosing (10.1%). 300 children were affected by these IP.\n \n We observed an increase in the number of IP performed per day (2.8 vs 3.9), the average number of IP per patient (2 vs 3.7). An increase in the number of IP accepted (267 vs 756; p=0.036) and the number of implementations (183 vs 629; p<0.001) was highlighted","contentDiscussion":"","contentConclusion":"The presence of the pharmacist in the clinical department increased the number and relevance of PI performed. The nature of PI has evolved with a more patient-centred orientation. Acceptance and achievement rates are better, the percentage of PI achieved is higher, and these results show that PI are both better monitored and better monitored. Risk reduction is best with pharmaceutical expertise through the presence of a clinical pharmacist in the care unit","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HANAFIA Omar"},{"id":99438,"num":"A34393SA","reference":"FC-104","title":"A prospective pharmacist review of drug-related problems after ICU discharge: preliminary data.","formatedAuthors":"Sébastien ANDRÉ (1), Anne-Françoise ROUSSEAU (2,3), Camille COLSON (2,3), Benoît MISSET (2,3), Manon GILLET (1)
(1) Hospital Pharmacy Department, University Hospital of Liège, Liège, BELGIQUE ; (2) Intensive Care Department, University Hospital of Liège, Liège, BELGIQUE ; (3) University of Liège, Liège, BELGIQUE","contentIntroduction":"A stay in an intensive care unit (ICU) and the transitions of care are known to be at risk of drug-related problems (DRPs). These problems may contribute to readmissions and development of post-intensive care syndrome. The objective of this monocenter prospective study was to describe the prevalence of specific DRPs in patient’s post-ICU drug treatments.","contentPatientsMethods":"Adults with an ICU stay ≥7days between 16th November 2021 and 25th January 2022 were included if they were enrolled in our post-ICU follow-up program. A pharmacist conducted a full medication review including medication reconciliation. This review was planned in general ward, during the week following ICU discharge. The pharmacist identified potential DRPs that were classified using the Pharmaceutical Care Network Europe Classification for Drug-Related Problems. Tailored interventions were also delivered to general wards clinicians based on identified DRPs.","contentResultats":"We included 29 patients (72.4% men, age 59 [33-76] years, ICU stay 19 [7-95] days). Drug treatments were reviewed 5 [2-9] days after ICU discharge. A total of 148 DRPs were identified: 27/29 patients (93.1%) experienced at least 1 DRP and a median of 5 [0-12] DRPs were observed per patient. Most DRPs referred to (potential) adverse drug events (86/148, 58.1%), (potential) non-optimal effect of drug treatment (26/148, 17.6%) and unnecessary drug-treatment (26/148, 17.6%). The main cause of DRPs was related to drug selection (80/160, 50.0%) comprising absence of indication, inappropriate drug according to guidelines and inappropriate combination of drugs. Other causes of DRPs included prolonged duration of treatment (36/160, 22.5%), inappropriate dose or dosage regimen (23/160, 14.4%) and medication reconciliation problem (7/160, 4.4%). Drugs involved in DRPs belonged mainly to the nervous system group, the alimentary tract and metabolism group, and the cardiovascular system group. The most common drugs implied were tramadol and pantoprazole. Based on identified DRPs, 147 pharmacist interventions were discussed with the clinicians. Withdrawal of a drug was the predominant intervention (75/147, 51.0%) followed by provision of information about the DRP, dosage regimen modification, dose change, initiation or resumption of a drug and drug switch. 74.2% of all interventions were accepted by the clinicians.","contentDiscussion":"","contentConclusion":"DRPs were common after ICU discharge. Drugs of the nervous system group and proton pump inhibitors probably require sustained attention. Future research should evaluate the impact of pharmaceutical interventions on mid-term outcomes of ICU survivors.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1202","session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ANDRÉ Sébastien"},{"id":99439,"num":"A34381RC","reference":"FC-105","title":"Evaluation of a negative pressure aerosol protection box to prevent airborne transmission of SARS-COV-2 to healthcare providers in pediatric intensive care","formatedAuthors":"Rotava Buratti CECÍLIA (1,2), Philippe JOUVET (1), Armelle BRIDIER (1), Marc VEILLETTE (3), Caroline DUCHAINE (3)
(1) Sainte Justine Research Center, University of Montreal, Montreal, CANADA ; (2) Postgraduate program in child and adolescent health, Universidade Federal do Rio Grande do Sul, Porto Alegre, BRESIL ; (3) Research Center of the institut universitaire de cardiologie et de pneumologie de Québec, Quebec City, CANADA","contentIntroduction":"High contagiousness of SARS-COV-2 is caused by bioaerosols’ emission1. The risk of healthcare providers (HCPs) developing infectious diseases through contact with patients is well recognized, and clinical situations involving tissue manipulation with high viral load called \"aerosol-generating procedures\" (AGP) may increase this risk2. The aim of this study was to investigate the impact of the aerosol protection box, the Splash-Guard Caregivers (SGGC), on the presence of viral particles after an AGP.","contentPatientsMethods":"Prospective observational study conducted between April and June 2020, including the HCPs in charge of children admitted to a Pediatric Intensive Care Unit who tested positive for COVID-19. SGCG (https://rsr-qc.ca/Splashguard-cg/) was not used systematically and room patients analyzed were divided in: SGCG+ and SGCP-. Virus detection was performed in the single room patient's environment using two methods (air pumps and swabs) on several sites: 1) on the air one meter from the patient’s head (wearable pumps), 2) inside the SGGC from the patient’s air (if used), also 3) on the air near each HCPs (wearable pumps), and 4) at each HCPs forehead (swab) after an AGP. Samples were analyzed for SARS-COV-2 RNA by qPCR.","contentResultats":"Eight batches of samples were performed in the single room of SARS-COV-2+ child (SGCG+ n=3 and SGCG- n=5). Five samples (11.4%) were qPCR positive for SARS-COV-2 among the 44 analyses. Three of these (14.3%) among the 21 analyses from the group SGCG-: in the air before the AGP (n=1), in the air near HCP’s head after the AGP (n=1), and in the HCP forehead swab after the AGP (n=1). In the group SGCG+, 2 positive samples (8.7%) were observed among the 23 analyses in the HCP forehead swab (n=1) and in the air near HCP’s head (n=1), both after an AGP (see Supplementary Table). None of the HCPs studied were infected by SARS-COV2.","contentDiscussion":"","contentConclusion":"Our results document the presence of SARS-COV2 in infected children environment. The protection effect of SGCG needs additional research.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":null,"session":"FLASH COM - Evaluations des pratiques","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"van Doremalen N et al: Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med 2020","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Nguyen LH et al : Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study. Lancet Public Heal 2020","presentateur":"JOUVET Philippe"},{"id":99440,"num":"A34703RA","reference":"FC-106","title":"Acute kidney injury in patients with necrotizing soft tissue infection in intensive care unit: a comparative retrospective study","formatedAuthors":"David ROZENBLAT (1), Tomas URBINA (4), Camille HUA (5), Keyvan RAZAZI (1,2,3), Armand MEKONTSO-DESSAP (1,2,3), Nicolas DE PROST (1,2,3), Romain ARRESTIER (1,2,3)
(1) Service de Médecine Intensive Réanimation, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, CEDEX, Créteil, 94010 Paris, France, Créteil, FRANCE ; (2) Groupe de Recherche Clinique CARMAS, Faculté de Santé de Créteil, Université Paris Est Créteil, CEDEX, Créteil, 94010 Paris, France, Créteil, FRANCE ; (3) INSERM, IMRB, Université Paris Est Créteil, CEDEX, Créteil, 94010 Paris, France, Créteil, FRANCE ; (4) Service de Médecine Intensive-Réanimation, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, France, Paris, FRANCE ; (5) Service de Dermatologie, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, CEDEX, Créteil, 94010 Paris, France, Créteil, FRANCE","contentIntroduction":"Necrotizing soft tissue infections (NSTI) are life-threatening bacterial infections and often requires admission to intensive care unit (ICU). Severity and specificities of this pathology, such as micro-organisms involved, rhabdomyolysis and nephrotoxic drugs used, could lead to a higher incidence of acute kidney injury (AKI) than in other sepsis conditions. Our objectives were to describe the clinical and biological characteristics of NSTI related AKI and to compare its frequency to a cohort of non-NSTI septic shock.","contentPatientsMethods":"We conducted a single-center retrospective comparative study of patients with NSTI admitted in ICU between 2006 and 2021. Patients < 18 years old, patients with end-stage renal disease requiring dialysis and patients with nosocomial NSTI acquired after 7 days of hospitalization were excluded. Clinical, biological characteristics and outcomes of NSTI patients with AKI were compared to NSTI patients without AKI. A matching analysis of NSTI patients to a historical cohort of patients with septic shock non related to NSTI and admitted in ICU between 2010 and 2013 was performed.","contentResultats":"Overall, 77 patients with NSTI were included. Clinical and biological characteristics are described in table 1. 65 patients (84,4%) developed AKI and 29 (44,6%) displayed stage 3 KDIGO with fourteen patients (21,5%) needed renal replacement therapy (RRT). Time from ICU admission to AKI onset was 1 (0-2) days. Shock at ICU admission was independently associated with AKI (OR=6.2 [1.3-44.0], p=0.045). Initiation of antibiotic therapy before ICU admission (OR=0.05 [0.0-0.6], p=0.045) and Enterobacteriaceae infections (OR=0.17 [0.0-0.7], p=0.02) were associated with a lower risk of AKI. Rhabdomyolysis was not associated with AKI. Total ICU length of stay and mortality were slightly higher for patient with AKI but not statistically different. 45 patients with septic shock non related to NSTI were matched to 45 NSTI patients. The rate of AKI (95,6% vs 84,4%, p=0,16) and the need for RRT (31,1% vs 26,7%, p=0,64) were not statistically different between the two groups.","contentDiscussion":"","contentConclusion":"AKI is common in patients with NSTI but is not significantly associated with outcome. Risk factors for AKI in patients with NSTI are shock at ICU admission and late initiation of antibiotherapy, however NSTI is not a risk factor of AKI compared to other etiology of septic shock.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ROZENBLAT David"},{"id":99441,"num":"A34319AO","reference":"FC-107","title":"Cardiorenal syndrome in piglets: development and characterization of a preclinical model","formatedAuthors":"Arthur ORIEUX (1,2), Laurence PIERONI (2,4), Sarah DROUIN (2,4), Chloé SAMSON (2), Simon DANG VAN (3), Tiffany MIGEON (2), Juliette HADCHOUEL (2), Julien GUIHAIRE (3), Olaf MERCIER (3), Pierre GALICHON (2,4)
(1) Service de Médecine Intensive Réanimation - CHU de Bordeaux, Bordeaux, FRANCE ; (2) INSERM UMR_S1155, CoRaKiD - Sorbonne Université, Hôpital Tenon, Paris, FRANCE ; (3) INSERM UMR_S999, Hôpital Marie Lannelongue, GHPSJ, Université Paris Saclay, Le Plessis-Robinson, FRANCE ; (4) AP-HP, Paris, FRANCE","contentIntroduction":"Cardio-renal syndromes (CRS) type 1 and 2 are complex disorders in which cardiac dysfunction leads to kidney dysfunction. However, the mechanisms remain incompletely explained, in particular in right heart failure (RHF). Our objective was to develop an original preclinical model of CRS secondary to RHF associated with post embolic pulmonary hypertension (PH) in piglets.","contentPatientsMethods":"Twelve 2-month-old large white piglets were randomized: group with induction of PH by ligation of the left pulmonary artery followed by weekly iterative embolization (soft tissue adhesive) of the right lower pulmonary artery, or SHAM control group (sham interventions) (Figure 1). The sacrifice is made after 5 embolizations. We performed hemodynamic evaluation (right cardiac catheterization), echocardiography, laboratory blood, and urine tests. Histological evaluation and immunostaining of renal damage and repair were fulfilled. Measured glomerular filtration rate (GFR) procedures by injection of an exogenous tracer were repeated weekly.","contentResultats":"At sacrifice, mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR) and central venous pressure (CVP) were significantly higher in the PH group: 32 ± 10 vs 13 ± 2 mmHg (p=0.001); 9.3 ± 4.7 vs 2.5 ± 0.4 mmHg (p=0.004) and 10 ± 4 vs 6 ± 2 mmHg (p=0.04) while the cardiac index (CI) was not different. Piglets with PH had right ventricular dysfunction and higher troponin I (302 [53-3054] vs 33 [17-47] ng/mL; p=0.03). PH piglets showed increased histological marker of kidney injury (acute tubular necrosis -ATN-) and repair (proliferation assessed by Ki67). Albuminuria was increased (4.4 ± 0.6 vs. 2.9 ± 0.4 mg/L; p<0.001) while serum creatinine (SCr) and uremia were not significantly different between the two groups. Unlike the estimated GFR, the measured GFR decreases from the 3rd week of the protocol. We reported a correlation between PH parameters and kidney function: mPAP (R2=0.4, p=0.03), PVR (R2=0.50, p=0.01) and CVP (R2=0.37; p=0.04), but not with CI.","contentDiscussion":"","contentConclusion":"We reported the first porcine model of SCR on RHF secondary to PH. Renal dysfunction was characterized by ATN, increased albuminuria, and low measured GFR. The GFR estimated from SCr did not informed on renal dysfunction in these young piglets, unlike the measured GFR.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ORIEUX Arthur"},{"id":99442,"num":"A34605NB","reference":"FC-108","title":"Impact of positive fluid balance on outcomes in COVID-19 critically ill patients with ARDS","formatedAuthors":"Nabil BOUGUEZZI (1), Radhouane TOUMI (1,2), Iyed MAATOUK (1), Amir BEDHIAFI (1), Hajer ZOUARI (1), Khalil MAATOUK (1), Khaoula MEDDEB (1,2), Imene BEN SAIDA (1,2), Mohamed BOUSSARSAR (1,2)
(1) Medical Intensive Care Unit, Farhat Hached University Hospital, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, University of Sousse, Sousse, TUNISIE","contentIntroduction":"COVID-19 pandemic represents a major public concern worldwide. Acute respiratory distress syndrome (ARDS) and lung failure are the main lung diseases found in COVID-19 patients. In ARDS patients, positive fluid balance can be associated with prolonged mechanical ventilation, more intensive care unit (ICU) complications, and higher mortality. Objective: The aim of this study was to evaluate the effect of fluid balance on morbidity and mortality in COVID-19 patients admitted to the ICU.","contentPatientsMethods":"We conducted a retrospective observational study from March 2020 to October 2021 in a Medical ICU. Data concerning daily fluid balance, cumulative fluid balance at day 7, PaO2/FiO2 (P/F) ratio and outcomes of Critically Ill COVID-19 patients were obtained from medical records. The acute kidney injury (AKI) severity was classified according to the Kidney Disease Improving Global Outcomes guidelines. The study sample was divided into 2 groups according to fluid balance. Different outcomes (length of stay, invasive mechanical ventilation, acute kidney injury and death) were compared between the 2 groups.","contentResultats":"During the study period, 442 critically ill COVID-19 patients were admitted to our ICU. Positive fluid balance was found in 46% of patients (n=207), and negative fluid balance was found in 53% of cases (n=235), with a mean of 2271±2285ml and -2144±2369ml respectively. The mean cumulative fluid intake at day 7 was -76±3206 ml. Patients with positive fluid balance had a higher incidence of AKI (58.9%, n=122) versus (37%, n=87) (p<0.001), of capillary leak (39%, n=80) versus (27.8%, n=63) (p=0.013) and a higher mortality (54.4%, n=112) versus (43.8%, n=102) (p=0.027). Mean length of stay was the same for the 2 groups (10.16±6.15days versus 9.99±6.68days, p=0.79). The majority (50.6%, n=118) required invasive mechanical ventilation (p=0.11). P/F improved from 132±77 on day 1 to 197±90 on day 7 in negative fluid balance group (p<10-3). Mean P/F was stable from day 1 and day 7 in positive fluid balance group (123±55 and 129±51 respectively, p=0.36). Mean fluid balance at day 7 was significantly less for survivors than non survivors (-505±3364 ml and 413±2961 ml respectively, p=0.002).","contentDiscussion":"","contentConclusion":"Our study showed that patients with excessive fluid balance had more ICU complications and higher hospital mortality. Therefore, restrictive fluid strategies should be used to improve oxygenation and reduce mortality among COVID-19 patients.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUGUEZZI Nabil"},{"id":99443,"num":"A34633oM","reference":"FC-109","title":"Acute Kidney Injury (AKI) in the intensive care unit (About 151 cases)","formatedAuthors":"Khalid KHALEK (1), Malika OULAHIANE (1), Aziz BOUHOURI (1), Rachid AL HARRAR (1)
(1) Service de réanimation chirurgicale des urgences(P.33), CHU Ibn Rochd, Casablanca, Casablanca, MAROC","contentIntroduction":"Acute kidney injury (AKI) is a frequent complication in intensive care units (ICU). The mortality remains high due to the aging of the affected population, the multiplicity of causes generating it, the association with other visceral failures and the frequent evolution in a septic context. The aim of this study is to study the different epidemiological and therapeutic aspects of AKI and try to determine the predictive factors of mortality in our population","contentPatientsMethods":"a descriptive and analytical cross-sectional study, which focused on 151 records of patients admitted to the ICU, who presented an AKI on admission or developed it during hospitalization. This study is spread over a period of 24 months, from 01/2019 to 12/2020.","contentResultats":"The incidence of AKI in our series was 17.32%. The average age of the patients was 49 +/- 18 years with a male predominance (sex ratio M/F 2.14). The most common risk factors were: injection of contrast (77.9%), mechanical ventilation (67.8%), use of vasopressors (64.2%), nephrotoxic drugs (58%), diabetes (23.3%) and arterial hypertension (19.2%). The time of appearance of AKI was 2 +/- 3 days. KDIGO stage 3 was predominant in our patients with a percentage of 53.6% followed by stage 1 (23.8%), and lastly stage 2 with a percentage of 22.5%. Dialysis was used in 18% of the patients. The mortality rate in our series was 62.33% and the factors found to have a significant relationship with death were: age, mechanical ventilation, use of vasopressors, multivisceral failure and septic shock.","contentDiscussion":"","contentConclusion":"A better knowledge of the risk and prognostic factors of AKI could be a major asset for a more effective management","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"John R. Prowle, Christopher J. Kirwan and Rinaldo Bellomo. Fluid management for the prevention and attenuation of acute kidney injury. Nat. Rev. Nephrol. 10, 37–47 (2014):11. doi/10.1038/nrneph.2013.232","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Gaudry S, Ricard J-D, Leclaire C, Rafat C, Messika J, Bedet A, et al. Acute kidney injury in critical care: Experience of a conservative strategy. J Crit Care. déc 2014;29(6):1022?7.","presentateur":"KHALEK Khalid"},{"id":99444,"num":"A34661CD","reference":"FC-110","title":"Association of nitrogen balance trajectories with clinical outcomes in critical ill COVID-19 patients: a retrospective single center cohort study","formatedAuthors":"Claire DUPUIS (1), Alexandre BRET (1), Alexandra JANER (1), Olivia GUIDO (1), Radhia BOUZGARROU (1), Loïc DOPEUX (1), Gilles HERNANDEZ (1), Olivier MASCLE (1), Laure CALVET (1), François THOUY (1), Kévin GRAPIN (1), Mireille ADDA (1), Yves BOIRIE (1), Bertrand SOUWEINE (1)
(1) CHU Gabriel Montpied, CHU Clermont Ferrand, Clermont Ferrand, FRANCE","contentIntroduction":"The intensity and duration of the catabolic phase in COVID-19 patients might differ between survivors and no survivors. The purpose of the study was to assess the association between NBAL trajectories and outcome in critical ill COVID-19 patients.","contentPatientsMethods":"This retrospective study was conducted in intensive care at Clermont Ferrand University Hospital, France. From January 2020 to May 2021. The present study was approved by the Ethics Committee of Clermont Ferrand. Patients over 18 years old with a severe COVID-19 disease were eligible. Patients were excluded if they were referred from another ICU, if their ICU length of stay was < 72 hours, and if they were treated by renal replacement therapy during the first seven days after ICU admission.\n The primary objective was to compare the profile of NBAL during the first two weeks after ICU admission between the patients with ICU death and the other patients.\n All data were prospectively collected and comprised details on ICU admission and during ICU stay. Vital status was collected at day 60. NBAL was estimated as proposed by Dickerson et all (Ref 1).\n Statistical analysis\n Comparisons between the evolution of NBAL depending on outcome was achieved using 2 level ANOVA. At day 3, 5 and 7, to represent the relationship between NBAL and protein intake, linear and non nonlinear models were achieved and the protein intakes necessary to reach a zero NBAL were determined. Sub-group analyses were achieved according to BMI, age, gender.","contentResultats":"99 patients were included in the study. Their characteristics are reported in table 1.\n On day 3, a negative similar NBAL was observed in survivors and non survivors: -16.4 g/d[-26.5 ; -3.3] and -17.3 g/d[-22.2 ; -3.8](pval=0.54). Then, the trajectories of NBAL over time differ between survivors and non survivors(pval=0.01).\n In survivors, NBAL increased over time (Patients with a net protein catabolism: 73.9% at day 3 versus 45.5% at day 14) whereas in non survivors, NBAL decreased from day 2 to day 6, and thereafter increased slowly up to day 14 (Patients with a net protein catabolism: 73.3% at day 3 vs 78.9% at day 14).\n Administrating higher protein amounts were associated with higher NBALs.","contentDiscussion":"","contentConclusion":"We reported a prolonged catabolic state in COVID patients which seemed more pronounced in non survivors than in survivors. Our study underlined the need for monitoring urinary nitrogen excretion to guide protein intakes in COVID-19 patients.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Dickerson, Nutrition, 2005","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DUPUIS Claire"},{"id":99445,"num":"A34498JQ","reference":"FC-111","title":"Management of Renal Replacement Therapy in adults French Intensive Care Units: A survey practices at the bedside (READIAL)","formatedAuthors":"Florian JOLLY (1), Marine JACQUIER (1,5), Delphine PECQUEUR (2,3), Marie LABRUYÈRE (1,2), Christophe VINSONNEAU (4), Isabelle FOURNEL (2), Jean-Pierre QUENOT (1,2,5)
(1) CHU Dijon, Dijon, FRANCE ; (2) INSERM, CIC 1432, Module Epidémiologie Clinique, Dijon, FRANCE ; (3) CHU Dijon-Bourgogne, Centre d’Investigation Clinique, Module Epidémiologie Clinique/Essais Cliniques, Chu Dijon-Bourgogne, Centre D’Investigation Clinique, Module Epidémiologie Clinique/essais Cliniques, FRANCE ; (4) Centre Hospitalier de Bethune, Service de Médecine Intensive Réanimation-Unité de Sevrage Ventilatoire et Réhabilitation, Bethune, FRANCE ; (5) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, université de Bourgogne-Franche Comté, Dijon, FRANCE","contentIntroduction":"In France, recommendations for renal replacement therapy (RRT) in the intensive care unit (ICU) were published in 2015 and their uptake was recently assessed in a nationwide self-report online survey 1. We performed an evaluation of real-life practices in the field in terms of RRT in a representative sample of ICUs across France.","contentPatientsMethods":"The READIAL study was performed from 1 July to 5 October 2021. It was an evaluation of professional practices, and each centre was required to prospectively include 5 consecutive patients. Patients who required initiation of a first RRT using a hemodialysis catheter were eligible for inclusion. Patients with chronic renal failure requiring RRT through a tunnelled catheter or an arterio-venous fistula were excluded.","contentResultats":"A total of 67 centres (83% of those contacted) agreed to participate, and included a total of 295 analysable patients (8 patients were erroneously included and therefore excluded from analysis). We found divergences between previously declared practices1 and actual practice observed in this study. The main indications for initiation of RRT are detailed in Figure 1 (left panel), and the main sites of insertion of the first hemodialysis catheter are shown in Figure 1 (right panel). The vast majority of centres used citrate, unfractionated heparin or NaCl as a catheter lock solution (47%, 24% and 21% respectively).","contentDiscussion":"","contentConclusion":"In this evaluation of professional practices that collected data at the bedside, the modalities of initiation of RRT in the ICU in patients with acute kidney failure were found to be globally in line with guidelines and literature data. The results should be interpreted in light of the limitations inherent to this type of study.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Quenot JP, Amrouche I, Lefrant JY, et al. Blood Purification 2021;4:1-10","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"QUENOT Jean-Pierre"},{"id":99446,"num":"A34339CV","reference":"FC-112","title":"Scleroderma cardiac crisis: a-life-threatening but reversible complication of systemic sclerosis","formatedAuthors":"Clara VIGNERON (1), Frédéric PÈNE (1), Julien CHARPENTIER (1), Luc MOUTHON (1), Benjamin CHAIGNE (1)
(1) Hôpital Cochin, Paris, FRANCE","contentIntroduction":"Systemic sclerosis (SSc) heart involvement account for 30% of SSc patient’s deaths.","contentPatientsMethods":"We retrospectively studied patients with previous diagnosis of SSc admitted to the ICU for acute cardiac dysfunction between 2012 and mid-2021.","contentResultats":"Nine female patients were included, mainly with diffuse SSc (n=7, 78%). Six (67%) had digital ulcers. All but one patient complained about physical cardiac symptoms (n=8, 89%), 5 (56%) had electrocardiogram modifications. Biological exams revealed elevated troponin (705 µg/l [421-1582]) and Nt-pro-BNP (16062 ng/l [10419-40738]). Patients exhibited severe left ventricular ejection fraction (LVEF) impairment (20% [10-20] vs 58% [53-60] before ICU admission (p=0.0002)) requiring vasopressors and/or inotropes for 7 patients (78%) and mechanical ventilation or renal replacement therapy for 4 patients (44%). LVEF spontaneously improved during ICU stay (LVEF 40% [30-40] vs 20% [10-20], p=0.0007) and returned to baseline within 6 months following ICU discharge (LVEF 53% [40-63] vs 58% [53-60]) (Figure 1). Seven (78%) patients survived the ICU-stay and 4 (44%) were alive at 6 months.","contentDiscussion":"","contentConclusion":"We report an uncommon and specific severe acute life-threatening cardiac dysfunction in SSc patients, which can be reversible but remains associated with a poor long-term prognosis.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1203","session":"FLASH COM - Insuffisance rénale aiguë","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"VIGNERON Clara"},{"id":99447,"num":"A34658CB","reference":"FC-113","title":"A simplified algorithm to predict left ventricular systolic function in septic shock patients","formatedAuthors":"Clément BRAULT (1), Yoann ZERBIB (1), Julien MAIZEL (1), Michel SLAMA (1)
(1) CHU Amiens-Picardie, Amiens, FRANCE","contentIntroduction":"Septic cardiomyopathy (SCM) is characterized by a transient biventricular dysfunction with reduced contractility. Left ventricular (LV) ejection fraction (LVEF) is the conventional method to determine LV systolic function in septic shock, but is unhelpful to predict mortality. In contrast, the longitudinal strain (LVLS) might aid in early diagnosis of SCM, and was strongly associated with mortality. In this study, we developed an echocardiographic algorithm, using simple bedside parameters, to predict LVEF and LVLS in patients with septic shock.","contentPatientsMethods":"We included all consecutive patients admitted with septic shock (defined in accordance with the Sepsis-2 criteria) or developing a septic shock during the ICU stay. We measured septal and lateral mitral annular plane systolic excursion (MAPSE), septal and lateral mitral S-wave velocity, and the left ventricular longitudinal wall fractional shortening (LV-LWFS). We used a conditional inference tree method to build a stratification algorithm; recursive partitioning was used to stratify the population of interest into subgroups. The best predictor and the corresponding optimal cutoff value were calculated. Bonferroni correction for multiple testing was applied to univariate p values. The tree-building process continued as long as a predictor led to significantly different child nodes.","contentResultats":"We included 71 patients (males: 59%; mean ± SD age: 61 ± 15 years). We found that 31% and 73% had an impaired LV systolic function assessed by LVEF and LVLS, respectively. The septal MAPSE, with a threshold of 1.2 cm, was the best parameter to predict the LV systolic function (Figure 1). Other parameter (such as the S-wave or LV-LWFS) did not allow improving the algorithm’s performance. Septal MAPSE ≥1.2 cm predicted normal LVEF with near certainty. Conversely, septal MAPSE <1.2 cm almost always predicted impaired LVLS, while almost half patients remained with preserved LVEF.","contentDiscussion":"Septal MAPSE, used as the main parameter to predict LV systolic function, has several advantages. First, it only requires a simple M-mode measurement, available in all ultrasound devices including handheld machines. Second, MAPSE is easily recorded even in patients with poor acoustic window (including obese patients) because of the high echogenicity of the atrioventricular plane. Third, its reproducibility is excellent even in inexperienced users, and require only minimal training.","contentConclusion":"Septal MAPSE, easily measurable at bedside and with good reproducibility, might be useful to support clinicians in early detection of SCM, especially when strain is not available or feasible.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SLAMA Michel"},{"id":99448,"num":"A34508TG","reference":"FC-114","title":"An impaired global longitudinal strain at speckle tracking is associated with poorer haemodynamic condition irrespectively of the left ventricular ejection fraction during septic cardiomyopathy","formatedAuthors":"Thibaut GOBÉ (1), Simone CARELLI (1), Guillaume ROGER (1), Christopher LAI (1), Tài PHAM (1), Jean-Louis TEBOUL (1), Xavier MONNET (1)
(1) Hôpital de Bicêtre, Le Kremlin Bicetre, FRANCE","contentIntroduction":"Global Longitudinal Strain (GLS) is more sensitive than left ventricular ejection fraction (LVEF) to detect impaired contractility during septic cardiomyopathy. However, its evolution over time has been poorly described. Moreover, the clinical importance of an impaired GLS is unclear. In particular, the haemodynamic consequences of an impaired GLS per se have never been reported.","contentPatientsMethods":"In 61 adult patients with septic shock, we performed transthoracic echocardiography to measure LVEF and GLS with speckle tracking within the first 24 hours (day-0), at day-1, day-3 and on the day when vasopressors were stopped. Simultaneously, central venous oxygen saturation (ScvO2), blood lactate and cardiac index (PiCCO2 device) were assessed.","contentResultats":"Eleven patients were excluded for poor echogenicity or prone positioning at the time of inclusion. The prevalence of a low LVEF (<45%) was 36% at day-0, 39% at day-1, 38% at day-3 and 14% on the day of vasopressors weaning. At these time points, systolic arterial pressure was 118 [109 ; 127], 121 [116 ; 133], 123 [114 ; 132] and 130 [120 ; 134] mmHg, respectively. The prevalence of an impaired GLS (>-16%) was 70% at day-0, 72% at day-1, 75% at day-3 and 58% at vasopressors weaning. Pooling all time points, GLS was correlated with blood lactate (rho=0.369, 95% confidence interval: [0.213;0.506], p<0.0001), and ScvO2 (rho=-0.293 [-0.457;-0.110], p<0.0021).\n At each measurement time, we classified the cardiac status into three groups : normal LVEF and normal GLS (LVEFn-GLSn, n=40), normal LVEF and impaired GLS (LVEFn-GLSimpaired n=52) and low LVEF and impaired GLS (LVEFlow-GLSimpaired, n=36). Compared to the LVEFn-GLSn group, the LVEFn-GLSimpaired group exhibited a lower cardiac index (2.6 [2.3;3.1] vs. 3.1 [2.6;3.9] L/min/m2, p=0.03), a higher lactate level (1.7 [1.3;2.3] vs. 1.4 [1.0;2.1] mmol/L, p=0.04) and lower ScvO2 (67 [63;74] vs. 72 [67;78]%, p=0.02). In the LVEFlow-GLSimpaired group, cardiac index was lower (2.4 [2.2;2.8] vs. 2.6 [2.3;3.1] L/min/m2, p=0.03), lactate higher (2.8 [2.0;3.8] vs. 1.7 [1.3;2.3] mmol/L, p = 0.01) than in the LVEFn-GLSimpaired group and ScvO2 was not significantly different (69 [57;74] vs. 67 [63;74]%, p=0.76) (figure 1).","contentDiscussion":"","contentConclusion":"During septic cardiomyopathy, GLS remains impaired in a large proportion of patients when vasopressors are stopped. An impaired GLS is associated with lower cardiac index and poorer tissue oxygenation irrespectively of the value of LVEF. This suggests that an impaired GLS has clinical meaning per se. The study is ongoing.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GOBÉ Thibaut"},{"id":99449,"num":"A34521AH","reference":"FC-115","title":"Decrease in lactate level and norepinephrine dosage in the first 24 hours of resuscitation is strongly associated with survival in 502 patients with refractory shock","formatedAuthors":"Antonin HUGEROT (1), Raphaël CLERE-JEHL (1), Cédric SUBLON (1), Julien STEIN (1), Carlos GARIJO (1), Max GUILLOT (1), Jean-Etienne HERBRECHT (1), Ralf JANSSEN-LANGENSTEIN (1), Justine LEROUX (1), Yonatan PEREZ (1), Maleka SCHENCK-DHIF (1), Francis SCHNEIDER (1), Vincent CASTELAIN (1)
(1) Hôpitaux Universitaires de Strasbourg, Strasbourg, FRANCE","contentIntroduction":"To determine the prognostic impact of maximum norepinephrine dosage received in the first 24 hours following admission to the intensive care unit, regardless of indication, and to determine factors associated with in-ICU and in-hospital mortality","contentPatientsMethods":"All patients receiving norepinephrine in the first 24 hours after admission to our University Hospital intensive care unit between January 1, 2015 and January 1, 2020 were included, retrospectively. We collected for each patient the maximum dosage of norepinephrine and all diagnostic, clinical and biological parameters of interest. Univariate and multivariate inferential statistical analysis was performed.","contentResultats":"We included 2009 patients, mean age 66 years, 40% of whom were women, and presenting with septic shock in 53% (n= 1073). Mean SAPS II reached 59 ± 19 points. Mechanical ventilation and renal replacement therapy were required in 77% and 23%, respectively. Intra-ICU and intra-hospital mortality were 32% and 39%, respectively. The median maximum norepinephrine dosage received during the first 24 hours was 0.4 µg/kg/min (IQR 0.2-0.85). A significant increase in mortality was observed in uni- and multivariate analysis in patients who received more than 0.85 µg/kg/min of norepinephrine corresponding to the 3rd quartile distribution of maximum norepinephrine dosage, (in-ICU mortality 62%, p < 0.001). Among patients who received more than 0.85 µg/kg/min norepinephrine, defined as refractory shock, decreasing kinetics of lactate and norepinephrine dosage at 24 hours were found to be highly significantly and independently associated with patient survival (in-ICU mortality 43%). On the other hand, the need for extrarenal purification or the use of adrenaline were independently associated with excess mortality in this group.","contentDiscussion":"","contentConclusion":"In our study, the threshold of 0.85 µg/kg/min is an independent marker of mortality in patients admitted to the ICU and could be considered to define refractory shock, regardless of diagnosis. However, when dosages higher than this threshold are used, lactate level and norepinephrine doses rapid decrease are strongly associated with a better prognosis. These findings need to be confirmed by further work in other patient populations before being used in clinical practice.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HUGEROT Antonin"},{"id":99450,"num":"A33923RJ","reference":"FC-116","title":"Prehospital norepinephrine administration reduces 30-day mortality among septic shock patients","formatedAuthors":"Adèle HAJJAR (1), Romain JOUFFROY (1,8), Basile GILBERT (2), Jean Pierre TOURTIER (3), Emmanuel BLOCH-LAINE (4), Patrick ECOLLAN (5), Josiane BOULARAN (6), Vincent BOUNES (6), Benoit VIVIEN (8), Papa GUEYE (7)
(1) APHP - CHRU Ambroise Paré, Boulogne-Billancourt, FRANCE ; (2) Department of Emergency Medicine, SAMU 31, University Hospital of Toulouse, Toulouse, FRANCE ; (3) Paris Fire Brigade, Paris, FRANCE ; (4) Emergency Department, Cochin Hospital, Paris, France & Emergency Department, SMUR, Hôtel Dieu Hospital - Assistance Publique - Hôpitaux Paris, Paris, FRANCE ; (5) Intensive Care Unit, SMUR, Pitie Salpêtriere Hospital - Assistance Publique - Hôpitaux Paris, Paris, FRANCE ; (6) SAMU 31, Centre Hospitalier Intercommunal Castres-Mazamet, Castres, FRANCE ; (7) SAMU 972 University Hospital of Martinique, , Fort-De-France Martinique, FRANCE ; (8) Intensive Care Unit, Anaesthesiology, SAMU, Necker Enfants Malades Hospital, Assistance Publique - Hôpitaux Paris, Paris, FRANCE","contentIntroduction":"Despite differences in time of sepsis recognition, recent studies support that\n early initiation of norepinephrine in patients with septic shock (SS) improves outcome\n without adverse effects increase.\n This study aims to investigate the relationship between 30-day mortality in patients with SS\n and prehospital norepinephrine infusion in order to reach a mean blood pressure (MAP) > 65\n mmHg at the end of the prehospital stage.","contentPatientsMethods":"From April 06 th , 2016 to December 31 th , 2020, patients with SS requiring\n prehospital Mobile Intensive Care Unit intervention (MICU) were retrospectively analysed.\n To consider cofounders, propensity score method was used to assess the relationship between\n prehospital norepinephrine administration in order to reach a MAP > 65 mmHg at the end of\n the prehospital stage and 30-day mortality.","contentResultats":"Four hundred seventy-eight patients were retrospectively analysed, among which\n 309 patients (65%) were male. The mean age was 69 ± 15 years. Pulmonary, digestive, and\n urinary infections were suspected among 44%, 24% and 17% patients, respectively. One third\n of patients (n=143) received prehospital norepinephrine administration with a median dose of\n 1.0 [0.5-2.0] mg.h -1 , among which 84 (69%) were alive and 38 (31%) deceased on day 30\n after hospital-admission. 30-day overall mortality was 30%. Cox regression analysis after\n propensity score showed a significant association between prehospital norepinephrine\n administration and 30-day mortality: adjusted hazard ratio of 0.42 [0.25-0.70], p<10 -3 .\n Multivariate logistic regression of IPTW retrieved a significant decrease of 30-day mortality\n among prehospital norepinephrine group: ORa= 0.75 [0.70-0.79], p<10 -3 .","contentDiscussion":"","contentConclusion":"In this study, we report that prehospital norepinephrine infusion in order to reach\n a MAP > 65 mmHg at the end of the prehospital stage is associated with a decrease in 30-day\n mortality in patients with SS cared for by a MICU in the prehospital setting. Further\n prospective studies are needed to confirm that very early norepinephrine infusion allows to\n decrease septic shock mortality.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HAJJAR Adèle"},{"id":99451,"num":"A34486CL","reference":"FC-117","title":"Time for restauration of radial arterial pressure after a transient arm vascular occlusion correlates with outcome in critically ill patients: preliminary results of an observational study.","formatedAuthors":"Christopher LAI (1), Rui SHI (1), Jean-Louis TEBOUL (1), Francesca MORETTO (1), Laurent GUÉRIN (1), Monnet XAVIER (1)
(1) AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU 4 CORREVE, Inserm UMR S_999, FHU SEPSIS, CARMAS, Université Paris-Saclay, Le Kremlin-Bicêtre, FRANCE","contentIntroduction":"Impairment of vascular reactivity is one of the characteristics of septic shock and is associated with a poor outcome in critically ill patients. It can be assessed by the resaturation slope of the muscular tissue oxygen saturation after a transient vascular occlusion (TVO). Another means for assessing vascular reactivity might be to observe the time of the increase in radial arterial pressure after a TVO at the arm level.","contentPatientsMethods":"Mechanically ventilated patients hospitalized in intensive care unit and equipped with a radial artery catheter were prospectively included. A brachial cuff was rapidly inflated to induce a transient arterial stop-flow. Arterial pressure thus decreased down to the level of mean systemic pressure (Pmsarm). After 60 seconds of TVO, the cuff was abruptly deflated and time to return from Pmsarm to baseline systolic arterial pressure was measured (Trevasc).","contentResultats":"We included 41 patients, among whom 19 (46%) where in shock, including 13 (32%) septic shock, 10 (24%) had acute respiratory distress syndrome and 9 (22%) were intubated for neurological impairment. Norepinephrine was infused in 25 (61%) patients (0.3 [0.17-1.10] μg/kg/min). Measurements were obtained 3 (2-6) days after onset of mechanical ventilation or vasopressors infusion. Mean arterial pressure was 84±12 mmHg, Pmsarm was 29±9 mmHg, central venous pressure was 12±4 mmHg and the (Pmsarm-CVP) gradient was 16±8 mmHg, with no difference between patients with or without shock. In the whole population, Trevasc was 26 (20-33) sec. It was significantly increased in patients with shock compared to those without shock (33±18 vs. 23±10 sec., respectively, p=0.028). Among patients with shock, Trevasc was longer in patients with septic shock than in the other ones (33 (28-44) vs. 16 (9-30) sec., respectively, p=0.048). Trevasc was significantly increased in the 21 (51%) patients who died (11 patients with shock) compared to survivors (33±19 vs. 23±10 sec., respectively, p=0.037).","contentDiscussion":"","contentConclusion":"In critically ill patients under mechanical ventilation, Trevasc was increased in patients with shock compared to patients without shock, especially in septic shock patients. Trevasc was also higher in non-survivors. This new variable might indicate vasoreactivity at bedside and, as such, be associated with severity and mortality. More data are needed to confirm these preliminary results and inclusions are ongoing.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAI Christopher"},{"id":99452,"num":"A34354JL","reference":"FC-118","title":"Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients","formatedAuthors":"Jean-Rémi LAVILLEGRAND (1), Lisa RAIA (1), Tomas URBINA (1), Geoffroy HARIRI (1), Paul GABARRE (1), Vincent BONNY (1), Naike BIGÉ (1), Jean Luc BAUDEL (1), Arnaud BRUNEEL (2), Thierry DUPRE (1), Bertrand GUIDET (1), Eric MAURY (1), Hafid AIT OUFELLA (1)
(1) APHP-CHU Saint Antoine, Paris, FRANCE ; (2) APHP-CHU Bichat, Paris, FRANCE","contentIntroduction":"Vitamin C has potential protective effects through antioxidant and anti-inflammatory properties. However, the effect of vitamin C supplementation on microvascular function and peripheral tissue perfusion in human sepsis remains unknown. We aimed to determine vitamin C effect on microvascular endothelial dysfunction and peripheral tissue perfusion in septic shock patients.","contentPatientsMethods":"Patients with septic shock were prospectively included after initial resuscitation. Bedside peripheral tissue perfusion and skin microvascular reactivity in response to acetylcholine iontophoresis in the forearm area were measured before and 1 h after intravenous vitamin C supplementation (40 mg/kg). Norepinephrine dose was not modified during the studied period.","contentResultats":"We included 30 patients with septic shock. SOFA score was 11 [8-14], SAPS II was 66 [54-79], and in-hospital mortality was 33%. Half of these patients had vitamin C deficiency at inclusion. Vitamin C supplementation strongly improved microvascular reactivity (AUC 2263 [430-4246] vs 5362 [1744-10585] UI, p = 0.0004). In addition, vitamin C supplementation improved mottling score (p = 0.06), finger-tip (p = 0.0003) and knee capillary refill time (3.7 [2.6-5.5] vs 2.9 [1.9-4.7] s, p < 0.0001), as well as and central-to-periphery temperature gradient (6.1 [4.9-7.4] vs 4.6 [3.4-7.0] °C, p < 0.0001). The beneficial effects of vitamin C were observed both in patients with or without vitamin C deficiency.","contentDiscussion":"","contentConclusion":"In septic shock patients being resuscitated, vitamin C supplementation improved peripheral tissue perfusion and microvascular reactivity whatever plasma levels of vitamin C.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAVILLEGRAND Jean-Rémi"},{"id":99453,"num":"A34740FM","reference":"FC-119","title":"Noradrenaline dose change-related effects on mean arterial pressure: preliminary results from the NoVaMAP study","formatedAuthors":"Francesca MORETTO (1), Rui SHI (1), Jean-Louis TEBOUL (1), Arthur PAVOT (1), Christopher LAI (1), Nicolas FAGE (1), Tài PHAM (1), Xavier MONNET (1)
(1) Université Paris-Saclay, AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Le Kremlin-Bicêtre, FRANCE","contentIntroduction":"Responsiveness to norepinephrine (NE) dose change in terms of mean arterial pressure (MAP) change is highly variable among patients with acute circulatory failure. This preliminary study aimed to investigate the factors influencing the pharmacodynamic effect of NE on MAP in critically ill patients.","contentPatientsMethods":"This monocentric, observational, prospective study was conducted in patients with acute circulatory failure requiring NE and invasive arterial pressure monitoring. To characterize the responsiveness of MAP to NE change, the maximal amplitude of MAP change over the amplitude of change in the NE (deltaMAPmax/deltaNE) was calculated.","contentResultats":"From January to July 2021, 29 patients presenting 86 occurrences of change in the NE dose, including 55 dose-increases and 31 dose-decreases, were included. The most common origin of shock was sepsis in 59 (69%) cases, followed by hypovolemic/hemorrhagic shock in 16 (18%) cases and non-septic vasoplegia in 11 (13%) cases. Septic shock was characterized by significantly lower baseline values of MAP (66 [58-86] vs. 82 [71-103] mmHg) and of diastolic arterial pressure (50 [44-64] vs. 64 [55-78] mmHg) and by a larger amplitude of the change in NE dose (0.08 [0.05-0.12] vs. 0.04 [0.03-0.06] µg/kg/min). DeltaMAPmax/deltaNE was significantly lower in septic shock than in hypovolemic/hemorrhagic shock or non-septic vasoplegia (315 [161-590] vs. 575 [401-776] vs. 446 [336-1119] mmHg/µg/kg/min, respectively, p=0.03). At multiple linear regression analysis, preexisting hypertension, body temperature at the study time and shock etiology were associated with deltaMAPmax/deltaNE (p=0.002). In septic shock patients, body temperature and C-reactive protein levels independently influenced deltaMAPmax/deltaNE (p=0.003).","contentDiscussion":"","contentConclusion":"Septic shock is characterized by lower vascular reactivity compared to other shock etiologies and MAP responsiveness to NE change is not identical to other types of distributive shocks. The results of this ongoing study will be entered in a model of artificial intelligence with the aim of adapting the dose of NE required to reach an individualized target level of MAP.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1204","session":"FLASH COM - Etat de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MORETTO Francesca"},{"id":99454,"num":"A34654AG","reference":"FC-120","title":"Is precariousness a risk factor for COVID-19 mortality in intensive care units ?","formatedAuthors":"Adrien GILLIBERT (1), Laurent LAINE (1)
(1) Delafontaine, Paris, FRANCE","contentIntroduction":"During the SARS-CoV-2 pandemic, the first wave overwhelmed hospitals in Paris area (Ile-de-France) with a variable impact depending on the territory. Several studies highlighted variable ICU mortality rates during COVID-19 surges across territories (10 to 60%) with higher rates in those most affected by poverty1,2. We assessed the impact of precariousness, as an independent risk factor, on mortality linked to Covid-19 between ICUs at Delafontaine hospital and Ambroise Paré hospital","contentPatientsMethods":"We carry out a retrospective observational cohort study of consecutive ICU patients aged ≥ 18 years admitted at Delafontaine and Ambroise Paré hospitals during the first wave of the Covid-19 outbreak in order to compare mortality rates according to predefined risk factors (age, diabetes, arterial hypertension, BMI, active solid or haematological cancer, IGS2, poverty rate at the threshold of 60% (%) according to the island grouped for statistical information (IRIS)37 of the patient, invasive ventilation or not) that include precariousness.","contentResultats":"We found a difference for mortality in the two groups (p = 0,033) and with the univariate analysis the poverty rate was a risk factor for mortality at 90 days (p = 0,04). But we could not find a statistical relation between deprivation and mortality at 90 days in Covid-19 in intensive care in multivariate analysis.","contentDiscussion":"","contentConclusion":"Despite lake of significative statistical relationship between precariousness and covid-19 mortality in intensive care, it seems we could find correlation between importance of precariousness and mortality. We should realise a prospective study with more important population to find a relationship between deprivation and mortality at Covid-19 in intensive care.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1. Quenot, Jean-Pierre et al. “Influence of deprivation on initial severity and prognosis of patients admitted to the ICU: the prospective, multicentre, observational IVOIRE cohort study.” Annals of intensive care vol. 10,1 20. 11 Feb. 2020, doi:10.1186/s","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"2. Rahi, Mayda et al. “Sociodemographic characteristics and transmission risk factors in patients hospitalized for COVID-19 before and during the lockdown in France.” BMC infectious diseases vol. 21,1 812. 13 Aug. 2021, doi:10.1186/s12879-021-06419-7","presentateur":"GILLIBERT Adrien"},{"id":99455,"num":"A34445VP","reference":"FC-121","title":"Management of a massive inflow of patients in a very large cluster of covid-19 cases","formatedAuthors":"Valentin POINTURIER (1), Antoine POIDEVIN (1), Samuel DEGOUL (1), Edouard VIROT (1), Yoganaden MOOTIEN (1), Luis PINTO (1), Cyrille MATHIEN (1), Guylaine LABRO (1), Yannick RABOUEL (1), Arnaud ETIENNE (1), Khaldoun KUTEIFAN (1)
(1) Hôpital Emile Muller, Mulhouse, FRANCE","contentIntroduction":"Our general tertiary hospital had to face an unprecedented wave of respiratory distress in early 2020 that quickly overwhelmed its 40 ICU beds. The aim of this study is to report on ICU admission process and in-flow management at time of Covid-19 outbreak.","contentPatientsMethods":"We conducted a retrospective analysis of every consecutive patient requiring the advice of the intensivist team between March 2 and May 1, 2020 from a call register filled prospectively on daily basis.","contentResultats":"Local ICU capacities have more than doubled (92 beds) thanks to the deprogramming of the scheduled surgical activity and the deployment of a military mobile hospital.\n Medical ICU physician on duty centralized all calls for Covid-19 admission. Priority was given to patient requiring immediate intubation. The others were placed on a waiting list according to their severity and expected prognosis based on their comorbidities, their frailty and their age until a ventilator was available.\n At the peak, 46 patients required the advice of the intensivist daily. A total of 591 patients were proposed for ICU admission. 75% were acute respiratory distress due to severe Covid-19, other were medical (14%) and surgical (11%) non covid related situations. ICU admission was decided for 370 patients. Mean age was 62 years (±12), 69% were male. The most serious patients and those with contraindications to transfer were kept in local ICU (154 patients). 244 patients were transferred to France, Germany, Switzerland, and Luxembourg representing more than one third of all French transfers of the Covid-19 first wave.\n The patients managed in standard ward were older (mean age : 69 years (±12) ) and had more significant cardiovascular diseases (12,7% vs 5%), malignant tumors (10,5% vs 3,1%) and hematological diseases (8,2% vs 4,7%).","contentDiscussion":"","contentConclusion":"In situation of high tension on ICU capacities, priority must be given to increasing resources and optimizing means. The establishment of triage rules respecting the ethical principles of equality, beneficence, and transparency guarantees equitable access to intensive care and maximization of the number of lives saved.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"POINTURIER Valentin"},{"id":99456,"num":"A34383FM","reference":"FC-122","title":"Evaluation of communication training in paediatric intensive care","formatedAuthors":"Floriane DUCERT (1), Rachel OHNOUNA (1), Noémie VANEL (1), Céline GRIMALDI (1), Cesar RONCIN (1), Fabrice MICHEL (1)
(1) Hopital Timone 2, Marseille, FRANCE","contentIntroduction":"Communication with patients requires interpersonal skills and is a challenge for physicians, especially in paediatric critical care units. The need for good communication contrasts with the lack of training in communication skills in medical studies, and there is little experience in the literature of evaluating communication with families training in paediatric critical care. The main objective of this study was to heteroevaluate the impact of communication training for residents in a paediatric intensive care unit.","contentPatientsMethods":"14 residents were evaluated on their performance in communicating with families through video recordings of simulated breaking bad news to parents, before and after a 2-day training in communication with families including theoretical teaching and situational practice in relational simulation. The skills were also evaluated 3 month after the training to measure maintenance of acquisition over time. Residents were confronted to 3 standardized situations in predetermined order, different for each of them. The ‘’modified Breaking Bad News Assessment Scale’’ (mBAS) was used as the evaluation tool scored by resident an not involved in the training, and analyzing the videos in a totally random order. The duration of interviews, speaking and silence times were recorded. Self-assessment was also performed using the ‘’Breaking Bad News’’ and ‘’Cungi and Rey’’ scales scored after each session.","contentResultats":"Both self-assessment scores showed important and significant improvement of the participants after the training, and maintenance of acquisitions over time. The global mBAS score decrease (corresponding to skills improvement) non-significantly, immediatly after training (55.8±8.1 vs. 49.0±8.0; p=0.071), but there was a significant improvement in two of the five score domains (A : setting the scene, C : eliciting concerns). Stress of residents after interviews decreased non significatly between the 3 measures (5,0±1,7 ;4,4±2,1 ;3,7±1 ;p=0,214). Duration of interviews and silence did not vary significantly.","contentDiscussion":"","contentConclusion":"Our study showed that training in communication with parents in the paediatric intensive care unit resulted in an improvement in the resident’s autoevaluation. This effect was less pronounced during heteroevaluation, which should encourage teachers to evaluate their training by objective methods.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MICHEL Fabrice"},{"id":99457,"num":"A34558mz","reference":"FC-123","title":"Mental health problems among Tunisian healthcare workers in the second year of Covid-19 pandemic","formatedAuthors":"Marwa ZGHIDI (1), Imen BEN SAIDA (1,2), Dhouha HAMDI (1), Rihab BOUBTANE (1), Mohamed BOUSSARSAR (1,2)
(1) Farhat Hached University Hospital, Medical Intensive Care Unit, Sousse,TUNISIA, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, Sousse, Tunisia, Sousse, TUNISIE","contentIntroduction":"The fear to contaminate and beingcontaminated, the quality of preparedness, the availability of personal protection equipment (EPI), diagnostic and therapeutic blur of an emergent disease and patients’ severity leading to high workload have added a burden of acute emotional stress in healthcare workers.\n The aim was to evaluate the impact of Covid-19 pandemic on healthcare workers mental health and identify factors associated with adverse mental outcomes.","contentPatientsMethods":"It is a cross-sectional study conducted in critical care and emergency departments of 3 hospitals (Hached;Sahloul and Military hospitalof Instruction of Tunis) from January 18, 2021, to March 13, 2021.Mental health outcomes: depression, anxiety, stress,post-traumatic stress disorder and burnout were assessed by depression anxiety stress scales (DASS), Impact of event scale revised(IES-r) and Maslach Burn out Inventory (MBI), respectively.Multivariate logistic regression analysis was performed to identify factors associated with those adverse mental health outcomes.","contentResultats":"One hundred and ten healthcare workers filled the questionnaire with a response rate at 86.6%.Respondents characteristics’ were: median age, 32 [28-37] years ;female 68(61.8%) ;nurses 57(51.8%) ; 63(57.3%) worked in emergency departments.Fifty-two respondents(47.3%) had been contaminated by the SARS COV2. 88.2% of the respondentsreported a feelingof fear of personal and family physical safety,74.5% felt an increased work overloadand 72.7% confirmed a poor working conditions. 43 respondents (43.6%) were considering quitting their profession because of severe psychological distress.\n 48.2%, 42.7% and48.98% of respondents had respectively severe stress, severe anxiety and severe burnout.49.1% of participants had probable PTSD according to IES-r score.\n On the multivariate regression, female sex (OR, 9.7;CI [2.5-36.7]; p<0.001), age (OR,0.083; IC[0.013-0.537]; p=0.009) , work overload (OR,5.6; IC[1.3-23.7]; p=0.018), were factors associated with stress.\n Age (OR,0.6; IC[0.5-0.87]; p=0.000), work overload (OR,29; IC[3-63]; p=0.002); change of work location(OR,11.3; IC[1.4-88.7]; p=0.021); poor work conditions(OR,20.7; IC[12-66]; p<0.001) were associated with anxiety.\n Lack of psychological support (OR,5.8; IC[2-16]; p<0.001) was the only risk factor associated with depression.\n Age (OR,0.6; IC[0.4-0.73]; p<0.001); fear of personal and family safety(OR,7.2; IC[1.1-15]; p<0.001); working with suspected or confirmed patients with COVID-19 (OR,29; IC[2-69]; p=0.009) were factors independently associated with PTSD.\n Female sex (OR,1.1; IC[1.04-1.2]; p=0.003), poor work conditions(OR,3.5; IC[1.7-4.6]; p=0.047) were predictors of Burnout.","contentDiscussion":"","contentConclusion":"The current study highlights that health care workers are at high risk for psychological distress during the covid-19 outbreak. Early psychological interventions may be beneficial","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ZGHIDI Marwa"},{"id":99458,"num":"A34611VD","reference":"FC-124","title":"Prevalence of post-traumatic stress disorder in intensive care workers","formatedAuthors":"Victoire DELTOUR (1,3), Alexandra LAURENT (1,2), Anne-Laure POUJOL (3,4)
(1) Université de Bourgogne Franche-Comté, Psy-DREPI EA 7458, Dijon, FRANCE ; (2) Service de réanimation chirurgicale, CHU Dijon, Dijon, FRANCE ; (3) Ecole de Psychologues Praticiens , Paris , FRANCE ; (4) Service de réanimation chirurgicale polyvalente, La pitié Salpêtrière, Paris, FRANCE","contentIntroduction":"Working in intensive care unit confronts professionals with extreme and unpredictable situations that have a traumatic dimension and constitute a risk of post-traumatic stress disorder (PTSD). ?Since 2019 this extreme context has been accentuated by unprecedented epidemic waves. we will present a systematic review to better identify the traumatic impact of ICU on healthcare and associated factors before and during the health crisis.","contentPatientsMethods":"We used Pubmed; Science direct and Ovid (APA) databases to identify all quantitative, qualitative and mixed studies examining PTSD in Intensive care workers between 2009 and 2022.","contentResultats":"Of the 704 articles identified, only 8 met our inclusion criteria. 4 studies that were conducted before the COVID period showed that 3.3% to 18.2% of the intensive care workers surveyed had symptoms of PTSD. The associated risk factors were life-threatening emergencies; exposure to death; management of organ and body donations; and situations experienced by caregivers as therapeutic overkill. Individual factors such as personality also appear to play a role in the development of traumatic symptomatology (Cho et Kang 2017). 4 studies conducted during the COVID period show a significant increase in the prevalence of trauma among Intensive care workers, with between 16% and 73.3% showing traumatic symptoms. The already potentially traumatic factors of ICU were exacerbated and others specific to the crisis increased this risk (Carmassi et al. 2022; Laurent et al. 2022). Feeling safe in one's department, supported by one's team, and having sufficient material and human backup seemed to be protective factors (Heesakkers et al. 2021).","contentDiscussion":"","contentConclusion":"Intensive care workers seem to be particularly at risk of developing PTSD, and this has increased during the health crisis period. However, there are few studies on this subject and they deserve to be developed in order to propose prevention and adapted care devices.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DELTOUR Victoire"},{"id":99459,"num":"A34422FP","reference":"FC-125","title":"A qualitative study of reinforcement workers’ perceptions and experiences of working in intensive care during the COVID-19 pandemic: a PsyCOVID-ICU substudy","formatedAuthors":"Florian PERRAUD (1), Fiona ECARNOT (2,3), Mélanie LOISEAU (4), Alexandra LAURENT (5,6), Alicia FOURNIER (5), Florent LHEUREUX (7), Christine BINQUET (8), Jean-Philippe RIGAUD (9,10), Nicolas MEUNIER-BEILLARD (11,12), Jean-Pierre QUENOT (11,13,14,15)
(1) University Hospital Dijon, and Université de Bourgogne Franche-Comté, Dijon, France, Dijon, FRANCE ; (2) Department of Cardiology, University Hospital Besançon, Besançon, FRANCE ; (3) EA3920, University of Burgundy-Franche-Comté, Besaançon, FRANCE ; (4) Service de Médecine Légale, University Hospital Dijon ; Cellule d’Urgence Médico-Psychologique de Bourgogne Franche-Comté, Dijon, FRANCE ; (5) Laboratoire de Psychologie : Dynamiques Relationnelles Et Processus Identitaires (PsyDREPI), Université de Bourgogne Franche-Comté, Dijon, FRANCE ; (6) Department of Anaesthesiology and Critical Care Medicine, University Hospital Dijon, Dijon, FRANCE ; (7) Laboratoire de Psychologie, University of Burgundy-Franche-Comté, Besançon, FRANCE ; (8) Inserm CIC1432, module Épidémiologie Clinique (CIC-EC)- CHU Dijon-Bourgogne, UFR des Sciences de Santé, Dijon, FRANCE ; (9) Service de Médecine Intensive-Réanimation, Hospital Centre of Dieppe, Dieppe, FRANCE ; (10) Espace de Réflexion Éthique de Normandie, Université de Caen, Caen, FRANCE ; (11) CIC 1432, Clinical Epidemiology, University of Burgundy, Dijon, FRANCE ; (12) Direction de la Recherche Clinique et de l’Innovation, University Hospital Dijon, Dijon, FRANCE ; (13) Service de Médecine Intensive-Réanimation, University Hospital Dijon, Dijon, FRANCE ; (14) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (15) Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Besançon, FRANCE","contentIntroduction":"During the COVID pandemic, many hospitals had to mobilize reinforcement healthcare workers (HCW), especially in intensive care units (ICUs). We investigated the perceptions and experiences of reinforcement workers deployed to ICUs, and the impact of deployment on their personal and professional lives.","contentPatientsMethods":"For this qualitative study, a random sample of reinforcement workers was drawn from 4 centres participating in the larger PsyCOVID-ICU study. These HCW worked in the intensive care unit as support staff during either of the two waves of 2020 (March to May 2020 (wave 1) or September to November 2020 (wave 2)) in any of the four participating centres. Individual semi-structured interviews were held by telephone, recorded, transcribed and analyzed by thematic analysis.","contentResultats":"Thirty interviews were performed from April to May 2021 (22 nurses, 2 anesthesiology nurses, 6 nurses’ aides). Average age was 36.8 ± 9.5 years ; 7 participants had no ICU experience. Four major themes emerged, namely: (1) Difficulties with integration, especially for those with no ICU experience; (2) lack of training; (3) difficulties with management, notably a feeling of insufficient communication; (4) Mental distress relating to the unusual work and fear of contaminating their entourage.","contentDiscussion":"","contentConclusion":"HCWs deployed as reinforcements to ICUs at the height of the pandemic had a unique experience of the crisis, and identified important gaps in organisation and preparation. They also suffered from a marked lack of training, given the stakes in the management of critically ill patients in the ICU.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PERRAUD Florian"},{"id":99460,"num":"A34511GM","reference":"FC-126","title":"Direct OptimizatioN of cOmmunicaTion uSing PersonAlized Multimodal feedback between investigators to increase efficiency (DO NOT SPAM study)","formatedAuthors":"Grégoire MULLER (1,2), Elsa TAVERNIER (3,4), Marie LECLERC (5), Thierry BOULAIN (1,2), Stephan EHRMANN (6)
(1) Centre Hospitalier Régional d'Orléans, Orléans, FRANCE ; (2) CRICS-TriggerSEP F-CRIN research network, Tours, FRANCE ; (3) Clinical Investigation Center, INSERM 1415, CHRU Tours, Tours, FRANCE ; (4) Methods in Patients-Centered Outcomes and Health Research, INSERM UMR 1246, Nantes, FRANCE ; (5) Délégation à la Recherche Clinique et à l’Innovation, CHRU Tours, Tours, FRANCE ; (6) Médecine Intensive Réanimation, CIC 1415, CRICS-TriggerSEP F-CRIN research network and Centre d'étude des Pathologies Respiratoires, INSERM U1100, Université de Tours, Centre Hospitalier Régional Universitaire de Tours, Tours, FRANCE","contentIntroduction":"Only few clinical trials are completed in the expected timeframe, in part because of low inclusion rates. The specific context of “emergency trials” (short inclusion timeframes, very selective criterion) aside of time pressure associated with critical illness represents an extra challenge. Studies evaluating means to improve trial recruitment were performed outside of the ICU setting and aimed to increase the rate of patient consent rather than targeting investigator motivation. We hypothesize that an optimized communication strategy targeted at increasing investigator motivation may significantly improve trial recruitment.","contentPatientsMethods":"Study centres participating in the EVERDAC trial (evaluating early vs differed arterial catheter in ICU patients with acute circulatory failure, NCT03680963),[1] were randomized between two communication strategies: conventional communication or upgraded communication strategy (intervention) including personalized computer-generated emails of congratulations for inclusions according to inclusion rate. The primary outcome was the number of patients included in the EVERDAC trial 12 months after centre opening, analysed in a quasi-Poisson regression considering the number of ICU beds available in the unit as an offset.","contentResultats":"264 patients were included in the EVERDAC study in the nine participating centres, 119 from intervention centres (median 28.5 [18.0;46.9]), 145 from conventional centres (median 23.0 [7.0;25.0] (RR 0.53 [0.11;2.34], p=0.42, Figure 1). Respectively 115 and 145 emails were addressed to the investigator with respectively 13.0 [13.0; 14.0] and 8.0 [8.0;10.0] recipients in carbon copy (coinvestigators and study team).","contentDiscussion":"Our study failed to demonstrate that an optimized communication strategy could improve inclusion rate. First our study may be underpowered. Secondly, one large centre with no inclusion randomized to intervention and smaller centre which made by far most of the trial inclusions randomized to the control group, may represent outliers significantly impacting overall results. One could argue these centres would have included the same inclusion rate whatever the communication strategy applied (ie, our communication strategy may improve inclusions in centres with middle rate of inclusion). However, results were not modified when excluding those outlier centres from analysis (RR 0.6 [0.23;2.34]). Thirdly, the number of emails sent could have a negative effect on inclusions.","contentConclusion":"This study failed to demonstrate a benefit of an email based optimized communication strategy between the study coordinator and site investigators and staff on trial inclusion rate in the ICU.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1205","session":"FLASH COM - Du patient au soignant","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Muller G, BMJ Open. 2021;11:e044719","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MULLER Grégoire"},{"id":99461,"num":"A34481CT","reference":"FC-127","title":"Epidemiology of people living with HIV admitted to an ICU of the Caribbean region between 2015 and 2019.","formatedAuthors":"Célia TEISSEDRE (1), Michel CARLES (1), Isabelle LAMAURY (1), Benoit TRESSIERES (1), Bénédicte MELOT (1)
(1) CHU de la Guadeloupe, Les Abymes, GUADELOUPE","contentIntroduction":"People leaving with HIV (PLWHIV) from the Caribbean, due to the geographical and historical situation of this region, have very specific epidemiological characteristics, including a higher prevalence compared to other regions. The primary objective of this work was to describe the characteristics of PLWHIV treated in the ICU of our hospital to improve their care. The secondary objectives were to study factors associated to prognosis and assess the impact of HIV on ICU morbidity and mortality.","contentPatientsMethods":"We included all patients treated in the ICU of our hospital between January 2015 and December 2019 with the main or associated diagnosis “HIV” during their hospitalization. We first carried out a descriptive analysis using paper and computer files. We then performed a bivariate and multivariate analysis to study the variables associated with mortality in PLWHIV and then to compare the prognosis in intensive care, at 1 month and at one year in PLWHIV versus non-HIV, adjusted for the other variables.","contentResultats":"A total 114 PLWHIV and 228 patients without HIV were analyzed, i.e. an average of 23 PLWHIV per year, including 9 patients diagnosed at the time of their admission to the ICU, and 2 with a \"fortuitous\" diagnosis. The median age was 54 years old, the sex ratio 2, the median CD4 count was 218/ mm3 and the median viral load 185 copies, 1/4 had co-infection with hepatitis B, 81% had at least 1 opportunistic infection, 1/3 had a renal replacement therapy (RRT), half a vasopressor therapy, 3/4 mechanical ventilation. The mortality in the ICU was 31% (Table). PLWHIV were significantly more ventilated, on vasopressor therapy, and on RRT than non-HIV patients, and variables associated to higher ICU mortality in PLWHIV were intubation, RRT, vasopressor therapy, and single hospitalizations. However, mortality in ICU, at 1 month and 1 year, although slightly higher in PLWHIV didn't vary significantly.","contentDiscussion":"","contentConclusion":"PLWHIV hospitalized in the ICU of our hospital are frequent, more severe and require heavier care, compared to non-HIV patients. Factors related to the poor prognosis, like diagnosis delay due to HIV lack of knowledge, should be assessed. Due to the large number of PLWHIV admitted to the ICU (2 per month) in this area, specific approaches should be implemented : adaptation of human resourcees, infectious disease referent, specific and regular training of ICU physicians and paramedics to increase their skills regarding HIV specific aspects, in order to improve PLWHIV ICU prognosis.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TEISSEDRE Célia"},{"id":99462,"num":"A34614AP","reference":"FC-128","title":"Effect of antibiotics on catheter associated urinary tract infections in the ICU : A non inferiority retrospective trial","formatedAuthors":"Arthur PONCELET (1), Charlotte MICHEL (1), Maya HITES (1), Zoé PLETSCHETTE (1), Delphine MARTINY (1), Jacques CRÉTEUR (1), Frédérique JACOBS (1), David GRIMALDI (1)
(1) CUB Erasme - ULB, Bruxelles, BELGIQUE","contentIntroduction":"Catheter associated urinary tract infections (CAUTI) are the most frequent nosocomial infections, although rarely severe. In this setting the benefit/risk ratio of antibiotic therapy is unclear since overconsumption leads to antimicrobial resistance.Catheter associated asymptomatic bacteriuria should not be treated but distinction between asymptomatic bacteriuria and urinary infection is not easily made in ICU patients.\n We therefore hypothesized that the abstention of treatment of positive urine cultures associated with systemic signs of inflammation is not related with an increased sepsis occurrence in the following 7 days.","contentPatientsMethods":"Comparative retrospective monocentric study with a non inferiority design.\n Patients hospitalized between 2012 and 2018 for at least 48h in the ICU, with a bladder catheter and a positive urinary culture presenting fever (>38°C) or a CRP level above 100mg/l were included.\n Exclusion criteria were pregnancy, kidney transplant recipients, planned urological surgery, neutropenia, bacteriemic urinary tract infection the day of inclusion, other source of infection requiring antibiotics for which the urinary bacteria was susceptible or septic shock.\n Based on a previous study we expected a sepsis occurrence of 10%. To provide a power of 80% with a non inferiority margin of 10% we planned to include 112 patients in each group.","contentResultats":"Among 222 included patients, 100(45%) received antimicrobial therapy and 122(55%) did not. Groups were comparable in terms of age, sex, SAPS II score and co-morbidities. SOFA score the day of inclusion was higher in the groups who received antibiotics (median 4 versus 3 p=0,004). Escherichia Coli (50,4%), was the most frequent bacteria identified. Amoxicillin-clavulanic acid (42%), piperacillin/tazobactam (19%) and ciprofloxacin (16%) were the most prescribed antibiotics with a median duration of 5 days. Sepsis occurrence 7 days after the positive urinary culture were similar between the two groups (treated: 7% no treatment : 1,6% p=0,089). Moreover we found no difference between groups in terms of mortality (6% versus 1,6% p=0,08) or bacteremia (2% versus 2,4%p=0,671).","contentDiscussion":"","contentConclusion":"Absence of antibiotic treatment for urinary catheter associated positive culture and inflammatory syndrome in ICU patients was not associated with an increase in sepsis occurrence the next 7 days following the urinary culture. Further studies are needed to better define the indication of antibiotic treatment for CAUTI in ICU setting.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PONCELET Arthur"},{"id":99463,"num":"A34334sb","reference":"FC-129","title":"Coagulase-negative staphylococcus in intensive care unit.","formatedAuthors":"Sabah BENHAMZA (1,2), Badreddine ATAK (1,2), Mohamed LAZRAQ (1,2), Youssef MILOUDI (1,2), Abdelhak BENSAID (1,2), Najib EL HARRAR (1,2)
(1) Hôpital 20 Août 1953, CHUIR , Casablanca, MAROC ; (2) Université Hassan II, faculté de médecine et de pharmacie, Casablanca, MAROC","contentIntroduction":"Staphylococci are one of the most incriminated pathogens in human infections (1), in recent years there has been the emergence of resistant strains, especially coagulase negative (SCN). Our objective was to evaluate the incidence of SCN in a general intensive care unit and to study their sensitivity to antibiotics.","contentPatientsMethods":"retrospective study over 4 years conducted in the intensive care unit of the August 20 hospital. The patients included have at least one bacteriological sample positive for staphylococcus. Demographic, epidemiological, bacteriological, therapeutic and evolutionary data were analyzed and then compared in an SCN group.","contentResultats":"74 patients were included (mean age 44 ± 19.18 years, 54 men and 20 women). The incidence of SCN was 5.50%: 66% in the blood culture (n=58) and 34% in the catheter. 78.37% of patients were admitted to the intensive care unit from the emergency reception service (SAU). The average length of hospitalization was 18.52 days ± 14.22 days. The methicillin resistance rate was 43%. On the other hand, vancomycin and teicoplanin were effective. 23 patients were treated with anti-staphylococcal antibiotic therapy, 51 did not receive it, there was no statistically significant difference between these two groups of patients in terms of mortality (p=0.45). The most common cause of death was septic shock with no significant difference between the two treated and untreated groups.","contentDiscussion":"","contentConclusion":"the incidence of CNS remains low but their mortality is worrying. 43% of SCNs are resistant to methicillin. Glycopeptides have always been considered effective in the treatment of staphylococcal infections. Except that in recent years we have seen the appearance of cases of resistance of SCNs to these glycopeptides.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1- BILAL AHMAD MIR1, Dr. SRIKANTH. Prevalence and antimicrobial susceptibility of methicillin resistant staphylococcus aureus and coagulase-negative staphylococci in a tertiary care hospital. Asian J Pharm Clin Res, Vol 6, Suppl 3, 2013, 231-234","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MILOUDI Youssef"},{"id":99464,"num":"A34414SF","reference":"FC-130","title":"Exploring blood stream infection incidence in ICU patients treated by Therapeutic plasma exchange-A retrospective multicenter study","formatedAuthors":"Sofiane FODIL (2), Julien MAYAUX (3), Geoffroy HARIRI (3), Jean-Rémi LAVILLEGRAND (2), Bertrand GUIDET (2), Eric MAURY (2), Elie AZOULAY (1), Alexandre DEMOULE (3), Eric MARIOTTE (1), Hafid AIT-OUFELLA (2)
(1) Hôpital Saint-Louis, Paris, FRANCE ; (2) Hôpital Saint-Antoine, Paris, FRANCE ; (3) Hôpital de la Pitié-Salpêtrière, Paris, FRANCE","contentIntroduction":"Therapeutic plasma exchange (TPE) is a technique which separates out plasma from other components of blood. The plasma is removed and replaced with a surrogate solution(1). TPE has immunosuppressive impact which may increase the risk for infectious complications(2). However, the incidence of infections following TPE in ICU patients remains poorly investigated.","contentPatientsMethods":"We conducted a retrospective cohort study including patients treated by plasma exchange in the medical ICU of three tertiary teaching hospital in Paris, France (Saint-Antoine, Saint-Louis et Pitié-Salpétrière), between January 1st 2010 and December 31th 2019. Clinical, biological and microbiological parameters were collected with a focus on bloodstream infection (BSI).","contentResultats":"Overall, 264 patients were included with 5 (3-7) plasma exchange procedures. Median SOFA at admission was 5 (2-6) and ICU mortality was low (8%). The median age was 48 (34-63) years old, mainly women (59%) with a BMI at 25 (22-29). The main indications for TPE were thrombotic microangiopathy (59%), followed by CNS inflammatory diseases (14%) and hyperviscosity syndrome (7%). The majority of patients were treated by at least one immunosuppressive drug (89%). Overall, 32 patients had positive blood cultures, 9 were considered contaminated, leaving 23 BSI for analysis (9%). BSI occured after 4 (1-8) TPE procedures, double-lumen catheter being identified as the main origin for bloodstream infection (35%). Main identified germs were K. Pneumonia (26%), %), Staph. Aureus (16%), Ps. Aeruginosa (8%), M. Morganii (8%), E. Coli (8%). Comparing patients with and without BSI, we found higher BMI (25 (22-28) vs 28 (23-33), P=0.04), and more frequent catheter-related thrombosis in the infection group (5% vs 17%, P=0.06). No significant different was observed between groups regarding comorbidities, number of immunosuppressive drugs and central catheter position (femoral or jugular).","contentDiscussion":"","contentConclusion":"In ICU patients treated with TPE, BSI is not frequent and can be observed within the first week of treatment.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Pham HP, Staley EM, Schwartz J. Therapeutic plasma exchange - A brief review of indications, urgency, schedule, and technical aspects. Transfus Apher Sci. 2019 Jun;58(3):237–46.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Reeves HM, Winters JL. The mechanisms of action of plasma exchange. British Journal of Haematology. 2014;164(3):342–51.","presentateur":"FODIL Sofiane"},{"id":99465,"num":"A34461SM","reference":"FC-131","title":"Endotracheal bacterial kinetic changes from intubation to onset of pneumonia during mechanical ventilation: the core of VAP pathophysiology?","formatedAuthors":"Sylvain MEYER (1), Estelle DANCHE (1), Elie GUICHARD (2), Ana Catalina HERNANDEZ PADILLA (1), Anne-Laure FEDOU (1), Philippe VIGNON (1), Olivier BARRAUD (1), Bruno FRANÇOIS (1)
(1) CHU Dupuytren, Limoges, FRANCE ; (2) CHRU de Tours, Tours, FRANCE","contentIntroduction":"The presence of a tracheal tube for invasive mechanical ventilation (MV) may facilitate bacterial colonisation of the lower respiratory tract (LRT) but also will change patients’ respiratory microbiota, ultimately leading to the development of Ventilator-Associated Pneumonia (VAP) directly or through a Ventilator-Associated Tracheobronchitis step in some patients. Nevertheless, even if this concept is widely accepted, little is known regarding the exact bacterial kinetic changes in LRT secretions during MV. Although the first days of intubation seem critical for microbiological evolution, current knowledge of such colonisation process is limited, and descriptions are not conclusive due to important clinical heterogeneity among patient populations. The objective of the study was to exhaustively follow bacterial kinetic changes in all endotracheal secretions during the first seven days of MV starting right after intubation in a highly homogeneous and clean population.","contentPatientsMethods":"We conducted a prospective study in adult patients requiring MV for at least 7 days. In order to have a very “clean” population, patients had to be free from acute or chronic pulmonary disease, from any acute infectious disease and from antibiotic treatment for at least two weeks before inclusion. Patients were included from intubation and all endotracheal secretions collected as part of routine care by bedside nurses were collected around the clock until D7. MV patients were classified in VAP or no VAP group by an independent blinded adjudication committee, according to clinical, microbiological and radiological criteria.\n Quantitative microbiological culture was performed from each single endotracheal aspirate (ETA) following ESCMID recommendations. Common putative pathogens were identified with the Vitek MS (bioMérieux) and quantified.","contentResultats":"Forty-eight patients were included, 28 (58%) were men with a mean age of 58 (±15) years. Apache II score of 14.3 (±5.3), and Charlson Comorbidity Index of 2.8 (±1.9). Ten patients (21%) developed VAP. A total of 1556 ETA samples were collected (34 ETA on average per patient). Staphylococcus aureus and Haemophilus influenzae were the two most frequent pathogens identified in VAP and no VAP patients, 6 vs 20 patients and 8 vs 18 patients respectively. Mean number of common putative pathogens per patient was 2.6 (±1.3) and 3.6 (±1.7) in VAP and no VAP group respectively. Microbial colonisation showed no similar patterns or differences in terms of CFU evolution between both groups (Figure).","contentDiscussion":"","contentConclusion":"Bacterial quantification from ETA samples during intubation of patients with no confounding factors showed a high intra and intervariability that is not correlated to VAP onset","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MEYER Sylvain"},{"id":99466,"num":"A34493RP","reference":"FC-132","title":"Lung mycobiota ? diversity is linked to survival in critically ill patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease","formatedAuthors":"Pierre SIONIAC (1), Raphaël ENAUD (1), Sébastien IMBERT (1), Pierre-Laurent JANVIER (1), Hoang-Nam BUI (1), Odile PILLET (1), Arthur ORIEUX (1), Adrian CAMINO (2), Alexandre BOYER (1), Isabelle DUPIN (2), Patrick BERGER (2), Didier GRUSON (1), Laurence DELHAES (1), Renaud PRÉVEL (1)
(1) CHU Bordeaux, Bordeaux, FRANCE ; (2) Université Bordeaux, Bordeaux, FRANCE","contentIntroduction":"Chronic obstructive pulmonary disease (COPD) is a frequent disease affecting more than 200 million persons worldwide. The chronic course of COPD is frequently worsened by acute exacerbations (AECOPD). Mortality in patients hospitalized for hypercapnic AECOPD (the most severe) remains dramatically high and the mechanisms underlying those exacerbations are poorly understood. Lung microbiota has been demonstrated to be associated with COPD course and outcomes in non-hypercapnic AECOPD but no study specifically investigated hypercapnic AECOPD patients. The aim of this study is thus to compare lung microbiota composition between hypercapnic AECOPD survivors and non-survivors.","contentPatientsMethods":"Induced sputum or endotracheal aspirate was collected at admission of every consecutive hypercapnic AECOPD from October 2018 to March 2019. After DNA extraction, V3-V4 and ITS2 regions were amplified by PCR. Deep-sequencing was performed on MiSeq sequencer (Illumina®); data were analysed using DADA2 pipeline.","contentResultats":"Among 47 patients admitted for hypercapnic AECOPD, 25 (53%) with samples of sufficient quality were included, 21/25 (84%) of ICU survivors and 4/25 (16%) of ICU non-survivors.\n AECOPD non-survivors had lower lung mycobiota (p: 0.03, p: 0.05, p: 0.05), but not bacteriobiota (p: 0.71, p: 0.543, p: 0.70), α-diversity than survivors. Both lung bacteriobiota and mycobiota were not dissimilar between survivors and non-survivors (respectively, p: 0.91 and p: 0.88). Similar results were demonstrated comparing patients receiving invasive mechanical ventilation (n: 13 (52%)) with those receiving non-invasive ventilation (n:12 (48%). Previous systemic antimicrobial therapy and inhaled corticosteroids, but not systemic one, can alter the lung microbiota composition in hypercapnic AECOPD patients.","contentDiscussion":"","contentConclusion":"Non-survivors and patients requiring invasive mechanical ventilation have lower lung mycobiota, but not bacteriobiota, α diversity than survivors and patients only receiving non-invasive ventilation respectively. This study encourages for large multicentre cohort study investigating the role of lung microbiota in hypercapnic AECOPD and urges to investigate the role of fungal kingdom of lung microbiota in hypercapnic AECOPD pathophysiology.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ORIEUX Arthur"},{"id":99467,"num":"A34689JT","reference":"FC-133","title":"Citrulline enteral administration markedly reduces immunosuppressive plasma cell expansion in a preclinical model of sepsis","formatedAuthors":"Juliette GAUTHIER (2), Murielle GREGOIRE (2,3), Florian REIZINE (1,2,3), Mathieu LESOUHAITIER (1,2,3), Yoni DESVOIS (2), Karin TARTE (2,3), Jean-Marc TADIE (1,2,3), Céline DELALOY (2)
(1) Service des Maladies Infectieuses et Réanimation Médicale, Centre Hospitalier Universitaire de Rennes, Rennes, FRANCE ; (2) UMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang, LabexIGO, Rennes, FRANCE ; (3) Laboratoire Suivi Immunologique des Thérapeutiques Innovantes, Centre Hospitalier Universitaire de Rennes,, Rennes, FRANCE","contentIntroduction":"The mechanisms responsible for the sustained immunosuppression induced in sepsis that account for increased susceptibility to infection remain not entirely understood. Plasmablast and plasma cell subsets whose primary function is to secrete antibodies, have emerged as important suppressive populations expanded in infection and sepsis. The natural LAG3+ regulatory plasma cells can suppress immunity through IL-10 production, and sepsis supports CD39hi plasmablast metabolic reprogramming towards aerobic glycolysis responsible for their adenosine-mediated suppressive activity. Arginine deficiency described in sepsis has been linked to increased risk of recurrent infections. Overcoming arginine shortage by means of citrulline enteral administration was shown to efficiently improve sepsis-induced immunosuppression in the caecal ligation and puncture (CLP) model and secondary infection. Therefore, we tested here the hypothesis that citrulline administration may decrease plasmablast and plasma cell suppressive functions in sepsis.","contentPatientsMethods":"Splenic suppressive plasma cells have been characterized in a mouse model of sepsis. Animals underwent cecal ligation and puncture (CLP), received antibiotic therapy and fluid resuscitation. From day 0 to day 5, mice were enterally fed by citrulline (150mg/kg/day), arginine (150mg/kg/day) or an isonitrogenous placebo. Five days after surgery, immune dysfunctions following sepsis were studied.","contentResultats":"Citrulline administration markedly reduced the immunosuppressive LAG3+ plasma cells and the CD39hi plasmablast population expanded in CLP, a mechanism that could contribute significantly to the beneficial effect of citrulline.","contentDiscussion":"","contentConclusion":"Our study reveals sepsis induced-immunosuppressive plasma cells as highly responsive to nutrition and further supports the development of citrulline-based clinical studies to balance the immune system in sepsis.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1206","session":"FLASH COM - Infectieux","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction. Proc Natl Acad Sci U S A . 2022 Feb 22;119(8)","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TADIE Jean-Marc"},{"id":99468,"num":"A34607zH","reference":"FC-134","title":"Incidence and bacteriological profile of healthcare-associated infections (HAIs) in patients hospitalized for ARDS due to COVID-19","formatedAuthors":"Zeineb HAMMOUDA (1), Hédia BEN AHMED (1), Oussama SAADAOUI (1), Salma JERBI (1), Iyed MAATOUK (1), Manel LAHMAR (1), Fahmi DACHRAOUI (1), Fekri ABROUG (1), Lamia BESBES OUANES (1)
(1) CHU Fattouma Bourguiba MONASTIR, Monastir, TUNISIE","contentIntroduction":"Healthcare-associated infections (HAIs) are associated with an increase in morbidity and mortality in patients hospitalized in intensive care. The objective of this study is to determine the incidence of HAIs and to describe their bacteriological profile in the particular context of the COVID-19 pandemic.","contentPatientsMethods":"This is a retrospective study carried out between September 1, 2020 and September 30, 2021 in the intensive care unit of CHU FATTOUMA BOURGUIBA in MONASTIR, collecting the observations of patients admitted for ARDS due to COVID-19 whose stay was complicated by healthcare-associated infection. We analyzed the demographic, clinical and evolutionary characteristics as well as the results of the microbiological samples taken from these patients.","contentResultats":"440 patients were admitted to the ICU, 79 patients developed a HAI (18%). They were 45 men with an average age of 65 years. BMR screening was done in 53 patients and was positive in 17.7% of cases. The most frequent site of infection was the pulmonary site (52%) followed by hemato-vascular (9%) and urinary (2%) infection. The responsible micro-organisms are dominated by acinetobacter (24%) followed by pseudomonas aeruginosa (3.8%) and KP ESBL (3%). Of note, 17% of IAS were polymicrobial infections and in 30% of cases the micro-organism was not identified.\n The median length of stay was 15 days with a median prolongation of 5 days for the occurrence of an HAI. Curative antibiotic therapy was empirical in 62% of cases based on the combination tigecycline/colimycin (63%). The most common complication was septic shock which occurred in 81% associated with multi-visceral failure in 71% of cases. The mortality rate was at 84.8%.","contentDiscussion":"","contentConclusion":"In this study, the incidence of IAS was significant with a substantial impact on the outcome of patients with high mortality in case of infection.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HAMMOUDA Zeineb"},{"id":99469,"num":"A32092AT","reference":"FC-135","title":"Healthcare-Related Infections in Critical Patients with COVID-19: Epidemiology, Risk Factors and Outcomes","formatedAuthors":"Ahlem TRIFI (1), Lynda MASSEOUD (1), Amal MEFTEH (1), Selim SELLAOUTI (1), Cyrine ABDENNEBI (1), Sami ABDELLATIF (1), Salah BEN LAKHAL (1)
(1) Medical ICU, la Rabta hospital, Faculty of Medicine of Tunis, Tunis, TUNISIE","contentIntroduction":"The speed expansion of ICU beds and the redistribution of resources during the COVID-19 pandemic have made it difficult to comply with healthcare-related infection (HCRI) prevention measures. In Tunisia, one of the countries hardest affected by this pandemic, little or no data is available on the characteristics of HCRI in the COVID-19 era.\n Objectives: To study the epidemiology of HCRI in patients severely affected with COVID-19, to identify risk factors and to determine their prognostic impact.","contentPatientsMethods":"retrospective, observational and analytical study in critical patients with COVID-19. Microbiological samples were taken if HCRI was suspected. Factors influencing the occurrence of HCRI were: demographic criteria, co-morbidities, exposure to antibiotics and steroids, invasive procedures, clinical and paraclinical characteristics. Outcome parameters were sepsis/septic shock and mortality.","contentResultats":"157 patients were included, of which 60 (38.2%) presented at least one HCRI of mean age at 60+12 years, sex ratio=1.3 and of SOFA at 4+1.7. Hypertension (n=30) and diabetes (n=23) were the predominant defects. 117 HCRIs were recorded corresponding to an incidence density (ID) of 69.2 IN / 1000 HD and divided into VAP (n=38), bacteremia (n=32), urinary tract infection (UTI, n=24), catheter-related infection (CRI, n=12) and fungal infection (n=11). Compared to 2017, there was an increase of HCRIs, and the time to onset was earlier (attached figure). Acinetobacter baumannii (39.5%) and Klebsiella pneumoniae were the main isolated (27%) of which 89% had a profile sensitive only to colistin and 64.5% produced broad spectrum beta-lactamase respectively.\n Factors independently associated to HCRI were hyperglycemia (OR=12.8 [3.1-51]), elevated CRP (> 115 mg/l, OR=1.009 [1.001-1.017]), steroid use duration > 10 d (OR=1.25 [1.08-1.44]), arterial catheter (OR=6.57 [1.35-31]) and bladder catheterization (OR=43 [4-466]).\n Patients developing HCRI presented more septic origin (91% vs 72%, p<10-3). HCRI was an independent factor of mortality which multiplied it by 8 (OR=8.49, p=0.004). Other factors were also independently linked to mortality: mechanical ventilation (OR=23.5, p=10-3) and stage 3 ARDS (OR=7.22, p=0.007).","contentDiscussion":"","contentConclusion":"During the COVID period, the rate of HCRIs increased mainly VAP and UTI. Multi-resistant Acinetobacter B and Klebsiella P remained the most isolated pathogens. In addition to the common risk factors often reported even outside of COVID, hyperglycemia, elevated CRP, and prolonged corticosteroid duration were the original factors found associated with HCRIs in our cohort. When the HCRI grafted onto the evolutionary process of those critically ill with COVID, it amplified the risk of death by eight.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Trifi A, Abdellatif S, Oueslati M, Zribi M, Daly F, Nasri R, Mannai R, Fandri C, Ben Lakhal S. Nosocomial infections: current situation in a resuscitation-unit. Tunis Med. 2017 Mar;95(3):179-184. PMID: 29446811.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MASSEOUD Lynda"},{"id":99470,"num":"A34709IA","reference":"FC-136","title":"Prevalence and outcome of bacteremia among Covid 19 critically ill patients","formatedAuthors":"Ilef ALILA (1), Sana KHARRAT (1), Amina HADDED (1), Kamilia CHTARA (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) hopital Habib Bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"The COVID-19 epidemic has been a health threat worldwide causing multi-organ damage. This viral infection (COVID-19) is not the only cause of deaths in this pandemic. A usual complication of viral infections is a secondary bacterial infection or a superinfection (1).\n The aim of this study was to assess prevalence, characteristics and outcome of bacteremia in critically ill COVID-19 patients.","contentPatientsMethods":"We conducted a retrospective study in an ICU over a period of 16 months [September 2020-December 2021] including patients with SARS-COV2 infection.","contentResultats":"During the study period, 586 patients were included with a mean age of 59.5 ± 14.7 and a gender ratio of 1.6. The median SAPSII and SOFA score were respectively of 29 ± 14.8 and 4 ± 2.6. Most patients had comorbidities, including hypertension (36 %), obesity (32.1%) and diabetes (36.2%). Bacteremia was diagnosed in 42 (7.2%) patients after a mean hospital stay of 7.4± 4.5 day. The most frequently found germs were: Klebsiella pneumoniae in 10 (23.8%) patients, Enterococcus faecalis in 7 (16.7%) patients and Acinetobacter baumannii in 6 (14.3%). Those with bacteremia had significantly higher rates of septic shock (71.4% vs 41.2%; p< 0.001. Bacteremia was associated with longer length of stay. In addition, the use of invasive mechanical ventilation and mortality were significantly higher in bacteremia group (Table I).","contentDiscussion":"","contentConclusion":"Bacteremia is a severe complication in patients suffering from SARS-COV2 infection and requiring ICU admission. The development of Bacteremia is associated with poor outcome.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1)Nag V.L. · Kaur N: Superinfections in COVID-19 Patients: Role of Antimicrobials","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALILA Ilef"},{"id":99471,"num":"A34479pm","reference":"FC-137","title":"Impact of closed tracheal suction systems on bacterial respiratory samples in patients with SARS-CoV2 infection: a monocentric study.","formatedAuthors":"Pierre-Henri MURGAT (1), Anne CARRICAJO (1), Guillaume THIERY (1), Sophie PERINEL-RAGEY (1)
(1) CHU de Saint Etienne, Saint-Priest-En-Jarez, FRANCE","contentIntroduction":"During the COVID-19 pandemic, use of closed tracheal suction systems (CTSS) has become widespread in intensive care units (ICU) to reduce health care workers and environmental contaminations. These systems are frequently mobilized to aspirate the tracheo-bronchial secretions. Furthermore, they may be used to perform bacteriological samples by tracheal aspirations in case for example of suspected pneumonia. CTSS are set up for 3 days according to manufacturer and due to pandemic shortage conditions sometimes longer in several ICU. \n The aim of this study is to assess the influence of CTSS use on respiratory bacteriological samples.","contentPatientsMethods":"This prospective observational monocentric study realized in an ICU of University Hospital enrolled patients between April 2021 and February 2022 after ethical committee approval. Inclusion criteria were: active SARS-Cov-2 infection, CTSS use under invasive mechanical ventilation and need to change this system according to local practice recommendations. At time of CTSS replacement, we performed a microbiological analysis of the tracheal secretions before the removal. A second sample of tracheal secretions was taken through the new CTSS at first need of aspiration for the patient. Finally, a microbiological analysis was also carried out on the distal part of the CTSS removed.","contentResultats":"15 patients were enrolled, 3 were excluded for missing data. The mean duration of CTSS use was 6,3 days (±4.8) Of the 12 samples carried out on previous CTSS, 6 were sterile (50%). For these 6 patients, bacterial samples made through new CTSS were also sterile. CTSS culture was also sterile with the exception of two patients. The other 6 tracheal secretions made on previous CTSS have found bacteria classically implicated in ventilation acquired pneumonia (VAP) (1). There was no qualitative bacteriological difference between these 6 samples and the tracheal secretions made on the new CTSS. Cultures of the CTSS distal part found the same bacteria with one exception.","contentDiscussion":"We found a good agreement between bacteriological samples performed on previous CTSS and samples made through new CTSS. Consequently, no contamination of the device in place for several days was observed. This result is of importance as higher risk of VAP and of multi drug resistant bacteria was observed for SARS-CoV-2 ICU patients (1). Yet, these data do not inform on impact of CTSS for respiratory tract bacterial colonization and further studies are mandatory.","contentConclusion":"The study suggests that the realization of tracheal secretions through CTSS does not lead to bacterial contamination of the respiratory samples.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1)“Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease”, K Razazi and al; Crit Care. 2020 Dec 18;24(1):699. doi: 10.1186/s13054","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MURGAT Pierre-Henri"},{"id":99472,"num":"A34743JG","reference":"FC-138","title":"Healthcare-associated infections in critical COVID-19 forms","formatedAuthors":"Jihene GUISSOUMA (1,2), Hana BEN ALI (2), Insaf TRABELSI (1,2), Hend ALLOUCHE (1,2), Habib BRAHMI (1,2), Mohamed SAMET (2), Hatem GHADHOUNE (1,2)
(1) Faculté de médecine de Tunis, Bizerte, TUNISIE ; (2) Université Tunis El Manar, Tunis, TUNISIE","contentIntroduction":"Healthcare-associated infections (HCAI) have been well described in previous viral epidemics but reports about secondary infections associated to COVID-19 are limited. we aimed to discern the risk factors of HCAI in patients admitted to intensive care unit (ICU) for critical COVID-19 forms and their prognostic impact.","contentPatientsMethods":"A 16-month (september 2020-December 2021) prospective descriptive study including all patients admitted to ICU for critical COVID-19 forms. The patients were divided into two groups:\n -Group1: patients who developed HCAI during ICU stay.\n -Group2: patients who didn’t develop HCAI.\n \n The statistical analysis was performed using SPSS 23.","contentResultats":"Overall 140 patients were included. The mean age was 58±13 with male predominance. The most common comorbidities were hypertension (64%) and diabetes (62%). Four patients had auto immune disease history with immunosuppressor ongoing treatment.The mean IGS II and APACH II were 40±13 and 13±6 respectively. \n \n Fifty-nine bacterial HCAI were reported in 55 patients (group1 and group2 counted 55 and 85 patients respectively).\n Healthcare-associated pneumonia was the most common one (44 cases equal 74% of HCAI) followed by bacteremia (6 cases), urosepsis (3 cases), infection related to a central-line catheter (2 cases), infection of bedsores (2 cases) and colitis (2 cases). Only 24 among the 59 HCAI reported were documented. The most common microorganisms isolated were: Acinetobacter baumannii (8 cases), Pseudomonas aeruginosa (4 cases) and Stenotrophomonas maltophilia (2 cases).\n Besides, fungal infection was considered in 15 cases but only 7 were confirmed by cultures which isolates Candida albicans in 4 cases and non albicans in 3 cases. In the remaining cases, the diagnosis was based on candida score, clinical and biological criteria without a microbiological laboratory confirmation.\n The mean length of ICU stay was significantly higher (p<10-3) in group1 (17 days) compared to group2 (8 days).\n \n Overall mortality was 69%. It was higher in group 1 (85%) compared to group 2 (60%) with a statically significant difference (p=0,01).\n In univariate analysis, auto immune disease history (p=0,03), prior antibiotherapy (p=0,05), septic shock on admission (p<10-3) and invasive ventilation (p<10-3) were the main risk factors for acquiring HCAI. Only septic shock was an independent risk factor in multivariate analysis (p=0,05).","contentDiscussion":"","contentConclusion":"the occurrence of HCAI in critical COVID-19 forms was frequent in our study. It was associated to a poorer outcome and a longer ICU stay. Septic shock on admission was the only independent risk factor for acquiring HCAI. These results need to be confirmed by further larger studies.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHADHOUNE Hatem"},{"id":99473,"num":"A34701MG","reference":"FC-139","title":"The Impact of hospital-acquired infections on critically ill COVID-19 patients’ outcome","formatedAuthors":"Mohamed Khalil GHOZZI (1), Amira JAMOUSSI (1), Ines SDIRI (1), Samia AYED (1), Emna RACHDI (1), Fatma JARRAYA (1), Mohamed BESBES (1), Jalila BEN KHELIL (1)
(1) Hôpital Abderrahmen Mami , Ariana, TUNISIE","contentIntroduction":"Hospital-acquired infections (HAI) have been constantly reported in critically ill patients with COVID-19. The aim of the present study was to assess characteristics and outcome of critically ill COVID-19 patients whom ICU stay was complicated with HAI.","contentPatientsMethods":"We conducted a retrospective single-center, case-control study including patients with COVID-19 infection admitted to the ICU between March 2020 and September 2021. We evaluated clinical features and outcome of critically ill COVID-19 patients with HAI.","contentResultats":"During the study period, 544 patients were collected. The mean age was 59 ± 13 years [18-95] with a gender-ratio (H/F) of 1.66. The mean SAPS II and APACHEII scores were 28 ± 10 and 10.3 ± 5, respectively. Invasive mechanical ventilation was required in 57.2% of patients. Two hundred thirty-seven (43.5%) patients developed a HAI. The most common HAI was pneumoniae (28.3%), followed by urinary tract infection (13.2%), bacteremia (11%) and central line-associated bloodstream infection (4.6%). Comparison of clinical and outcome findings between HAI and non-HAI patients is reported in table 1.","contentDiscussion":"","contentConclusion":"HAIs are frequent among critically ill COVID-19 patients. They substantially worsen patients’ outcome and significantly extend ICU length of stay. As it has always been in ICU, HAIs management and prevention represents a serious challenge to healthcare professionals globally during the COVID-19 pandemic.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHOZZI Mohamed Khalil"},{"id":99474,"num":"A34741ER","reference":"FC-140","title":"Nosocomial infection profile in critically-ill covid-19 patients","formatedAuthors":"Ines SDIRI (1,2), Emna RACHDI (1,2), Mohamed Khalil GHOZZI (1,2), Amira JAMOUSSI (1,2), Fatma JARRAYA (1,2), Mohamed BESBES (1,2), Samia AYED (1,2), Jalila BEN KHELIL (1,2)
(1) Hopital Abderrahman Mami, Ariana, TUNISIE ; (2) Faculté de médecine de Tunis, Tunis, TUNISIE","contentIntroduction":"Nosocomial bacterial and fungal infections (NI) have been reported in patients with COVID-19, resulting from an immunosuppressed state. However, few data are available on these infections in critically ill patients.\n The objective of this study was to evaluate the characteristics of ICU-acquired infections in COVID-19 patients and to establish the microbiological profile","contentPatientsMethods":"It was a retrospective descriptive study including adults with COVID-19 admitted in ICU of Abderahmen Memi Hospital, from March 2020 to December 2021. Demographic, clinical, microbiological and therapeutic data were collected. We evaluated the epidemiological and microbiological features of NI.","contentResultats":"During the study period, 544 patients were collected. The median age was 59 years [18-95] with a gender ratio of 1.66. Mean SAPS II and APACHEII scores were 27.9 ± 10 and 10.3 ± 5, respectively. The most common histories were hypertension (39%) and diabetes (36.6%) with a mean BMI of 30.79 kg/m2. All patients received dexamethasone and 44% had antibiotic therapy on admission. Four hundred fifty-one patient (82.9%) required noninvasive ventilation and 311 (57.2%) needed invasive ventilation with a median delay of 3 days [0-24d] from admission. NI complicated 237 patients (43.5%) with a total of 333 episodes (90 patient had 1 episode, 33 had 2, 20 had 3 and 23 had more then3 episodes), 9% of them were acquired in other departments and discovered at admission. Pneumopathy acquired under mechanical ventilation was the major NI and represented 81%. Bacteria isolated in these cases were non-fermenting germs (65%) (Pseudomonas aeruginosa and Acinetobacter baumannii imipenem resistant) and Enterobacteriaceae (47%), in particular Klebsiella pneumoniae BLSE. Urinary infection (13.2% of IN) was dominated by enterocoques in 27 cases (among them 2 cases of ERV), Escherichia Coli in 12 and Klebsiella Pneumoniae in 4 (1 was BLSE). Bacteremia and catheter-related bloodstream were observed in 11% and 4.6% of cases respectively. Four per cent of NI was fungal infection and the most identified germ was Candida Albicans. NI was associated with septic shock in 74.5% of cases. Mortality rate was 54.8% due to septic shock with multiple organ failure in 33% of cases.","contentDiscussion":"","contentConclusion":"Bacterial and fungal nosocomial infection is a common complication seen in ICU patients, more observed and repeated in COVID-19 patients. It is often a severe form of infection, dominated by Gram-negative resistant bacteria acquired during ICU stay and associated with a poor prognosis.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1207","session":"FLASH COM - COVID-19 et infections acquises","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SDIRI Ines"},{"id":99475,"num":"A34246CG","reference":"FC-141","title":"Delivery of high flow oxygen through nasal versus tracheal canula. A bench study","formatedAuthors":"Claude GUÉRIN (1,2), Martin COUR (1), Florian DEGIVRY (1), Laurent ARGAUD (1), Bruno LOUI (2)
(1) Hôpital Edouard Herriot Hospices Civils de Lyon, Lyon, France, FRANCE ; (2) Institut Mondor de Recherches Biomédicales, Créteil, FRANCE","contentIntroduction":"High flow oxygen therapy (HFOT) has increasingly been used in the Intensive Care Units, in particular during the SARS-Cov2 pandemic. Furthermore, the kind of devices to perform HFOT has also increased with dedicated devices and ICU ventilators equipped with this function. Finally, HFOT can be delivered through nasal or tracheal canula. This bench study was motivated by the comparison of the work of breathing (WOB) across HFOT devices and canula.","contentPatientsMethods":"Seven devices were tested: the original device (Optiflow), two HFOT dedicated devices (Airvo2 and HM80) and 4 ICU ventilators offering this function (G5, T60, V500 and V60). Each device was connected to a lung model (ASL 5000) set with compliance 40 ml/cmH2O, resistance 10 cmH2O/L/s at a simulated inspiratory effort of -10 cmH2O delivered at 30 breaths/min. Nasal (Optiflow 3S medium size, Fisher and Paykel) and tracheal (OPT 970, Fisher and Paykel) canula were attached to a specific manikin head and connected to the HFOT device on one hand and to the lung model on the other hand. Each device was tested in each canula at a 40 L/min oxygen flow delivered at ambient temperature (heated humidifier set in the circuit but off) and FIO2 0.21 for two minutes. The data were recorded with ASL software and analyzed via an application developed in the Matlab environment. On each breath the WOB was measured by using the Campbell diagram, then multiplied by the respiratory rate and expressed as J/min. The effects of canula and device were tested by two-factor ANOVA. The values are expressed in median (1-3 quartiles) for the reference device (Optiflow) and in relative variation from it for each device.","contentResultats":"With the Optiflow reference device the WOB was 3.7 (3.7-3.8) and 3.46 (3.5-3.5) J/min with the nasal and the tracheal canula, respectively (P<0.05). With the nasal canula the relative variations from the reference device were 4.6, 6.2, 2.4, 4.5, and 2.2 % for Airvo2, G5, HM80, T60, V500 and V60, respectively (P<0.05 vs the reference for each device). For the tracheal canula the corresponding values of the devices were 1.2, 1.5, 2.6, 0.6, 1.2 and 2.6 %, respectively (P<0.05 for each device). The relative variations were significantly different between nasal and tracheal canula as was the interaction between canula and devices.","contentDiscussion":"","contentConclusion":"The WOB was lower with tracheal than with nasal canula for every device. The differences between devices may not be clinically relevant.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GUÉRIN Claude"},{"id":99476,"num":"A34472FL","reference":"FC-142","title":"Evaluation of the new heated wire humidifier FP950 under varying ambient temperature conditions","formatedAuthors":"Pierre-Alexandre BOUCHARD (1), Emilie ROUSSEAU (1), Francois LELLOUCHE (1)
(1) Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec City, CANADA","contentIntroduction":"It has been previously shown that heated wire humidifiers performances were influenced by ambient air temperature. When ambient temperature is high, heater plate temperature decreases to maintain chamber temperature stable at 37°C. Consequently, the humidification performances are significantly reduced, well below 30 mgH2O/L of absolute humidity with risk of endo-tracheal tube occlusion. These performances are partially improved with specific settings (increased chamber temperature to 40°C or activation of compensation algorithm)(1). The aim of the study was to evaluate the new generation heated wire humidifier FP950 that adds parameters in its algorithm (including ambient temperature) to maintain a stable humidity delivered to patients.","contentPatientsMethods":"We measured on bench the hygrometry of inspiratory gases delivered by (i) FP950 (Fisher&Paykel Healthcare, Auckland, New Zealand) (ii) MR850 with usual settings (37 at the chamber/40 at the Ypiece) (iii) MR 850 with no temperature gradient (40/40), and (iv) MR850 with compensation algorithm activated. Hygrometry was measured with the psychrometric method(1) after at least one hour of stability while varying the room temperature from 20 to 30°C.\n In another set of experiments, we continuously measured ambient temperature in several ICU rooms (with different exposure), at our institution with (EL (EasyLog) -USB-1 temperature data logger, Lascar Electronics) during several months. One measure every 30 minutes is recorded by this device.","contentResultats":"We performed 178 hygrometric measurements at steady state for the different conditions tested. The main results are shown in the figure. With the new heated wire heated humidifier MR950, the mean humidity delivered remained stable at 35.4±1.3 mgH2O/L of delivered absolute humidity, despite variations of the ambient temperature from 19.9 to 30.3°C. Minimim values of absolute humidity were 31.1 mgH2O/L with FP950, 19.8, 26.6 and 25.5 with MR850 set at 37/40, 40/40 and with activated compensation respectively.\n With ambient temperature above 27.5°C, absolute humidity was 34.2 mgH2O/L, compared to 23.1 mgH2O/L with MR850 (37/40), P<0.001, 31.6 mgH2O/L with MR850 (40/40), p=0.004, and 29.3 mgH2O/L with MR850 and compensation algorithm activated (P<0.001).\n The continuous measurement of the ambient temperature in ICU rooms showed that the temperature tested in the bench study were relevant to the clinical practice in Quebec city with temperatures varying from 20 to 29°C.","contentDiscussion":"","contentConclusion":"The new heated wire heated humidifier FP950 demonstrated stable performances while varying ambient temperature from 20 to 30°C. The humidification performances were better than did previous generation of heated humidifier when ambient temperatures were high.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Lellouche L, Taillé S, Maggiore SM, Qader S, L'Her E, Deye N, et al. Influence of ambient air and ventilator output temperature on performances of heated-wire humidifiers. Am J Respir Crit Care Med 2004;170:1073-1079.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LELLOUCHE Francois"},{"id":99477,"num":"A34549FL","reference":"FC-143","title":"Monitoring of heated wire humidifier hygrometric performances with heater plate temperature","formatedAuthors":"Francois LELLOUCHE (1), Serge SIMARD (1), Pierre-Alexandre BOUCHARD (1)
(1) Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec City, CANADA","contentIntroduction":"Under-humidification and associated complications may occur with heated humidifiers. Endo-tracheal tube occlusions and subocclusions have been shown even with these devices. Hygrometric performances of heated wire humidifiers are reduced by high ambient and high outlet ventilator temperatures. Currently, there is no reliable monitoring tool to evaluate humidification performances of heated wire humidifiers in the daily practice.\n The objectives of this study were to demonstrate the relation between humidity delivered by heated wire humidifiers and different parameters that could be used to monitor humidity of gas delivered to patients.","contentPatientsMethods":"On a bench test, we measured heater plate temperature, inlet chamber temperature and delivered humidity with MR850 system (Fisher & Paykel). Temperature displayed on the humidifier was also recorded. The measurements were performed at different ambient temperatures and 5 minute ventilation levels (5, 7.5, 10, 12.5, 15 l/min) set on a ICU ventilator. Inlet chamber temperatures varied from 20 to 40°C. In each condition, hygrometric measurements with the psychrometric method were performed at steady state.\n We evaluated the relationship between heater plate temperature and humidity delivered and the factors that may alter this relationship.","contentResultats":"We performed 279 hygrometric measurements at steady state including all conditions and concommittant heater plate, ambient, chamber temperature were recorded. We found a good correlation between heater plate temperature and absolute humidity delivered (R2 = 0.82). This relationship was hardly affected by ambient temperature, but minute ventilation had more effect (Figure). For different minute ventilations, the correlation between heater plate temperature and absolute humidity delivered were very good with coefficient of determination R2 from 0.87 to 0.98 (Figure). Heater plate temperature above 62°C was a very good predictor of absolute humidity delivered above 30 mgH2O/L (AUC = 0.96, sensibility 79%, specificity 94%). No correlation existed between humidity delivered and the outlet chamber temperature (displayed on the humidifier).","contentDiscussion":"","contentConclusion":"In this bench study, we have shown a good correlation between heater plate temperature and humidity delivered with a heated wire humidifier. This parameter could be used as a surrogate of humidity to improve the humidification monitoring.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LELLOUCHE Francois"},{"id":99478,"num":"A34572FL","reference":"FC-144","title":"Hygrometric performances of Heat and Moister Exchangers with low dead space","formatedAuthors":"Pierre-Alexandre BOUCHARD (1), Emilie ROUSSEAU (1), Richard BRANSON (2), Francois LELLOUCHE (1)
(1) Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec City, CANADA ; (2) Department of Surgery, Division of Trauma & Critical Care, University Cincinnati , Cincinnati , ETATS-UNIS","contentIntroduction":"Providing gas humidification greater than 28 mgH2O/L is mandatory for patients with prolonged intubation, with either heat and moisture exchangers (HME) or heated humidifiers (HH). In patients requiring lung protective ventilation, HH is the first line humidification device to minimize dead space. When transporting these patients, it is important to use HMEs with low dead space and sufficient humidity delivered. In this study, we have evaluated hygrometric performances of 7 devices (4 HMEs and 3 filters) with low deadspace.","contentPatientsMethods":"We tested on a bench, the hygrometric performances of four HMEs: BACT HME 6310 (47 ml), Pharma system - DYNJAAHME10 (36 ml), Medline - HUMID VENT 2S (28 ml), Teleflex Medical - DAR HME small (51 ml), Medtronic and three Filters: HEPASHIELD (47 ml), Flexicare - AQUASURE (32 ml), Bomimed - DAR filter (36 ml), Medtronic. We have used psychrometric method to measure hygrometry at steady state, with expiratory humidity of 35 mgH2O/L simulated as previously described. For each condition, 3 hygrometric measurements were performed with similar conditions for ambient air temperature 25±0.5°C, and ventilator settings (respiratory rate 20/min, tidal volume 500 ml, FiO2 21 %, PEEP 5 cmH2O, square flow 60l/min).\n We compared data obtained on bench with data provided by manufacturers.","contentResultats":"We performed 3 hygrometric measures for each tested device and compared to the data provided by the manufacturers.\n Large differences were shown between HME (from 29.2 to 25.4 mgH2O/L) and Filters (18.2 to 10.4 mgH2O/L). Large differences existed between humidity measured by the psychrometric method (our bench) and the data provided by the manufacturers (available for 6 devices). \n The main results are presented on the figure.","contentDiscussion":"","contentConclusion":"Several HMEs with small dead space provide sufficient gas humidity and may be used during transport for patients with lung protective ventilation. However, important differences were found in terms of humidification performances for small dead space HMEs and filters. For prolonged utilization, humidity delivered should be above 28 mgH2O/L. For short-term utilization (few hours), it may be acceptable to use HMEs with humidity delivered above 25 mgH2O/L, but filters without sufficient humidity must not be used. Data provided by manufacturers obtained with gravimetric method may not be reliable.","published_at":"2022-06-16T16:01:24.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:24.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LELLOUCHE Francois"},{"id":99479,"num":"A34595ME","reference":"FC-145","title":"Aerosoltherapy and Mechanical Ventilation: Effect of the position and orientation of an inhalation chamber into an adult ventilation circuit on in vitro drug delivery.","formatedAuthors":"Myriam ECKES (1), Brenda HERVIEU (1), Quentin BEQUET (1), Thierry PORÉE (1)
(1) Laboratoire optimHal, Valognes, FRANCE","contentIntroduction":"Positioning the pressurized metered dose inhaler (pMDI) device on the inspiratory branch of a mechanical ventilation circuit is safer especially with a high internal volume spacer. Indeed the volume of the device is added to the dead space. However, inserting the devices between the Y piece and the endotracheal tube could be convenient especially when using tubing bonded with Y piece. Tubing dimensions are not the same depending on the position of the device on the circuit. inhaler devices conceived to be inserted into the inspiratory branch of an adult MV circuit can only be used oriented at the opposite as indicated in instructions for use (IFU) when devices are inserted between the Y piece and the endotracheal tube (ETT). Otherwise, adapters are needed. This study aimed to evaluate the effect of position of two different inhaler devices and orientation of pMDI nozzle on drug delivery.","contentPatientsMethods":"A ventilator was used in volume-controlled mode with adult respiratory parameters. The inhaler devices, CombiHaler® (Laboratoire OptimHal) and a T adapter (Intersurgical) were inserted into two different positions: 1) in the inspiratory limb with the pMDI nozzle oriented to the patient and 2) between the ETT and the Y piece with the orientation reversed. Ten doses containing 100 µg of salbutamol were actuated in the prototypes during inspiration. The delivered dose was collected on a filter inserted between the ETT and the test Lung.","contentResultats":"Results showed an equivalent drug delivery when CombiHaler® is inserted in the inspiratory branch and between the ETT and the Y piece with orientation reversed. The drug dose delivered is higher when using the T adapter in the inspiratory branch in comparison with after the Y piece with the orientation reversed. The results could be explained by the high volume of the spacer which could keep the drug particles into the spacer and avoid impaction into the Y piece and tubings.","contentDiscussion":"","contentConclusion":"Using the spacer in the reverse orientation doesn’t seem to affect drug delivery while orientation of the aerosol spray with the T adapter has an impact on drug delivery.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ECKES Myriam"},{"id":99480,"num":"A34586jb","reference":"FC-146","title":"Comparison of aerosol deposition in the respiratory tract under spontaneous and non-invasive ventilation","formatedAuthors":"Jordan BONSIGNORE (1), Leclerc LARA (2), Jérémie POURCHEZ (2), Nathalie PREVOT (1), Sophie PERINEL-RAGEY (1)
(1) CHU SAINT-ETIENNE, Saint-Priest-En-Jarez, FRANCE ; (2) MINES SAINT-ETIENNE, Saint-Etienne, FRANCE","contentIntroduction":"Nebulization is a common route of administration for medications in ICU. For example, aerosols are fundamentals in association with non-invasive ventilation (NIV) for an exacerbations of chronic obstructive pulmonary disease (COPD). Nevertheless, nebulization practices are numerous, frequently led only by data from in vitro studies. To improve our practices, the AIM of this study is to evaluate the aerosol deposition when aerosols are realized during NIV or spontaneous breathing in an ex vivo preclinical model.","contentPatientsMethods":"The ex vivo respiratory model, was previously validated(1), composed of a porcine respiratory tract (RT), placed in a sealed enclosure. Spontaneous breathing was performed through a head replica with facial mask or a NIV mask according to the condition. During NIV we used a medical ventilator set in spontaneous breathing with pressure support; for the face mask an additional gas flow of 1L/min or 6L/min was used according to manufacturer recommendations. The vibrating mesh nebulizer was filed with 99mtechnetium-labeled diethylene-triamine-penta-acetic acid. We performed a gamma camera acquisition to quantify the deposited fractions in each part of the setting","contentResultats":"The model was setup 3 times for each condition. The mean deposited fractions in each component lead to the figure 1. For NIV conditions, (PART A), they reached respectively (results express in % of nominal dose): 17% (± 6%) in RT, 3% (± 2%) in face mask, 26% (± 8%) in head replica, 14% (± 1%) in inspiratory limb and 22% (± 2%) in expiratory limb and pump filter with 18% (± 2%) of leaks. For face mask conditions with gas flow of 1L/min then 6L/min (PART B), they reached: 36% (± 8%) and 25% (± 3%) in RT, 36% (± 8%) and 20% (± 1%) in face mask, 21% (± 3%) and 21% (± 2%) in head replica with 5% (± 2%) and 21%(± 0%) leaks.","contentDiscussion":"With vibrating mesh nebulizer, aerosols performed with face mask and smallest gas flow increased the deposited fractions in RT from 17% under NIV to 25% at 6L/min 36% at 1L/min. These results are in accordance with França et al (2) who showed a deposited fraction reduced of 50% in healthy volunteers when performing aerosols during NIV.","contentConclusion":"The ventilation mode and interface impact the aerosol deposition, other conditions being reproductive. The optimal condition using a facemask with gas flow of 1L/min must be taken in consideration by clinician to optimize nebulization practices when it is safe for patients.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Montigaud Y, Georges Q, Pourchez J, Leclerc L, Goy C, Clotagatide A, et al. Aerosol delivery during invasive mechanical ventilation: development of a preclinical ex vivo respiratory model for aerosol regional deposition. Sci Rep. 29 nov 2019;9(1):17930.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"França EET, Andrade AFD de, Cabral G, Filho PA, Silva KC, Filho VCG, et al. Nebulization associated with Bi-level noninvasive ventilation: Analysis of pulmonary radioaerosol deposition. Respir Med. 1 avr 2006;100(4):721?8.","presentateur":"BONSIGNORE Jordan"},{"id":99481,"num":"A34582AD","reference":"FC-147","title":"Clinical impact of the oximeters’ inaccuracy (bias and errors) – secondary analysis of the oxygap study","formatedAuthors":"Antoine DELOBEL (1), Marie-Anne BLANCHET (1), Gabriel MERCIER (1), Émi NAYET (1), Pierre-Alexandre BOUCHARD (1), Serge SIMARD (1), Erwan L'HER (2), Richard BRANSON (3), François LELLOUCHE (1)
(1) Centre de recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec (Qc), CANADA ; (2) Medical Intensive Care Unit, CHRU Brest – La Cavale Blanche, Brest, FRANCE ; (3) Department of Surgery, Division of Trauma & Critical Care, University Cincinnati, Cincinnati, ETATS-UNIS","contentIntroduction":"Pulse oximetry is daily used worldwide to measure SpO2 in order to monitor and titrate oxygen support. We previously showed that four among the most frequently used oximeters have significant bias (systematic errors from -3% to +1%) and inaccuracy (random error) in comparison with the gold standard SaO2. The main objective of this study was to highlight the impact of the oximeters’ variability on monitoring and clinical decisions in acutely ill patients.","contentPatientsMethods":"We prospectively included 210 stable ICU patients with an arterial catheter in place. For all included patients, we compared SpO2 values for each of the four evaluated oximeters (Nonin, Nellcor, Massimo and Philips) and concomitant PaO2 and SaO2 values from the arterial blood gases. When the patients met the criteria for hypoxemia (SaO2 < 90% or PaO2 < 60 mmHg), we evaluated which oximeter could detect hypoxemia (SpO2 < 90%). For each measurement, we evaluated for each oximeter when the oxygen support should be maintained even, increased or decreased to maintain a SpO2 value between 92 and 96%.","contentResultats":"Mean age of the patients was 66.3 year, 73% were men, skin pigmentation was light (Fitzpatrick 1 or 2 in 96.2% of the patients). The SpO2-SaO2 bias went from -3.1% (Nonin), to +0.9% (Philips) (P<0.001). With Nellcor and Masimo, bias were -0.3 (P<0.03) and -0.2% (P=0.17) respectively. Nonin oximeter underestimated arterial oxygenation in 91% of the cases but detected 100% of hypoxemia defined by PaO2<60 mmHg. Philips overestimated oxygenation in 55% of the cases but detected 11% of episodes of hypoxemia. Based on the oximeter used, the management of oxygen support to maintain the patients within a SpO2 target of 92-96% differed a lot. To keep the patients within this SpO2 target, in the cohort of 210 patients, it would be required to increase oxygen in 60.6% vs. 19.1% vs. 18.7% vs. 10.4% and to decrease oxygen in 1.0% vs. 6.2% vs. 9.1% vs. 20.9% of the cases (p<0.0001) when using Nonin, Nellcor, Masimo or Philips oximeter respectively (see Figure).","contentDiscussion":"","contentConclusion":"The variability of SpO2 measurements between oximeters has a significant impact on the monitoring and management of oxygen support. The bias of each oximeter should be known by clinicians and SpO2 targets should be adapted to the oximeter brand used by clinicians.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DELOBEL Antoine"},{"id":99482,"num":"A34752GM","reference":"FC-148","title":"Accuracy and reliability of low-cost versus high-cost oximeters – A secondary analysis of the OXYGAP study","formatedAuthors":"Gabriel MERCIER (1), Marie-Anne BLANCHET (1), Antoine DELOBEL (1), Emi NAYET (1), Pierre-Alexandre BOUCHARD (1), François LELLOUCHE (1)
(1) Institut de cardiologie et de pneumologie de Québec, Québec, CANADA","contentIntroduction":"Pulse oximetry is a technology used regularly to monitor oxygen saturation and titrate oxygen needs. However, these machines are expensive, limiting access in universal health care especially in low-income countries. In recent years, low-cost oximeters have become more available, but there is little validation on their effectiveness. In the main study, we examined the bias between different high-cost and two low-cost oximeters. The main goal of this study was to compare the accuracy and reliability between some low-cost and high-cost oximeters to determine if low-cost oximeters can be adequate options in chosen situations.","contentPatientsMethods":"This prospective study included 210 stable ICU patients with arterial catheter. Six oximeters were evaluated including four high-cost (Nonin (Plymouth, MN), Massimo (Irvine, CA), Philips (Eindhoven, Netherlands) and Nellcor (Pleasanton, CA)), as well as two low-cost oximeters (Contec CMS50DL and Beijing Choice C20). The low-cost ones were chosen based on a previous study on accuracy of low-cost oximeters were only the Contec CMS50DL and Beijing Choice C20 met the International Organization for Standardization (ISO) criteria for accuracy. Comparisons between pulse oximeter readings (SpO2) and arterial saturation (SaO2) were used to calculate bias (SpO2-SaO2). Reliability of each oximeter was evaluated by the percentage of times the oximeter could give a reading.","contentResultats":"Mean arterial saturation was 93.6%. High-cost oximeters had a mean bias between -3.1% with Nonin and 0.9% with Philips. In comparation, low-cost oximeters had a bias of -2.9% for Contec CMS50DL and -0.8% for Beijing Choice C20. While the majority of high-cost oximeter (Nellcor, Massimo, Philips) had a bias less than ±1.0%, only Beijing Choice C20 had similar result. However, low-cost oximeters were less reliable than high-cost ones with Beijing Choice C20 giving readings 92.9% of the times vs high-cost oximeters giving readings >97% of the times (See figure).","contentDiscussion":"","contentConclusion":"We found that some low-cost oximeters can have a similar accuracy with high-cost oximeters in some clinical settings. These low-cost oximeters could help giving more access to universal health care, especially in low-income countries.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1208","session":"FLASH COM - Aérosol, humidification et monitoring","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Lipnick MS, Feiner JR, Au P, Bernstein M, Bickler PE. The Accuracy of 6 Inexpensive Pulse Oximeters Not Cleared by the Food and Drug Administration: The Possible Global Public Health Implications. Anesth Analg. 2016 Aug;123(2):338-45. doi: 10.1213/ANE.000","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MERCIER Gabriel"},{"id":99483,"num":"A34543RT","reference":"FC-149","title":"Invasive mechanical ventilation management and trends in COVID-19-related acute respiratory distress syndrome","formatedAuthors":"Radhouane TOUMI (1,2), Khaoula MEDDEB (1,2), Nabil BOUGUEZZI (1), Hajer ZOUARI (1), Nermine BOUABDALLAH (1), Rim EL KACEH (1), Imen BEN SAIDA (1,2), Mohamed BOUSSARSAR (1,2)
(1) Medical Intensive Care Unit, Farhat Hached University Hospital, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, University of Sousse, Sousse, TUNISIE","contentIntroduction":"COVID-19-related acute respiratory distress syndrome (CARDS) requiring invasive mechanical ventilation (IMV) is generally associated to a prolonged length of IMV and to a poor prognosis. Adapting IMV management according to patients’ elastic properties is mandatory to help reduce mortality. The aim of the study is to describe IMV management as in ventilator settings and parameters and trends in the management of CARDS requiring IMV.","contentPatientsMethods":"This is a descriptive retrospective study carried out in a 12-bed medical intensive care unit (MICU) of a University Hospital from March 2020 to September 2021. All patients admitted for a critical CARDS requiring IMV were included. Data on patients’ characteristics at ICU admission, clinical presentation, ARDS and COVID-19 severity, ventilatory management, ventilatory settings, airways pressures, compliance, oxygenation index[(Plateau*FiO2*100)/PaO2)], ventilatory ratio[[VR=(Minute ventilation*PaCO2)/(Predicted body weight*100*37.5)]] and outcomes were collected. Evaluation was carried out at H1 post-intubation, day5 and day10, at a fixed time. This is the second paper of the database served to inquire about several aspects of CARDS.","contentResultats":"During the study period, a total of 214 patients underwent IMV for CARDS; 200(93.5%), severe to critical COVID-19. They were median aged 67.5[59.75-73] yrs; male, 146(68.2%); Hypertension, 106(49.5%); diabetes, 104(48.6%) and obesity, 89(41.6%). Moderate ARDS, 69(32.2%); severe ARDS, 141(65.9%); median P/F ratio at admission, 95[77-132]; moderate to severe acute respiratory failure 185(86.4%); median SAPSS II, 33[27-38]. Chest-CT scan was performed in 114(53.3%) patients showing 68(59.6%) with at least 50% of lesion extension. Table1 displays trends in ventilator settings and physiological parameters at H1, day 5 and day 10. Overall mortality rate was 180(84.1%).","contentDiscussion":"","contentConclusion":"Albeit poor outcome in mechanically ventilated CARDS patients, management was mostly in line with ARDS guidelines, however, trends seem to show progressive worsening of patient elastic properties.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUGUEZZI Nabil"},{"id":99484,"num":"A34734AK","reference":"FC-150","title":"Hospital morbidity of COVID-19 patients: hospitalized patients from December 2021 to date","formatedAuthors":"Ahmed KADI (1), Fella MEGDOUD (1), Abdelhak BOUGHERARA (1), Noureddine ZIDOUNI (1), Merzak GHARNAOUT (1)
(1) CHU BENIMESSOUS ALGER ALGERIE , Alger , ALGERIE","contentIntroduction":"identify the characteristics of hospitalized patients and bring out the seriousness factors concerning COVID-19","contentPatientsMethods":"This observational, descriptive and retrospective study concerned 100 cases of SARS/COV2 infections from December 2021 to the present day, hospitalized in the pneumo-phtisiology department","contentResultats":"The average age of the cases admitted to the study was 62 years with a male predominance (60%), the 2 most frequent comorbidities were respectively hypertension (44%) and diabetes (18%). Unvaccinated patients were 60% of cases, no patient had a history of COVID-19 disease. Family exposure represented 55% of cases, while occupational exposure was found in only 11% of cases. The involvement on chest CT was estimated at less than 10% in 3% of cases, between 10 and 25% in 15% of cases, between 25 and 50% in 40% of cases, between 50 and 75% in 28% of cases, and above 75% in 9% of cases. Lymphopenia was present in 93% of patients, CRP was elevated in 97% of patients. D. dimers were elevated in 52% of patients. Renal involvement was observed in 22% of patients. Cytolysis was present in 19% of hospitalized patients. Deaths accounted for 18% of hospitalized patients, half of whom were vaccinated.","contentDiscussion":"","contentConclusion":"Viral infection by the coronavirus is a new pathology with clinical manifestations of varying severity, digestive manifestations were more frequent in the series studied. Familial exposure was frequent. Inflammatory syndrome is common causing lesional pulmonary edema in some patients.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Wu Y, Ho W, Huang Y, Jin D-Y, Li S, Liu S-L, et al. SARS-CoV-2 is an appropriatename for the new coronavirus. Lancet 2020; 395 (10,228): 949–50.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382 (8):727–33.","presentateur":"KADI Ahmed"},{"id":99485,"num":"A34691FJ","reference":"FC-151","title":"COVID-19 and Underlying lung disease: What is known about risk and care management?","formatedAuthors":"Racha GHABARA (1), Fatma JARRAYA (1), Emna RACHDI (1), Amira JAMOUSSI (1), Samia AYED (1), Jalila BEN KHELIL (1)
(1) hôpital Abderrahmane mami, Ariana, TUNISIE","contentIntroduction":"Patients with COVID-19 who have underlying chronic lung disease (ULD) are at increased risk for developing a severe illness related to the disease. However, to date, few studies have been published about patients with ULD.\n The aim of this study was to evaluate the impact of ULD on clinical characteristics, adverse outcomes, and mortality in patients with critical COVID-19.","contentPatientsMethods":"It was a retrospective comparative cohort study including all patients hospitalized in ICU for COVID-19 between March 2020 and Sept 2021. Two groups were studied according to the presence or not of ULD. Primary outcomes were the use of mechanical ventilation (MV), ICU length of stay (LOS), and death.","contentResultats":"We included 148 patients of which 102 were males (ULD group, n=74 versus no ULD group, n=74). ULD corresponded to sleep apnea (SA; n=12), Chronic obstructive pulmonary disease (COPD; n=31), asthma (n=20), diffuse interstitial lung disease (n=3), bronchiectasis (n=4) and COPD/SA (n=2). Long-term oxygen or home MV were required in 11 cases. Obesity was more frequent in ULD group (45% vs 39%; p=0.01). COVID clinical presentation was similar between both groups (cough, dyspnea, struggle signs, respiratory rate, digestive signs, myalgia, anosmia). Pulmonary lesions on the first thoracic CT-scan performed during hospitalization were significantly more extensive in the no ULD group (p=0.05). Ventilator parameters and lung mechanics were similar between both groups (Table 1). The occurrence of ARDS, thrombo-embolic events, and septic shock was comparable between both groups. Requirement and duration of MV did not differ (55% vs 45%; p=0.25 and 7.84 vs 8.97 days; p=0.52, respectively), but mortality rate was significantly higher in ULD group (n= 47, 63.5% vs n=31, 41.9%; p=0.008).","contentDiscussion":"","contentConclusion":"unexpectedly, we didn’t find any major difference regarding the clinical presentation, severity scores at admission, and the MV requirement between critical COVID-19 patients with ULD versus without ULD, however, the severity of CT scan injury and respiratory parameters were greater in no ULD group. The mortality rate was more marked in the ULD group.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHABARA Racha"},{"id":99486,"num":"A34476GM","reference":"FC-152","title":"Characteristics and prognosis of mechanical ventilated patients with SARS CoV2 pneumonia: a prospective analysis of 143 patients","formatedAuthors":"Giulia MORATELLI (1), Kais REGAIEG (1), Sabrine NAKAA (1), Nesrine FRAJ (1), Myriam KALLEL (1), Amir AL HARACH (1), Laure GAZAIGNE (1), Dany GOLDGRAN-TOLEDANO (1)
(1) Groupe Hospitalier Intercommunal Le Raincy Montfermeil, Montfermeil, FRANCE","contentIntroduction":"The aim of this study was to describe the epidemiological and clinical characteristics of patients with SARS CoV 2 pneumonia mechanically ventilated admitted to an ICU of a general care center in France and to identify risk factors associated with mortality.","contentPatientsMethods":"We performed a prospective cohort study of patients admitted into ICU from Mars 2020 to February 2022 for SARS CoV2 pneumonia and mechanically ventilated","contentResultats":"During the study period, we have included 143 patients and the mortality rate was 51% (n = 72). Median stay in ICU was 16 (1 -149) days and median delay to ICU hospitalization was 8 (1 – 24) days. Median age was 62 (29 – 84), sex ratio M/F was 1.94 and median SAPS was 33 (18 – 75). Median BMI was 30 (19 - 68). 64% of patients had hypertension (n = 91) and 42% (n=60) were diabetics. Patients presenting an acute kidney failure were 36% (n = 51) and 26% of them (n = 37) have needed a renal replacement therapy. 82% of patients (n = 117) had non-invasive ventilation and 79% (n = 113) had high flow nasal oxygen as first line therapy. Median duration of ventilation was 12 days (1 – 47), 47% of patients (n = 67) were extubated and 7,7% (n = 11) have needed ECMO. 85% (n = 122) have needed at least one ventral decubitus. 85% of patients (n =122) have needed catecholamine. 73% of patients (n =105) had ventilatory acquired pneumonia, 17% (n =25) had thrombotic complications while 23% (n =33) had hemorrhagic complications. 37% of patients (n =53) have received dexamethasone 6 mg/day for ten days, 37% (n = 53) have received dexamethasone 0,1 mg/Kg/days for ten days and 15% (n = 22) of them have received bolus of methylprednisolone 250mg/days for three days as rescue therapy. Tocilizumab was administrated to 9,8% of patients (n = 14). \n In the univariate analysis, risk factors associated with mortality were age, hypertension, SAPS II, AKI, chronic renal disease, the use of catecholamine and hemorrhagic complications.\n In the multivariate analysis, only age (OR 1.09 [1.04; 1.14], p<0.001) was associated with mortality","contentDiscussion":"","contentConclusion":"The mortality of patient mechanically ventilated with SARS CoV 2 pneumonia associated is very high. Others studies are necessary to determine risk factors associated with mortality.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MORATELLI Giulia"},{"id":99487,"num":"A34571BD","reference":"FC-153","title":"Is there a benefit to high-flow nasal cannula therapy in COVID-19 critically ill patients?","formatedAuthors":"Khaoula BEN ISMAIL (1,4), Boudour BEN DHIA (1,4), Imen TALIK (1,4), Fatma ESSAFI (1,4), Aida BAYOUDH (2,4), Ilhem FESSI (2,4), Tahany JERBI (3), Mariem CHKIRBENE (3), Takoua MERHBENE (1,4)
(1) Service de réanimation Médicale Hôpital Régional de Zaghouan, Zaghouan, TUNISIE ; (2) Service De Pneumologie Hopital Regional de Zaghouan, Zaghouan, TUNISIE ; (3) Département de pharmacie de l'hôpital régional de Zaghouan , Zaghouan, TUNISIE ; (4) Faculté de médecine de tunis,Université Tunis El Manar, Tunis, TUNISIE","contentIntroduction":"During COVID-19 pandemic, high-flow nasal cannula therapy (HFNC) has been proposed as a ventilation device aiming to improve oxygenation and respiratory mechanic. However, its effectiveness has not been clearly demonstrated in terms of secondary need to invasive ventilation and reduction of morbidity and mortality.\n Aims: To evaluate efficacy and safety of HFNC in management of non-hypercapnic acute respiratory failure secondary to SARS-CoV-2 infection.","contentPatientsMethods":"Prospective, monocentric, interventional study conducted in the medical intensive care unit (ICU) of Zaghouan, Tunisia; over 18 months (March 2020 - September 2021). Patients admitted for non-hypercapnic acute respiratory failure secondary to SARS-CoV-2, aged over 18 years, were included. Two groups were identified G1= patients who received HFNC alone or in combination with other non-invasive ventilation device and Group G2= patients who received conventional oxygen therapy in combination with non-invasive ventilation. We compared demographic, clinical, paraclinical and evolutionary data.","contentResultats":"181 patients were included. HFNC was used in 111 patients (61.3%). It was associated to non-invasive ventilation and awake prone position in 83% and 92 % of cases respectively. On admission, the two groups were comparable in terms of demographic characteristics, clinical presentation and initial severity. Mean P/F ratios were 152 and 139 mmHg respectively (p=0.08). Comparison of outcome parameters showed that G1 patients need less likely invasive mechanical ventilation (27% vs 56.4%, p=0.002) and developed fewer healthcare-associated infections and barotrauma (42.1% vs 62%, p=0.03; 12% vs 22%, p=0.03). Mortality was significantly lower in G1 (22% vs 39%; p=0.02). Duration of total mechanical ventilation was comparable between two groups but length of ICU stay was longer in G1. Occurrence of pulmonary fibrosis was more frequent in G1 (18% vs 6%, p=0.02). Multivariate analys showed that use of HFNC was a protective factor against need to invasive ventilation (OR=0,42; 95% IC [0.3-0.7], p=0,03) and healthcare-associated infections (OR=0,8; 95% IC [0.1-0.7] ,p=0,04 ).","contentDiscussion":"","contentConclusion":"In this preliminary study, it appears that HFNC seems to be beneficial in severe COVID-19 patients. Further studies are needed to confirm this contribution","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BEN ISMAIL Khaoula"},{"id":99488,"num":"A34575MJ","reference":"FC-154","title":"Risk factors of high-flow nasal canula oxygen therapy failure in critically ill patients with COVID-19","formatedAuthors":"Zakaria AIT HAMOU (2), Nathan LEVY (2), Julien CHARPENTIER (2), Jean-Paul MIRA (2), Matthieu JAMME (3), Mathieu JOZWIAK (1)
(1) CHU de Nice, hôpital l'Archet 1, Nice, FRANCE ; (2) Hôpitaux Universitaires Paris centre, APHP, Hôpital Cochin, Paris, FRANCE ; (3) Hôpital Privé de l’Ouest Parisien, Trappes, FRANCE","contentIntroduction":"The use of high-flow nasal oxygen therapy (HFNO) as first-line support ventilatory might be associated with lower intubation rate in critically-ill COVID-19 patients. However, risk factors of HFNO failure remain to be determined.","contentPatientsMethods":"In this retrospective study, we included all consecutive COVID-19 patients admitted in our 24-bed intensive care unit (ICU) in the first (Mars-May 2020) and second (August 2020- February 2021) pandemic waves. Patients with limitations for intubation were excluded. Risk factors of HNFO failure were identified through a landmark time-dependent cause-specific Cox model. The ability of the 6-hour ROX index to detect HFNO failure was assessed by generating receiver operating characteristic (ROC) curve. The impact of HFNO use was analyzed in the whole cohort and after constructing a propensity score. The relationship between HFNO use and risk of intubation was assessed with a Cox cause-specific analysis.","contentResultats":"Overall 200 patients were included: HFNO was used in 114(57%) patients, non-invasive ventilation (NIV) in 25(12%) patients and 145(72%) patients were intubated with a median delay of 0(0-2) days after ICU admission. Patients with HFNO were older and less severe than those without HFNO and 78(68%) had HFNO failure. Patients with HFNO failure had a higher ICU mortality rate (34 vs. 11%, p=0.02) than those without. At landmark time of 48 and 72 hours, SAPS-2 score, extent of CT-Scan abnormalities >75% and HFNO duration (CSH=0.11, 95% CI(0.04-0.28), per +1 day, p<0.001 at 48h and CSH=0.06, 95% CI(0.02-0.23), per +1 day, p<0.001 at 72h) were associated with HFNO failure. The 6-hour ROX index was lower in patients with HFNO failure but could not reliably predicted HFNO failure with an area under ROC curve of 0.65 (95%CI(0.52-0.78), p=0.02). In the matched cohort, there was a negative association between HFNO use and the risk of intubation (CSH=0.32, 95% CI(0.19-0.57), p<0.001).","contentDiscussion":"","contentConclusion":"In critically-ill COVID-19 patients, while HFNO use as first-line ventilatory support was associated with a lower risk of intubation, more than half of patients had HFNO failure. The risk of HFNO failure could not be predicted by the 6-hour ROX index but decreased after a 48-hour HFNO duration.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LEVY Nathan"},{"id":99489,"num":"A34380TU","reference":"FC-155","title":"Endotracheal intubation rate is lower in critically-ill SARS-CoV-2 patients requiring high-flow nasal oxygen receiving additional face-mask noninvasive ventilation: a retrospective bicentric cohort with propensity score analysis","formatedAuthors":"Tomas URBINA (1), Alexandre ELABBADI (2), Paul GABARRE (1), Naïke BIGÉ (1), Matthieu TURPIN (2), Vincent BONNY (1), Cyrielle DESNOS (2), Jean-Luc BAUDEL (1), Jean-Rémi LAVILLGRAND (1), Geoffroy HARIRI (1), Muriel FARTOUKH (2), Bertrand GUIDET (1), Guillaume DUMAS (3), Guillaume VOIRIOT (2), Hafid AIT-OUFELLA (1)
(1) Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, FRANCE ; (2) Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, FRANCE ; (3) Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, FRANCE","contentIntroduction":"SARS-CoV-2 pneumonia is responsible for unprecedented numbers of acute respiratory failure requiring invasive mechanical ventilation (IMV). We aimed to assess whether adding face-mask noninvasive ventilation (NIV) to high-flow nasal oxygen (HFNO) was associated with a reduced need for endotracheal intubation.","contentPatientsMethods":"This retrospective cohort study was conducted from July 2020 to January 2021 in two tertiary care intensive care units (ICUs). Patients admitted for laboratory confirmed SARS-CoV-2 infection with acute hypoxemic respiratory failure requiring HFNO with or without NIV were included. The primary outcome was the rate of endotracheal intubation. Secondary outcomes included day-28 mortality, day-28 respiratory support and IMV free days, ICU and hospital length-of-stay. Sensitivity analyses with both propensity score matching and overlap weighting were used.","contentResultats":"128 patients were included, 88 (69%) received HFNO alone and 40 (31%) received additional NIV. Additional NIV was associated with a reduced rate of endotracheal intubation in multivariate analysis (53 (60%) vs 15 (38%), HR=0.46 (95%CI, 0.23-0.95), p=0.04) (Figure 1). Sensitivity analyses by propensity score matching (HR=0.45 (95%IC, 0.24-0.84), p=0.01) and overlap weighting (HR=0.52 (95% CI, 0.28-0.94), p=0.03) were consistent. Day-28 mortality was 25 (28%) in the HFNO group and 8 (20%) in the NIV group (HR=0.75 (95%CI, 0.15-3.82), p=0.72). NIV was associated with higher IMV free days (20 (0-28) vs 28 (14-28), p=0.015). All sensitivity analyses were consistent regarding secondary outcomes.","contentDiscussion":"","contentConclusion":"Need for endotracheal intubation was lower in critically-ill SARS-CoV-2 patients receiving face-mask noninvasive mechanical ventilation in addition to high-flow oxygen therapy. Further prospective trials are needed before this treatment can be generally recommended.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1209","session":"FLASH COM - COVID-19 : de l'épidémiologie au pronostic 2","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"URBINA Tomas"},{"id":99490,"num":"A34389JP","reference":"FC-156","title":"Patient outcomes in a respiratory weaning unit after prolonged intensive care: a review of 2021","formatedAuthors":"Jean-Baptiste PERETOUT (1), Karim NSSAIR (1), Razach ABDALLAH (1), Raphael LEPECQ (1), Laurence DONETTI (1), Mohamed LAISSI (1), Gérald CHOUKROUN (1)
(1) Hôpital Forcilles - Fondation Cognacq-Jay, Férolles-Attilly, FRANCE","contentIntroduction":"Weaning units have shown their value in the management of tracheostomized patients after prolonged intensive care1. The global and multidisciplinary approach contributes to accelerate and improve weaning2. The objective of this study is to describe the results of weaning and decannulation in these patients.","contentPatientsMethods":"This is a retrospective, descriptive study in a respiratory weaning unit over the year 2021. All patients hospitalized in the weaning unit were included. Demographic characteristics and weaning unit outcomes were collected. All inpatients with complete data were analyzed. The analysis was completed by a subgroup analysis of patients on 24-hour spontaneous ventilation at admission and patients still with mechanical ventilation (MV) at admission (intermittent or continuous).","contentResultats":"In 2021, 144 patients were admitted. A total of 134 patients were analyzed with male 70%, age 63 ± 12 years, COVID 70%. The main diagnosis of admission on intensive care unit was acute respiratory failure in 84%. The goal of admission on weaning unit was: ventilatory and tracheostomy weaning in 63% and tracheostomy weaning in 37%.\n On admission, patients were on 24-hour spontaneous ventilation in 34% (n=46) and on mechanical ventilation in 66% (n=88): 66% intermittent MV (n=58); 34% continuous MV (n=30).\n In overall patients, 24-hour spontaneous ventilation was achieved in 8.4 ± 12.8 days, decanulation in 20.4 ± 15 days and the length of stay was 30.7 ± 18.3 days.\n The overall decanulation success rate was 88%.\n Subgroup analyses are presented in Table I.","contentDiscussion":"","contentConclusion":"Patients with prolonged intensive care and complex medical needs treated at a specialized weaning unit had high quality weaning and decannulation rates. This was achieved with a multidisciplinary team approach to continued intensive care and simultaneous rehabilitation with physiotherapists, speech therapists, nutritionists…\n Cares in a weaning unit remains relevant despite a prolonged stay in ICU during this COVID period.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Boles JM, Bion J, Connors A, Herridge M, Marsh B, Melot C, Pearl R, Silverman H, Stanchina M, Vieillard-Baron A, Welte T. Weaning from mechanical ventilation. Eur Respir J. 2007 May;29(5):1033-56","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Nelson JE, Cox CE, Hope AA, Carson SS. Chronic critical illness. Am J Respir Crit Care Med. 2010 Aug 15;182(4):446-54","presentateur":"PERETOUT Jean-Baptiste"},{"id":99491,"num":"A34311MS","reference":"FC-157","title":"Pulmonary consequences at 12 months of a severe COVID-19 infection","formatedAuthors":"Melanie SAINT JOUAN (1), Tristan MORICHAU-BEAUCHANT (1), Jean Michel MAILLET (1)
(1) Centre Cardiologique du Nord, Saint Denis, FRANCE","contentIntroduction":"Two years after the first wave of the SARS-CoV-2 epidemic in France, the pandemic is still active, but the data about the long-term consequences of the pulmonary function are limited.\n \n In this context, we have carried out an evaluation of the pulmonary function of patients who survived severe ARDS secondary to SARS-CoV-2 infection, one year after their hospitalization.","contentPatientsMethods":"We have carried out a single-center prospective and descriptive cohort study with patients who survived severe ARDS during the first wave of the pandemic between the months of March to April 2020. This study took place from April 2021 to July 2021.\n The patients included in this study had required a prolonged stay (more than seven days) in intensive care unit and were under mecanical invasive ventilation for more than three days during the first wave of the pandemic.\n The main goal was to assess the lung function. The assessment included a chest CT-scan, pulmonary function tests, a 6-minute walk test, and an evaluation of patient's quality of life depending on their respiratory symptoms using the St George's respiratory survey. The patients were hospitalized for a day in the center for these exams.","contentResultats":"30 patients were included in the study, of which 8 patients were under veno-venous ECMO during their hospitalization.\n \n The chest CT-scans revealed few ground-glass opacities, with a median scanographic severity score of 1 out of 25 [IQR 0-2.5]; 43% of the CT-scans were normal. On the pulmonary function tests 32% of patients had restrictive ventilatory defects, and 45% of patients had diffusing capacity of the lungs for carbon monoxide impairment. The impact on functional abilities assessed by the six-minute walk test resulted in a distance traveled less than normal in 33% of patients. The results of the St George's Hospital survey showed that quality of life was altered, with results similar to those of ARDS survivors.","contentDiscussion":"","contentConclusion":"This is the first cohort study assessing long-term respiratory sequelae only patients who suffered from severe COVID-19 infection, one year after ICU discharge. The majority had abnormal lung function tests and residual parenchymal abnormalities on CT scans. Diffusing capacity of the lungs for carbon monoxide and total lung capacity were impaired in one-third of patients. Limitation of physical activity has been documented.\n Despite, they were autonomous and living at home, which is encouraging for the functional prognosis of patients with severe forms of COVID-19.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SAINT JOUAN Melanie"},{"id":99492,"num":"A34597MO","reference":"FC-158","title":"Interest of non-invasive ventilation in the prevention of post-extubation respiratory distress in medical intensive care.","formatedAuthors":"Mourad OUALI (1), Redha Malek HAMIDI (1)
(1) Faculté de médecine; Centre hospitalo-universitaire Béni Messous, Alger, ALGERIE","contentIntroduction":"The failure of extubation defined by the need for recourse to reintubation of the patient less than 72 hours later is correlated with excess mortality as well as an increase in the length of stay in intensive care, this failure is often due to the occurrence acute respiratory failure after extubation.","contentPatientsMethods":"In order to assess the impact of non-invasive prophylactic intermittent ventilation on the frequency of occurrence of post-extubation respiratory distress, a comparative, descriptive, single-center and randomized study was conducted in a medical intensive care unit over a period of two years (2018-2020). 73 patients hospitalized in intensive care, put on invasive mechanical ventilation for more than 24 hours and extubated after having tolerated the spontaneous ventilation challenge well, were randomized and randomized to receive non-invasive intermittent ventilation for 24 hours in a group then conventional oxygen therapy and in another group conventional oxygen therapy alone. The main endpoint was the frequency of occurrence of respiratory distress after extubation.","contentResultats":"The results allowed us to observe a significant decrease in the frequency of occurrence of post-extubation respiratory distress in patients in the NIV group compared to patients in the conventional oxygen therapy group (7.9% VS 28.6%; P = 0.02), as well as a reduction in the reintubation rate (7.9% in the NIV group versus 20% in the oxygen only group; p = 0.13). The length of stay in resuscitation was longer in patients who presented with acute respiratory failure (25.77 ± 5.0 days in the respiratory distress group versus 15.37 ± 0.85 days in the group without respiratory distress; p = 0.001) but without significant difference between the NIV group and the conventional Oxygen group, p = 0.64. Post-extubation respiratory distress was correlated with significant excess mortality with 46.2% mortality in the group of patients who presented with respiratory distress after extubation versus no death in the group of patients who did not develop this complication, p <0.001. In contrast, we did not notice a significant difference in mortality between the two study groups.","contentDiscussion":"","contentConclusion":"Our study has made it possible to highlight all the interest that NIV can bring in the period following the planned extubation of patients in intensive care, by demonstrating a significant reduction in the frequency of occurrence of acute respiratory failure after extubation, the reduction in the rate of reintubation as well as the shortening of the length of stay in intensive care.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Xu Z, Li Y, Zhou J, Li X, Huang Y, Liu X, et al. High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis. Respir Res. 2018;19(1):202.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Zhu Y, Yin H, Zhang R, Ye X, Wei J. High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation: a systematic review and meta-analysis. Crit Care. 2019;23(1):180.","presentateur":"OUALI Mourad"},{"id":99493,"num":"A34471GT","reference":"FC-159","title":"One-year follow-up of patients and relatives after severe COVID-19 related ARDS treated in the intensive care unit.","formatedAuthors":"Guillaume THIERY (1), Raphael LAURENT (1), Patricia CORREIA (1), Eric EZINGEARD (1), Diconne ERIC (1), Raphael LACHAND (1), Sophie PERINEL-RAGEY (1), Franklin BRUNA (1), Magali DIREZ (1), Elodie ROUSSET (1), Nadège CURTO (1), Emilie PINATEL (1), Céline CHARRA (1), Gérald PHILIBERT (1), Pierre Alban GUENIER (1)
(1) CHU de Saint Etienne, St Priest En Jarez, FRANCE","contentIntroduction":"Severe COVID-19 often leads to prolonged stay in the ICU. Survivors may experience physical and psychological sequelea. The impact on relatives is also considerable. The aim of this study is to evaluate physical and psychological condition of severe COVID-19 patients 1 year after ICU discharge and to assess the psychological impact on their relatives.","contentPatientsMethods":"All consecutive patients admitted to the ICU for COVID-19 related ARDS from March 5th to November 21st 2020 were included in our post-ICU follow-up program, if their ICU stay was ≥ 7 days. They were invited to attend a post-ICU consultation, which consisted of a 2-hour face to face meeting with a senior ICU physician and an ICU nurse. Before the consultation, they were asked to complete four self-evaluation questionnaires: Hospital Anxiety and Depression scale (HADS), Revised Impact of Event Scale (IES-R), Short-Form General Health Survey (SF-12) and Inconforts des Patients de REAnimation (IPREA). In addition, a CT-scan and basic laboratory tests were performed before the consultation. Patients were invited to be accompanied by a close relative, who was also invited to fill HADS and IES-R questionnaires.","contentResultats":"Among the 170 patients admitted to the ICU, 127 patients survived to the hospital and 81 met inclusion criteria. Twenty-five patients did not respond or declined. The remaining 56 patients attended the consultation. The median age was 66 (IQR 57-71), 79% had been mechanically ventilated. Duration of ICU and hospital (including rehabilitation) stays were 19 (IQR 12-26) and 49 (IQR 26-64) days respectively.\n Severe symptoms of anxiety, depression and PTSD are reported on table 1. The most frequently reported discomforts were limited visiting hours, sleep deprivation, anxiety, being tied down and noise.\n Fifty nine percent of the patients resumed their hobbies at one year. Five (28%) of the 18 pre-ICU employed patients fully returned to work.\n Shortness of breath was reported by 64% of the patients, although among the 42 CT scan performed, only 7 (16%) showed persistent abnormalities. Symptoms of fatigue were reported by 63% of the patients, and physical functioning was reduced with a physical component of SF-12 score at 44.","contentDiscussion":"","contentConclusion":"One year after their ICU discharge, the psychological impact of severe COVID-19 for patients treated in the ICU is high, and is even higher for relatives. A majority of patients present still with persistent respiratory symptoms although most of them have a lung CT scan normal.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"THIERY Guillaume"},{"id":99494,"num":"A34400KS","reference":"FC-160","title":"Tracheostomy in patients admitted due to COVID-19.","formatedAuthors":"Khedher SANA (1), Rashed ALI (1), Nawar ELDHAWI (1), Majid Al Dossari HASSAN (1)
(1) AFH Wady addawassir, Riadh, ARABIE SAOUDITE","contentIntroduction":"During the COVID-19 pandemic, the world has seen an increase in the number of critically ill patients who require invasive mechanical ventilation (IVM). ventilation is certainly a challenge and tracheostomy was one of the management strategies.","contentPatientsMethods":"We reviewed the medical records of all patients admitted to our intensive care, between April 01,2020 and August 31,2021, suffering from acute respiratory syndrome due to SARS COV2 and requiring tracheostomy after IMV. The objective was to determine the rate as well as the clinico-epidemiological profile of tracheotomized patients.","contentResultats":"A total of 96 patient admitted during this period. Fourteen 40 (41%) had acute respiratory failure and needed IMV support. Ten (25%) had a tracheostomy, they were predominantly male (55%) with mean of age 70+-15 year and all having at least one comorbidity. Mean SAPSII score on ICU admission was 34+-16. The average time from endotracheal intubation to tracheostomy was 20+-8 days. Failure to weaning (50%) was the most common indication, followed by respiratory failure (30%), hypersecretion (10%), and neuromyopathy (10%). 50% were liberated from ventilator, 20% have been decannulated and all patient have been discharged alive. Here we have opted open surgical technique. two episodes of local bleeding were observed. No transmission has occurred among health workers","contentDiscussion":"Several previous studies have shared their experiences and have shown that tracheostomy done in the correct manner is safe for the heal care workers and provides good recovery for the severely ill with SARSCO2 pneumonia.","contentConclusion":"Use of tracheostomy can be adopted as essential clinical strategy for managing critical ill patients with SARS COV 2 who require IVM.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Tiffany N. Chao et al. Outcomes After Tracheostomy in COVID-19 Patients. Ann Surg 2020;272:e181–e186.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Zhou F, et al. Clinical course and risk factors for mortality of adult In patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062.","presentateur":"SANA Khedher"},{"id":99495,"num":"A34542RT","reference":"FC-161","title":"Clinical features, ventilatory management and outcomes of COVID-19 related ARDS in a medical ICU","formatedAuthors":"Radhouane TOUMI (1,2), Khaoula MEDDEB (1,2), Nabil BOUGUEZZI (1), Hajer ZOUARI (1), Iyed MAATOUK (1), Dhouha HAMDI (1), Imen BEN SAIDA (1,2), Mohamed BOUSSARSAR (1,2)
(1) Medical Intensive Care Unit, Farhat Hached University Hospital, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, University of Sousse, Sousse, TUNISIE","contentIntroduction":"The COVID-19 pandemic took the world by storm defying physicians in many aspects; going from health systems responsiveness to diagnosis and treatment, especially with the introduction of concepts such as “happy hypoxemia” that modulated intensivists’ approach to ventilatory management. The Aim of the present study is to describe clinical features, ventilatory management and outcomes of critically ill adults admitted in for COVID-19 related ARDS.","contentPatientsMethods":"This is a descriptive retrospective study carried out in a 12-bed medical intensive care unit (MICU) of a University Hospital from March 2020 to September 2021. All patients admitted for a critical COVID-19 related ARDS were included. Data on patients’ characteristics at ICU admission, clinical presentation, ARDS and COVID-19 severity, ventilatory management, ventilatory settings, airways pressures and outcomes were collected. The database served to inquire about several aspects of COVID-19 related ARDS that will be discussed through a series of studies.","contentResultats":"During the study period, 442 patients were admitted for COVID-19 pneumonia, 409(92.6%) presenting severe to critical COVID-19. They were aged, 64[54-71] years; male, 279(63.1%); had hypertension, 197(44.6%) ; diabetes mellitus, 187(42.3%) and obese; 172(38.9%). At admission, moderate to severe acute respiratory failure, 340(76.9%); median SAPS II, 28[22-35]; moderate to severe ARDS, 400(90.5%); mean P/F ratio, 114[84-157]. Chest CT-scan performed in 268(60.6%) patients, 163(60.8%) had more than 50% of pulmonary parenchyma lesions. Ventilatory support was required in 439(99.3%); immediate IMV at admission, 33(7.5%); HFNC, 334(77.8%); median HFNC duration, 4[2-7] dys; NIV and CPAP as rescue therapy to avoid intubation, respectively, 52(11.8%); 10(2.2%), median NIV starting day, day 1[0-2]; median NIV duration, 2[1-33] dys; CPAP starting day, day 3[1-3]; median CPAP duration, 2[1-4] dys. Non invasive procedures failure rate, 41.2%; median delay of intubation, 3[2-5] dys; overall IMV, 215(48.6%); median overall IMV starting day, day 2[1-4]; median IMV duration, 8[5-12] dys. Overall mortality was at 211(47.7%), 130(37.8%) for patients on HFNC, 93(72.7%) when patients were switched to NIV and 180(83.72%) when on IMV.","contentDiscussion":"","contentConclusion":"The present study demonstrated a poor prognosis in mechanically ventilated patients with COVID-19 related ARDS. HFNC was prioritized for most patients. NIV was used as a rescue therapy in an attempt to avoid intubation.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1210","session":"FLASH COM - COVID-19 : sevrage et pronostic à long terme","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUGUEZZI Nabil"},{"id":99496,"num":"A34690is","reference":"FC-162","title":"Doses of dexaméthasone in Covid-19 patients","formatedAuthors":"Ines SDIRI (1,2), Nizar FITOUHI (2), Amira DRIDI (2), Rim LAROUI (1), Sonia OUERGHI (2), Tahar MESTIRI (2)
(1) hopital Circonstance menzah , Tunis, TUNISIE ; (2) abderahmen memi ariana , Ariana, TUNISIE","contentIntroduction":"The SARS-CoV-2 induces both systemic and localized immune response leading to increased inflammation. Severe pulmonary lesions in SARS-Cov-2 ARDS has been found to be associated with severe inflammatory cell infiltration and elevated pro-inflammatory cytokines(1). Dexamethasone decreases mortality in patients with severe coronavirus disease 2019 (COVID-19) and has become the standard of care(2). The role of dexamethasone in the high incidence of ventilator-associated pneumonia observed in intensive care units (ICUs) deserves to be investigated.","contentPatientsMethods":"We conducted a retrospective study in an intensive care unit including critically ill patients with confirmed SARS-COV2 infection between January 2021 and December 2021. We compared two different doses of dexamethasone (6mgx3 per day versus 6 mg per day) given intravenously over 10 days. Secondary, our population was divided into two groups: those who received 6mg*3 (group 1) and those who received only 6mg (group 2). These two groups were matched on age, gender, SAPSII and APACHE scores, severity of acute respiratory distress syndrome on admission and clinical severity.","contentResultats":"We evaluated 323 patients with COVID-19 admitted to our institution. The median age was 57 [25–85] years and 53,6% of patients were male. Among these patients, 37,3% had hypertension, 33,1% had diabetes and 12,1 % had chronic lung disease. On admission, all patients presented a respiratory distress with CT injury superiors of 50% in 49,7% of patients. 57, 7% patients were intubated during hospitalisation. ICU length of stay was 9±8 days. ICU mortality was 45%. All patients received dexamethasone. 77,2% were included in group 1 and 20,5% patients in group 2. There was no difference in acute kidney injury rate (17,6% vs. 3,4% ; p=0,275) or the need of mechanical ventilation (59,5% vs. 45,4% ; p=0,11) between the two groups. We noticed a higher incidence of nosocomial infection without signification (61,1% vs. 45,8%; p=0.095). However, in the higher dose dexamethasone group, we contented a higher rate of mortality not significant (48,3% vs. 29,1%; p=0.059). Besides, we noted more hyperglycemia and hypokalemia in the group 1 ((53% vs. 34%; p=0.04), (12% vs. 6%; p=0.039)).","contentDiscussion":"","contentConclusion":"Different dose of corticosteroids seems to increase the rate of nosocomial infection and do not affect mortality. However, the high-dosage group patients exposed patients with severe COVID-19 to more metabolic complications.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Maskin LP, Olarte GL, Palizas F, Velo AE, Lurbet MF, Bonelli I, et al. 26 août 2020;21","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"J Biol Regul Homeost Agents. août 2020;34","presentateur":"SDIRI Ines"},{"id":99497,"num":"A34702is","reference":"FC-163","title":"The impact of solumedrol in patients with COVID-19 related acute respiratory distress syndrome (ARDS)","formatedAuthors":"Ines SDIRI (1), Nizar FITOUHI (1), Amira DRIDI (1), Sana DORGHAM (1), Sonia OUERGHI (1), Tahar MESTIRI (1)
(1) hopital ariana abderahmen memi, Sfax, TUNISIE","contentIntroduction":"Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. The aim of our study was to evaluate the impact of methylprednisolone boli (1) on the prognosis of patients admitted to the ICU for covid 19 pneumonia.","contentPatientsMethods":"A retrospective study in intensive care unit of circumstance hospital over the period from January to September 2021. All admitted patients were systematically put on dexamethasone intravenously for 10 days, some of them had a stagnant respiratory status during the hospitalisation, received a bolus of solumedrol 5 days in a row, at a dose of 250mg/d and followed by hydrocortisone hemisuccinate at a dose of 1mg/kg/d of methylprednisolone equivalent with progressive digression over 15 days, according to the clinician's judgement, ensuring the absence of concomitant infection. Secondary, our population was divided into two groups: those who received solumedrol (group 1) and those who received only dexamethasone (control group). These two groups were matched on age, gender, SAPSII and APACHE scores, severity of acute respiratory distress syndrome on admission and clinical severity.","contentResultats":"Our study population included 82 patients, 41 in each group. The two groups were matched for age (p=0.9), gender (p=1), and different comorbidities (obesity, p=0.19, cardiovascular history p=0.009 and respiratory history p=0.3). At admission, 35 patients (92%) in group 1 had moderate to severe ARDS (p=0,9). However, the solumedrol group had a more severe clinical presentation at admission: Oxygen saturation on admission (89.5%±9 versus 92%±5 in the control group, (p=0.02); more signs of struggle (15 patients versus 8 in the control group, p=0.07). Solumedrol administration was performed within a median of 4 days [2-6], with respiratory worsening occurring within a median of 4±3 days (p=0,05). The use of invasive mechanical ventilation was more frequent in the G1 (25 patients versus 20, p=0,008). The occurrence of nosocomial infection was more frequent in the G1 (31 vs. 21 patients, p=0.0001). The duration of invasive mechanical ventilation, length of stay were comparable between the two groups (p=0.3 and p=0.08 respectively). The prescription of bolus Solumedrol was associated with higher rate of mortality (69% G1 vs. 45%; p=0,005) more shock complication (p=0.004)","contentDiscussion":"","contentConclusion":"Patients who received Solumedrol had a more severe clinical presentation, with more invasive mechanical ventilation, more nosocomial infection and higher rate of mortality(2). A randomized study is needed to assess the efficacy of Solumedrol compared with dexamethasone.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Pinzón MA, Ortiz S, Holguín H, Betancur JF, Cardona Arango D, Laniado H, et al.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Edalatifard M, Akhtari M, Salehi M, Naderi Z, Jamshidi A, Mostafaei S, et al.","presentateur":"SDIRI Ines"},{"id":99498,"num":"A34587IZ","reference":"FC-164","title":"therapeutic plasma exchange in patients with covid-19 pneumonia in intensive care unit: cases series","formatedAuthors":"Ikram ZAID (1), Ounci ESSAAD (1), Ghizlane EL AIDOUNI (1), Mohammed AABDI (1), Samia BERRICHI (1), Salma TAOUIHAR (1), Manal MARBOUH (1), Houssam BKIYER (1), Naima ABDA (1), Brahim HOUSNI (1)
(1) centre hospitalier universitaire Oujda, Oujda, MAROC","contentIntroduction":"COVID 19 pneumonia can lead to an inappropriate inflammatory response, and can be complicated by acute respiratory distress syndrome, multivisceral failure with a high mortality rate.\n Objective of this study is to observe the effect of therapeutic plasma exchange on the excessive inflammatory response.","contentPatientsMethods":"In this study, we included 7 confirmed cases of COVID-19 in the intensive care unit (ICU). COVID-19 cases were confirmed by RT PCR (reverse transcription?polymerase chain) and CT (computerized tomography) imaging according to WHO guidelines. Therapeutic plasma exchange was performed decrease cytokine storm-induced ARDS (Acute respiratory distress syndrome). Inflammation marker assays were performed before and after therapeutic plasma exchange to assess its efficacy.","contentResultats":"Levels of inflammatory cytokines (IL-6) and acute phase response proteins, including ferritin and CRP, were elevated before therapeutic plasma exchange.\n After therapeutic plasma exchange, levels of acute phase reactants, inflammatory mediators, were significantly reduced (p < 0.05).","contentDiscussion":"","contentConclusion":"Our data suggest that therapeutic plasma exchange reduces the inflammatory response in patients with severe COVID-19 not undergoing mechanical ventilation. Further studies are needed to explore the efficacy of therapeutic plasma exchange in patients with COVID-19.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ZAID Ikram"},{"id":99499,"num":"A34466MR","reference":"FC-165","title":"Impact of corticosteroid use in critically-ill COVID-19 patients on mortality, intubation, and adverse events: a French multicenter study","formatedAuthors":"Matthieu RAYMOND (1), Aurélie LE THUAULT (1), Pierre ASFAR (2), Cédric DARREAU (3), Florian REIZINE (4), Gwenhaël COLIN (5), Charly DANO (6), Julien LORBER (7), Baptiste HOURMANT (8), Agathe DELBOVE (9), Aurélien FREROU (10), Jean MORIN (1), Pierre Yves ERGRETEAU (11), Philippe SEGUIN (4), Jean REIGNIER (1), Jean Baptiste LASCARROU (1), Emmanuel CANET (1)
(1) CHU de Nantes, Nantes, FRANCE ; (2) CHU d'Angers, Angers, FRANCE ; (3) CH du Mans, Le Mans, FRANCE ; (4) CHU de Rennes, Rennes, FRANCE ; (5) CHD La Roche sur Yon, La Roche Sur Yon, FRANCE ; (6) CH de Cholet, Cholet, FRANCE ; (7) CH de Saint Nazaire, Saint Nazaire, FRANCE ; (8) CHU de Brest, Brest, FRANCE ; (9) CH de Vannes, Vannes, FRANCE ; (10) CH de Saint Malo, Saint Malo, FRANCE ; (11) CH de Morlaix, Morlaix, FRANCE","contentIntroduction":"The use of corticosteroids is recommended for the management of critically-ill COVID-19 patients based on the results of the RECOVERY trial [1], which reported a reduced day-28 mortality in patients requiring oxygen therapy or mechanical ventilation. However, the effectiveness and safety of corticosteroids still remain a matter of debate.","contentPatientsMethods":"We conducted a multicenter observational study. All Covid-19 patients admitted in 13 ICUs from Pays-de-la-Loire and Bretagne regions between February 1st 2020 and December 31th 2020 were included. The main objective was to assess the impact of an early course of dexamethasone on day-28 mortality.","contentResultats":"Overall, 1058 patients were included of whom 644 (60.87%) were intubated. An early course of dexamethasone (dexamethasone group) was given to 611 (57.75%) patients while 447 (42.25%) patients did not receive an early course of dexamethasone (usual care group). Day-28 mortality was 15.4% in the whole population, 15.1% in the dexamethasone group, and 15.9% in the usual care group (p=0.63). On multivariable analysis, age (aHR 1.06 (1.03-1.08), p<0.001), SOFA score (aHR 1.15 (1.09-1.21), p<0.001), and immunocompromised status (aHR 1.62 (1.06-2.47), p=0.026) were associated with a higher risk of day-28 mortality while the use of dexamethasone had no impact (aHR 0.81 (0.57-1.15), p=0.245). The risk of intubation was reduced in the dexamethasone group compared to the usual care group. This result was confirmed after adjustment for respiratory rate, PaO2/FiO2 ratio, and respiratory support at ICU admission (standard oxygen vs high-flow oxygen or non-invasive ventilation) (aHR 0.48 (0.40-0.58), p<0.001). Ventilator-free days at day-28 were 22 [2;28] in the dexamethasone group and 15 [0;28] in the usual care group (p<0.001).Patients in the dexamethasone group had a higher risk of ventilator associated pneumonia than those of the usual care group (HR 1.24 (1.00-1.54), p=0.05), while there was no difference on the risk bloodstream infection (HR 1.23 (0.80-1.88), p=0.35), fungal infection (OR 0.64 (0.37-1.10), p=0.11) and gastrointestinal bleeding (OR 1.10 (0.58-2.09), p=0.77) between the 2 groups.","contentDiscussion":"","contentConclusion":"In our study, an early course of dexamethasone in critically-ill Covid-19 patients was not associated with a reduced day-28 mortality, but increased the risk of ventilator associated pneumonia compared to standard of care management. However, an early course of dexamethasone reduced the risk of intubation, increased the number of ventilator-free days at day-28, and was not associated with a higher risk bloodstream infection, fungal infection or gastro-intestinal bleeding.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"[1] RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, et al. Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report. N Engl J Med. 17 juill 2020","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"RAYMOND Matthieu"},{"id":99500,"num":"A34641JL","reference":"FC-166","title":"High dose steroids for persisting ARDS in critically ill COVID-19 patients treated with dexamethasone: a prospective observational multicentre study","formatedAuthors":"Julien LOPINTO (1), Romain ARRESTIER (1), Guillaume VOIRIOT (3), Tomas URBINA (2), Charles-Edouard LUYT (4), Raphael BELLAICHE (1), Taï PHAM (6), Zakaria AIT-HAMOU (7), Damien ROUX (5), Raphael CLERE-JEHL (9), Stéphane GAUDRY (8), Julien MAYAUX (4), Armand MEKONTSO DESSAP (1), Nicolas DE PROST (1)
(1) Hôpital Henri Mondor AP-HP, Créteil , FRANCE ; (2) Hôpital Saint Antoine AP-HP , Paris , FRANCE ; (3) Hôpital Tenon AP-HP, Paris , FRANCE ; (4) Hôpital Pitié Salpétrière AP-HP, Paris , FRANCE ; (5) Hôpital Louis Mourier AP-HP, Colombes , FRANCE ; (6) Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre , FRANCE ; (7) Hôpital Cochin AP-HP, Paris , FRANCE ; (8) Hôpital Avicenne AP-HP, Bobigny , FRANCE ; (9) Hôpital Civil de Strasbourg , Starsbourg , FRANCE","contentIntroduction":"Severe COVID-19 is responsible for acute respiratory distress syndrome (ARDS), requiring the use of invasive mechanical ventilation in 60% of cases. Short-term corticosteroid therapy (CTC) initiated in the acute phase of the infection reduces the 28-day mortality of patients on oxygen therapy or mechanical ventilation. In some cases, the evolution in intensive care is marked by the persistence of ARDS; the mechanisms generating this unfavorable development involve inflammatory processes and pulmonary fibro-proliferation. The impact of high-dose corticosteroid therapy has already been assessed in the field of persistent ARDS unrelated to SARS-CoV-2 but to date there is not data to assess the impact of such a strategy during severe COVID-19.","contentPatientsMethods":"We collected data from the prospective multicenter database ANTICOV involving 11 intensive care unit (ICU) of AP-HP. Eligible patients were admitted in ICU with pneumonia related to COVID 19 and were treated with initial CTC with dexamethasone. We compared patients receiving usual ICU care and patients receiving a secondarily high dose of CTC during ICU care (CTC group).","contentResultats":"Between September 2020 and March 2021, we enrolled 593 patients. 61 patients (12%) received secondarily high doses of CTC during ICU care. Median delay between dexamethasone and high dose of corticosteroids was 16 days [9-27.5].There was no between-group difference for median SOFA admission. ICU mortality was higher in the CTC group (48%) as compared with usual care (28%) (p=0.002). Invasive mechanical ventilation was performed in 359 (67%) patients with usual care and in 47 (77 %) patients in CTC group (p= 0.13). The median duration in days of mechanical ventilation and ICU length of stay was higher in the CTC group: respectively 16 [9-28] and 13 [6-27] vs 26.5 [19-40] and 31 [21-45] (both p < 0.001). The proportion of bacterial ventilator associated pneumonia was higher in the CTC group (69%) as compared with usual care (49%) (p =0.004). Fungal infection was documented in 40 (7.5%) with usual care and in 8 patients (13%) in CTC group (p= 0,132). ICU mortality in CTC group with fungal infection was 87.5%.","contentDiscussion":"","contentConclusion":"We found that 12 % of patient admitted in ICU for severe COVID 19 received a secondarily high doses of corticosteroids during ICU care. High doses CTC was associated with a higher mortality rate in ICU and higher duration of invasive mechanical ventilation and ICU stay. Propensity score will be made to assess the probability of CTC assignment conditional on observed baselines.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LOPINTO Julien"},{"id":99501,"num":"A34515LS","reference":"FC-167","title":"Efficacy of corticosteroids as rescue therapy for prolonged mechanically ventilated-COVID patients with suspected pulmonary fibroproliferation: an observational retrospective study","formatedAuthors":"Dima SIBLANI (1), Roxana-Maria STEFAN (1), Claire SROUR (1), Clément PALPACUER (1), Khaldoun KUTEIFAN (1), Laure STIEL (1)
(1) GHRMSA - hôpital Emile Muller, Mulhouse, FRANCE","contentIntroduction":"Pathophysiology of coronavirus disease 2019 (COVID-19) suggests a strong role of exaggerated immune response in the evolution to acute respiratory distress syndrome (ARDS). COVID- ARDS is characterized by its protracted course, lasting twice as long as ARDS of other origins. Persistent ARDS is characterized by ongoing inflammation, excessive pulmonary fibroproliferation (PFP), prolonged mechanical ventilation, and a substantial mortality. Corticosteroid treatment dampens the hyperinflammatory response and is prescribed as an adjunctive treatment for moderate and severe forms of COVID-19 pneumonia. Only rare data are available for patients with COVID requiring prolonged ventilation.\n In this retrospective study, we aimed to assess the efficacy of corticosteroids as rescue therapy in patients with persistent COVID-ARDS","contentPatientsMethods":"This observational retrospective study was conducted in one intensive care unit of a French general hospital including mechanically ventilated COVID-ARDS patients admitted between March 2020 and January 2022 who received high-dose of methylprednisolone (1-2mg/kg/day) for persistent COVID-ARDS after more than ten days of mechanical ventilation. Included patients exhibit at least one out of three criteria for suspicion of PFP changes: low lung compliance, fibrotic changes on Chest CT, or persistent hypoxemia. Endpoints were improvement of lung compliance and hypoxemia.","contentResultats":"Four hundred forty-three patients with severe COVID pneumonia were admitted to our ICU during the inclusion period. One hundred eighty-seven patients were mechanically ventilated for more than ten days. Nineteen patients (10%) hadpersistent ARDS and received high-dose methylprednisolone as rescue therapy. Mean age was 68.2 + 6.3 years, median SOFA score at initiation of corticotherapy was 8. Mean delay between intubation and Methyprednisolone initiation was 19.1+5.6 days. Ten patients (53.7%) survived and were discharged from ICU, and all were still alive at day 90. Lung compliance upon initiation of corticotherapy was similar in patients who survived and those who died (20.1+12.5 and 19.9+5.6 ml/cmH2O respectively). PaO2/FiO2 ratio was also similar between both groups (152+42.6 and 124.2+31.7 respectively). Survivors showed significant improvement in both lung compliance (p=0.0324, figure1A) and PaO2/FiO2 ratio (p=0.0352, figure 1B).","contentDiscussion":"","contentConclusion":"In this cohort of persistent COVID-ARDS patients with suspicion of PFP evolution, both lung compliance and PaO2/FiO2 ratio did significantly ameliorate in patients who survived. Whether this observed improvement in lung mechanics and hypoxemia is due to the late use of steroids, or not, has to be confirmed.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SIBLANI Dima"},{"id":99502,"num":"A34688IA","reference":"FC-168","title":"Comparison between different doses of dexamethasone and its outcome on critically ill COVID-19 patients","formatedAuthors":"Ilef ALILA (1), Amina HADDED (1), Salma JERBI (1), Sana KHARRAT (1), Rihab BOUBTANE (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) hopital Habib Bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"The coronavirus disease 2019 significantly impacted human society. Recently, the synthetic pure glucocorticoid dexamethasone was identified as an effective compound for treatment of severe COVID-19. (1) The aim of this study was to compare the different doses of dexamethasone prescribed and their impact on prediction of outcome in critically ill COVID-19 patients.","contentPatientsMethods":"We conducted a retrospective study in a medical ICU over a period of 16 months [September 2020-December 2021] including patients with SARS-COV2 infection. Dexamethasone-based corticosteroid therapy was introduced from day one in patients with acute distress respiratory syndrom (ARDS) with different doses: ≤8mg/day, 12mg/day and 24mg/day.","contentResultats":"During the study period, 430 patients were included with a mean age of 58.7 ± 15.9 and a gender ratio of 1.5. The median SAPSII and SOFA score were respectively of 28 ± 15 and 4 ± 2.6. Most patients had comorbidities, including hypertension (35.8 %), obesity (31.6%) and diabetes (36.7%).\n At admission, 301 patients had severe ARDS (70%). Dexamethasone was prescribed with 12mg/day in 342 patients (79.5%), with ≤8mg/day in 51 patients (11.9%) and 24mg/day in 37 patients (8.6%).The use of invasive mechanical ventilation was more frequent in patients who received 12mg/day (46%; p=0.035). The occurrence of infection during hospitalization was high in the same group of patients (46%; p=0.014). There was no significant difference between the three doses of dexamethasone in terms of diabetic decompensation, hypokalemia or mortality (Table I).","contentDiscussion":"","contentConclusion":"This study showed that the use of different doses of dexamethasone was not associated with different outcome in critically ill COVID-19 patients admitted in ICU.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1211","session":"FLASH COM - Immunomodulation dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1)Tomoshige Kino, Irina Burd, James H. Segars : Dexamethasone for Severe COVID-19: How Does It Work at Cellular and Molecular Levels?","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALILA Ilef"},{"id":99503,"num":"A34398KS","reference":"FC-169","title":"Delirium in critically ill patients: A prospective study","formatedAuthors":"Khedher SANA (1), Majid Al Dossari HASSAN (1)
(1) AFH Wady addawassir, Riadh, ARABIE SAOUDITE","contentIntroduction":"Delirium is among the most common problem in the intensive care unit (ICU). It is often under diagnosed and it has a considerable impact on morbidity and mortality rate. We aimed to determine the incidence, risk factors and outcomes of delirium in the ICU.","contentPatientsMethods":"We conducted a retrospective study including ill patients fulfilling the criteria for admission to ICU unit between January 2022 to September 2022. Delirium was assessed during each shift (morning and evening), by trained nurses, using the Confusion Assessment Method for the ICU (CAM-ICU). SOFA and RASS scores was calculated on admission. Demographics and clinical status were also collected based on the medical record.","contentResultats":"One hundred twenty (120) patients were included. Median age was 75±13 years with a sex ratio of 1.2. Fourteen (42) developed delirium (incidence: 35%); 20% were hypoactive, 5%mixed and 10 %were hyperactive in type. They are older (70 versus 55) and had a significantly higher SOFA score at admission (8[8–10] versus 3 [2–4], p<0.001), RASS (2.8 versus 1.3, p <0.001). Cumulative doses of Midazolam (80mg versus 48mg, p<0.001). The presence of visual or auditory deficits were reported at baseline in 27.7% of patients with delirium. They had also longer ICU length-of-stays (6 vs 14, p <0.001) and mortality was significantly higher in the delirium group (44.4% versus 28%).","contentDiscussion":"","contentConclusion":"The incidence of delirium in our ICU is 35 %, it was associated with a 2-fold increase in the risk of death and prolongs the length of hospitalization. Our results were an opportunity to implement a strategy for assessement and surveillance and prevention of delirium to improve the care in ICU.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SANA Khedher"},{"id":99504,"num":"A34711sb","reference":"FC-170","title":"Mortality predictors of snake bite envenomation in southern Tunisia","formatedAuthors":"Sabrine BRADAI (1), Rezk GHORBEL (1), Olfa TURKI (1), Kamilia CHTARA (1), Mabrouk BAHLOUL (1), Chokri BEN HAMIDA (1), Mounir BOUAZIZ (1)
(1) Habib Bourguiba university hospital, Sfax, Tunisia, Sfax, TUNISIE","contentIntroduction":"Snakebite envenoming is a neglected tropical disease that kills more than 100.000 people every year. In Tunisia, it is particularly frequent in the sub-Saharan regions with high mortality and morbidity. Therefore, we aim to identify the predictor factors of mortality in snakebite envenomation in our region.","contentPatientsMethods":"It is a retrospective descriptive study, conducted at the intensive care unit (ICU) of Habib Bourguiba university hospital, Sfax, Tunisia, over a period of 16 years (from January 01, 2006, to December 31, 2021). Snakebite envenomation was defined by a history of snakebite. Survivor and nonsurvivor subgroups were compared to identify predictors of mortality.","contentResultats":"Out of the 19 included patients, 4 patients died. The mortality rate was 21.1%. Univariate analysis revealed that at ICU admission : high SOFA (p=0.017), high shock index (p=0.024), high value of leucocytes (p=0.001), high value of blood urea (p=0.003) and the presence of clinical signs of shock (p=0.037), are associated with mortality.","contentDiscussion":"","contentConclusion":"Early evaluation of severity at admission is crucial in the management of snakebite envenomation. Further multicentric studies are required to approve a severity scale proper to snakebite envenomation in Tunisia.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"World Health Organization. Venomous snakes distribution and species risk categories. 2017. [Online] Available from: https://apps.who.int/ bloodproducts/snakeantivenoms/database/default.html.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Chakroun-Walha O, Issaoui F, Nasri A, Bradai H, Farroukh A, Karray R, et al. Early severity predictors of snakebite envenomation in the southern region of Tunisia: a multivariate analysis. J Acute Dis. 2021;10(2):71.","presentateur":"GHORBEL Rezk"},{"id":99505,"num":"A34411AM","reference":"FC-171","title":"Acquired agitation in ARDS with Covid-19 compared to influenza patients: a propensity score matching observational study.","formatedAuthors":"Adel MAAMAR (1), Clémence LIARD (1), Florian REIZINE (1), Benoit PAINVIN (1), Flora DELAMAIRE (1), Valentin COIRIER (1), Quentin QUELVEN (1), Pauline GUILLOT (1), Mathieu LESOUHAITIER (1), Jean-Mac TADIÉ (1), Arnaud GACOUIN (1)
(1) CHU de Rennes, Hôpital Pontchaillou, Rennes, FRANCE","contentIntroduction":"A growing body of evidence reports that agitation and encephalopathy are frequent in critically ill Covid-19 patients. Our aim was to assess the incidence and risk factors of agitation in critically ill ARDS patients with Covid-19, and compare these findings to a population of patients with ARDS patients with influenza.","contentPatientsMethods":"We included all the patients with laboratory-confirmed Covid-19 infection and ARDS admitted to our medical intensive care unit (ICU) between March 10th, 2020 and April 16th, 2021, and all the patients with laboratory-confirmed influenza infection and mechanical ventilation (MV) admitted to our ICU between April 10th, 2006 and February 8th, 2020. Clinical data, biological data and were retrospectively collected. We also recorded previously known factors associated with agitation (ICU length of stay, length of invasive ventilation, SOFA score and SAPS II at admission, sedative and opioids consumption, time to defecation). Agitation was defined as a day with Richmond Agitation Sedation Scale greater than 0 after exclusion of other causes of delirium and pain. We compared the prevalence of agitation among Covid-19 patients during their ICU stay and in those with influenza patients. To improve the balance of baseline characteristics and reduce the effects of selection bias and potential confounding factors in this observational study, a propensity score analysis was performed. Second, we used a Cox-proportional hazard model to determine whether agitation during the ICU stay was independently associated with mortality at day-28.","contentResultats":"We included 241 patients (median age 62 years [53-70], 158 males (65.5%)), including 146 patients with Covid-19 and 95 patients with Influenza. One hundred eleven (46.1%) patients had agitation during their ICU stay. Patients with Covid-19 had significantly more agitation than patients with influenza (respectively 80 patients (54.8%) and 31 patients (32.6%), p < 0.01). After matching with a propensity score, Covid-19 patients remained more agitated than influenza patients (49 (51.6% vs 32 (33.7%), p = 0.006). Agitation remained independently associated with mortality after adjustment for other factors (HR = 1.85, 95% CI 1.37-2.49, p < 0.001).","contentDiscussion":"","contentConclusion":"Agitation in ARDS Covid-19 patients is more frequent than in ARDS influenza patients. The agitation was not associated with common risk factors, such as severity of illness or sedation. These findings suggest that SARS-CoV-2 is directly and indirectly involved in agitation and should probably be acknowledged as a risk factor. As agitation can be one of the presentations of a delirium, its presence should alert us to the risk of encephalopathy.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MAAMAR Adel"},{"id":99506,"num":"A34600FE","reference":"FC-172","title":"Neuro-psychiatric complications of COVID-19 in intensive care unit","formatedAuthors":"Fatma ESSAFI (1,2), Nour Zayneb JAAFAR (1,2), Malek KHARRAT (1,2), Khaoula BEN ISMAIL (1,2), Imen TALIK (1,2), Moez KADDOUR (1,2), Takoua MERHABENE (1,2)
(1) Intensive care unit, Regional Zaghouan’s Hospital, Zaghouan, TUNISIE ; (2) Faculty of medicine of Tunis, Tunis El-Manar university, Tunis, TUNISIE","contentIntroduction":"Several studies have reported association between COVID-19 infection and a plethory of neuropsychiatric complications whereas the neuropsychiatric damage is still contested.\n We aimed to describe the epidemiology of neuropsychiatric manifestations in patients hospitalized for confirmed severe COVID-19 pneumonia and determine its impact on patient’s management and outcome.","contentPatientsMethods":"All data of confirmed COVID-19 patients hospitalized in Zaghouan’s Hospital ICU between March 2020 and January 2022 were retrospectively analyzed. Were collected epidemiological, clinical, prescribed medications and outcomes. Factors associated with neuropsychiatric complications and its impact on mortality were evaluated through binary logistic regression models, by comparing two groups: patients with or without neuropsychiatric manifestations.","contentResultats":"Of the total of 365 patients included, 201 have developed neurologic and/or psychiatric manifestations during their hospital stay (55%). Median age was 58 [17-89] with sex ratio 1.3. Median SAPS II and APPACHE II scores were 26±8.3 and 7±4.9 respectively. Fifteen patients have underlying psychiatric disease history and two have a history of ischemic stroke without sequelae.\n Neurologic disorders were described in 125 patients. It consisted on 118 episodes of headache, 6 ischemic stroke and 2 case of encephalitis, one of which was symptomatic of status epilepticus; no peripheral nervous system involvement was reported. \n Psychiatric disturbance was seen in 121 patients. The most common manifestations were: an unexpected agitation in 79 patients, sleep disturbances in 25 patients, depressed mood in 20 patients, anxiety in 8 patients, delirium in 3 cases and confusion in 2 cases. Depression was manifested by reduced appetite and anorexia, tiredness and lack of energy and irritability.\n Management of patients consisted in majority of cases in long-acting benzodiazepine prescription alone or associated to neuroleptic agents.\n No differences were noted in demographic characteristics between patients who developed neuropsychiatric signs and the others. But active smoking was associated with the presence of neuropsychiatric signs (44.7% vs 31.7%, p=0.034). At admission, the 2 groups had comparable respiratory exchange and laboratory findings. Presence of psychiatric signs was significantly associated with more use of invasive mechanical ventilation (49%vs24.3%, p<103), longer length of ICU stay (11 vs 7 days,p<10-3) and higher ICU mortality (60% vs 33%, p<10-3). Headacke, the most common neurologic manifestation, alone was not associated with worse prognosis.","contentDiscussion":"","contentConclusion":"Neuroinflammation associated to SARS-CoV-2 infection could be responsable for a wide and still unknown spectrum of neuropsychiatric disorders which are associated with poor prognosis and high mortality. Long term follow up is recommended to detect disability consequences of neuro-COVID.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"JAAFAR Nour Zayneb"},{"id":99507,"num":"A34402TT","reference":"FC-173","title":"Incidence and severity of the post-intensive care syndrome at 1 year after a long hospitalization in ICU for a COVID-19-related ARDS","formatedAuthors":"Tona TCHOUBOU (1), Tristan MORICHAU-BEAUCHANT (2), Mélanie SAINT-JOUAN (2), Fabrice DAVIAUD (2), Jerôme FICHET (2), Stéphane THIERRY (2), Julien NAHUM (2), Jean-Michel MAILLET (2)
(1) Hôpital Delafontaine, Saint-Denis, FRANCE ; (2) Centre Cardiologique du Nord, Saint-Denis, FRANCE","contentIntroduction":"Postintensive Care Syndrom (PICS) is a frequent condition in ICU-survivors including physical, cognitive and psychological disorders. The long-term consequences of an hospitalization in intensive care for severe COVID-19 are unknown. \n The aim of this study was to assess the incidence and severity of cognitive and psychological disorders, the sequelae of hospitalization and their impact on the health-related quality of life of patients who survived at one year after a prolonged hospitalization in intensive care for COVID-19-related ARDS.","contentPatientsMethods":"Prospective, descriptive, monocentric cohort study, carried out in the Seine-Saint-Denis department in France between May and July 2021. Patients who received mechanical ventilation of at least 72 hours during a stay in intensive care of at least 7 days for COVID-19-related ARDS were included.","contentResultats":"Thirty out of thirty-six eligible patients were assessed at a median time of 423 days since infection (IQR [404 – 437]). The patients' quality of life was impaired mainly in the physical domain. Sixteen percent of patients complained of asthenia and 23% reported muscle weakness. Fifty-three percent of patients complained of cognitive impairment and 36% of patients had symptoms of post-traumatic stress disorder. Symptoms of anxiety were found in 40% and symptoms of depression in 16% of patients. Seventy percent of patients had at least one skin, neurological or joint sequelae of hospitalization. Twelve patients (40%) had persistent dyspnea.","contentDiscussion":"This study has several limitations. It is descriptive, monocentric and the study population is quite small. Yet, to this day, the datas concerning the sequelae of severe COVID-19 especially in the critically ill remain scarces. Since the \"first wave\" of the pandemics, the management of COVID-19 ARDS changed and effective vaccines have been found. Further studies are mandatory to assess the effect of these findings on the prevalence and severity of the PICS.","contentConclusion":"The sequelae of an hospitalization in intensive care for a COVID-19-related ARDS are common and impair survivors' health-related quality of life at one year after infection. This study among others will help to know better the long-term consequences of the COVID-19 pandemics in terms of PICS.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TCHOUBOU Tona"},{"id":99508,"num":"A34583DZ","reference":"FC-174","title":"Management of hemorrhagic stroke in neuroreanimation","formatedAuthors":"Dalila ZEGHDOUD (1), Dalila BOUGDAL (1), Souhila SADAT (1)
(1) EHS SALIM ZEMIRLI EL HARRACH , ALGER, ALGÉRIE, Alger, ALGERIE","contentIntroduction":"Hemorrhagic strokes represent 10 to 15% of all strokes. The incidence increases with age, especially beyond 55 years. The AVCH is a serious pathology whose mortality is between 30 to 60% at 30 days. Half of the deaths occur within the first\n 48 hours. The management of AVCH in neuroresuscitation units has reduced this morbidity and mortality.\n The objective of our study is to study the impact of the management of hemorrhagic stroke in a neuroresuscitation unit.","contentPatientsMethods":"This is a prospective, monocentric study from January 2010 to October 2019. The study involved patients admitted for hemorrhagic stroke, confirmed by brain CT. Patients with traumatic brain hematomas, hemorrhagic changes in ischemic stroke, and cerebro-meningeal hemorrhage were excluded from the study. Demographic data, history, Glasgow score, CT data, initial medical care and short-term change were studied. The surgical indication was at the discretion of the surgeon","contentResultats":"During the study period 120 patients with an average age of 60 years were included, with a sex ratio of 1.1. 55% of patients were hypertensive, 13% diabetic, of which 14% were on AVK and 26% on platelet antiaggressors. No risk factors were found in 32% of patients. The average Glasgow admission score was 08/15. At imaging, 60% had a deep localization of the hematoma and 54% a hydrocephalus. Medical management was based on monitoring of blood pressure figures in 58%, the use of mechanical ventilation in all patients, osmotherapy in 22% and reversion of anticoagulant therapy in 6% of cases. Surgery was indicated in 60% of cases: An external ventricular shunt in 70% of cases and a decompression and evacuation of the cerebral hematoma in 40% of cases. Overall mortality was 70%.","contentDiscussion":"","contentConclusion":"In terms of public health, stroke is a medical, social and economic scourge. It has serious life-threatening and functional consequences: just under 75% of people with CHD die within a year, and more than half of stroke survivors have significant consequences","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ZEGHDOUD Dalila"},{"id":99509,"num":"A34676hb","reference":"FC-175","title":"Scorpion envenomation in the emergency department: a prospective study of predictive factors of severity","formatedAuthors":"Rim KARRAY (1), Mariem MALLEK (1), Hana BEN ALI (1), Ala ZOUARI (1), Imen BEN SALEM (1), Rizk GORBEL (1), Olfa CHAKROUN-WALHA (1), Noureddine REKIK (1)
(1) CHU Habib Bourguiba Sfax Tunisie, Sfax, TUNISIE","contentIntroduction":"Scorpion envenomation is common in the tropical and subtropical regions. It poses a major public health problem with some patients having serious clinical manifestations and severe complications including death.\n The aim of our study was to describe the predictive factors of severity in the management of scorpion envenomation patients admitted in the acute care unit.","contentPatientsMethods":"A 6 months prospective analytic observational single-center study including patients admitted for stage II or III of scorpion envenomation. Stage I scorpion envenomation were excluded. Statistical analysis was performed using the statistic software SPSS 20.","contentResultats":"Sixty-six patients were included. Mean age was 29±20 years [1 to 84 years old] with female predominance (sex-ratio=0.8). the majority of patients (90%) were staged II according to severity.\n Among demographic factors, age (p=0.007) and the mode of transport in the acute care unit (p=0.001) were predictor factor of mortality. However, comorbidities and gender had no prognostic impact.\n Clinical predictor factor of mortality on admission were: agitation (p<0.001), dyspnea (p=0.02), abdominal pain (p=0.03), Rapid breathing (p=0.01), oxygen saturation (p=0.04), priapism (p= 0.01) and the presence of signs of shock (p<0.001): marbling, cool skin.\n Leukocyte, glucose levels and troponin level increased significantly with the severity of envenomation and are correlated with high mortality: p respectively 0,001. Asidosis (p= 0.026), hypoxemie (p= 0,04) and anemie (p= 0,008) were also predictive factor of mortality\n The presence of abnormalities on electrocardiogram (p=0.005), chest X-ray (p= 0.03) and cardiac ultrasound (p<0.001) were associated with higher mortality.\n Finally, a significant association was found between the cardiogenic shock requiring the use of dobutamine and death rate(p<0.001).","contentDiscussion":"","contentConclusion":"Scorpion envenomation is an accidental pathology that continues to be serious in our country specially in summer. The predictive factors of mortality seem similar to those described in the literature. However, new diagnostic tools may be helpful in the early detection of patients with significant risk of death.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BEN ALI Hana"},{"id":99510,"num":"A34388JP","reference":"FC-176","title":"Impact of intensive physical therapy on patients with neuromyopathy in a weaning unit after prolonged stay in ICU","formatedAuthors":"Jean-Baptiste PERETOUT (1), Josépine COTTIAS (1), Camille FRANTZ (1), Amaury DUARTE (1), Carlos DIAZ-LOPEZ (1), Gérald CHOUKROUN (1)
(1) Hôpital Forcilles - Fondation Cognacq-Jay, Férolles-Attilly, FRANCE","contentIntroduction":"Neuromyopathy is a severe but common complication in ICU, particularly for patients with prolonged stays1. Intensive physical therapy with a muscle strengthening program and a daily schedule allows a faster recovery. The objective of this study is to determine the impact of intensive physical therapy on the functional recovery of these patients in a weaning unit.","contentPatientsMethods":"This is a retrospective, descriptive study in a respiratory weaning unit over the year 2021. All patients hospitalized in the weaning unit were included. The MRC score at admission was used to determine the diagnosis and severity of neuromyopathy and was compared with the same score at discharge. The prevalence of neuromyopathy at admission was also investigated. Demographic and physical therapy characteristics were collected. All inpatients with complete data were analyzed.","contentResultats":"In 2021, 144 patients were admitted. A total of 134 patients were analyzed with male 70%, age 63 ± 12 years, COVID 70%.\n The MRC score was statistically higher at discharge than at admission : 52,3 ± 11,4 vs 39,5 ± 14 (p<0,001). The prevalence of neuromyopathy at admission was 73% (n=98).\n During the hospitalization, delivered rehabilitation treatment were: sitting on the edge of the bed in 93% , reverticalization in 82% and walking in 57%.\n The different techniques are presented in Table I.","contentDiscussion":"","contentConclusion":"Intensive physical therapy is associated with an improvement in the MRC score for patients during their stay in the weaning unit. Multidisciplinary management also contributes to improving the different functional aspects of the patients.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1212","session":"FLASH COM - Complications neuro en réanimation","theme":"Neurologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"De Jonghe B, Lacherade JC, Durand MC, Sharshar T. Critical illness neuromuscular syndromes. Crit Care Clin. 2007 Jan;23(1):55-69","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PERETOUT Jean-Baptiste"},{"id":99511,"num":"A34667CV","reference":"FC-177","title":"Breast cancer in the ICU: outcomes and prognosis factors","formatedAuthors":"Clara VIGNERON (1), Julien CHARPENTIER (1), Florence COUSSY (2), Jérôme ALEXANDRE (1), Frédéric PÈNE (1), Matthieu JAMME (3)
(1) Hôpital Cochin, Paris, FRANCE ; (2) Institut Curie, Paris, FRANCE ; (3) Hôpital Privé de l’ouest Parisien, Ramsay Générale de Santé, Trappes, FRANCE","contentIntroduction":"Breast cancer has surpassed lung cancer as the most frequently diagnosed cancer with an estimated 2.3 million new cases in 2020. One in eight to ten women will have breast cancer during their lifetime. Compared with other solid cancers, its prognosis is usually seen as encouraging even at a metastatic stage. Surprisingly, characteristics of breast cancer patients hospitalized in the ICU have seldom been described and especially whether this common pathology affects admission patterns and prognosis in critically-ill patients.","contentPatientsMethods":"We conducted a retrospective monocenter study including patients with breast cancer requiring unplanned admission to a medical ICU over a 14-year period (2007-2020). Non-inclusion criteria were the following: admission to secure a procedure, planned admissions following elective surgery and patients with cancer cured for more than 5 years. Independent predictors of in-ICU and one-year outcome (available for n=170 (96%) patients) were addressed by a cause-specific multivariate Cox regression analysis.","contentResultats":"One hundred seventy seven patients (median age=65 [57-75] years) were analysed. Breast cancer was at a metastatic stage for 122 (68.9%) patients and recently diagnosed or in progression under treatment in respectively 25 (14.1%) and 76 (42.9%) patients. Median SOFA score at admission was 5 [4-8] and patients required invasive mechanical ventilation, vasopressors/inotropic agents and renal replacement therapy in respectively 72 (40.7%), 57 (32.2%) and 26 (14.7%) cases. Admissions were related to sepsis in 56 (31.6%) patients, to iatrogenic/procedural complication in 19 (10.7%) patients and to specific (i.e. directly linked to the underlying malignant disease) complication in 47 (26.6%) patients. ICU, hospital and one-year mortality rates were respectively 20.9%, 30.5% and 57.1%.\n In multivariate analysis, factors associated with ICU-mortality were invasive mechanical ventilation (Cause specific hazard (CSH) 2.53 [1.11-5.75], p=0.03) and poor performance status (at 3 or 4) (CSH 2.37 [1.18-4.80], p=0.02). One-year mortality in ICU-survivors was independently associated with the occurrence of specific complications during ICU stay (CSH 2.20 [1.31-3.71], p=0.003), a triple negative cancer status (CSH 1.97 [1.06-3.67], p=0.03) and poor performance status (CSH 1.51 [1.19-1.92], p<0.001).","contentDiscussion":"","contentConclusion":"One in four breast cancer patients are admitted to the ICU for life-threatening specific complications directly linked to their underlying malignant disease. The in-ICU prognosis is encouraging and not related to oncologic characteristics supporting broad-admission policy in this population. Long-term prognosis is poor, especially for those patients with advanced malignancy.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"VIGNERON Clara"},{"id":99512,"num":"A34535SB","reference":"FC-178","title":"Outcome of patients with solid tumors considered for ICU admission: a single-center experience","formatedAuthors":"Soraya BENGUERFI (1), Baptiste HIRSINGER (1), Colin De Verdière VALENTINE (1), Judith RAIMBOURG (2,3), Hélène SENELLART (2), Caroline VIALA (4), Amélie SEGUIN (1), Paul DECAMPS (1), Luc DESMEDT (1), Jean REIGNIER (1), Emmanuel CANET (1)
(1) Médecine Intensive Réanimation, CHU de Nantes, Nantes, FRANCE ; (2) Département d'Oncologie médicale, Institut de cancérologie de l'Ouest, Saint-Herblain, FRANCE ; (3) Nantes Université, INSERM, CNRS, Université d’Angers, CRCI2NA, Nantes, FRANCE ; (4) Service d'Oncologie médicale, CHU de Nantes, Nantes, FRANCE","contentIntroduction":"Patients with solid tumors are increasingly considered for ICU admission. Our purpose was to evaluate the outcome of patients with solid tumors considered for ICU admission and to assess the performance of physiological scores at the time of triage for predicting hospital mortality.","contentPatientsMethods":"Prospective cohort study including all patients with solid tumors for whom ICU admission was requested between July 2019 and December 2021 in a French University-affiliated Hospital.","contentResultats":"Of the 6,262 patients considered for ICU admission, 410 patients (6.5%) had solid tumors. Median age was 64 and 137 patients (33.4%) were women. At the time of triage, 206 patients (50.8%) had sepsis. Of the 410 patients evaluated, 176 patients (42.9%) were ultimately admitted. Diagnoses of hemoptysis (odds ratio 10.35; 95% CI 2.80-66.89; p 0.006) and pneumothorax (odds ratio 17.94; 95% CI 3.48-328.64; p 0.002) were independently associated with ICU admission, whereas older age (odds ratio 0.98, 95% CI 0.96-0.99; p 0.004) was independently associated with ICU refusal. Of the 234 patients (57.1%) who were denied ICU admission, 61 patients (26.1%) were deemed too well to benefit from ICU, and 173 (73.9%) were deemed too sick to benefit from ICU. ICU and 6-months survival rates of patients admitted to the ICU were 80.1% and 58.0%, respectively. In patients not admitted in ICU because considered too well, hospital survival was 86.9% and overall survival at 6 months was 67.2%. In patients not admitted in ICU because considered too sick, hospital survival was 37.0% and overall survival at 6 months was 19.7%. qSOFA, NEWS score and Shock index at the time of triage were similar between patients admitted and not admitted to the ICU and demonstrated poor performances for predicting hospital mortality (AUC 0.52, 0.62 and 0.51, respectively).","contentDiscussion":"","contentConclusion":"In our experience, patients with solid tumors had a high rate of treatment limitations taken at the time of triage. Hospital survival of patients admitted to the ICU was encouraging. However, both the significant rates of hospital mortality in patients considered too well to benefit from ICU admission, and the survival rates of patients considered too sick underline the limits of clinical judgment at the time of triage. Unfortunately, physiological scores at the time of triage demonstrated poor performances for predicting hospital mortality.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BENGUERFI Soraya"},{"id":99513,"num":"A34530BP","reference":"FC-179","title":"Mechanisms, management and prognosis of severe gastrointestinal hemorrhage in patients with pancreatic cancer: a retrospective multicenter study.","formatedAuthors":"Benjamin PICARD (1), Emmanuel WEISS (2,3), Olivier CALIEZ (4), Antoine GOURY (5), Vincent BONNY (6), Gabriel KEMOUN (1), Marika RUDLER (4,7), Rami RHAIEM (8), Jean Baptiste BACHET (4,7), Maxime RONOT (3,9), Julien MAYAUX (1), Alexandre DEMOULE (1,10), Maxens DECAVÈLE (1,10)
(1) AP-HP.Sorbonne Université - Service de Médecine Intensive et Réanimation - Département R3S - Hôpital de la Pitié Salpêtrière, Paris, FRANCE ; (2) AP-HP.Nord - Université de Paris - Département d’Anesthésie-Réanimation - Hôpital Beaujon, Clichy, FRANCE ; (3) Université de Paris - UMRS1149 - Centre de recherche sur l’inflammation, Paris, FRANCE ; (4) AP-HP.Sorbonne Université - Service d’Hépato-Gastro-Entérologie - Hôpital de la Pitié Salpêtrière, Paris, FRANCE ; (5) CHU de Reims - Unité de Médecine Intensive et Réanimation Polyvalente - Hôpital Robert Debré, Reims, FRANCE ; (6) APHP-6 Sorbonne Université - Service de Médecine Intensive et Réanimation - Hôpital Saint-Antoine, , Paris, FRANCE ; (7) Sorbonne Université - INSERM Centre de Recherche Saint-Antoine (CRSA) - Institute of Cardiometabolism and Nutrition (ICAN), Paris, FRANCE ; (8) CHU de Reims - Service de Chirurgie hépatobiliaire, pancréatique et oncologique digestive - Hôpital Robert Debré, Reims, FRANCE ; (9) AP-HP.Nord - Université de Paris - Département de Radiologie - Hôpital Beaujon, Clichy, FRANCE ; (10) Sorbonne Université - INSERM UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, FRANCE","contentIntroduction":"Gastrointestinal bleeding (GIB) is a frequent and potentially life-threatening complication in patients with pancreatic cancer. Although GIB represents the second reason for intensive care unit (ICU) admission in pancreatic cancer patients, only limited data are available regarding bleeding mechanisms, management and outcomes in these patients. Primary aim was to identify factors associated with a successful hemostatic intervention (i.e. gastrointestinal endoscopy and/or arterial embolization). Secondary aim was to identify factors associated with ICU mortality.","contentPatientsMethods":"Retrospective multicenter cohort study in five French ICU. All consecutive patients with pancreatic cancer, admitted to the ICU for GIB between January 2009 and January 2020 were screened for inclusion. Patients with a recent pancreatic surgery (< 4 weeks) were excluded.","contentResultats":"Seventy-eight patients were included (48 (62%) males, 67 [56–73] median [interquartile interval] years-old). Tumors were mainly adenocarcinoma (91%) in cephalic position (74%). Prior to ICU admission, 81% of patients received chemotherapy and 31% underwent pancreatic resection surgery. Cancer progression was identified in 51% of cases.\n GIB mechanisms were gastroduodenal tumor infiltration (35%), gastroesophageal varices (21%) mostly related to left-sided portal hypertension, arterial aneurysm (14%), non-tumoral ulcer (11%) and miscellaneous (19%). Arterial aneurysms were more frequently detected in patients who underwent pancreatic resection (41%) than their counterpart (2%), p<0.001. During the ICU stay, 41 (53%) patients presented hemorrhagic shock, 60 (77%) received red blood cells transfusion (median number of red blood cells units 3 [2–5]), and 32 (41%) required mechanical ventilation. Sixty-two (80%) patients and 21 (27%) patients had at least one upper endoscopy and one arterial embolization, respectively.\n A successful hemostasis was achieved in 35 (45%) patients. By multivariate analysis, three independent variables were significantly associated with hemostatic interventions success: aneurysmal bleeding OR 32.76, p=0.005; ongoing chemotherapy at ICU admission OR 0.13, p=0.013 and prothrombin time ratio (PT) OR 1.05, p=0.003.\n ICU mortality rate was 20%. By multivariate analysis, four independent variables were significantly associated with ICU mortality: performance status > 2 odds ratio (OR) 9.29, p=0.045; need for mechanical ventilation OR 24.74, p=0.006; success of therapeutic interventions OR 0.07, p=0.020 and hemorrhagic shock OR 22.02, p=0.011.","contentDiscussion":"","contentConclusion":"In patients with pancreatic cancer and GIB, the success of hemostatic interventions and thus ICU mortality is influenced by the mechanism of bleeding and the PT. Early identification of arterial aneurysm (abdominal CT-scan before endoscopy), especially in patients with previous pancreatic resection surgery history, and prompt PT correction should be proposed.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PICARD Benjamin"},{"id":99514,"num":"A34375GK","reference":"FC-180","title":"Clinical features and outcomes of patients with pancreatic cancer requiring medical ICU admission: a retrospective multicenter study","formatedAuthors":"Gabriel KEMOUN (1), Emmanuel WEISS (2,4), Lina EL HOUARI (1), Olivier CALIEZ (1), Antoine GOURY (3), Vincent BONNY (6), Benjamin PICARD (1), Marika RUDLER (1,5), Rami RHAIEM (3), Vinciane REBOURS (2,4), Julien MAYAUX (1), Lisa BELIN (1), Alexandre DEMOULE (1,5), Maxens DECAVÈLE (1,5)
(1) APHP Sorbonne Université, site Pitié-Salpêtrière, Paris, FRANCE ; (2) APHP-Nord, Université de Paris, Hôpital Beaujon, Clichy, FRANCE ; (3) Hôpital Robert Debré, CHU de Reims, Reims, FRANCE ; (4) Université de Paris, Paris, FRANCE ; (5) Sorbonne Université, Paris, FRANCE ; (6) APHP-6 Sorbonne Université, site Saint-Antoine, Paris, FRANCE","contentIntroduction":"Pancreatic cancer is the sixth leading cause of solid malignancy in France, with increasing incidence and low survival probability. About 5-10% of cancer patients will require intensive care unit (ICU) admission in the two-year following diagnosis. However, there is no data regarding clinical features and outcomes of pancreatic cancer patients admitted to the ICU. Primary aim was to describe the reasons for ICU admission. Secondary aim was to identify factors associated with ICU mortality.","contentPatientsMethods":"Retrospective multicenter cohort study in five french ICUs from January 2009 to January 2020. All consecutive patients with proved pancreatic cancer admitted to the ICU were screened for inclusion. Patients with a recent surgery were excluded (< 4 weeks). Logistic regression multivariate analysis was performed on ICU mortality.","contentResultats":"Two hundred and sixty-nine patients were included (161 (60%) males, 65 [57−73] median [interquartile interval] years old, simplified acute physiology score 2 (SAPS 2) 39 [29–55]). Tumors were mainly adenocarcinoma (90%) in cephalic location (70%). Time between diagnosis and ICU admission was 8 [1–17] months. At ICU admission, most of the cancer were metastatic (57%) and the disease was responsive/stable, newly diagnosed or progressive in 32%, 25% and 43% of cases respectively. Prior to ICU admissions 74% of patients received chemotherapy, 24% surgery and 13% radiotherapy.\n By frequencies, reasons for ICU admission were sepsis/septic shock (32%) followed by gastrointestinal bleeding (28%), acute respiratory failure (16%), metabolic disorder (12%) and miscellaneous (12%). Among the 87 patients admitted with sepsis/septic shock, a biliary tract infection was identified in 45 (52%) patients. Biliary tract infection was more frequently observed in tumors with cephalic location than their counterparts (61% vs. 24%, p=0.003). During the ICU stay, mechanical ventilation and vasopressors were required in 101 (38%) and 95 (35%) patients.\n ICU mortality rate was 26% 95% confidence interval [20%; 31%]. Using multivariate analysis, performance status 3-4 (OR 3.58), cancer status (responsive/stable -ref-, newly diagnosed OR 3.28, progressive OR 5.99), mechanical ventilation (OR 8.03), vasopressors (OR 4.19), SAPS 2 (OR 1.69) and pH (OR 0.02) were independently associated with ICU mortality.","contentDiscussion":"","contentConclusion":"The reasons for ICU admissions of pancreatic cancer patients seem to substantially differ from that observed in previous work on solid cancer (acute respiratory failure). ICU mortality seems roughly similar to that observed also in previous works on solid cancer and is strongly influenced by performance status, disease status and organs failure at ICU admission.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"KEMOUN Gabriel"},{"id":99515,"num":"A34351WM","reference":"FC-181","title":"Quality of life of cancer patients at 3 months after ICU stay : a prospective case-control study","formatedAuthors":"Anne Claire TOFFART (1), Wassila MARNAS (1), Sophie JERUSALEM (1), Alexandre GODON (1), Francois BETTEGA (1), Gael ROTH (1), Julien PAVILLET (1), Edouard GIRARD (1), Louis Marie GALERNEAU (1), Carole SCHWEBEL (1), Jean Francois PAYEN (1)
(1) CHU GRENOBLE, La Tronche, FRANCE","contentIntroduction":"Although short- and long-term survival in critically ill cancer patients was extensively studied, only limited data exist concerning their quality of life (QoL) following an intensive care unit (ICU) stay. We thus sought to determine the impact of an ICU stay on QoL at 3 months in solid cancer patients.","contentPatientsMethods":"A prospective observational case-control study was conducted between February 2020 and February 2021 involving three French ICUs. Surviving ICU patients with lung, colorectal, or head and neck cancers at 3 months after ICU discharge were matched with non-ICU cancer patients in terms of their cancer type, anticancer treatment goal (curative/palliative), and treatment line. QoL was assessed using the Short Form 36 (SF-36) health survey (ranging 0-100, higher values indicating better QoL) including mental (MCS) and physical (PCS) components. Anticancer treatment at 3 months was additionally assessed.","contentResultats":"Overall, 23 surviving ICU cancer patients were matched with 46 non-ICU cancer patients. All patients answered the survey except for four pertaining to the ICU group. MCS was significantly higher in ICU patients than non-ICU patients, with a median of 54 (interquartile range [IQR]: 42-57) versus (vs.) 47 (IQR: 37-52), respectively (p = 0.01). PCS did not differ between both groups, with a median of 35 (IQR: 31-47) vs. 42 (IQR: 34-47) (p = 0.24). The multivariate analysis revealed a non-significant association between ICU/non-ICU patient status and patient quality-of-life scores (MCS or PCS) at 3 months post-discharge. The therapeutic strategy based on anticancer treatment at 3 months post-discharge was similar between both groups. A good performance status (PS) (coef. 1.46, confidence interval [CI]95%: 1.11-1.90, p = 0.01) and non-metastatic cancer status (coef. 1.21, CI95%: 1.05-1.40, p = 0.01) were independently associated with a higher PCS.","contentDiscussion":"","contentConclusion":"At 3 months, cancer patients admitted into ICU displayed comparable QoL with matched patients not admitted into ICU. Thus, the challenging issue is to identify patients with good prognostic factors who would benefit from an ICU stay in terms of QoL and continue their anticancer treatments. These results require confirmation by a multicenter study.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MARNAS Wassila"},{"id":99516,"num":"A34518CL","reference":"FC-182","title":"Clinical features and outcomes of chimeric antigen receptor T-cell patients admitted to the intensive care unit: a single center experience","formatedAuthors":"Corentin LE CACHEUX (1), Clara SORTAIS (1), Thomas GASTINNE (1), Amélie SEGUIN (1), Soraya BENGUERFI (1), Maïté LACOU-AGBAKOU (1), Gauthier BLONZ (1), Jean REIGNIER (1), Emmanuel CANET (1)
(1) CHU de Nantes, Nantes, FRANCE","contentIntroduction":"Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for refractory hematological malignancies, but can induce severe adverse events. We aimed to report the clinical features and outcomes of CAR T-cell patients admitted to the intensive care unit (ICU).","contentPatientsMethods":"We retrospectively included all adult patients admitted to a French University-affiliated ICU between August 27, 2018 and January 18, 2022, within 3 months after CAR T-cell therapy.","contentResultats":"We report 33 ICU stays for 30 patients, out of 87 (i.e., 34.5% ICU admission) treated by CAR-T cell therapy during the study period. Hematological malignancies were predominantly lymphoma (76.7%) and multiple myeloma (16.7%).\n ICU admission occurred 5 days (IQR 2.5-9.0) after CAR T-cell injection. Reasons for ICU admission were hemodynamic instability (42.4%), neurological failure (36.4%), and close monitoring (24.2%). Median SOFA and IGS2 scores were 4 (IQR 3.0-6.5) and 45 (IQR 37-50), respectively.\n All but one patients (n=29, 96.7%) met the criteria for cytokine release syndrome (CRS), of whom 5 (17.2%) developed grade 3-4 toxicity. Immune effector cell-associated neurotoxicity syndrome (ICANS) occurred in 20 (66.7%) patients, of whom 12 (60%) had grade 3-4 toxicity. ICANS was identified 4 days (IQR 2-4) after CRS, and 3 (10%) patients developed both CRS and ICANS grade 3-4 toxicities. Tocilizumab was used in 28 (93.3%) patients, with a median of 2 doses (IQR 1.0-3.0). Steroids were given in 24 (80%) patients, of whom 5 (20.8%) received high-dose pulse therapy.\n Broad-spectrum antimicrobial therapy was delivered during 32 (97%) ICU stays. Overall, 15 (50.0%) patients had a documented infection. Bacterial infections were reported in 13 (43.3%) patients and 2 (6.7%) patients had fungal infections (one pulmonary aspergillosis and one mucormycosis). Hemophagocytic syndrome was noted in 6 (20%) patients. Life-sustaining therapies were required for 12 (36.4%) patients: 11 (33.3%) received vasopressors, 7 (21.2%) were mechanically ventilated and 4 (12.1%) underwent dialysis. Overall, 3 (9.1%) patients died in the ICU (2 of them during a second ICU admission). At day-90, 11 (44.0%) patients were alive with complete remission, 5 (20%) were alive with hematological malignancy relapse, and 9 (36%) had died.","contentDiscussion":"","contentConclusion":"ICU admission is common after CAR T-cell therapy, mostly for the management of specific toxicities. Our experience is encouraging with low ICU mortality despite a high rate of grade 3-4 toxicities, and almost half of the patients being alive in complete remission at day-90. Further studies are needed to improve the treatment of such toxicities which remains largely empirical.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LE CACHEUX Corentin"},{"id":99517,"num":"A34635JD","reference":"FC-183","title":"Acute Kidney Injury in the setting of Tumor Lysis Syndrome: impact on long-term outcomes","formatedAuthors":"Anaise BLOUET (3), Charlotte BOUD'HORS (4), Marie LEMERLE (5), Aline SCHMIDT (6,7), Achille KOUATCHET (5), Jean-François AUGUSTO (4), Corentin ORVAIN (6,7), Julien DEMISELLE (1,2)
(1) Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, Strasbourg, FRANCE ; (2) INSERM UMR 1260 Regenerative Nanomedecine (RNM), FMTS, Strasbourg, FRANCE ; (3) Onco-hématologie, Strasbourg Oncologie libérale, Strasbourg, FRANCE ; (4) Service de Néphrologie, Dialyse, Transplantation, CHU Angers, Angers, FRANCE ; (5) Service de Médecine Intensive Réanimation, Médecine Hyperbare, CHU Angers, Angers, FRANCE ; (6) Service des Maladies du sang, CHU Angers, Angers, FRANCE ; (7) CRCINA, INSERM U1232, Université de Nantes, Université d'Angers, Angers, FRANCE","contentIntroduction":"Acute kidney injury (AKI) is the main complication of tumor lysis syndrome, and is associated with high mortality and short term morbidity. However, the impact of AKI in this setting with long-term outcomes is poorly investigated.","contentPatientsMethods":"We collected and analyzed data of a retrospective monocentric cohort of adult patients, hospitalized between January 2007 and December 2017, who survived to an episode of tumor lysis syndrome. Tumor lysis syndrome was defined according to Cairo and Bishop criteria (1). For each patient, we recorded the occurrence of death, hematological disease progression, and modification in further chemotherapy regimen. In addition, we recorded renal function evolution, every three month during the first year, then annually. Chronic kidney disease was defined as an estimated glomerular filtration rate under 60 ml/min/1,73m2 (eGFR CKD-EPI). We compared patient’s evolution (survival, progression free survival, modification of chemotherapy regiment and chronic kidney disease occurrence) according to AKI occurrence (AKI group) or not (no AKI group) during the initial tumor lysis syndrome episode.","contentResultats":"115 patients were included in this analysis. Acute leukemia and non Hodgkin lymphoma accounted for 84% of malignancies. Median duration of follow-up was 24,8 months (IQR 25-75 months [4.4-70.5]). During the initial tumor lysis syndrome episode, 57 patients experienced AKI. AKI and no AKI groups were similar at baseline, and in tumor lysis syndrome management. \n At the end of follow-up, mortality in the AKI group was 59,6% and 55,4% in the no AKI group (p=0,644). Disease progression occurred in 44,4% and 39,2% in the AKI and no AKI groups, respectively (p=0,587).\n We found a modification of chemotherapy regimen in 18 patients, only in the AKI group. Among these patients, persistent renal failure was considered as an additional comorbidity leading to palliative care in 8 of them.\n Renal function evolution was available in 81 patients, with a median follow-up of renal function of 39.9 months (IQR [25-75]: 13.2-78.7 months). CKD was observed in 21 patients (25.9%). CKD was mostly diagnosed during the first year after TLS (12/21 patients). No difference between AKI and no AKI groups was observed in CKD occurrence.","contentDiscussion":"AKI during tumor lysis syndrome was strongly associated with modifications in chemotherapy regimen. We found no impact of initial AKI on major patient’s centered outcomes, but our study may be underpowered.","contentConclusion":"AKI during tumor lysis syndrome impacts further chemotherapy regimen. Of note, more than one fourth of patients developed chronic kidney disease.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1213","session":"FLASH COM - Devenir des pathologies malignes admises en réanimation","theme":"Oncologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. British Journal of Haematology. 2004;127(1):3?11.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DEMISELLE Julien"},{"id":99518,"num":"A34312SB","reference":"FC-184","title":"A multicentric prospective observational study of diagnosis and prognosis features in ICU mesenteric ischemia: the DIAGOMI study.","formatedAuthors":"Simon BOURCIER (1,2), Guillaume ULMANN (4), Matthieu JAMME (5), Guillaume SAVARY (1), Marine PAUL (1), Sarah BENGHANEM (1), Jean-Rémi LAVILLEGRAND (3), Matthieu SCHMIDT (2), Charles-Edouard LUYT (2), Eric MAURY (3), Alain COMBES (2), Frédéric PÈNE (1), Luc CYNOBER (4), Nathalie NEVEUX (4), Alain CARIOU (1)
(1) Medical intensive Care Unit, Cochin Hospital, AP-HP, Paris, FRANCE ; (2) Assistance Publique-Hôpitaux de Paris, AP-HP, Pitié-Salpêtrière Hospital, Médecine Intensive Réanimation, Paris, FRANCE ; (3) Assistance Publique-Hôpitaux de Paris, APHP, Saint-Antoine Hospital, Médecine Intensive Réanimation, Paris, FRANCE ; (4) Clinical Chemistry Department, Hôpital Cochin, AP-HP Centre, Université de Paris, Paris, FRANCE ; (5) Réanimation polyvalente, Hôpital Privé de l’Ouest Parisien, Ramsay Générale de santé, Trappes, FRANCE","contentIntroduction":"Non-occlusive mesenteric ischemia (NOMI) is a challenging diagnosis and is associated with extremely high mortality in critically ill patients, particularly due to delayed diagnosis and when complicated by intestinal necrosis. Citrulline and intestinal-fatty acid binding protein (I-FABP) have been proposed as potential promising biomarkers but have never been studied prospectively in this setting.","contentPatientsMethods":"We conducted a prospective observational study in 3 tertiary ICU centers. Diagnosis features and outcomes were compared according to NOMI, intestinal necrosis or ruled out diagnosis using stringent classification criteria.","contentResultats":"Diagnosis of NOMI was suspected in 61 patients and confirmed for 33 patients, with intestinal necrosis occurring in 27 patients. Clinical digestive signs, routine laboratory results and CT signs of mesenteric ischemia didn’t discriminate intestinal necrosis from ischemia without necrosis. Plasma I-FABP was significantly increased in presence of intestinal necrosis (AUC 0.83 [0.70–0.96]). A threshold of 3114pg/mL showed a sensitivity of 70% [50–86], specificity of 85% [55–98], a negative predictive value of 58% [36–93] and a positive predictive value 90% [67–96]. Necrosis resection was significantly associated with ICU survival (38.5%), whereas no patient survived without intestinal resection (HR = 0.31 [0.12–0.75], p = 0.01).","contentDiscussion":"","contentConclusion":"In critically ill patients with suspected NOMI, intestinal necrosis was associated with extremely high mortality, and increased survival when intestinal resection was performed. Elevated plasma I-FABP was associated with the diagnosis of intestinal necrosis. Further studies are needed to set plasma I-FABP threshold valuable in clinical-decision making.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOURCIER Simon"},{"id":99519,"num":"A34588EJ","reference":"FC-185","title":"Relationship between the rate of full stomach and daily SOFA in the enteral-fed ICU patient.","formatedAuthors":"Emilie JOFFRÉDO (1), Xavier DALSHEIMER (2), Lionel BOUVET (3), Charles-Hervé VACHERON (1), Anne-Claire LUKASZEWICZ (2), Bernard ALLAOUCHICHE (1)
(1) Centre Hospitalier LYON Sud, Pierre-Bénite, FRANCE ; (2) Hôpital Edouard Herriot, Lyon, FRANCE ; (3) Hôpital Louis Pradel, Bron, FRANCE","contentIntroduction":"The provision of adequate nutrition is an important part of the management of intensive care patients. Enteral nutrition (EN) is the preferred mode of feeding in these patients. However, some patients have an ileus that causes gastric stasis, which can lead to reflux of nutritional fluid with risks of micro-inhalation. Ultrasonographic measurement of antral cross-sectional area (ACSA) is an easy and reliable bedside procedure to estimate the rate of full stomach in critically ill patients receiving EN in 30-degree head-of-bed elevation and supine position.This technique is already well recognised.\n \n The aim of this work was to analyze the relationship between the rate of full stomach and the SOFA score and its impact on the tolerance of enteral nutrition.","contentPatientsMethods":"This prospective observational cohort study received approval (n°: L16-174) from the ethics committee (Comité pour la Protection des Personnes Sud-Est IV, Centre Léon Bérard, Lyon, France) and was registered in the public registry ClinicalTrials.gov, no. NCT03205592. In this prospective multicenter study, adult patients under mechanical ventilation were included, except supramesocolic surgery patients. Ultrasound examination of the gastric antrum was daily measured for five days long.\n Correlation was computed according to the method described by Bland and Altman specifically designed in order to compute correlation coefficient for repeated observation. Briefly, the coefficients of correlation (r) were estimated by modeling the effect of the gradient on the severity and introducing the patient as a dummy variable. Then, the coefficient was computed by the square root of the sum of square of the gradient /(sum of square of the gradient + residual sum of square) , and the p value derived from the F test in the associated analysis of variance table of the model.","contentResultats":"Thirty-five patients were analyzed : age = 61±14, 9 female, SAPS 2=40±17, admission SOFA=4±2. The incidence of full stomach varied between 77 to 89% during the follow-up period.\n \n The repeated measures correlation was 0.087, p=0.38 (figure 1). We found no relation between rate of full stomach and the incidence of ventilator-associated pneumonia or vomiting.\n \n The incidence of full stomach was not influenced by diabetes, Covid, sepsis, trauma, sedation, norepinephrine, renal replacement therapy or prone position.","contentDiscussion":"","contentConclusion":"Full stomach was frequently found but had no association with the SOFA score nor pneumonia or vomiting in enteral fed ICU patients.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"JOFFRÉDO Emilie"},{"id":99520,"num":"A34531AS","reference":"FC-186","title":"Extravascular lung water predicts progression to acute respiratory distress syndrome in critically ill cirrhotic patients.","formatedAuthors":"Alix SCHOULMANN (1), Rémi PLATTIER (1), Rodolphe ANTY (1)
(1) Hopital Archet 2, Nice, FRANCE","contentIntroduction":"Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure caused by a protein-rich alveolar edema fluid. Its incidence is variable and often related to a poor outcome. Extravascular lung water (EVLW) estimated by transpulmonary thermodilution using the PiCCO device is a hallmark of lung edema, and can help to predict the progression to lung injury in patients with risk factors. It is also an independent prognostic factor, and can further be used to guide fluid management. Thereby, we aim to evaluate the reproducibility of EVLW’s usefulness in critically ill cirrhotic patients.","contentPatientsMethods":"The medical records of 90 critically ill cirrhotic patients who benefited of haemodynamic monitoring using the PiCCO device from January 2013 to November 2019 were retrospectively reviewed. Independent risk factors and outcomes were then analyzed according to whether their EVLW value on ICU admission was greater than 10 mL/kg or not.","contentResultats":"An EVLW > 10 ml/kg on ICU admission is associated with ARDS (32% vs 8% p < 0,01), and with the onset of ARDS during hospital stay (66% vs 33% p < 0,01). Using a ROC curve, an EVLW cutoff of 10 ml/kg has been defined with the best sensitivity (74%) and specificity (62%) threshold. There is no difference between the groups regarding ICU mortality rate (51% vs 55%, p = 0,71), nor regarding the proportion of patients with cirrhotic ascites (61% vs 73%, p = 0,21 et 78 %, p = 0,95) or with pleural fluid (39% vs 24%, p = 0,14 et 66% vs 47%, p = 0,072), respectively on ICU admission and during the stay. In multivariate analysis, TIPSS history and ARDS during hospital stay were both independent risk factors of EVLW > 10 ml/kg (OR = 7,7 [1,36 – 43] ; p = 0,02 and OR = 4,9 [1,9 – 12,6] ; p = 0,001 respectively).","contentDiscussion":"","contentConclusion":"An EVLW > 10 ml/kg on ICU admission is associated with the onset of ARDS in critically ill cirrhotic patients, without interference in the measure from cirrhotic ascites or pleural fluid.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526-2533.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Monnet X. Transpulmonary thermodilution: advantages and limits. Published online 2017:12.","presentateur":"SCHOULMANN Alix"},{"id":99521,"num":"A34453BM","reference":"FC-187","title":"Liver transplantation for critically ill cirrhotic patients: results from the French transplant registry","formatedAuthors":"Thierry ARTZNER (1), Camille LEGEAI (2), Corinne ANTOINE (2), Carine JASSERON (2), Baptiste MICHARD (1), François FAITOT (1), Francis SCHNEIDER (1), Philippe BACHELLIER (1), Vincent CASTELAIN (1)
(1) CHU Strasbourg, Strasbourg , FRANCE ; (2) Agence de la Biomédecine , Saint Denis , FRANCE","contentIntroduction":"This study describes the population of cirrhotic patients who were transplanted from the ICU in France. It identifies pre-transplant risk factors of post-transplant mortality and describes geographic variations in ICU transplant activity.","contentPatientsMethods":"Cirrhotic patients transplanted between 2008 and 2018 were included through the national transplant registry. The demographic, clinical and biological characteristics of the patients transplanted from the ICU were compared to cirrhotic patients who were transplanted from home or from the hospital. Risk factors of post-transplant one-year mortality were identified in uni- and multivariable analysis within the population transplanted from the ICU. Funnel plots were used to illustrate center-specific differences in ICU transplant activity.","contentResultats":"1,047 cirrhotic patients were transplanted from the ICU during the study period. While the national rate of transplants performed from the ICU was 14.3%, the absolute number and the proportion of cirrhotic patients transplanted from the ICU varied significantly from one center to another, ranging from 6.6% to 22.8% (p<0.05) (cf. figure). The one-year post-LT survival rate for cirrhotic patients transplanted from the ICU was significantly lower compared to cirrhotic patients transplanted from the hospital and from home (77.1% vs 88.0% vs 89.8% respectively, p<0.0001). Three recipient associated independent risk factors of one-year post-LT mortality were identified in the population transplanted from the ICU: age > 50 years (HR 1.65, 95%CI 1.16-2.36), p = 0.005), diabetes (HR 1.46, 95%CI 1.07-1.98, p = 0.02) and intubation (HR2.12, 95%CI 1.62-2.78), p<0.001). Donor age was also independently associated with mortality (HR 1.01, 95%CI 1.01-1.02, p<0.001).","contentDiscussion":"","contentConclusion":"This study underlines the increased post-transplant mortality among cirrhotic patients transplanted from the ICU. It identifies four clinically pertinent independent risk factors associated with post-transplant mortality in this specific sub-group of transplant candidates. Finally, it illustrates how diverse the landscape of liver transplantation for critically ill cirrhotic patients is across a single country, despite a unified allocation algorithm.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MICHARD Baptiste"},{"id":99522,"num":"A34450BM","reference":"FC-188","title":"Pretransplant Intensive Care Unit Management and Selection of Grade 3 Acute-on-Chronic Liver Failure Transplant Candidates","formatedAuthors":"Baptiste MICHARD (1), Thierry ARTZNER (1), Mathilde DERIDDER (1), Camille BESCH (1), Pietro ADDEO (1), Vincent CASTELAIN (1), Max GUILLOT (1), Justine LEROUX (1), Jean Etienne HERBRECHT (1), Ralph JANSSEN LANGENSTEIN (1), Maleka SCHENCK (1), Philippe BACHELLIER (1), Francis SCHNEIDER (1), Francois FAITOT (1)
(1) CHU Strasbourg, Strasbourg , FRANCE","contentIntroduction":"The aim of this study is to report on the liver transplant (LT) activity and post-LT outcome over time of grade 3 acute-on-chronic liver failure (ACLF3) patients in the largest single center cohort of patients transplanted with ACLF3 published in the literature. It aims at showing how pre-LT intensive care unit (ICU) management impacts post-LT outcome, in particular through monitoring the transplantation for ACLF3 model (TAM) score, which is based on the recipient’s age, arterial lactate level, white blood cell count and respiratory status","contentPatientsMethods":"100 consecutive patients who had ACLF3 at the time of liver transplant between 2007 et 2019 were included retrospectively. The cohort was divided in 2 periods, with 50 patients in each period.","contentResultats":"There was a sharp increase in the number of ACLF3 patients transplanted over the course of the study period (from 4.2 to 12.4 patients transplanted with ACLF3 per year), and significantly higher one-year post-LT survival in the second period compared to the first period (respectively 86% vs 66%, p=0.035). Interestingly, patients during both periods had similar severity profiles and scores, apart from a significantly lower number of patients with TAM scores>2 at the time of LT in the second period compared to the first period. In addition, patients’ whose clinical condition improved in the ICU (with a TAM score being downstaged between admission and LT) had significantly higher post-LT survival rates than those whose TAM score stayed the same or increased: respectively 88% vs. 70% (p=0.042).\n Finally, the predictive power of the TAM score increased as critically ill cirrhotic patients were closer to the time of LT (cf. figure). In particular, the TAM score was most predictive immediately prior to LT (at the time of organ proposal), with significantly higher survival rates for patients with TAM score 0-2 vs. TAM score>2: respectively 85% vs. 8% (p<0.0001).","contentDiscussion":"","contentConclusion":"This study shows a learning curve in LT for ACLF3 patients, with optimized ICU management and patient selection leading to increased numbers of LTs for ACLF3 patients and improved post-LT outcomes. It delineates how the TAM score can be used in practice to identify the optimal transplantability window for ACLF3 patients. It shows that the decision to transplant candidate with ACLF3 should not be made prematurely close to ICU admission but rather at the time of organ proposal and that patients whose clinical state improves in the ICU have better post-LT survival.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MICHARD Baptiste"},{"id":99523,"num":"A34645CM","reference":"FC-189","title":"Predictors of early mortality after liver transplantation for acute liver failure","formatedAuthors":"Charlotte MOULIADE (1,2,3), Sophie-Caroline SACLEUX (1,2,3), Marie-Amélie ORDAN (1), Marc BOUDON (1,2,3), Audrey COILLY (1,2,3), Valerie CAILLEZ (1,2,3), Didier SAMUEL (1,2,3), Faouzi SALIBA (1,2,3), Philippe ICHAI (1,2,3)
(1) AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire, Liver Intensive Care Unit, Villejuif, FRANCE ; (2) INSERM Unité 1193, Université Paris-Saclay , Villejuif, FRANCE ; (3) DHU Hepatinov, Villejuif, FRANCE","contentIntroduction":"After liver transplantation for acute liver failure (ALF), the majority of deaths occur early, in the days and weeks after surgery, due to organ dysfunctions or failures at the time of transplantation.","contentPatientsMethods":"Between 2010 and 2021, 105 consecutive patients (62 women, 43 men, mean age 41.5 years) from a single center, with ALF registered for emergency liver transplantation were studied. Epidemiological, clinical, biological and radiological characteristics were collected upon admission, at registration on the transplant list and at the time of transplantation. The objective was to determine the predictive factors associated with 7-day mortality following the liver transplantation.","contentResultats":"The cause of ALF was paracetamol in 42 patients and non paracetamol in 63. Ninety-eight (93.3%) patients presented hepatic encephalopathy. Mean PT at admission was 17%. The mean IGS 2 and SOFA scores were 45.4 and 9.8 respectively. All fulfilled the criteria for liver transplantation (King’s college and/or Clichy-Villejuif criteria). At registration for the liver transplant, 53 patients (50.5%) were treated with renal replacement therapy, 44 (41.9%) received vasopressor support, and 72 (68.6%) were on mechanical ventilation. Sixty-four patients were transplanted, 15 died prior to liver transplantation and 26 improved without liver transplantation. Eight patients died following liver transplantation. The main causes of death were: multi-organ failure (60.9%), brain death (26.1%), ARDS (8.7%) and ventricular fibrillation (4.3%). Of these patients, 6 died within 7 days of transplantation and 2 after 8 days. The predictors of early mortality (day 7) at the time of transplantation in univariate analysis were: anuria (p = 0.018), low pH (p = 0.038), low bicarbonate level (p = 0.0006) and high lactate level (p = 0.01). Three events occurring before liver transplantation were associated with an increased risk of early mortality: cardiopulmonary arrest, total hepatectomy with portocaval anastomosis for toxic liver and extensive digestive ischemia. An increase in catecholamine doses was also associated with early mortality, although this association was not statistically significant.","contentDiscussion":"","contentConclusion":"This single-center study made it possible to highlight several predictive factors of early mortality after liver transplantation for ALF. The sample size was the main limitation of this study, and a multicenter study is needed to determine independent risk factors.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MOULIADE Charlotte"},{"id":99524,"num":"A34492RP","reference":"FC-190","title":"Gut microbiota composition but not ? diversity is linked to subsequent occurrence of ventilator-associated pneumonia in critically patients","formatedAuthors":"Arthur ORIEUX (1), Raphaël ENAUD (1), Sébastien IMBERT (1), Philippe BOYER (1), Erwan BEGOT (1), Adrian CAMINO (1), Alexandre BOYER (1), Patrick BERGER (1), Didier GRUSON (1), Laurence DELHAES (1), Renaud PRÉVEL (1)
(1) CHU Bordeaux, Bordeaux, FRANCE","contentIntroduction":"Ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in critically ill ventilated patients carrying high morbidity and an increase in healthcare costs. Oro-pharyngeal and lung microbiota have been demonstrated to be associated with VAP occurrence but gut microbiota involvement has not been investigated so far despite the relevance of the gut-lung axis in human health and diseases. The aim of this study is thus to compare the composition of the gut microbiota between patients who will subsequently develop VAP and those who will not.","contentPatientsMethods":"A rectal swab was performed for routine faecal ESBL-E carriage screening at admission of every consecutive patient into intensive care unit (ICU) from October 2019 to March 2020. After DNA extraction, V3-V4 and ITS2 regions were amplified by PCR. Deep-sequencing was performed on MiSeq sequencer (Illumina®); data were analysed using DADA2 pipeline.","contentResultats":"Among 255 patients screened, 42 (16%) patients with invasive mechanical ventilation for more than 48 hours were included, 18 (43%) with definite VAP and 24 without (57%). Patients with subsequent VAP had similar gut bacteriobiota and mycobiota α-diversities than those who will not develop VAP but gut mycobiota was dissimilar between those 2 groups. The presence of Megasphaera massiliensis was associated with the absence of VAP occurrence whereas the presence of Bifidobacterium breve, Peptostreptococcus anaerobius, Enterococcus avium, Alternaria sp. and Saccharomyces kudriavzevii was associated with subsequent VAP.","contentDiscussion":"","contentConclusion":"The composition of the gut microbiota, but not α diversity, differs between critically ill patients who will subsequently develop VAP and those who will not. This study encourages for large multicentre cohort study investigating the role of gut-lung axis and oro-pharyngeal colonization in the development of VAP in ICU patients and identify potential probiotic candidates for tailored prevention of VAP.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ORIEUX Arthur"},{"id":99525,"num":"A34379NM","reference":"FC-191","title":"Decontamination regimen and MDR environemental contamination : a sink survey","formatedAuthors":"Nicolas MASSART (1), Clarisse DUPIN (1), Veronique MARIE (1), Nicolas BARBAROT (1), Francois LEGAY (1), Pierre FILLATRE (1)
(1) CH Saint-Brieuc, Saint-Brieuc, FRANCE","contentIntroduction":"Despite a large number of scientific data supporting clinical benefit of selective decontamination in ICU patients with a decreased risk of multi-drug resistant micro-organisms acquisition, data regarding environmental impact are scarce. We aim to provide a better knowledge on the relationship between decontamination regimen and environmental contamination.","contentPatientsMethods":"We conducted an observational analysis in a 14 beds French polyvalent ICU in Saint-Brieuc, Bretagne, France. As of 05th of May 2021, patients with expected mechanical ventilation duration over 24 hours received multiple site decontamination (MSD) regimen. MSD is a variant of selective digestive decontamination that included topical antibiotics (gentamycin, polymyxin and amphotericin B) 4 times daily in the oropharynx and the gastric tub, without systemic antibiotic, in addition with a daily 4% chlorhexidine bodywash and a 5-day intra nasal mupirocin course. Two point prevalence study of sink contamination were performed on June 26th 2020 (pre-implementation) and October 20th 2021 (post-implementation) in the 24 sinks of the unit, at least 48 hours after last disinfection procedure.","contentResultats":"Samples from the pre-implementation period showed a higher rate of ESBL-PE with 12 sinks (50%) positive for 13 extended spectrum betalactamase producing enterobateriaceae (ESBL-PE) specimens as compared with 4 sinks (17%) containing 4 ESBL-PE during post-implementation period (Macnemar paired test = 0.043). Conversely, the number of samples positives for imipenem resistant Pseudomonas aeruginosa (IRPA) increased 1 (4%) and 8 (33%) positives sinks in the pre and post-implementation periods respectively (Macnemar paired test =0.046) (Figure). Of note, they were 11 Pseudomonas aeruginosa infections and 1 ESBL-PE infection during 6 months pre-implementation (3112 patients-days) as compared with 2 Pseudomonas aeruginosa and 1 ESBL-PE infections in the 6 months post-implementation (2196 patients-days) (p=1 for ESBL-PE infections and p = 0.023 for PA, poisson regression test).","contentDiscussion":"Previous studies already reported a diminution of colonization with Gram-negative resistant bacteria in patients receiving decontamination regimens. Decrease in ESBL-PE sink colonization may be secondary to a decrease of patient-to-sink ESBL-PE transmission. Despite a diminution in the incidence of Pseudomonas aeruginosa infections between both periods, there are concerns regarding the increased in IRPA in the sinks. A study previously suggested that exposure to common disinfectant lead to expression of outer membrane protein OprR, giving potential resistance to carbapenems.","contentConclusion":"In conclusion, we described for the first time a diminution of ESBL-PE but an increased in IRPA sink contamination with MSD regimen including topical antibiotic and chlorhexidine body wash.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1214","session":"FLASH COM - Foie, transplantation et microbiote","theme":"Digestif","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MASSART Nicolas"},{"id":99526,"num":"A34718is","reference":"FC-192","title":"Echocardiography in the Time of COVID-19.","formatedAuthors":"Ines SDIRI (1), Nizar FITOUHI (1), Amira DRIDI (1), Sana LAROUI (1), Sonia OUERGHI (1), Tahar MESTIRI (1)
(1) hopital ariana abderahmen memi, Sfax, TUNISIE","contentIntroduction":"Many published studies during the Covid-19 pandemic have focused on the respiratory component and their management while the hemodynamic component has had a major impact(1). Despite the important incidence of cardiac complications, few studies have reported the place of echocardiography in Covid-19 patients(2). Our study to report the echo graphic findings in severe covid-19 patients.","contentPatientsMethods":"This is a retrospective descriptive study conducted at the medical intensive care unit of circumstance Hospital, between January 1, 2021 and December 31, 2021. Were included the confirmed covid-19 patients of severe form and having benefited from a cardiac echography at the admission. An evaluation of the left ventricular function, the right one, the filling pressures, the valves and the pericardium.","contentResultats":"300 results were collected. Mean age was 57 years, 53.6% male. The BMI was 30.84. Comorbidities were hypertension 37,3%, diabetes 33,1% and cardiovascular pathologies 14%. The mean PaO2/FiO2 ratio was 123 and the CT scan injury was 71.12%. The use of mechanical ventilation was 57,7% and amines 62,8%. The average length of stay was 10 ± 8 days. The incidence of thrombi-embolic events was 22,1%. Mortality was 45%. Cardiac ultrasound was totally transthoracic. LV ejection function was impaired in 20.8% (<50% in women and <55% in men). Septal hyperkinesia was observed in 4% revealing ACS. 3% had acute pulmonary heart disease as evidenced by the presence of a paradoxes septum. 31.6% had relaxation disorders and 1% had compliance disorders. The evaluation of the filling pressures was found 33.7% in the gray zone with 2% elevated. The patients were in hypovolemia mostly 78.6% objectified by the inferior vena cava of diameter lower than 15cm. PAH was found in 10% of cases. Valvulopathies were 10.9%, dominated by mitral insufficiency 42% and tricuspid insufficiency 58% minimal justified by ARDS. Pericardial effusion was found in 13.9%, of minimal to moderate abundance.","contentDiscussion":"","contentConclusion":"Our study underlines the contribution of cardiac ultrasound in severe covid-19 which resides essentially to detect cardiac complications, the repercussion of ARDS in the hemodynamics and guide the adequate management.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"J Am Soc Echocardiogr. août 2020;33(8)","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"J Am Coll Cardiol. 19 janv 2021;77(2)","presentateur":"SDIRI Ines"},{"id":99527,"num":"A34432bb","reference":"FC-193","title":"The contribution of Tocilizumab in treatment of patients with a SARS-COV2 infection","formatedAuthors":"Bouthaina BOUCHECH (1), Ameni CHTOUROU (1), Rania DAMMAK (1), Hichem KOLSI (2), Rahma DERBEL (1), Oumaima BEN OMOR (2)
(1) hopital hbib bourguiba, Sfax, TUNISIE ; (2) hopital de campagne Slim Chaker, Sfax, TUNISIE","contentIntroduction":"SARS-COV2 virus is responsible for hypoxemic pneumonia that can evolve into an acute respiratorydistress syndrome \n The Tocilizumab is indicated in the treatment of severe syndromes caused by cytokine release that’s induced by CAR-T lymphocytes and therefore\n the objective of this study is to determine the contribution of this molecule in the treatment of critical patients infected with SARS-COV2","contentPatientsMethods":"it’s a descriptive retrospective study including 20 patients hospitalized in an intensive care unit for a SARS-COV2 pneumonia during the period extending from March 2021 to October 2021.\n These patients have received 2 doses of Tocilizumab equivalent to 8mg per kg with an interval of 48 hours between the two doses.\n The inclusions criteria are patients with an elevated level of IL6 (superior to 7pg/ml), hospitalized in an intensive care unit, under high oxygen flows (superior to 10l/min).\n The exclusion criteria are the presence of a bacterial infection, hepatocellular failure, thrombocytopenia , pregnant women and intubated patients","contentResultats":"our study included 20 patients with an age average of 56 years and a sex ratio of 1.16.\n These patients are classified ASAII at minimum . all patients were under corticoid .16 patients have had a thoracic scan revealing a lung damage extended on 25% to 50%.\n During their stay in the ICU, all of these patients presented with a respiratory deterioration between the third and 22nd day of evolution .80% of patients were under either a highflowoxygen or high concentration mask and 20% were under a noninvasive ventilation.\n Before the administration of the cure, their level of IL6 was between 12 and 107 pg/ml , the lth level of ASAT was between 18 and 76 and the level of AAT was between 12 and 73 \n The treatment was administered between day 5 and day 19\n The complications induced by the treatment were a respiratory deterioration in 80% of the cases, a nosocomial infection in15% , hepatic cytolysis in 10% , and anaphylactic choc in 5% \n After a week, 30% of patients were out of the ICU and put under oxygen with a flow between 6 and 15l/min while 70% needing a mechanic ventilation","contentDiscussion":"","contentConclusion":"In Tunisia the number of reported cases is still low.However, it is essential to conduct may clinical trials to evaluate the efficiency as well as the opportune moment of administration of tocilizumab in relation to the beginning of symptoms especially that this treatment isn’t risk free.","published_at":"2022-06-16T16:01:25.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:25.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 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(1) centre hospitalier mohammed V oujda , Oujda, MAROC","contentIntroduction":"Corona virus disease 19 (Covid-19) affects especially the respiratory tract, and induces lung injury which may progress to the acute respiratory distress syndrome (ARDS). Various treatment options were tried all over the world, corticosteroids had showed beneficial effects.\n The Objective of this study, is to compare the safety and efficiency of two corticosteroids: dexamethasone and prednisolone in the treatment of Covid-19 infection","contentPatientsMethods":"This retrospective and comparative study included 513 patients diagnosed with Covid-19 infection and were admitted to intensive care unit of our university hospital center of MOHAMMED VI Oujda from March 1, 2020, to December 31st, 2020.","contentResultats":"In this study, 513 cases were included, 230 patients were received methylprednisolone, and 283 were treated with dexamethasone. The median age in methylprednisolone group was 64 years, and 63 years in the second group treated with dexamethasone. Patients treated with dexamethasone had more critically lesions compared to patients treated with methylprednisolone (67.6%), these patients had a good evolution with a significant reduction of oxygen supplementation, lower use of invasive ventilation and a significant improvement in biological parameters. 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(1) Medical ICU, la Rabta hospital, Faculty of Medicine of Tunis, Tunis, TUNISIE ; (2) Deparetment of anesthesia, la Rabta hospital, Faculty of Medicine of Tunis, Tunis, TUNISIE","contentIntroduction":"COVID-19 pandemic has rapidly required an increased number of ICU admission and deaths. In view of this alarming situation, it became mandatory to develop prognostic models to evaluate critical COVID-19 patients. We aimed to study the characteristics and prognosis of adult patients with critical COVID-19 requiring hospitalization in ICU during 2nd, 3rd and 4th waves of the pandemic in order to identify the predictive factors of mortality.","contentPatientsMethods":"We retrospectively evaluate a cohort of consecutive COVID-19 critically ill patients admitted to ICU with a confirmed diagnosis of SARS-CoV-2 pneumonia. A multivariable regression model including demographic, clinical and laboratory findings was developed to assess the predictive value mortality of these variables using the ROC curves. Our main outcome was in ICU mortality.","contentResultats":"358 were included (genre-ratio=1.75, mean age=60+13 years, median BMI= 27.7 kg/m2 and SOFA=4 [3-6]). The most observed age class was 60-79 and 44% were obese. 72 (20%) had no antecedent. Arterial hypertension (40.2%) and diabetes (39.1%) were the most reported co-morbidities. The median time of respiratory distress from the symptomatology onset was 11 days [8-15]. Clinical signs were: dyspnea (94%), fever (72.6%) and cough (70.4%). The median P/F ratio was 90 [67-129.5] and 58.5% of patients were in severe ARDS. In 45% of cases, ground-glass opacities exceeded 50% in the chest CT. 218 patients (61%) required mechanical ventilation (MV) and among them 12 (5.5%) were successfully weaned. The most complications were shock (49%), acute kidney injury (31%) and ICU related infection (34%). The evolution was fatal in 64% of cases (n=229).\n In Multivariable Model: Tachycardia (HR> 99 bpm), an initial P/F ratio <107 and MV were the factors independently associated to mortality with respectively OR [95% CI] at 39.9 [1.2-1307], 424 [2,23-80560] and 2235 [2,74-181842]. Other factors tended to the significance: SOFA> 3.5 (OR = 292 [0.9-9715], p = 0.055), a lymphocyte count <555 el/mm3 (OR=92,3 [0.84-1073], p=0.059) and occurrence of shock (OR=119 [0.99-15679], p=0.055). The most predictive death factors were the use of MV (AUC/ROC = 0.904 [0.866-0.941], p<10-3, Se=90% and Sp=90.7%) and shock (AUC/ROC=0.854 [0.814-0.895], p<10-3 and Sp = 96.2%). The other variables had significant AUC/ROC but a low predictivity (table).","contentDiscussion":"","contentConclusion":"in our large series, independent factors of mortality were a deep hypoxemia, tachycardia, mechanical ventilation, and nearly to be significant were shock, presence with more than 3 organ dysfunctions and lymphopenia. The highly predictive death factors were MV and Shock.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TRIFI Ahlem"},{"id":99530,"num":"A34728RG","reference":"FC-196","title":"Characterization of Patients Who Return toemergency department Following Discharge from Hospitalization for COVID-19","formatedAuthors":"Mouna JERBI (1), Rezk GHORBEL (1), Emna GHARBI (1), Haifa SNOUSSI (1), Lobna AFFES (1), Bouthaina KESENTINI (1), Olfa CHAKROUN (1), Noureddine REKIK (1)
(1) centre Hospitalo-universitaire Habib Bourguiba sfax, Sfax, TUNISIE","contentIntroduction":"To describe the specific epidemiological profile of post-COVID patients consulting in the emergency room, the characteristics of the infectious episode, these repercussions on daily life as well as data concerning the symptoms, the problems and the reasons for consultation","contentPatientsMethods":"This is a descriptive prospective study collecting post-COVID patients, who presented to the medical emergency box, regardless of age and reason for consultation during the period from 1June to 30 August 2021.","contentResultats":"111 patients returned for emergency care after a median of 8±2 days, with 32,4% requiring in patient readmission. Mean age was 54 ±18 years, 42,9 % men. Their chronic medical conditions included hypertension 25 (22,5%), diabetes mellitus 26 (23,4%) and coronary artery disease 4 (3,6%). For the reasons for consultations in the emergency room, they were mainly represented by dyspnea on exertion (39%) .Main reasons for readmission were acute respiratory failure ( 25,2%), chest pain (25,2%) .The rate of thromboembolic complications arterial or venous in COVID-19 patients was ( 21 %). On readmission, rates of intensive care were 4 %.","contentDiscussion":"","contentConclusion":"The follow-up of post-COVID patients is very interesting. It makes it possible to identify different problems that can be classified as acute complications or a post-COVID syndrome, including respiratory distress. It requires monitoring and multidisciplinary care involving many specialties.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHORBEL Rezk"},{"id":99531,"num":"A32034AT","reference":"FC-197","title":"Vaccination against COVID-19: knowledge and perception of healthcare givers working in COVID sectors","formatedAuthors":"Ahlem TRIFI (1), Asma MEHDI (1), Lynda MASSEOUD (1), Amal MEFTEH (1), Eya SEGHIR (1), Emna ABID (1), Cyrine ABDENNEBI (1), Sami ABDELLATIF (1), Salah BEN LAKHAL (1)
(1) Medical ICU, la Rabta hospital, Faculty of Medicine of Tunis, Tunis, TUNISIE","contentIntroduction":"The generalization of vaccination against SARS-CoV-2 is one of the pillars of the strategy to fight against the virus spread and limit the morbidity and mortality. In this context, the role of caregivers is paramount by being a frequently requested source for information and influence. OBJECTIVE: To assess the knowledge and perception of healthcare givers (HCG) working in COVID sectors regarding the SARS-CoV-2 vaccine.","contentPatientsMethods":"Online survey targeting HCG working in the COVID sectors of Tunisia. The questionnaire was created on the Google-Forms platform exploring 3 sections: personal data, knowledge and perceptions about vaccination.","contentResultats":"282 HCG responded to the questionnaire. The majority were medical physicians (199 (70.5%) including seniors (n=106). The age group 18-39 years was predominant (68%) and the sex ratio (M/F) = 0.35. Medical HCG exercised in university hospitals in 230 cases, private (n = 15) and regional (n = 37) and intensive care accounted for 43% of the nature of COVID activity. Half (48%) contracted the virus SARS-CoV-2 and the clinical form was considered minor in 82% of cases and severe requiring resuscitation in 5 cases. 87% received their full dose and 45% were within 3-6 months of the 2nd dose. Pfizer-Biontech (48%), Sputnik (34%) and Chinese vaccines (13 %) were the most received. As for knowledge and opinions, there was a discrepancy between the medical and paramedical HCG: the second category was less convinced by the vaccination, recommended the vaccine less to their advice seekers, believed less that immunity would be better acquired by the disease than by the vaccine and had less confidence in science in the development of the anti-SARS-CoV vaccine. Twenty-five (9%) of the responders considered themselves to be anti-vaccine (medical HCG: 4 and paramedical HCG: 21) and the main reason was the lack of information about vaccines.","contentDiscussion":"","contentConclusion":"The existing perception and attitude of frontline health workers differ depending on medical or paramedical status. Motivation and positive influence were felt less by the second population. Measures are essential to minimize these gaps: more awareness programs adapt communication strategies, impose obligations? ...","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MASSEOUD Lynda"},{"id":99532,"num":"A34672AF","reference":"FC-198","title":"Mental health of intensive care professionals more than a year after the first peak of the health crisis","formatedAuthors":"Alicia FOURNIER (1), Victoire DELTOUR (1,2), Florent LHEUREUX (3), Fiona ECARNOT (4), Christine BINQUET (5,6), Jean Pierre QUENOT (5,7,8,9), Alexandra LAURENT (1)
(1) Laboratoire Psy-DREPI, Université de Bourgogne, Dijon, FRANCE ; (2) VCR EA 7403, Ecole de Psychologues Praticiens, ICP, Paris, FRANCE ; (3) Laboratoire de Psychologie, Université de Franche-Comté, Besançon, FRANCE ; (4) Département de cardiologie, Université de Franche-Comté, Besançon, FRANCE ; (5) INSERM, CIC1432, module Epidémiologie Clinique (CIC-EC), Dijon, FRANCE ; (6) CHU Dijon-Bourgogne, UFR des Sciences de Santé, Dijon, FRANCE ; (7) Service de Médecine Intensive-Réanimation, CHU Dijon-Bourgogne, Dijon, FRANCE ; (8) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, Université de Bourgogne, Dijon, FRANCE ; (9) Espace de Réflexion Éthique Bourgogne Franche-Comté, Dijon, FRANCE","contentIntroduction":"The health crisis linked to COVID-19 has significantly changed the organization and the context of care in intensive care units (ICU). New and numerous stressors have been added to the stressors already present in the units (Laurent et al. 2021). One of the specificities of this crisis is notably its duration and its uncertain outcome. In this context, acute and chronic stress have been combined, constituting the risk of developing stress-related disorders that become chronic in ICU professionals. The objective of this paper is to present the psychological impact of the health crisis on intensive care workers one year and two months after its first peak in France.","contentPatientsMethods":"Between 21 June and 19 July 2021, 840 professionals (physicians, residents, nurses, nurses’ aides, students, and nursing managers) in 48 French hospitals took part in the PsyCOVID-ICU study. An online questionnaire was administered online via the Limesurvey platform. We assessed the severity of PTSD symptoms (IES-R), burnout (MBI-HSS), perceived stressors (PS-ICU) and the support used to cope with professional stress (colleagues, hierarchy, entourage, hotline, psychologist).","contentResultats":"The results show that 60.24% of the professionals had burnout. Of these, 16.38% also had possible PTSD. Only 2.4% of the professionals had possible PTSD without burnout. Professionals who suffered from both possible PTSD and burnout perceived significantly more stress than other professionals (ps<.002). They were particularly sensitive to the perception of a heavy workload and difficulties related to human resources management. Most of these professionals turned to support from their colleagues and relatives (ps<.025) and the least to the hotline (ps<.001).","contentDiscussion":"","contentConclusion":"This study illustrates the long-term effects of the health crisis on the mental health of intensive care professionals. It highlights a population of ICU professionals who are particularly sensitive to stress in the ICU one year after the crisis and who suffer from post-traumatic stress and burnout.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Laurent A., Fournier A., Lheureux F, …. Quenot JP. (2021). Mental health and stress among ICU caregivers in France according to intensity of the COVID-19 epidemic. Annals of intensive care. 4;11(1):90. doi: 10.1186/s13613-021-00880-y.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"FOURNIER Alicia"},{"id":99533,"num":"A34433BM","reference":"FC-199","title":"Prediction of the location of infectious droplets and aerosols with computational fluid dynamics in the rooms of ICU patients","formatedAuthors":"Charlotte DE HARENNE (1), Alessandro GAMBALE (2), Maxime BOSSE (3), Maxime LISSON (4), Mouhsine LAMTIRI (3), Pauline PITTI (3), Pedro OBANDO VEGA (2), Axelle BERTRAND (1), Anne MAHIANE-BIDJA (1), Sophie KESSELER (1), Cécile MEEX (3), Eric HAUBRUGE (4), Claude SAEGERMAN (5), Daniel DESMECHT (6), Benoît MISSET (1)
(1) DEPARTMENT OF INTENSIVE CARE MEDICINE - CHU LIEGE, Liege, BELGIQUE ; (2) BUILDWIND SPRL, Brussels, BELGIQUE ; (3) DEPARTMENT OF MICROBIOLOGY - CHU LIEGE, Liege, BELGIQUE ; (4) TERRA RESEARCH CENTER - GEMBLOUX AGROBIOTECH - UNIVERSITY OF LIEGE, Gembloux, BELGIQUE ; (5) RESEARCH UNIT IN EPIDEMIOLOGY AND RISK ANALYSIS - FACULTY OF VETERINARY MEDICINE - UNIVERSITY OF LIEGE, Liege, BELGIQUE ; (6) DEPARTMENT OF PATHOLOGY - FACULTY OF VETERINARY MEDICINE - UNIVERSITY OF LIEGE, Liege, BELGIQUE","contentIntroduction":"SARS-CoV 2 is likely transmitted between humans through direct contact and/or infectious droplets and aerosols. Droplets are defined as particles over 5 µm and aerosols as particles less than 5 µm diameter. Our aim was to estimate the location of the particles within a real intensive care room when hosting a patient with COVID-19 and assess the presence of SARS-CoV-2 in these particules.","contentPatientsMethods":"We used the architectural features of several individual rooms of our Intensive Care department, the prescribed and measured heating, ventilation, and air-conditioning characteristics.\n We modeled the air flow and droplet dynamics using Computational Fluid Dynamics. Unsteady RANS, three-dimensional numerical simulations used a k-w SST turbulence model with heat transfer and buoyancy for natural convection. The computational domain included the room ventilation system with piping and vents, air leakage from the doors, and the main objects in the rooms. Air and surface samples for SARS-CoV-2 PCR were guided by the simulation.","contentResultats":"The measured HVAC characteristics in terms of air flow were different than the prescribed one. Simulations showed that droplets were mostly present on the workbenches and on the floor in front of the door, and that aerosols flew vertically towards the ceiling, stayed in suspension or followed the leakage around the doors. SARS-CoV-2 was searched in the rooms of 9 patients treated with high flow oxygen and nasal Ct between 17 and 31. PCR was positive in 10/25 (40%) surface and 3/15 (20%) air samples where it was expected by simulation, and in 1/5 (20%) surface and 0/12 air samples where it was not expected. Positive surfaces were air-extract units, the floor in front of the door and the nurse workbench. Positive air samples were over the patient’s head and in front of the door outside the room. Additional samples are underway to increase the prediction of the computational model.","contentDiscussion":"","contentConclusion":"In our institution, the observed HVAC characteristics are different from the prescribed ones. Taking the actual characteristics of the rooms into account and using a numeric 3-D simulation model, the use of a computational model accurately predicts locations where SARS-Cov-2 particles can be found.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1215","session":"FLASH COM - COVID-19","theme":"Soins intensifs","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DE HARENNE Charlotte"},{"id":99534,"num":"A34336CB","reference":"FC-200","title":"Impact of emotional stimulations on thirst in critically ill mechanically ventilated patient","formatedAuthors":"Côme BUREAU (1), Thomas SIMILOWSKI (1), Alexandre DEMOULE (1)
(1) Hôpital Universitaire Pitié-Salpêtrière, Paris, FRANCE","contentIntroduction":"Up to 70% of intensive care unit patients report thirst. Thirst provokes the urge to drink fluids. This multidimensional symptom is described in terms of intensity and dry mouth. Few studies have investigated thirst relief in intensive care unit patients and none has focused on mechanically ventilated (MV) patients Relieving thirst usually involves giving the patient something to drink; unfortunately, in this population, it is difficult to meet this need and alternative interventions are needed. Our objective was to evaluate and to compare the impact of auditory and a sensory stimulations on the intensity of thirst in critically ill patients undergoing invasive or non-invasive MV. This is an ancillary study of the “Sensopnea 2” study.","contentPatientsMethods":"Patients MV for more than 48 hours with a dyspnea intensity ≥40 mm on a visual analog dyspnea scale (Dyspnea-VAS) were included (inclusion criteria of the Sensopnea 2 study). Two visual analog scales (Thirst-VAS and Dry mouth-VAS) assessed thirst and dry mouth sensation. We studied the following interventions: 1) a relaxing standardized music piece vs. a \"pink\" noise as a control (auditory stimulation), and 2) fresh air directed toward the face vs. the thigh as a control (sensory stimulation). A washout period separated each condition.","contentResultats":"We included 46 patients, 19 tracheostomized (41%), 18 intubated (39%) and 9 under non-invasive ventilation (20%). Median (interquartile range) age was 63 years (54-73) and duration of mechanical ventilation was 33 days (7-49). Figure 1 shows Thirst-VAS and Dry mouth-VAS during sensory stimulation and auditive stimulation with their control. Compared to their respective control group the two intervention decreased Thirst-VAS: 1) auditory stimulation 20 [0-30] vs. 30 [0-40], p=0.0004 and 2) sensory stimulation 30 [20-50] vs. 40 [30-50], p=0.0025). Compared to their respective control group the two intervention decreased Dry mouth-VAS: 1) auditory stimulation 30 [10-40] vs. 40 [30-70], p=0.0002 and 2) sensory stimulation 30 [0-60] vs. 40 [30-60], p=0.0013).","contentDiscussion":"","contentConclusion":"In critically ill dyspneic MV patients, auditory and sensory stimulations decrease thirst and dry mouth sensation.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BUREAU Côme"},{"id":99535,"num":"A34391JP","reference":"FC-201","title":"Prevalence of low vitamin D level and outcomes impact in weaning unit after prolonged stay in ICU","formatedAuthors":"Jean-Baptiste PERETOUT (1), Karim NSSAIR (1), Razach ABDALLAH (1), Raphael LEPECQ (1), Laurence DONETTI (1), Mohamed LAISSI (1), Gérald CHOUKROUN (1)
(1) Hôpital Forcilles - Fondation Cognacq-Jay, Férolles-Attilly, FRANCE","contentIntroduction":"Recent studies suggest that low vitamin D level is associated with an increased risk of hospitalization, critical care use, enhanced systemic inflammation and mortality1,2. The objective of this study was to determine the prevalence of hypovitaminosis D and vitamin D deficiency in patients hospitalized in a respiratory weaning unit and the impact on weaning outcomes after a prolonged ICU stay.","contentPatientsMethods":"This is a prospective, descriptive cohort study of patients hospitalized in respiratory weaning unit after a prolonged ICU stay over the year 2021. Plasma 25-hydroxyvitamin D concentrations ([25(OH)D]) was collected from the 48-hour admission blood test. We defined hypovitaminosis D by [25(OH)D] < 30 ng/mL and vitamin D severe deficiency by [25(OH)D] < 10 ng/mL. We also compared the biological data and weaning outcomes of patients with hypovitaminosis D and patients with normal levels.","contentResultats":"We analyzed 136 patients (mean age 63 ± 12 years ; male 70% ; COVID 70%) hospitalized in a weaning unit for mechanical ventilation and/or tracheostomy after prolonged stay in the ICU.\n On admission, the prevalence of hypovitaminosis D was 88.3% (n=120), the prevalence of severe deficiency was 3.7% (n=5) and the mean [25(OH)D] was 20.7 ± 7.9 ng/mL. No statisticial difference on [25(OH)D] levels was found between patients with successful decannulation and those with failed decannulation: 20.7 ± 8.3 vs 20.7 ± 5.6 ng/mL (p=0.98).\n In hypovitaminosis D group, phosphorus was statisticaly lower than in the other group: 1,08 ± 0,32 vs 1,25 ± 0,27 p=0,035.\n No statistical difference was found on weaning outcomes (Table I).","contentDiscussion":"","contentConclusion":"The prevalence of hypovitaminosis D is major in weaning unit after a prolonged ICU stay. Among the other biomarkers, only phosphorus is lower in the deficient group probably related to its role in the metabolism of vitamin D. However, vitamin D deficiency does not appear to be a factor influencing weaning’s outcomes. Screening and treatment are still necessary in the treatment of long-term complications.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Bychinin MV, Klypa TV, Mandel IA, Andreichenko SA, Baklaushev VP, Yusubalieva GM, Kolyshkina NA, Troitsky AV. Low Circulating Vitamin D in Intensive Care Unit-Admitted COVID-19 Patients as a Predictor of Negative Outcomes. J Nutr. 2021 Aug 7;151(8):2199-2","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Pimentel GD, Dela Vega MCM, Pichard C. Low vitamin D levels and increased neutrophil in patients admitted at ICU with COVID-19. Clin Nutr ESPEN. 2021 Aug;44:466-468","presentateur":"PERETOUT Jean-Baptiste"},{"id":99536,"num":"A34463LM","reference":"FC-202","title":"Impact of time of administration and dose of desmopressin in brain-dead donors: a before-after study","formatedAuthors":"Laura MOLINA (1), Mario GENEIX (1), Marine LE PRINCE (1), Sebastien MOSCHIETTO (1), Florent MONTINI (1)
(1) Centre hospitalier d'Avignon, Avignon, FRANCE","contentIntroduction":"Diabetes insipidus is one of the complications of brain death. Its management consists in the introduction of desmopressin. There are no studies focusing on the dosage and timing of desmopressin administration in brain dead organ donors.\n It's possible that the earliest administration of desmopressin in relation to the diagnosis of central diabetes insipidus and at high doses may influence the hemodynamics of donors, their renal function and recipient in the short and long term. The objective of our study is to compare, after introducing a new protocol in 2018, the modalities of desmopressin administration in terms of time of introduction and dosage and then the impact on hemodynamics, donor renal function, and the impact on renal function of renal transplant recipients.","contentPatientsMethods":"We conducted a single center, retrospective study. In total 196 patients were included, with a diagnosis of brain death, during a period of 6 years.\n The protocol used during the first period between 2015 and 2017 was, after the diagnosis of diabetes insipidus, the infusion of a bolus of 1 µg of desmopressin, then 1ug every 6 hours according to evolution. The new protocol was infusion of a bolus of 2 µg of desmopressin then continuous infusion of 4 µg/24h, with the possibility of additional boluses.\n The data on the recipients was sent to us by the biomedicine agency.","contentResultats":"We found a statistically significant difference in the delay of desmopressin introduction (4H group 2015-2017 vs. 1H group 2018-2020), as well as in the total dosage administered (1 µg 2015-2017 vs. 4 µg 2018-2020). We found a significant difference in the administration of glucose solution (4L group 2015-2017 vs 2.5L group 2018-2020), as well as a significant difference in the dosages of noradrenaline administered (0,2 gamma/kg/min group 2015-2017 vs 0,1 gamma/kg/min group 2018- 2020 p = 0,04). We noted higher natremia in the first group, not significant (148mmol/l group 2015-2017 vs 146mmol/l group 2018-2020). However, we did not find any differences in the renal functions of the donors or recipients. The number of functional grafts at 1 year was higher in the 2018-2020 group.","contentDiscussion":"","contentConclusion":"This study, the first to compare 2 methods of desmopressin administration in brain-dead donors. It shows that increasing dosages and reducing the time of administration is safe, allows better haemodynamic management of donors and may improve long-term renal transplant outcomes.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MOLINA Laura"},{"id":99537,"num":"A34108JP","reference":"FC-203","title":"Right atrial Strain, renal doppler and worsening renal function in acute decompensated pulmonary hypertension","formatedAuthors":"Jérémie PICHON (1), Anne ROCHE (1), Nathan EBSTEIN (1), Athenais BOUCLY (1), Jonathan CORTESE (1), Mitja JEVNIKAR (1), Xavier JAIS (1), Olivier SITBON (1), David MONTANI (1), Marc HUMBERT (1), Laurent SAVALE (1)
(1) Hôpital Bicêtre APHP, Kremlin Bicêtre, FRANCE","contentIntroduction":"Although congestion has been identified as a main contributing element to the cardio-renal syndrome in acute right heart failure (RHF), right atrial (RA) mechanical performance has never been evaluated to predict worsening renal failure.","contentPatientsMethods":"The aim of our study was to analyze the prognostic value of RA Strain in precapillary pulmonary hypertension (PH) patients admitted in intensive care unit (ICU) for acute RHF at admission and at day three. Congestion was assessed by alteration of the intrarenal Doppler, sushepatic and portal vein flow. The primary endpoint was the occurrence of acute kidney injury (AKI) KDIGO I-III","contentResultats":"Among the 64 patients analyzed (66% female, age 60±16 years), all patients received intravenous diuretics and 36 (56 %) required inotropic and/or vasopressor support. At ICU admission, the median values of peak, conduit, boost RA Strain and RA ejection fraction (EF) were respectively 12% [8 – 20], -5% [7 – 4], -7% [10 – 4] and 31% [20 – 41]. There is a good interobserver correlation (Rho=0.94; p<0.01). Peak RA strain higher than median value was significantly associated with higher eGFR (p=0.02), lower renal resistive index (RRI; p=0.01), lower renal venous stasis index (RVSI; p<0.01) and lower volume excess ultrasound (VExUS; p<0.01). A primary endpoint event occurred in 17 patients (26%). Event rate was higher in low RA EF (p=0.02), in high RRI (p=0.01) and high RVSI (p<0.01) groups. At day 3, an increase in peak RA Strain and RA EF was both associated with fewer worsening of renal function. Patients with peak RA Strain >20% at admission does not develop AKI during the stay.","contentDiscussion":"","contentConclusion":"RA Strain seems to be an easy-to-use bedside and relevant tool for evaluation of cardio-renal syndrome. It could help to predicts worsening renal function in acute RHF","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PICHON Jérémie"},{"id":99538,"num":"A34355JL","reference":"FC-204","title":"Permissive hypotension during sepsis : impact on fluid balance and renal prognosis","formatedAuthors":"Laurene BLUM (1), Jean-Rémi LAVILLEGRAND (1), Geoffroy HARIRI (1), Tomas URBINA (1), Naike BIGE (1), Jean Luc BAUDEL (1), Bertrand GUIDET (1), Eric MAURY (1), Hafid AIT OUFELLA (1)
(1) APHP-CHU Saint Antoine, Paris, FRANCE","contentIntroduction":"The therapeutic management of sepsis includes control of the infectious source, fluid resuscitation associated with the introduction of catecholamines, primarily norepinephrine to maintain a mean arterial pressure (MAP>65 mmHg). However, this MAP target remains debated, especially since MAP is not a direct reflection of tissue perfusion. Some authors suggest that MAP should be adapted individually to tissue perfusion. The objective of our work is to evaluate if a strategy called permissive hypotension, which consists in tolerating a moderate arterial hypotension when peripheral perfusion is preserved, has an impact on the fluid balance and on the renal function.","contentPatientsMethods":"This was a single-center observational study. Patients with sepsis and MAP <65 mmHg after 30 mL/kg fluid resuscitation were included. We compared 2 groups of patients, a so-called Septic Shock group that received norepinephrine to maintain MAP >65 mmHg and a Permissive Hypotension group in whom moderate hypotension was tolerated. The volume of fluids administered and the renal outcome (diuresis and change in creatinine) during the first days of management were studied.","contentResultats":"Over a period of 1 year, 94 patients were included, 79 in the septic shock group and 15 in the permissive hypotension group. Severity, assessed by IGS II (60 [45-86] vs 45 [27-46], P=0.0001) and SOFA score (7 [5-10] vs 4 [1-6], P < 0.0001), was greater in the Septic Shock group, as was organ support: invasive mechanical ventilation (71% vs 0%, P < 0.0001) and extra-renal replacement therapy (20% vs 0%, P = 0.06). In univariate analysis, mortality was lower in the Permissive Hypotension group (0% vs. 38%, P=0.004) as was length of stay among survivors (3 [2-5] vs. 7 [4-14] days, P=0.0004).\n The volume of fluid administration before admission to the ICU did not differ between the 2 groups (26 [20-32] vs 24 [18-33] mL/kg, p=0.8. In contrast, during the first 6 hours in the ICU, the volume administered was significantly lower in the Hypotensive Permissive group (500 [0-1000] versus 1000 [500-1500], p=0.03). Renal function improved faster in the Permissive Hypotension group with a significantly lower KDIGO score at 48 hours (0 [0-1] vs. 1 [0-2] (p < 0.05). Blood creatinine levels were not different at discharge between the 2 patient groups.","contentDiscussion":"","contentConclusion":"Permissive hypotension in sepsis, in the absence of clinical peripheral perfusion abnormalities, is very well tolerated. It is not accompanied by excess vascular filling or negative impact on renal function.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BLUM Laurene"},{"id":99539,"num":"A34314RB","reference":"FC-205","title":"Soluble TREM-1 plasma levels are associated with acute kidney injury, acute atrial fibrillation and prolonged ICU stay after cardiac surgery","formatedAuthors":"Marie VANDESTIENNE (2), Rayan BRAIK (1,2), Jean-Rémi LAVILLEGRAND (1,2), Rida EL RIFAI (2), Geoffroy HARIRI (1), Lisa RAIA (1), Zoe DEMAILLY (3), Eric TARTOUR (1,2), Nadine BEN HAMOUDA (1,2), Alain TEDGUI (2), Adrien BOUGLÉ (1), Fabienne TAMION (3), Thomas CLAVIER (3), Hafid AIT-OUFELLA (2)
(1) APHP, Paris, FRANCE ; (2) PARCC INSERM, Paris, FRANCE ; (3) CHU Rouen, Rouen, FRANCE","contentIntroduction":"Cardiopulmonary bypass (CPB) during cardiac surgery leads to deleterious systemic inflammation. We hypothesized that TREM-1, a myeloid receptor, is engaged during CPB and shed in plasma.","contentPatientsMethods":"During non-urgent cardiac surgery, we assessed 1/the kinetics of myeloid TREM-1 expression (flow cytometry), 2/ the relationship between soluble (s)TREM-1 and pro-inflammatory cytokine plasma levels (ELISA) and 3/ the association between sTREM-1 levels and postoperative outcome.","contentResultats":"In a first pilot study (N=11), TREM-1 expression on neutrophils decreased between H0 and H2 while sTREM-1 plasma levels increased. In a second prospective cohort (N=46), sTREM-1 levels increased at H2 and at H24 (p<0.001). IL-6, IL-8, G-CSF and TNF-a, but not IL-1b, significantly increased at H2 compared to H0 (p<0.001), but dropped at H24. Principal component analysis showed a close relationship between sTREM-1 and IL-8. Three patterns of patients were identified : Profile 1 with high baseline sTREM-1 levels and high increase and profile 2/3 with low/moderate baseline sTREM-1 levels and no/moderate increase overtime. Profile 1 patients developed more severe organ failure after CPB, with higher norepinephrine dose, higher SOFA score and more frequently acute kidney injury at both H24 and H48. Acute atrial fibrillation was also more frequent in profile 1 patients at H24 (80% vs 19.4%, p=0.001). After adjustment on age and duration of CPB, sTREM-1 levels at H2 remained associated with ICU and hospital length of stay.","contentDiscussion":"","contentConclusion":"Early changes in sTREM-1 levels after cardiac surgery identified patients at high risk of post-operative complications and prolonged length of stay.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1216","session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BRAIK Rayan"},{"id":99540,"num":"A34642XT","reference":"FC-206","title":"Evaluation of balanced crystalloids on early renal recovery in patients with septic shock and continuous veno-venous hemofiltration: a retrospective observational study","formatedAuthors":"Xavier TETE (1), Romain GRIFFIER (2), Marie-Fleur PEARSON (2), David TRAN VAN (1)
(1) HIA Robert Picqué, Villenave D'ornon, FRANCE ; (2) CHU de Bordeaux, Bordeaux, FRANCE","contentIntroduction":"The impact on renal function of balanced crystalloids versus normal saline has been extensively studied in recent randomised trials (1). However, few data are available regarding their impact on renal recovery, particularly in patients admitted to the ICU and receiving extra renal replacement therapy on admission. The objective of our study was to evaluate the impact of balanced crystalloids versus normal saline on renal recovery in patients admitted in the ICU for septic shock complicated by acute renal failure requiring continuous hemofiltration.","contentPatientsMethods":"We conducted a single-center retrospective study included patients hospitalized in the intensive care unit between 2014 and 2019 who presented a septic shock with acute kidney injury requiring renal replacement therapy (RRT) within the first 48 hours. The patients included were classified into two groups according to their exposure to balanced crystalloids. The primary endpoint was early renal recovery defined as definitive weaning from RRT by day 7.","contentResultats":"Of the 91 patients included in the study, 38 were classified in the balanced crystalloid (BCs) group and 53 in the unbalanced crystalloid (UBCs) group. The median volume of balanced crystalloids administered during the first 7 days was 0ml (IQR [0;500]) in the UBCs group and 2000ml (IQR [1312.5;2500]) in the BCs group (p<0.001). The total volume of fluids administered was not statistically different between the BCs group and the UBCs group (p=0.67). On day 7, 47.4% of patients in the BCs group recovered versus 58.5% in the UBCs group (p=0.29). There was no difference after adjustment on confounding factors in multivariate analysis. The mean duration of RRT, maximum chloruraemia, and ICU mortality were not significantly different between the two groups. In multivariate analysis, a positive fluid balance lower than 5% of baseline weight was associated with better renal recovery (OR 0.35; [0.13; 0.9]).","contentDiscussion":"","contentConclusion":"Our study did not find a benefit to the use of balanced crystalloids on t renal recovery in our population of patients with septic shock complicated by AKI requiring early continuous hemofiltration. Further studies are needed to determine wether using balanced cristalloids improves renal recovery when renal replacement therapy is required.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":null,"session":"FLASH COM - Insuffisance rénale et troubles métaboliques","theme":"Uro-néphrologie métabolique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, et al. Balanced Crystalloids versus Saline in Critically Ill Adults. N Engl J Med. mars 2018;378(9):829?39","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TETE Xavier"},{"id":99541,"num":"A34331sb","reference":"FC-207","title":"Risk factors for mortality in anemic patients in the intensive care unit.","formatedAuthors":"Sabah BENHAMZA (1), Badreddine ATAK (1), Mohamed LAZRAQ (1), Abdelhak BENSAID (1), Youssef MILOUDI (1), Najib EL HARRAR (1)
(1) Hôpital 20 Août 1953, CHUIR , Casablanca, MAROC","contentIntroduction":"Anemia affects about two thirds of patients upon admission to the ICU (1), and may lead to transfusions which may cause complications. Our objective was to specify the risk factors of mortality of anemic patients in our department.","contentPatientsMethods":"Retrospective cohort over 1 year, in the intensive care unit of the 20 August hospital of Casablanca. All patients with anemia below 13g/dl for men and 12g/dl for women were included and excluded those coming from the hematology department or followed for a hematopathy.","contentResultats":"Out of 442 hospitalizations, 160 were included. The incidence of anemia was 36%. The mean age was 45 years, sex ratio M/F was 1.58. 26% were admitted for postoperative cephalic surgery and 12% for diabetic ketoacidosis. 82% of the patients were anemic on admission. Clinical signs were dominated by tachycardia (59%) and consciousness disorders in (41%). Ferritinemia was collapsed in 39%, the infectious workup was positive with CRP and PCT elevated in 72% and 78% of cases respectively. 49% were transfused with red blood cells. 73% stayed less than 7 days and 15% more than 14 days. At discharge, 40% of the patients exceeded the threshold of 13g/dl. 24% of our patients died. In multivariate analysis, the degree of anemia was not a risk factor for mortality, unlike SOFA score > 5 (OR 6.9 IC95% [2.7-17.4]) and blood transfusion which was a protective factor (OR=0.3 IC 95% [0.2-0.7]).","contentDiscussion":"","contentConclusion":"The degree of anemia was not associated with mortality in our study, contrary to the SOFA score, because it is probably the terrain and the causal pathology that cause death.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1- Zittoun J. Anémies macrocytaires carentielles. EMC 13-001-10 n.d.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MILOUDI Youssef"},{"id":99542,"num":"A34692ot","reference":"FC-208","title":"Thombotic microangiopathy in ICU : a retrospective study of 20 years","formatedAuthors":"Sana KHARRAT (1), Olfa TURKI (1), Kamilia CHTARA (1), Sabrine BRADAII (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) CHU Habib bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"Thrombotic microangiopathy (TMA) is a rare condition. It covers a group of related disorders characterized by thrombosis in the micro-vascularization and consequent organ dysfunction. It is responsible for significant morbidity and mortality. However, only a few reports have been published so far. The aim of the study was to describe our cohort of TMA in terms of incidence, clinico-biological presentation, management and outcome. We also aimed to identify factors associated with poor prognosis","contentPatientsMethods":"Our study was retrospective, conducted in an intensive care unit. The study period was 20 years: from January 1, 2001 to December 31, 2020. Our study included a descriptive part observing the different epidemiological, clinical, biological and evolutionary characteristics of patients admitted for TMA. The second part consisted on an analytical study highlighting the poor prognostic factors in our patients.","contentResultats":"A total of 37 patients were included. The incidence of TMA in the ICU was 0.18% with a female predominance and an average age of 34.8 years. Hemolytic anemia and thrombocytopenia were present in all patients.\n Neurological manifestations were the most frequent clinical signs (81.1%). Thrombotic thrombocytopenic purpura occupied ¾ of MAT ‘s forms in our cohort.TMA associated with pregnancy in 45.9% of cases . Medical support was based on plasma exchange (70.3%) in association with corticoids and immunoglobulins.\n Follow-up of the patient showed an exacerbation rate of 18.9% and complications such as infections in 45.9% of cases.\n Mortality rate was 29.7%. Factors correlated with poor prognosis in our cohort were age > 36 years, Glasgow score < 9 and platelet count < 14000 elts/mm3 on admission.","contentDiscussion":"","contentConclusion":"TMA is still a cause of high mortality. A better knowledge of this disease and the awareness of physicians as well as the development of diagnostic means could improve the prognosis.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TURKI Olfa"},{"id":99543,"num":"A34006FD","reference":"FC-209","title":"Impact of French lyophilized plasma transfusion in Trauma Center for severe civilian trauma patients.","formatedAuthors":"Flora DELAMAIRE (1), Thomas LEBOUVIER (1)
(1) CHU Rennes, Rennes, FRANCE","contentIntroduction":"The initial management of severe trauma patients with hemorrhagic shock requires early blood products transfusion. Administration of high plasma: Red Blood Cell (RBC) ratio is associated with a reduction in mortality. French Lyophilized Plasma (FLYP) as been used for years for military prehospital care.\n We hypothesized that the use of FLYP for civilian severe trauma patients would reduce time for first plasma administration, reduce number of RBC transfused before first plasma and achieve a plasma:RBC transfusion ratio greater than 1:2.","contentPatientsMethods":"This retrospective study was performed in a level 1 trauma center from January 2015 to June 2020. FLYP was available in trauma center since June 2017. Severe trauma patients who received massive transfusion (four RBC in the first hour and/or 10 RBC in the first 24h) were included and divided in 2 groups according to the period of inclusion: Fresh Frozen Plasma (FFP) group before June 2017 and FLYP group after.","contentResultats":"Twenty-eight severe trauma patients were included in the FLYP group and 12 in the FFP group. The time until the first transfusion of plasma was shorter in the FLYP group, 35 min (IQR 20, 45) vs. 59 min (IQR 36, 88) in the FFP group (p=0,007). The number of RBC transfused before the first plasma was lower in the FLYP group than in the FFP group, respectively 2 vs. 3,67 (p=0,002). The ratio plasma:RBC greater than 1:2 was obtained in 26 (93%) patients of the FLYP group vs 8 (67%) in the FFP group (p=0,05).","contentDiscussion":"","contentConclusion":"FLYP permitted an early transfusion of plasma during the massive transfusion of severe trauma patients. It significantly reduces time for in hospital plasma delivery and improved the order of blood products transfusion. It could permitted to obtain a greater than 1:2 plasma:RBC ratio in the trauma center. These results should be confirmed by a randomized trial.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DELAMAIRE Flora"},{"id":99544,"num":"A34510rb","reference":"FC-210","title":"Storage time of transfused packed red blood cells and mortality in crtically ill patients: a retrospective study.","formatedAuthors":"Rafla BEN DABEBISS (1), Jihène MAHMOUD (1), Salma CHOUCHÈNE (1), Hajer ZOUARI (1), Amina BOUATAY (1), Houssem HMOUDA (1)
(1) Sahloul University Hospital, Sousse, TUNISIE","contentIntroduction":"Anemia is frequently diagnosed in intensive care. It may be present at admission or may develop during ICU stay due to blood loss secondary to frequent blood sampling in most of the cases. Red blood cell (RBC) transfusions may be lifesaving in some circumstances. However, several studies have reported increased morbidity and mortality in transfused patients due to \"storage lesions\" of older blood. This study focuses on outcome of transfused patients according to storage time of RBCs, and compares transfusion yield between older and newer blood.","contentPatientsMethods":"This is a retrospective descriptive and analytical study of patients admitted between January 2014 and January 2021 who received RBC transfusion in the ICU. Epidemiological, clinical, and laboratory data were collected, as well as the number of transfused packed RBCs, storage time (age) of each unit, and estimation of blood spoliation secondary to blood sampling during ICU stay.","contentResultats":"During the study period, 80 patients were concerned by 150 transfusion episodes, including 236 packed RBCs. The mean age of patients was 57.1 ± 18,5 years. All patients had co-morbid conditions. Acute respiratory failure was the most frequent diagnosis present in 65% of cases at admission. The APACHE II score was 20.4 ± 9.4, and SAPS II score was 48.5 ± 21,1. The mean hemoglobin level at admission was 9 ± 2,7 g/dl. The mean pre-transfusion hemoglobin level was 6.9 ± 1.1 g/dl g/dL. The mean time to first ICU transfusion was 7.7 ± 8.7 days. Age of RBCs was 1 to 5 days in 21 transfusion episodes (14%), 6 to 10 days in 46 episodes (30.7%), 11 to 19 days in 59 episodes (39.3%), and ≥ 20 days in 24 transfusion episodes (16%). Mortality rate among transfused patients was 47.5%, and was related to severity of illness. Patients who received older blood did not have a significantly higher mortality (p=0,839), however the increment in hemoglobin per episode was significantly higher with newer blood (P=0.001). The mean value of blood spoliation was 426.7 ± 387.9 ml, and the number of transfusion episodes increased with blood spoliation and length of ICU stay. There was no statistically significant link between blood spoliation and mortality.","contentDiscussion":"","contentConclusion":"Newer transfused blood resulted in significantly higher hemoglobin increment. 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(1) CHU Sainte-Justine, Montreal, CANADA ; (2) Réanimation et Surveillance Continue Pédiatriques, Hôpital Jeanne de Flandre, CHRU Lille, Lille, Lille, FRANCE ; (3) Paediatric Intensivist and research lead for paediatric critical care, Department of Pediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, Oxford, ROYAUME-UNI ; (4) Paediatric Intensivist, Department of Pediatrics, Great Ormond Street Hospital, London, ROYAUME-UNI ; (5) Transfusion Medicine, Department: Haematology, NHS Blood & Transplant/Oxford Radcliffe Hospitals, Oxford, ROYAUME-UNI ; (6) Pediatric Critical Care, Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, The Montreal Children's Hospital, McGill University, Montreal, CANADA ; (7) Pediatric Intensive Care Unit, Tokyo Women's Medical University, Department of Intensive Care Medicine, Tokyo, JAPON ; (8) Pediatric intensive care unit, Department of Pediatrics, CHC Liège, Liège, BELGIQUE ; (9) Unité de recherches cliniques appliquées, Research Centre, CHU Sainte-Justine, Montreal, CANADA","contentIntroduction":"To determine what single value of physiological parameter threshold would guide the RBC transfusion practice of pediatric intensivists, in addition to hemoglobin (Hb) concentration.","contentPatientsMethods":"Scenario-based self-administered questionnaire e-mailed to pediatric intensivists in 2021. Five scenarios were considered: 1) a previously healthy 4-year-old boy mechanically-ventilated after a severe multiple traumas, 2) idem, but with a toxic shock syndrome and ARDS, 3) idem, but after ablation of hepatoblastoma; 4) 5-month-old boy admitted to PICU following corrective surgery for tetralogy of Fallot; 5) 3-week-old boy with hypoplastic left heart syndrome admitted to PICU after Norwood + Sano procedure. Patients were hemodynamically stable in all scenarios. Respondents addressed three questions:\n 1. What baseline Hb concentration would prompt you to prescribe an RBC transfusion in this scenario?\n 2. Do you use the physiologic parameter to guide your RBC transfusion practice?\n What threshold of the parameters would prompt you to give an RBC transfusion if Hb is 1 g/dL above the baseline Hb that you chose in 1st question?","contentResultats":"132 among 235 eligible respondents (56%) from France (50), United Kingdom (36), Canada (16), Japan (15) and Belgium (11) filled the questionnaire.\n The mean baseline Hb thresholds chosen are detailed in Table 1.\n Two out of 7 physiologic parameters (ScvO2 and blood lactate) were used by more than 75% of respondents to guide their RBC transfusion practice (Table 1). The proportion of respondents who stated that they do not use some parameters was higher in the trauma case (range: 21% to 75%); it was lower for the other scenarios (range: 0% to 39%). The difference in use between the 5 scenarios was statistically significant for all parameters (P","contentDiscussion":"","contentConclusion":"The proportion of respondents who do not use some parameters changed with different basic disease. Only ScvO2 and blood lactate were used by more than 75% of respondents to guide their RBC transfusion practice in PICU patients. Respondents seem to consider a ScvO2 threshold of 58% and blood lactate threshold of 4 mmol/L.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LACROIX Jacques"},{"id":99546,"num":"A34485JL","reference":"FC-212","title":"Survey on how dynamic physiologic markers can modulate the hemoglobin threshold and guide red blood cell (RBC) transfusion practice in pediatric intensive care units (PICU), on behalf of the CCCTG, PCCS, JICRG and GFRUP","formatedAuthors":"Anne GALLAND (1), Marisa TUCCI (1), Stéphane LETEURTRE (2), Avishay SARFATTI (3), Samiran RAY (4), Simon STANWORTH (5), Patricia FONTELA (6), Atsushi KAWAGUCHI (7), Pierre DEMARET (8), Thierry DUCRUET (9), Jacques LACROIX (1), Geneviève DU PONT-THIBODEAU (1)
(1) Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, CANADA ; (2) Réanimation et Surveillance Continue Pédiatriques, Hôpital Jeanne de Flandre, CHRU Lille, Lille, France, Lille, FRANCE ; (3) Department of Pediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, ROYAUME-UNI ; (4) Department of Pediatrics, Great Ormond Street Hospital, London, ROYAUME-UNI ; (5) Transfusion Medicine, Department: Haematology, NHS Blood & Transplant/Oxford Radcliffe Hospitals, Oxford, ROYAUME-UNI ; (6) Pediatric Critical Care, Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, The Montreal Children's Hospital, McGill University, Montreal, CANADA ; (7) Pediatric Intensive Care Unit, Tokyo Women's Medical University, Department of Intensive Care Medicine, Tokyo, JAPON ; (8) Pediatric intensive care unit, Department of Pediatrics, CHC Liège, Liège, BELGIQUE ; (9) Unité de recherches cliniques appliquées, Research Centre, CHU Sainte-Justine, Université de Montréal, Montréal, CANADA","contentIntroduction":"To determine if the trajectory (2 sequential measures) of dynamic physiologic parameters modulates the Hb threshold and guides the stated RBC transfusion practice of pediatric intensivists, in addition to hemoglobin (Hb) concentration.","contentPatientsMethods":"Scenario-based self-administered questionnaire e-mailed to pediatric intensivists in 2021. There were five scenarios: 1) previously healthy 4-year-old boy mechanically-ventilated after a severe multiple trauma; 2) idem with toxic shock syndrome and ARDS; 3) idem after ablation of hepatoblastoma; 4) 5-month-old boy admitted to PICU following corrective surgery for tetralogy of Fallot; 5) 3-week-old boy with hypoplastic left heart syndrome admitted to PICU after a Norwood + Sano procedure. Respondents addressed two questions:\n 1. What Hb concentration would prompt you to prescribe an RBC transfusion to the patient in the scenario?\n 2. What would be the lowest acceptable Hb value that would prompt you to transfuse the patients described in the scenario given the Hb concentration that you chose (question #1) and the sequential results of the following physiologic parameters?","contentResultats":"132 participants among 235 eligible respondents (56%) from France (50), United Kingdom (36), Canada (16), Japan (15) and Belgium (11) filled the questionnaire.\n Mean and median baseline Hb threshold are reported in Table 1.\n Two parameters (ScvO2 and blood lactate) improved over time: the Hb threshold decrease was small in five scenarios for blood lactate and three scenarios for ScvO2 (range: -0.2±0.1 to 0.1±0.9 g/dL), but it reached -0.4±1.1 and -0.6±0.7 g/dL for blood lactate in two cardiac scenarios. We did not find a statistically significant difference between scenarios for blood lactate (p=0.87), but the difference was significant when ScvO2 increases from 50% to 70% (p0.05 between scenarios). However, the mean Hb threshold increased by ≥1g/dL after ScvO2 dropped from 70% to 50% (p","contentDiscussion":"","contentConclusion":"Improvement of ScvO2 or blood lactate did not prompt pediatric intensivists to decrease significantly their Hb threshold (?","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LACROIX Jacques"},{"id":99547,"num":"A34507bb","reference":"FC-213","title":"Thrombocytopenia and covid19: what pronostic value?","formatedAuthors":"Bouthaina BOUCHECH (1), Oumaima BEN AMOR (2), Ameni CHTOUROU (2), Hichem KOLSI (2), Salma KTATA (1), Mariem KESKES (1), Bilel LOUATI (2), Abdelhamid KAROUI (1,2)
(1) hopital hbib bourguiba, Sfax, TUNISIE ; (2) hopital de campagne Slim Chaker, Sfax, TUNISIE","contentIntroduction":"Since December 2019, a severe acute respiratory syndrome coronavirus 2 is spreading rapidly around the world and become a pandemic. Among the confirmed cases, 15% develop severe forms and the mortality in intensive care is 30 to 70% .Indicators are needed to evaluate and predict the severity of the disease.\n We aimed to see whether thrombocytopenia is independently associeded to poor outcome in critically patients with COVID-19.","contentPatientsMethods":"This is a retrospective study extended over a period from February to July 2021 including 240 infected patients by SARS-COV-2.\n The exclusion criteria for this study are patients with progressive hematological pathology, patients with chronic renal failure and patients on anticoagulation or antiplatelet therapy before their infection with SARS-CoV-2. Biological monitoring of platelet levels is carried out in all patients admitted to intensive care on day1, Day5, Day12 and beyond 12 days every 72 hours. All these patients had a preventive or curative anticoagulation according to the context by LMWH. Thrombocytopenia is defined by platelet count <150 x 109/L\n For each patient, the nadir platelet count was identified and categorized into 3 groups : G1 [150-100]; G2 [100-50] and G3 [<50] after taking the unit (× 109/L) away from the report of nadir platelet count.","contentResultats":"A total of 240 patients are included in this study, 60.7% of whom are male. The median age is 62.4 years\n The diagnosis of the infection is made in 37% by a rapid test, 25.4% by RT-PCR and 82.6% by chest CT.\n 94% of patients have a enoxaparin anticoagulation, 44.2% of whom had curative anticoagulation during their stay.\n We found that 26.7% have thrombocytopenia and for patients categorized into [150-100]; [100-50] and [<50] groups, the thrombocytopenia is 5.1%, 12.3%, and 7.2% respectively.\n Patients develop thrombocytopenia between D1 and D27 with an average of 9.9 days (11%) .patients with thrombocytopenia died with significant difference (p=0.3%). The G2 presents a statistically significant difference with (P =0.07%) in terms of death as well as the early onset of thrombocytopenia (p=0.065).","contentDiscussion":"","contentConclusion":"Although, it 's a retrospective descriptive study and the tests on platelet count for each patient had different time intervals in between .This study confirms that thrombocytopenia upon admission is a strongly associated to poor outcome and mortality in patients hospitalized for SARS-CoV-2 pneumonia, independently from other markers of severity.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1217","session":"FLASH COM - Cytopénies et transfusion","theme":"Hématologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUCHECH Bouthaina"},{"id":99548,"num":"A34555CB","reference":"FC-214","title":"Respiratory variations of Central Venous Pressure during a standardized inspiration maneuver to predict fluid responsiveness in spontaneously breathing patients: a prospective, monocentric, diagnostic test evaluation","formatedAuthors":"Claire BOUREL (1), Arthur DURAND (1), Benoit TERSCHIPHORST (1), Thierry ONIMUS (1), Raphael FAVORY (1), Sebastien PREAU (1)
(1) CHU de Lille, Lille, FRANCE","contentIntroduction":"Delayed or excessive volume expansion increases morbidity/mortality in acute circulatory failure patients. Therefore, prediction and assessment of fluid responsiveness (FR) is necessary. Hemodynamic parameters used to guide fluid therapy are regularly limited by spontaneous breathing (SB) or technicity. Central Venous Pressure (CVP) as a static parameter fails to accurately predict FR. The ideal marker to predict FR has to be accessible, fast, usable in spontaneous breathing and accurate. CVP respiratory variations (CVPv) could meet these criteria. We analyzed the accuracy of CVPv to predict FR in spontaneously breathing patients, and its optimization by a standardized inspiratory maneuver (SIM).","contentPatientsMethods":"We carried out a monocentric, prospective, diagnostic test evaluation. Patients admitted to our intensive care units that were spontaneously breathing and had a central venous catheter were prospectively included. CVPv was measured while the patient was spontaneously breathing, with (CVPv-sim) and without SIM (CVPv-nsim), before and after a passive leg raising test (PLR). The SIM was validated by a buccal cavity pressure <-3mmH2O. CVPv accuracy to predict FR was evaluated. FR was defined as a PLR-induced increase in the velocity time integral of aortic blood flow during a passive leg raising maneuver (self-fluid challenge) ≥10%.","contentResultats":"Among 63 patients, 38 (60%) presented FR. CVPv-nsim was not significantly different between fluid responsive and fluid unresponsive patients (-4.9mmHg [-7.5;-3.1] vs. -4.1mmHg [-5.4;-2.8], respectively; p=0.15). CVPv-sim was higher in fluid responsive than fluid unresponsive patients (-3.6mmHg [-10.6 ; -1.6] vs -9.7mmHg [-13.9 ; -6.2], respectively; p<0.05). CVPv-sim <-4,5 mmHg predicted FR with a sensitivity of 89%, a specificity of 56%, and an area under ROC curve of 0.72 [0.56;0.86]. There were 4 false negative and 11 false positive patients. \n The overall median CVPv-sim increased from -8.6mmHg [-12.5;-3.6] to -4.1mmHg [-9.75;-0.25] during PLR (p<0.05). Among the 11 false positive results before PLR, 4 patients could not be analyzed during PLR, 4 patients moved from false positive to true negative and 3 increased their CVPv-sim but remained false positive during PLR.","contentDiscussion":"","contentConclusion":"In presence of a central venous catheter, CVPv may be useful to identify spontaneously breathing patients unresponsive to volume expansion.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUREL Claire"},{"id":99549,"num":"A34619GW","reference":"FC-215","title":"Prediction of fluid responsiveness by the corrected carotid flow time changes during a passive leg rising maneuver","formatedAuthors":"Guilhem WATTECAMPS (1), Mickaël MORICONI (1), Alexandre TONNELIER (1)
(1) CHIC Quimper, Quimper, FRANCE","contentIntroduction":"The physician must rely on trustworthy and reliable tools to predict fluid responsiveness in order to provide an efficient and safe fluid expansion. We aimed to evaluate the ability of the measurement of corrected carotid flow time changes during a passive leg rising maneuver to predict fluid responsiveness among intensive care unit patients.","contentPatientsMethods":"We performed a prospective and non-interventional study among patients in whom the physician in charge has decided a fluid expansion prior to the inclusion in the study. We performed the carotid flow time measurements before and after a passive leg rising maneuver. We used a linear Doppler probe. Fluid responsiveness was defined as an at least 15% rise in cardiac output following a fluid expansion of 500mL of isotonic saline solution. Cardiac output was assessed after the PLR maneuver, thanks to a transpulmonay thermodillution PICCO2® device. A second blinded investigator read the images recorded by the first one. We evaluated the accuracy of the cCFT changes through a ROC analysis. We evaluated the inter observers agreement with a Bland Altman analysis","contentResultats":"From January to july 2021, we included 21 patients, 13 responders and 8 non responders. The ROC analysis showed that a 4, 3% rise in cCFT predicted fluid responsiveness with a 76,9% sensitivity, an 87,5% specificity, a positive predictive value of 90,9% and a negative predictive value of 70%. The area under the curve was 0, 85 ; CI95% [0,68 ; 1]. In the post hoc blinded assessment, we showed a poor agreement between the two operators","contentDiscussion":"","contentConclusion":"Correct Carotid Flow Time changes during a PLR maneuver may be a good tool to predict fluid responsiveness. However the agreement between two observers is not so good and could be an obstacle to its widespread use.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"WATTECAMPS Guilhem"},{"id":99550,"num":"A34544DA","reference":"FC-216","title":"Acute circulatory failure: comparative study between a population with echocardiography and a population without echocardiography in the emergency department of oran university hospital.","formatedAuthors":"Djamel ALACHAHER (1), Mourad GOULMANE (1), Sofiane OUALI DADA (1), Nabil SIDI AISSA (1), Nabil TABET AOUL (1)
(1) Centre hospitalo-universitaire d'Oran/ Faculté de Médecine d'Oran . Université Oran 1 Ahmed Ben Bella , Oran, ALGERIE","contentIntroduction":"The shocks represent a frequent reason for hospitalization in the emergency department of the University hospital of Oran (CHUO), they are considered as serious states because in the absence of an adapted treatment, they can be life-threatening in the immediate.\n The main objective of our study is to assess the contribution of echocardiography in our patients admitted in shock from a diagnostic, therapeutic and prognostic perspective","contentPatientsMethods":"A clinical and epidemiological, descriptive, prospective and mono-centric study made in the reception unit of the medical emergency department of the CHU Oran concerning any patient aged over 15 years admitted for a no traumatic shock.\n The group of patients benefiting from TTE evaluated during a period of two years from 01-01-2016 to 31-12-2017 and designated the “echo yes” group was compared with a second group of patients who did not benefit from the ETT collected from 01-01-2015 to 31-12-2015 and named group \"echo no\".","contentResultats":"seventy-seven (77) patients from the general population (n = 156) presenting a shock collected in our study benefited from TTE, i.e. a frequency of 49.35% with an average age of 64, 40 ± 17.70 years [17-106] and a sex ratio of 1.13, comorbidities are dominated by hypertension (59.70%) and diabetes (39%) and the reasons for consultation are represented by deterioration in general condition (74.30%) and disturbance of consciousness (50.64%). The ETT by two-dimensional exploration and Doppler allowed to determine the etiological mechanism in 94.8% of cases [38.96% (n = 30) hypovolemic shock, 36.36% (n = 28) cardiogenic shock, 16, 88% (n = 13) septic shock and 2, 59 %(n=2) Anaphylactic shock]. The rate of cases of undetermined mechanism decreased very significantly (“echo yes”: 5.20% vs. “echo no”: 36.70%), decrease by more than 31%, p <0.001. The correction of the initial diagnostic hypothesis was noted in 29/77 patients, ie a frequency of 37.66%.","contentDiscussion":"","contentConclusion":"Our work has clearly illustrated and shown the contribution of TTE in improving the overall care of patients in shock by modifying the initial diagnostic hypothesis with, as corollary to the therapeutic management, to specify the etiological mechanism and to improve the prognosis of the patients","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALACHAHER Djamel"},{"id":99551,"num":"A34517BE","reference":"FC-217","title":"Assessment of right ventricular mechanics by 3D transoesophageal echocardiography in the early phase of ARDS","formatedAuthors":"Bruno EVRARD (1), Bálint Károly LAKATOS (2), Marine GOUDELIN (1), Philippe VIGNON (1), Attila KOVÁCS (2)
(1) CHU Limoges, Limoges, FRANCE ; (2) Heart and Cardiovascular Center, Semmelweis University, Budapest, HONGRIE","contentIntroduction":"There are growing evidence distinguishing SARS-CoV-2-induced Acute Respiratory Distress Syndrome (ARDS) and ARDS of other causes. This raises the possibility that severe COVID-19 may result in specific alterations of Right Ventricular (RV) mechanics. The objective was to compare global and axial right ventricular ejection fraction in ventilated patients for moderate-to-severe acute respiratory distress syndrome (ARDS) secondary to early SARS-CoV-2 pneumonia or to other causes, and in ventilated patients without ARDS used as reference.","contentPatientsMethods":"Retrospective single-center cross-sectional study including 64 ventilated patients: 21 with ARDS related to SARS-CoV-2 (group 1), 22 with ARDS unrelated to SARS-CoV-2 (group 2), and 21 without ARDS (control group). Real-time three-dimensional transesophageal echocardiography was performed for hemodynamic assessment within 24 hours after admission. Contraction pattern of the right ventricle was decomposed along the three anatomically relevant axes. Relative contribution of each spatial axis was evaluated by calculating ejection fraction along each axis divided by the global right ventricular ejection fraction.","contentResultats":"Global right ventricular ejection fraction was significantly lower in group 2 than in both group 1 and controls (median: 43% [25th-75th percentiles: 40-57] vs. 58% [55-62] and 65% [56-68], respectively: p<0.001). Longitudinal shortening had a similar relative contribution to global right ventricular ejection fraction in all groups (group 1: 32% [28-39], group 2: 29% [24-40], control group: 31% [28-38], p=0.6). Radial shortening was lower in group 2 when compared to both group 1 and controls (45% [40-53] vs. 57% [51-62] and 56% [50-60] respectively: p=0.005). The relative contribution of right ventricular shortening along the anteroposterior axis was not statistically different between groups (group 1: 51% [41-55], group 2: 56% [46-63], control group; 56% [50-64], p=0.076).","contentDiscussion":"","contentConclusion":"During early hemodynamic assessment, the right ventricular systolic function appears more impaired in ARDS unrelated to SARS-CoV-2 when compared to early stage SARS-CoV-2 ARDS. Radial shortening appears more involved than longitudinal and anteroposterior shortening in patients with ARDS unrelated to SARS-CoV-2 and decreased right ventricular ejection fraction.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"VIGNON Philippe"},{"id":99552,"num":"A34617GG","reference":"FC-218","title":"Visualization of the superior vena cava using trans-thoracic echocardiography: learning curves using the cusum method","formatedAuthors":"Joséphine SOLTANI (1), Matthieu PETIT (1,2), Mathieu GODEMENT (1), Edouard JULLIEN (1,2), Antoine VIEILLARD-BARON (1,2), Cyril CHARRON (1), Guillaume GERI (1)
(1) Hôpital Ambroise Paré, Boulogne Billancourt, FRANCE ; (2) Université Paris Saclay, Saclay, FRANCE","contentIntroduction":"Echocardiography is routinely used in the hemodynamic monitoring of ICU patients. Trans-esophageal echo (TEE) has been described to provide additional evaluation, especially on the superior vena cava (SVC). While trans-thoracic echo (TTE) remains a marginal tool in SVC evaluation, learning curve of such a skill is unknown.","contentPatientsMethods":"Monocentric observational study performed in a tertiary medical ICU used to use TEE in hemodynamic monitoring. A theoretical training was provided to all the medical staff (i.e. the trainees) and a structured data collection was performed including history of echo training of each trainee as well as echo data (including 2-dimensional [2D] and time-movements [TM] screenshots). These screenshots were reviewed by an external blinded expert using a Likert-derived scale (0 : incorrect, 1 : not optimal and 2 : correct) for 2D and TM views. The cumulative sum (CUSUM) method was used to evaluate the evolution of trainees’ skills over time ; an unacceptable failure rate (h1) and acceptable failure rate (h0) were a priori determined as 50 and 20 %, respectively. Trainees who crossed h0 were considered successful while those crossing h1 had a unacceptable failure rate. Comparison of characteristics of trainees who succeeded and who failed were compared.","contentResultats":"13 trainees were observed for a 2-months period. The median success rate was 77.8 [65.2, 80] and 33.3 [23.8, 42.9] for obtaining a correct 2D and a TM view, respectively. Three trainees crossed h0 for getting a correct 2D view while none did for a correct TM view. Crossing h0 occurred after 5, 12 and 17 procedures. Furthermore, all the trainees crossed h1 for the TM view, meaning the whole group crossed an unacceptable failure rate for this endpoint (Figure). The comparison of trainees who succeeded and who failed did not reveal any difference.","contentDiscussion":"","contentConclusion":"A one-shot theoretical training to get a correct vizualisation of the superior vena cava using TTE was not enough as most of them did not reach an acceptable failure rate.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SOLTANI Joséphine"},{"id":99553,"num":"A34403YC","reference":"FC-219","title":"CARDIAC MANIFESTATION IN ADULT HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS: CLINICAL AND ECHOCARDIOGRAPHIC STUDY","formatedAuthors":"Yohan CERVEAUX (1), Michel SLAMA (2), Julien MAIZEL (2), Clément BRAULT (2)
(1) Centre hospitalier ouest Réunion, Saint Paul, REUNION ; (2) Centre hospitalo-universitaire Amiens Picardie, Amiens, FRANCE","contentIntroduction":"Only a few cases of cardiac dysfunction in hemophagocytic lymphohistiocytosis (HLH) have been reported.\n However, the prognosis for these patients is poor. A complete echocardiographic evaluation may provide an important clue for a better understanding of the pathogenesis.","contentPatientsMethods":"We conducted a retrospective study of all patients diagnosed with HLH and hospitalized in intensive care unit (ICU) between 2008 and 2020. All patients had to get a baseline echocardiography in the 2 years before ICU admission. We compared SALH cases versus patients with septic shock.","contentResultats":"We included 28 patients; all of them had haematological malignancies. Compared with baseline echocardiography, left ventricular ejection fraction (LVEF) was decreased during SALH (55% vs. 65%; p=0.02), with no significant difference in cardiac output. Likewise, the right ventricle function, assessed by tricuspid annular plane systolic excursion (TAPSE), was significantly impaired (p <0.01). Only 36% of SALH patients had a LVEF lower than 50% versus 63% of septic shock patients (p=0.03).\n ?","contentDiscussion":"","contentConclusion":"Cardiac involvement in HLH patients is characterized by a left and right ventricular dysfunction, however, it is less frequent and severe than in septic cardiomyopathy. Cardiac involvement in HLH and in septic shock could share similar physiopathological mechanisms or it might be the same clinical affection. A prospective study comparing septic myocarditis and HLH heart disease is needed to conclude.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"CERVEAUX Yohan"},{"id":99554,"num":"A34615HK","reference":"FC-220","title":"How central venous oxygen saturation can be used as a prognostic tool in cardiac surgery?","formatedAuthors":"Hichem KOLSI (1), Wael JAWADI (1), Mariem KESKES (1), Bouthaina SELLAMI (1), Salma KETATA (1), Salim AMOURI (1), Rahma DERBEL (1), Hichem CHEIKHROUHOU (1), Zied TRIKI (1)
(1) Centre hospitalo-universitaire Habib Bourguiba, Sfax, Sfax, TUNISIE","contentIntroduction":"Cardiac surgery with cardiopulmonary bypass (CPB) is now known to be a life saving procedure. Nevertheless, CPB induces systemic inflammatory response and oxygenation impairment. Central venous oxygen saturation (ScvO2) is a classic marker of dysoxia. Low and high ScvO2 are associated with adverse outcome. But, there are no studies defining clearly abnormal values of ScvO2 and assessing the prognostic interest of ScvO2 in cardiac surgery. The aim of this study was to investigate about the impact of increasing and decreasing values of ScvO2 on mortality and morbidity after cardiac surgery, and to define optimal thresholds of high and low ScvO2 to predict complications.","contentPatientsMethods":"This is a prospective, observational, monocentric clinical study.\n We included 156 patients over 18 years undergoing cardiac surgery with CPB from September 2018 to January 2020.\n We have excluded patients who have died during surgery, patients who can only leave the operating room with a circulatory assistance technique and patients with misplacement of central venous catheter (CVC).\n Venous blood gas was collected from middle line of CVC.\n Population was divided into 2 groups: group H with ScvO2 > 75% and group L with ScvO2 ≤ 75%. In group H, we analyzed receiving operating curve (ROC) of ScvO2 for occurring of postoperative complications. In group L, we analyzed ROC of - ScvO2 for occurring of postoperative complications. We tested then the correlation of the variables with prognosis interest to ScvO2 by Spearman test.","contentResultats":"Median age was 62 (53; 68). Complications rate was 37.8%. Mortality rate was 18.6%.\n In group H, we have found that ScvO2 predicts complications with area under ROC 0.776. The best threshold was 80.6%. Moreover, we found that ScvO2 is significantly correlated with CPB time, mechanic ventilation time and majority of postoperative prognosis scores.\n In group L, the area under ROC of - ScvO2 concerning complications was 0.774. The best threshold was 69.7%. We found a significant negative correlation of ScvO2 to CPB time, mechanic ventilation time and majority of postoperative prognosis scores.","contentDiscussion":"","contentConclusion":"We conclude that both low and high ScvO2 are associated with adverse outcome after cardiac surgery. For patients with supranormal or low ScvO2, we should use additional hemodynamic monitoring to facilitate adequate therapy in the postoperative course.\n But, to allow ScvO2 to be placed as a target for postoperative resuscitation algorithm, a randomized trial comparing a conventional resuscitation strategy with a strategy based on defined levels of ScvO2 is essential.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1218","session":"FLASH COM - Outils diagnostics et pronostric au cours des états de choc","theme":"Hémodynamique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"KOLSI Hichem"},{"id":99555,"num":"A34499JQ","reference":"FC-221","title":"Inappropriate intensive care unit stays: Perception and experience of ICU caregivers","formatedAuthors":"Lucas MATHEY (1), Marine JACQUIER (1,2), Nicolas MEUNIER-BEILLARD (3,4), Fiona ECARNOT (5), Pascal ANDREU (1), Jean-Baptiste ROUDAUT (1), Marie LABRUYERE (1,3), Jean-Philippe RIGAUD (6,7), Jean-Pierre QUENOT (1,2,3,8)
(1) CHU Dijon, Dijon, FRANCE ; (2) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (3) INSERM, CIC 1432, Module Épidémiologie Clinique, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (4) DRCI, USMR, CHU Dijon Bourgogne, Dijon, FRANCE ; (5) EA3920, Department of Cardiology, University Hospital Besancon, Besancon, FRANCE ; (6) Centre Hospitalier de Dieppe - Department of Intensive Care, Dieppe, FRANCE ; (7) Espace de Réflexion Éthique de Normandie, University Hospital Caen, Caen, FRANCE ; (8) Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Dijon, FRANCE","contentIntroduction":"The question of futile or disproportionate care in the intensive care unit (ICU) has long been a subject of debate. It can happen that ICU stays come to be deemed inappropriate, after the fact, even by the ICU physicians themselves 1. This study aimed to describe and understand the perceptions of ICU caregivers about ICU stays that the ICU physicians themselves judge to be inappropriate.","contentPatientsMethods":"We performed a qualitative study using semi-structured interviews with caregivers from 3 ICUs in the region of Burgundy-Franche-Comté. An interview guide was developed in advance and focused on 3 questions, namely: (1) what is your experience and perception of ICU stays that are judged after the fact to have been inappropriate? (2) What are the consequences of an inappropriate ICU stay, in your experience? (3) In your view, how could such stays be avoided? Interviews were recorded, transcribed in full and analysed (in French) using thematic analysis. Participants were interviewed until saturation was reached.","contentResultats":"A total of 17 nurses and 4 nurses’ aides were interviewed. Age, medical history, poor general status, deteriorating quality of life, and the lack of clear healthcare goals were the main criteria cited by respondents as possible reasons why an ICU stay would be deemed inappropriate after the fact by ICU physicians. The respondents also reported that certain specific circumstances may also give rise to ICU stays that could be inappropriate, e.g. emergency clinical situations, lack of knowledge about case, availability and/or choice of physicians, pressure from the patient’s family or from other physicians to admit the patient, and refusal of death. Possible consequences of inappropriate ICU stays cited by our respondents included stress, anxiety, a feeling of incomprehension and inequality, deprivation of liberty, and loss of the feeling that their work is meaningful. Conversely, possible avenues to preventing inappropriate ICU stays cited by the respondents included anticipation of acute care needs, and careful evaluation of the patient prior to admission.","contentDiscussion":"","contentConclusion":"In daily practice, paramedical caregivers understand how some ICU stays may come to be considered after the fact as having been inappropriate. They could undoubtedly provide valuable input into admission decisions, to avoid inappropriate ICU stays and to ensure equitable distribution of healthcare resources and the respect of patients’ wishes.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1219","session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Quenot JP, Large A, Meunier-Beillard N, et al. 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(1) CHU Dijon, Service de Médecine Intensive & Réanimation, Dijon, FRANCE ; (2) INSERM, CIC 1432, Module Epidémiologie Clinique, Dijon, France; CHU Dijon-Bourgogne, Centre d’Investigation Clinique, Module Epidémiologie Clinique/Essais Cliniques, Dijon, FRANCE ; (3) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (4) Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Dijon, FRANCE ; (5) DRCI, USMR, CHU Dijon Bourgogne, Dijon, FRANCE ; (6) EA3920, Department of Cardiology, University Hospital Besancon, Besancon, FRANCE ; (7) Centre Hospitalier de Dieppe, Department of Intensive Care, Dieppe, FRANCE ; (8) Espace de Réflexion Éthique de Normandie, University Hospital Caen, Caen, FRANCE","contentIntroduction":"Although the question of futile or disproportionate care in the intensive care unit (ICU) has been widely discussed in the literature, there is a paucity of studies about non-beneficial admissions to the ICU 1. Labelling ICU stays as non-beneficial may give a false perception of the utility of ICU management. Using a national survey of practices, we sought to define criteria for non-beneficial admissions to ICU, the circumstances in which they occur, and the possible consequences, with a view to identifying aspects that could be targeted for change.","contentPatientsMethods":"An online survey was made available from 22 June to 4 October 2021 via the LimeSurvey platform for ICU physicians. For each question, the physician was asked to answer on a 5-point Likert scale (strongly disagree/disagree/neutral/agree/strongly agree). The survey used the Network for Research in Ethics in Critical Care to ensure representativeness of the participating ICUs and forms of practice of the respondents.","contentResultats":"In total, 154/164 ICU physicians contacted (94%) completed the online survey. The main results highlight that an ICU admission must take account of the expected survival and quality of life after discharge, in view of the current clinical status and prior medical history of the patient. The urgency of the clinical situation, a lack of knowledge of the medical file, and a failure to anticipate potential ICU requirement in the patient’s healthcare trajectory are all factors that may lead to non-beneficial ICU admission. Stress, anxiety, incomprehension and even conflict with the patient’s family or between healthcare providers are possible consequences of ICU admissions occurring in such circumstances. Finally, one of the key measures that could be implemented to reduce or avoid non-beneficial admissions is pluridisciplinary meetings prior to ICU, involving the patient, the family, referring and treating physicians, as well as an ICU physician when the possibility of ICU admission is part of the patient’s healthcare goals.","contentDiscussion":"","contentConclusion":"This survey of practice suggests that there is a compelling need for shared reflection and decision-making, likely with greater involvement of ICU physicians, prior to ICU admission. This would take closer account of the preoccupations of non-ICU physicians, and could help to identify in advance the patients likely to benefit from ICU care, in coherence with their healthcare goals.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1219","session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Quenot JP, Large A, Meunier-Beillard N, PlosOne 2019 Sep 6;14(9):e0222039","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GRANGÉ Clotilde"},{"id":99557,"num":"A34343Vd","reference":"FC-223","title":"How is the COVID crisis a challenge for caregivers regarding the place of relatives in intensive care unit ?","formatedAuthors":"Valentin DE VILLIERS DE LA NOUE (1,2), Marcel-Louis VIALLARD (1)
(1) Université de Paris, Paris, FRANCE ; (2) CHU Robert Debré, Reims, FRANCE","contentIntroduction":"Intensive care unit is a technical environment in which patients' lives are at stake. The COVID pandemic has led to a restriction of the place given to the entourage of patients hospitalized in the intensive care unit. How is the COVID crisis a challenge for caregivers in terms of the place of the family and friends in the ICU?","contentPatientsMethods":"Qualitative study including 10 semi-directive interviews with caregivers working in the ICU.","contentResultats":"The COVID crisis disrupted the place of patients’ relatives in ICU. This inclusion had been established by various means before the crisis: 24-hour visits, participation to the mortuary toilet, pets’ visits, logbook, family lounges, presence of volunteers. These means lead to a better inclusion of relatives in ICU, even if there were still difficulties in the relationship with the family and friends : management of the acute phase, difficulties in communicating with the family and friends, waiting for care, choice of the person of trust, non-opening 24 hours a day. The COVID crisis added barriers : initial closure of all the services in which the caregivers interviewed worked, then partial reopening, fear of the virus, constraints related to equipment, exacerbated communication difficulties, lack of medical time. The caregivers tried to implement new means to include relatives in this context: videoconferencing, virtual logbook, more regular telephone interviews. These difficulties in making room for the family and friends have deteriorated the relationship with the relatives, and the caregivers’ experience regarding these changes is mostly negative.","contentDiscussion":"","contentConclusion":"COVID crisis was a challenge for caregivers to make room for the entourage of hospitalized patients. Despite the means implemented to maintain this link between caregivers and family members, the face-to-face relationship seems to be necessary for caregivers and family members to live serenely in the resuscitation context.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":null,"session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DE VILLIERS DE LA NOUE Valentin"},{"id":99558,"num":"A34353AA","reference":"FC-224","title":"Withholding or withdrawing therapy in intensive care unit: an analysis of collaboration among intensivist and general practitioner.","formatedAuthors":"Jean-Baptiste ETCHEVERRY (1), Céline RAVRY (1), Pierre GODARD (1,2), Thierry MAYET (1), Adrien AUVET (1)
(1) CH de Dax, Dax, FRANCE ; (2) CHU Bordeaux, Bordeaux, FRANCE","contentIntroduction":"French law and practice guidelines (1) impose collegial procedures and interdisciplinary collaboration in end-of-life decision making. This procedure involves the intensive care unit (ICU) team and an external consultant. General practitioner (GP) could be a relevant consultant, through his understanding of the patient history and his relation with the family. The purpose of this study was to explore GP and intensivist point of views regarding the GP involvement in the collegial decision of withholding or withdrawing therapy.","contentPatientsMethods":"We conducted a retrospective observational study over the year 2020. An online survey was sent by e-mail to the GPs and the intensivists of the 4 ICUs of a French mainland regional administrative county (“department”).","contentResultats":"132 GPs and 22 intensivists answered. Almost all of the GPs (118/132 ; 89%) had at least 1 patient in ICU over the year. (55/118 ; 47%) have been aware that end-of-life decision making concerned at least one of their patients. When such a process started, intensivists requested (26/55 ; 47%) of them to participate in the procedure by. Intensivists requested an external consultant in 77% situations. Most of the time, they asked a specialist (91%) and rarely discussed with the GP (36%). 61% of GPs felt having a strong impact on the procedure, whereas 46% of intensivists considered GP impact this way. 71% of GPs felt involved by the ICU team in the collegial decision, whereas 37% of intensivists felt the same way about it. Those professionals acknowledge a similar GP influence regarding the patient management (38% GP, 40% intensivists). 85% of GPs would like to be more solicited, whereas 36% of intensivists gave a major place to GP interventions. 79% of GPs were requested by a family member to help them understand the situation.","contentDiscussion":"","contentConclusion":"Our study shows that intensivists involved the GPs partially in the collegial decision. This lack of participation seems to be in inadequacy with GPs wish. A systematic involvement of the GP in the decision making of withholding or withdrawing treatment could be beneficial and could improve interaction with the family. 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(1) CHU Dijon, Dijon, FRANCE ; (2) Centre de recherche INSERM UMR1231 et LabEx LipSTIC, Université de Bourgogne-Franche Comté, Dijon, FRANCE ; (3) INSERM, CIC 1432, Module Épidémiologie Clinique, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (4) EA3920, Department of Cardiology, University Hospital Besancon, Besancon, FRANCE ; (5) Department of Intensive Care, Centre Hospitalier de Dieppe, Dieppe, FRANCE ; (6) Espace de Réflexion Éthique de Normandie, University Hospital Caen, Caen, FRANCE ; (7) Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Dijon, FRANCE ; (8) DRCI, USMR, CHU Dijon Bourgogne, Dijon, FRANCE","contentIntroduction":"Almost 70% of patients who are admitted to the intensive care unit (ICU) suffer from at least one chronic disease (1). Chronic disease in ICU patients is an additional risk factor for death and is associated with significant post-ICU disability. This study aimed to explore reflections and perceptions of non-ICU physicians about the anticipation of need for ICU admission in case of acute decompensation in patients with chronic disease.","contentPatientsMethods":"We performed a qualitative multicentre study using semi-structured interviews among non-ICU specialist physicians. The interview guide, developed in advance, focused on 3 questions: (1) What is your perception of ICU care? (2) How do you think advance directives can be integrated into the patient’s healthcare goals? and (3) How can the possibility of a need for ICU admission be integrated into the patient’s healthcare goals? Interviews were recorded, transcribed and analysed by thematic analysis. Interviews were performed until theoretical saturation was reached.","contentResultats":"In total, 16 physicians (8 women, 8 men) were interviewed. The main themes related to intensive care being viewed as a distinct specialty, dispensing very technical care, and with major human and ethical challenges, especially regarding end-of-life issues. The participants also mentioned the difficulty in anticipating an acute decompensation, and the choices that might have to be made in such a situation, for patient that they have known and followed for a long time. The timing of discussions about potential decompensation of the patient, the medical culture and the presence of advance directives are issues that arise when attempting to anticipate the question of ICU admission in the patient’s healthcare goals or wishes. To facilitate this process, it was proposed that dedicated consultations bringing together the patient’s referring physicians and ICU physicians could help to raise awareness and knowledge about ICU, and promote a palliative culture.","contentDiscussion":"","contentConclusion":"This study highlights the difficulties encountered by treating physicians of anticipating potential acute decompensation with ICU requirement in patients with chronic disease. It also opens perspectives for actions that could promote a pluridisciplinary approach to anticipating acute decompensation and ICU requirements in patients with chronic disease.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1219","session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Quenot JP, Helms J, Labro G, et al. Ann Intensive Care 2020;10:20","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"TAHA Alicia"},{"id":99560,"num":"A34505JQ","reference":"FC-226","title":"Anticipating need for intensive care unit admission in a patient’s healthcare trajectory: A qualitative study among general practitioners","formatedAuthors":"Marine JACQUIER (1,2), Bérénice FOUQUET (3), Nicolas MEUNIER-BEILLARD (4,5), Fiona ECARNOT (6), Pascal ANDREU (1), Jean-Baptiste ROUDAUT (1), Marie LABRUYERE (1,4), Jean-Philippe RIGAUD (7,8), Jean-Pierre QUENOT (1,2,4,9)
(1) CHU Dijon - Service de Médecine Intensive & Réanimation, Dijon, FRANCE ; (2) Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (3) Ordre des médecins Rhône-Alpes, Lyon, FRANCE ; (4) INSERM, CIC 1432, Module Épidémiologie Clinique, université de Bourgogne-Franche Comté, Dijon, FRANCE ; (5) DRCI, USMR, CHU Dijon Bourgogne, Dijon, FRANCE ; (6) EA3920, Department of Cardiology, University Hospital Besancon, Besançon, FRANCE ; (7) Centre Hospitalier de Dieppe, Department of Intensive Care, Dieppe, FRANCE ; (8) Espace de Réflexion Éthique de Normandie, University Hospital Caen, Caen, FRANCE ; (9) Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Dijon, FRANCE","contentIntroduction":"The questions raised by Intensive care unit (ICU) physicians with non-ICU physicians and particularly general practitioners (GPs) usually aim to anticipate possible acute decompensation and need for ICU admission in the patient. Intensivists also question their correspondents about the patient’s wishes, with a view to avoiding unreasonable therapeutic obstinacy, or an ICU admission that might later be judged to have been inappropriate. We sought to explore GPs’ perception and experience of ICU, and their manner of anticipating possible future ICU requirements for their patients.","contentPatientsMethods":"We performed a qualitative study using semi-structured interviews with GPs practising in the Burgundy and Pays-de-Loire regions of France. An interview guide was developed in advance, and focused on the following questions: (1) what is your perception of ICU? (2) what is your role in anticipating ICU requirements for your patients? (3) how do you feel about ICU stays that may later be judged to have been unjustified, or inappropriate. Interviews were recorded, transcribed and analysed by thematic analysis. Interviews were performed until theoretical saturation was reached.","contentResultats":"A total of 20 GPs were interviewed between February and August 2021. The main themes to emerge from the analysis were: (1) The GPs perceive ICU care as being that is very far removed from their ordinary daily practice. Their usually rare contacts with ICUs became more common during the COVID pandemic, strengthening relations between GPs and ICUs. (2) Improved knowledge of patients’ wishes by GPs is desirable. This would make it possible, together with specialists during pluridisciplinary meetings, to better guide the patient’s healthcare trajectory. (3) GPs are generally not familiar with the notion of unjustified or inappropriate ICU stays, and do not give it much thought. (4) Advance directives and end-of-life issues should be detailed in the patient’s electronic medical record. However, due to a lack of time and training, GPs do not feel comfortable addressing these questions with their patients.","contentDiscussion":"","contentConclusion":"Anticipating ICU requirements in a patient’s healthcare trajectory is difficult for GPs due to a lack of time, and a lack of training or education about ethical issues, which are not a major preoccupation in their daily practice. There is undoubtedly a compelling need to improve communication between hospital-based specialists, and physicians working in primary care, and to incite the population to think about preparing advance directives.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1219","session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"QUENOT Jean-Pierre"},{"id":99561,"num":"A33913lc","reference":"FC-227","title":"Catastrophic COVID-19 delta variant surge in French West Indies – Report of an ICU triage policy.","formatedAuthors":"Jean-David POMMIER (1), Floran DELAMARE (1), Frederic MARTINO (1), Marc VALETTE (1), Alexandre DEMOULE (2), Laurent CAMOUS (1)
(1) CHU de guadeloupe, Les Abymes, GUADELOUPE ; (2) CHU Pitié-Salpétrière, Paris, FRANCE","contentIntroduction":"Evaluate the results of crisis standards of care based on a multi-approach protocol in ”real life condition”s and the final outcome of all COVID-19 patients that have been proposed for admission to the intensive care unit (ICU) during a catastrophic delta variant SARS COV 2 surge overloading Intensive Care Unit (ICU) initial capacity .","contentPatientsMethods":"All patients hospitalized in the University Hospital of Guadeloupe for Covid-19 pneumonia who were proposed for ICU admission during the surge peak from August 11th to September 10th were included. Retrospective analysis of population characteristics, outcome and death risk factors among patients admitted in ICU was performed.","contentResultats":"For this crisis, an ICU prioritization algorithm based on a multi-approach protocol was employed. According to day by day admission policy, three groups of patients were defined: \"ICU ASAP” , \"ICU maybe” and ” No ICU”. During the one month study period, 328 patients were considered for ICU admission, of whom. 132 (40%) were finally admitted. No “ICU ASAP “patients had to be refused of ICU admission due to Full ICU bed occupancy and 16 of the “ICU maybe” group patients had a secondary withdrawal of care”. In the ICU admitted patients (n =152) ,80 patients were from the “ICU ASAP” group and 52 from the “ICU maybe” group. Hospital mortality was 24% in the “ICU ASAP” patients and 37% in the “ICU maybe” patients. Unsurpringly, the “No ICU” group had a 77% mortality, reflecting severity of the patients. In ICU admitted patients, multivariate analysis found that late admission (>48H after first ICU referral) and Hypertension were independent risk factor of death.","contentDiscussion":"","contentConclusion":"Multi approach protocol overcome a catastrophic COVID 19 Surge in Guadeloupe Island . Late admission (>48H after first referral) was grieved by rised ICU mortality in ICU eligible patients.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1219","session":"FLASH COM - Ethique et réanimation","theme":"Ethique","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"POMMIER Jean-David"},{"id":99562,"num":"A34643sk","reference":"FC-228","title":"Sepsis in the emergency departement: Is procalcitonin predictive of septic shock?","formatedAuthors":"Badra BAHRI (1), Saoussen KHIARI (1), Ines SEDGHIANI (1), Racha GHABARA (1), Hamdi DOGHRI (1), Hajer TOUJ (1), Sonia CHOUAIEB (1), Nebiha BORSALI (1)
(1) hopital habib thameur tunis, tunisie , Tunis, TUNISIE","contentIntroduction":"Sepsis is frequent in the emergency department and a common cause of intensive care unit admission. Early recognition of patients at risk of septic shock is essential. The purpose of our study was to evaluate the prognostic value of procalcitonin (PCT) in patients admitted to the emergency department for sepsis.","contentPatientsMethods":"Prospective monocentric observational study, conducted between July and December 2021. We included patients aged 18 and over, admitted to the emergency department for sepsis with a SOFA score greater than or equal to 2 and a suspected infection. The procalcitonin assay was performed on admission. The primary endpoint was the onset of septic shock. The secondary endpoints were deaths in the emergency department, admission in intensive care and the use of mechanical ventilation.","contentResultats":"We included 137 patients aged on average 63.4 ± 14 years with a sex ratio of 1.49. The sites of infection sepsis were n (%): pulmonary 79 (58) including 60 (43) covid, urinary 38 (27), cutaneous 7 (5), digestive 8 (6), neuromeningeal 2 (1), and infective endocarditis 3 (2). The average PCT value was 9.16 ± 24 ng/ml with extremes of 0.03 to 100 ng/ml. The occurrence rate of a septic shock was 17.6% (n=24) requiring the use of norepinephrine. Overall mortality was 35% (n=48). The use of mechanical ventilation was indicated in 16.8% of cases. The intensive care admission rate was 20% (n=27). The average emergency room stay was 5 ± 0.5 days. The mean PCT in the shock group was 3.1 ng/ml versus 0.64 ng/ml in the non-shock group (p=0.006); the threshold value with the best sensitivities (79%) and specificity (43%) was 0.5 (Odds ratio = 3.6; AUC = 0.67). The mean PCT was 2.38 ng/ml in the deceased versus 0.43 ng/ml in the survivors (p=0.004). The PCT threshold value for predicting mortality with the best sensitivity (68%) and specificity (91%) was 0.7 ng/ml (odds ratio = 2.1; AUC = 0.64). We found no significant difference in the use of mechanical ventilation (p=0.06).","contentDiscussion":"","contentConclusion":"Procalcitonin is a predictive factor for the onset of septic shock and mortality in patients admitted to the emergency department for sepsis.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHABARA Racha"},{"id":99563,"num":"A33940lc","reference":"FC-229","title":"Histoplasmosis in the ICU : Characteristics and Outcome A retrospective study (2014-2021) in the French west indies","formatedAuthors":"Laurent CAMOUS (1), Jean-David POMMIER (1), Arthur SUREL (1), Frederic MARTINO (1), Muriel NICOLAS (1), Michel CARLES (2)
(1) CHU de guadeloupe, Les Abymes, GUADELOUPE ; (2) CHU de Nice, Nice, FRANCE","contentIntroduction":"We aim to retrospectively highlight, in a putative endemic area of histoplasmosis endemic without precise epidemiologic data, the prevalence of severe histoplasmosis requiring ICU.","contentPatientsMethods":"We conducted a retrospective review study of all adult patients (>18 years old ) who developed culture-confirmed histoplasmosis and admitted for a life threatening event in the ICU of Guadeloupe University Hospital (GUH) from January 2014 until June 2021.","contentResultats":"21 patients were included with a median age of 61 (50.0;67.0), mostly men (n=12, 57%). HIV was the most frequent underlying disease (n=8, 38%). All HIV patients, whether treated or not, were severely immunocompromised with a CD4 cell count below 50 per mm3. Other underlying conditions were ongoing immunosuppressive treatments (n=7, 33%), Solid organ transplanted patients (N=3, 14%) and cancer patients (n=2, 10%)) (see Table 1). Three out of the 21 patients had no known immunosuppressive disorders but diabetes.\n The median IGS II at ICU admission was 63 (43.0;81.5). Median of symptoms duration before ICU admission was 23 days . The main clinical conditions requiring ICU admission were acute respiratory failure (n=15, 71%), and/or shock then coma (n=10 50%)","contentDiscussion":"","contentConclusion":"Histoplamosis is a rare but life threatening infection with pleomorphic organ involvement in immunocompromised host.\n Physicians must be aware of diagnosis tools to propose fast antifungal therapy","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"CAMOUS Laurent"},{"id":99564,"num":"A34670CV","reference":"FC-230","title":"Severe community-acquired pneumonia due to Acinetobacter baumannii in Reunion Island : a retrospective observational study","formatedAuthors":"Giacomo ROTINI (1), Axel DEMANGOU (1), Marie BARON (1), Mathilde NATIVEL (1), Bérénice PUECH (1), Julien JABOT (1), Nicolas ALLOU (1), Charles VIDAL (1)
(1) CHU Félix Gyuon , Saint Denis, REUNION","contentIntroduction":"Acinetobacter baumannii (Ab) is usually involved in nosocomial infection especially in intensive care units (ICU). Few studies report series of severe community-acquired pneumonia (CAP) due to this germ, particularly in tropical or sub-tropical regions. The objective of this work is to make an epidemiological analysis of CAP caused by Acinetobacter baumannii (Ab) in Reunion Island.","contentPatientsMethods":"It is a retrospective study including all patients hospitalized for CAP in ICUs at the Reunion University Hospital in the period 2014-2020. CAP to Ab was confirmed by microbiological respiratory samples or blood cultures realized at the admission in ICUs. All patient presented nosocomial infection or pneumonia to Ab were excluded.","contentResultats":"In the inclusion period, 572 patients were hospitalized in the ICUs for severe CAP, 6 of which were attributable to Acinetobacter baumannii (CAP- Ab). Patients with CAP-Ab had more alcohol disorders (67% vs 28%, OR=5, p=0.05) and denutrition state (50% vs 16%, OR= 6.4, p=0.02) than patient with “standard CAP”, 5/6 of patients with CAP-Ab were smokers. There was no statistically significant difference with diabetes, gender, immunosuppression and chronic respiratory diseases. Regarding the clinical presentation, patients with CAP-Ab presented septic shock (100%) and ARDS (67%). SOFA score at admission and mortality were higher (respectively 8 vs 3 and 83% vs 27% OR = 13, p<0.01). All patients of the patients with CAP -Ab had initially received a first inappropriate antibiotic therapy against Ab associating ceftriaxone/cefotaxime and spiramycine.","contentDiscussion":"","contentConclusion":"In Reunion Island, severe CAP due to Acinetobacter baumannii represent 1% of CAP hospitalized in ICU and are associated with high mortality. The severity of the initial clinical presentation as well as the presence of comorbidities such as alcohol disorders and denutrition should suggest this pathogen prompting a larger spectrum antibiotic therapy.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Leung, W.-S. et al. Fulminant Community-Acquired Acinetobacter baumannii Pneumonia as a Distinct Clinical Syndrome. Chest (2006)","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Davis, J. S. et al. A 16-Year Prospective Study of Community-Onset Bacteremic Acinetobacter Pneumonia. Chest (2014)","presentateur":"NATIVEL Mathilde"},{"id":99565,"num":"A34401PG","reference":"FC-231","title":"Safety of early discontinuation of an empiric combination antibiotic regimen in severe community-acquired pneumonia: the STOP study","formatedAuthors":"Pauline GUILLOT (1), Flora DELAMAIRE (1), Benoit PAINVIN (1), Caroline PIAU (1), Florian REIZINE (1), Mathieu LESOUHAITIER (1), Arnaud GACOUIN (1), Jean-Marc TADIE (1), Adel MAAMAR (1)
(1) CHU de Rennes, Rennes, FRANCE","contentIntroduction":"Severe community-acquired pneumonia (SCAP) is a leading cause of infectious mortality and a frequent reason for admission to intensive care unit (ICU). The recommended empirical antibiotic treatment is an association of a β-lactam plus a macrolide or a respiratory fluoroquinolone. Treatment de-escalation strategies are not uniform. Our objective was to assess the safety of discontinuing atypical micro-organism coverage in ICU.","contentPatientsMethods":"We conducted a single-centre observational study over 6 years. Clinical data were collected retrospectively, microbiological data were collected prospectively. All consecutive patients over 18 years admitted to ICU with documented SCAP were included. All patients received an empirical combination therapy with a β-lactam plus a macrolide or quinolone. Legionella urine antigen test (UAT) was performed in all patients at admission. Macrolide or quinolone were discontinued if the UAT was negative. We examined the clinical and epidemiological characteristics of SCAP and analyzed the independent factors associated with ICU mortality.","contentResultats":"On 856 SCAP, 26 patients had atypical pneumonia: 18 Legionella pneumophila (LP) serogroup 1, 3 Mycoplasma pneumoniae (MP), and 5 Chlamydia psittaci (CP). There was no other Legionella serogroup or specie, and no Chlamydophila pneumoniae. UAT diagnosed 16 Legionella pneumonia. Combination therapy was discontinued for 5 patients with an atypical pneumonia: 1 with LP, 1 with MP and 2 with CP. Although the duration of mechanical ventilation was higher in atypical SCAP in univariate analysis, there was no significant difference in length of stay and ICU mortality compared with typical SCAP. The multivariate analysis showed SAPS II score (Odd-Ratio (OR) = 1.04 by 1-point increment; 95% confidence interval (CI) 1.03-1.05, p < 0.001) and the need for mechanical ventilation (OR = 5.4; 95% CI 2.5-13.3, p < 0.001) as independent factors associated with a higher ICU mortality. Type of micro-organism was not associated with a higher ICU mortality.","contentDiscussion":"","contentConclusion":"In the absence of a specific history, it might be safe to discontinue macrolides or quinolones when Legionella UAT is negative. This \"early\" discontinuation strategy reduces antibiotic consumption, which has an economic and ecological impact on the human microbiota and antibiotic resistance. These results need to be confirmed in a multicentre study with a larger cohort.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GUILLOT Pauline"},{"id":99566,"num":"A34602MR","reference":"FC-232","title":"Clinical features and outcome of influenza pneumonia in critically-ill immunocompromised patients","formatedAuthors":"Matthieu RAYMOND (1), Maelle MARTIN (1), Pauline LAMOUCHE-WILQUIN (1), Gauthier BLONZ (1), Paul DESCAMPS (1), Maité AGBAKOU (1), Luc DESMEDT (1), Jean REIGNIER (1), Jean Baptiste LASCARROU (1), Emmanuel CANET (1)
(1) CHU Nantes, Nantes, FRANCE","contentIntroduction":"Immunocompromised patients are at risk of severe viral infections which may require ICU admission. Flu is responsible of yearly epidemic waves and influenza pneumonia may deteriorate into acute respiratory syndrome (ARDS). However, data on the outcome of influenza pneumonia in critically-ill immunocompromised patients are limited.","contentPatientsMethods":"We conducted a single-center observational study. All patients admitted to the ICU of a French university-affiliated hospital for influenza pneumonia between December 1st 2016 and February 28th 2020 were included. The main objective was to compare the clinical features and outcome of critically-ill patients with flu according to their immunocompromised status.","contentResultats":"Overall, 137 patients (age 60 (±2.77) years-old, 58.4% male) were included, of whom 58 (42.34%) were intubated. Forty-three (31.4%) patients were immunocompromised and 94 (68.6%) had no underlying immunosuppression. The main causes of immunosuppression were solid tumor (39.53%), hematological malignancies (37.21%) and solid-organ-transplantation (13.95%). ICU mortality was 13.97%, with mortality of immunocompromised patients being three-times that of patients without immunosuppression (25.58% versus 8.6%, p=0.015).\n Immunocompromised patients were younger (58 vs 64 years-old, p=0.02), had a higher Charlson comorbidity index (5.77 vs 3.12, p<0.0001) and a worse Performance Status (1.72 vs 1.43, p=0.02) compared to non-immunocompromised patients. In contrast, severity scores (SAPS II), hypoxemia (PaO2/FiO2 ratio), and ventilatory support at ICU admission were similar between the 2 groups. During the ICU stay, mechanical ventilation (MV) was implemented in 41.86% of immunocompromised patients and 42.55% of non-immunocompromised patients (p=1). There was no difference in the rate of ventilator-associated pneumonia between the 2 groups (22.2 vs 22.5%, p=1). Among MV patients, 10 (55.5%) immunocompromised patients developed severe ARDS compared to 13 (32.5%) non-immunocompromised patients (p=0.02). \n On univariate analysis, factors associated with ICU mortality were older age, higher Charlson comorbidity index, worse Performance status, higher SAPS II, lower PaO2/FiO2 ratio, immunocompromised status, acute kidney injury, and the use of MV and vasopressors. \n On multivariable analysis, immunocompromised status was the only factor associated with increased ICU mortality (aOR 2.87 (1.07-7.69), p=0.03).","contentDiscussion":"","contentConclusion":"Immunocompromised patients with severe influenza pneumonia were more likely to develop severe ARDS and had a 3-fold increase in ICU mortality compared to non-immunocompromised patients. Such difference was not explained by an increased rate of ICU-acquired infections, suggesting that influenza virus was by itself responsible of a more severe form of pulmonary disease in immunocompromised patients. Further studies are needed to assess whether new antiviral drugs would translate into better patients’ outcome.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"RAYMOND Matthieu"},{"id":99567,"num":"A33926RJ","reference":"FC-233","title":"Relationship between prehospital modified Charlson Comorbidity Index and septic shock 30-day mortality","formatedAuthors":"Pierre-Arnaud PARFAIT (1), Romain JOUFFROY (1,2), Basile GILBERT (3), Jean Pierre TOURTIER (4), Emmanuel BLOCH-LAINE (5), Patrick ECOLLAN (6), Josiane BOULARAN (7), Vincent BOUNES (3), Benoit VIVIEN (2), Papa GUEYE (8)
(1) APHP - CHRU Ambroise Paré, Boulogne-Billancourt, FRANCE ; (2) Intensive Care Unit, Anaesthesiology, SAMU, Necker Enfants Malades Hospital - Assistance Publique - Hôpitaux Paris, Paris, FRANCE ; (3) Department of Emergency Medicine, SAMU 31, University Hospital of Toulouse, Toulouse, FRANCE ; (4) Paris Fire Brigade, Paris, FRANCE ; (5) Emergency Department, Cochin Hospital, Paris, France & Emergency Department, SMUR, Hôtel Dieu Hospital - Assistance Publique - Hôpitaux Paris, Paris, FRANCE ; (6) Intensive Care Unit, SMUR, Pitie Salpêtriere Hospital - Assistance Publique - Hôpitaux Paris, Paris, FRANCE ; (7) SAMU 31, Castres Hospital, Castres, FRANCE ; (8) SAMU 972 University Hospital of Martinique, Fort-De-France Martinique,, FRANCE","contentIntroduction":"In the prehospital setting, early identification of septic shock (SS) at risk of poor outcome is mainly based on clinical vital signs alteration evaluation. The Charlson Comorbidity Index (CCI) is an in-hospital tool used for burden of co-morbidity assessment. \n We report the relationship between the modified prehospital CCI, and 30-day mortality of SS patients initially cared for in the prehospital setting by a mobile ICU (MICU).","contentPatientsMethods":"SS patients defined according to the 2012 sepsis-2 conference cared for by MICU between February 2017 and December 2021 were retrospectively analysed.\n The modified prehospital CCI) calculation was based on the available comorbid conditions collected in the prehospital setting. A threshold of ≥6, was chosen according to previous results.","contentResultats":"Five-hundred and twenty-nine patients with a mean age of 70 ± 15 years old were analysed.\n Presumed origin of septic shock was mainly pulmonary (44%), digestive (25%) or urinary (16%).\n 30 day-mortality reached 31%. Propensity score analysis using a multivariate logistic regression of Inverse Probability Treatment Weighting, found a significant association between the 30-day mortality in the modified prehospital CCI≥6: aOR= 1.11 [1.02 - 1.21], p<10 -3","contentDiscussion":"","contentConclusion":"Among septic shock patients initially cared for by a MICU in the prehospital setting, a significant association between 30-day mortality and the elevation of modified prehospital CCI of at least 6 is useful to early identify a poorer outcome.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PARFAIT Pierre-Arnaud"},{"id":99568,"num":"A33925RJ","reference":"FC-234","title":"Adequacy of probabilistic prehospital antibiotic therapy for septic shock","formatedAuthors":"Anna HASSAN (1), Romain JOUFFROY (1,2), Basile GILBERT (3), Jean Pierre TOURTIER (4), Emmanuel BLOCH-LAINE (5), Patrick ECOLLAN (6), Josiane BOULARAN (7), Vincent BOUNES (3), Benoit VIVIEN (2), Papa GUEYE (8)
(1) APHP - CHRU Ambroise Paré, Boulogne-Billancourt, FRANCE ; (2) Intensive Care Unit, Anaesthesiology, SAMU, Necker Enfants Malades Hospital, Assistance Publique - Hôpitaux de Paris, Université de Paris, Paris, FRANCE ; (3) Department of Emergency Medicine, SAMU 31, University Hospital of Toulouse, Toulouse, FRANCE ; (4) Paris Fire Brigade, Paris, FRANCE ; (5) Emergency Department, Cochin Hospital, Paris, France & Emergency Department, SMUR, Hôtel Dieu Hospital - Assistance Publique - Hôpitaux de Paris, Paris, FRANCE ; (6) Intensive Care Unit, SMUR, Pitie Salpêtriere Hospital - Assistance Publique - Hôpitaux de Paris, Paris, FRANCE ; (7) SAMU 31, Castres Hospital, , Castres, FRANCE ; (8) SAMU 972 University Hospital of Martinique, Fort-De-France Martinique, FRANCE","contentIntroduction":"Guidelines on sepsis management recommend early recognition, diagnosis and treatment, especially early antibiotic therapy (ABT) administration in order to reduce septic shock (SS) mortality. However, the adequacy of probabilistic prehospital ABT remains unknown.","contentPatientsMethods":"From May 2016 to March 2021, all consecutive patients with SS cared for by a prehospital mICU intervention were retrospectively analyzed.","contentResultats":"Among 386 patients retrospectively analyzed, 119 (33%) received probabilistic prehospital ABT, among which 74% received a 3 rd generation cephalosporin: 31% cefotaxime and 42% ceftriaxone. No patient had a serious adverse effect related to ABT administration.\n Overall mortality rate on day-30 was 29%.\n Among the 119 patients with prehospital ABT, bacteriological identification was obtained for 81 (68%) patients with adequate prehospital ABT for 65 patients (80%) of which 10 (15%) deceased on day-30. Conversely, among the 16 (20%) patients with inadequate prehospital ABT, 9 patients (56%) deceased on day-30.\n Prehospital adequate ABT was significantly different between alive and deceased patients on day-30 (p=4.10 -3 ). After propensity score matching, a significant association between adequate prehospital ABT administration and day-30 mortality was observed (aOR = 0.09 [0.01-0.47]).\n Inverse probability treatment weighting with multivariable logistic regression reported a day-30 mortality decrease in the adequate prehospital ABT group: aOR = 0.70 [0.53-0.93].","contentDiscussion":"","contentConclusion":"Among SS cared for by a mICU, probabilistic prehospital ABT is most of the time adequate and associated with a day-30 mortality decrease. Further prospective studies are needed to confirm these results and the weight of prehospital ABT in the prehospital bundle of care for SS.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HASSAN Anna"},{"id":99569,"num":"A34332sb","reference":"FC-235","title":"Usefulness of Procalcitonin for cervicofacial cellulitis prognosis in intensive care.","formatedAuthors":"Sabah BENHAMZA (1,2), Mohamed LAZRAQ (1,2), Youssef MILOUDI (1,2), Abdelhak BENSAID (1,2), Najib EL HARRAR (1,2)
(1) Hôpital 20 Août 1953, CHUIR , Casablanca, MAROC ; (2) Université Hassan II, faculté de médecine et de pharmacie, Casablanca, MAROC","contentIntroduction":"Cervicofacial cellulitis (CFC) is a severe infection of the subcutaneous cellular tissue, and is one of the most serious head and neck infectious emergencies [1]. Procalcitonin (PCT) is a “specific marker of bacterial infection” [2]. Our objective was to evaluate the prognostic value of PCT in CFC in intensive care unit.","contentPatientsMethods":"retrospective cohort over 6 years which covered all patients treated for CFC in intensive care unit at the August 20 hospital in Casablanca. All patients with only one or no PCT assay were excluded.","contentResultats":"47 patients were admitted for CFC during the duration of our study, 30 of whom had at least 2 PCT values. The annual incidence of CFC was 8 cases/year. The average age was 41 years old. The sex ratio was 1. The main medical history of admitted patients was diabetes (33.33%), high blood pressure (22.33%) and poor oral health (22.33%). The front door was dental in 53.33%. The average consultation time was 12 days. The main complications were upper aerodigestive tract obstruction (43.3%), mediastinitis (40%) and meningeal extension (13.3%). Positive PCT was found in 60% of cases. In bivariate analysis, positive PCT at admission was associated with mortality (p=0.04), but not with length of stay (p=0.49) or septic shock (p=0.52) or other clinical or biological parameters. The ascending kinetics of PCT was associated with the duration of hospitalization (0.017) but not with death.","contentDiscussion":"","contentConclusion":"Elevated PCT at admission seems to have prognostic rather than diagnostic value, multicenter studies should confirm this result.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1220","session":"FLASH COM - Infections communautaires","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"1) Bennani-Baïti, A A et al. “Cervicofacial cellulitis: The impact of non-steroidal anti-inflammatory drugs. A study of 70 cases.” European annals of otorhinolaryngology, head and neck diseases vol. 132,4 (2015): 181-4. doi:10.1016/j.anorl.2015.06.004","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"2) Venet, C., et al. “Marqueurs biologiques de l’infection en réanimation chez l’adulte?: place de la procalcitonine Biological markers of infection in critically ill adult patients : role of procalcitonin.” Réanimation, vol. 11, no. 3, May 2002, pp. 156–","presentateur":"BENHAMZA Sabah"},{"id":99570,"num":"A34307TM","reference":"FC-236","title":"Characterization of endotracheal tube biofilm in critically ill patients, lessons from a novel microbiological compartment","formatedAuthors":"Thomas MALDINEY (1), Valentin PINEAU (2), Catherine NEUWIRTH (2), Linda OUZEN (2), Isabelle EBERL (2), Géraldine JEUDY (2), Sophie DALAC (2), Lionel PIROTH (2), Mathieu BLOT (2), Marc SAUTOUR (2), Frédéric DALLE (2), Caroline ABDULMALAK (1), Romain TER SCHIPHORST (1), Paul-Simon PUGLIESI (1), Thomas POUSSANT (1), Agathe OGIER-DESSERREY (1), Isabelle FOURNEL (2), Melchior DE GIRAUD D'AGAY (2), Marine JACQUIER (2), Marie LABRUYÈRE (2), François APTEL (2), Jean-Baptiste ROUDAUT (2), Thibault VIEILLE (2), Pascal ANDREU (2), Sébastien PRIN (2), Pierre-Emmanuel CHARLES (2), Maël HAMET (1), Jean-Pierre QUENOT (2)
(1) William Morey Hospital, Chalon-Sur-Saône, FRANCE ; (2) Dijon University Hospital, Dijon, FRANCE","contentIntroduction":"Biofilm (BF) is considered to have a major impact on the development of ventilator-associated pneumonia (VAP) in intensive care unit (ICU) [Reference 1]. Despite an increasing amount of relevant data regarding the formation of BF [Reference 2], significant results are still lacking to understand the potential implication of endotracheal tube (ETT)-BF dispersal and better characterize the impact of its mesostructure and microbiological singularity on the occurrence of VAP.","contentPatientsMethods":"We conducted a multicenter retrospective observational study in both William Morey general hospital and the University Hospital of Dijon between March and May 2021. Patients admitted in the ICU and in the need for more than 48 hours of invasive mechanical ventilation (MV) were screened for subsequent ETT characterization. Following tracheal extubation, we collected ETT, studied the mesostructural morphology of ETT-deposited BF with confocal microscopy (CM) and compared its microbiological characteristics to other colonization / infection sites.","contentResultats":"A total of 64 ETT were included in the study. Confocal microscopy acquisitions of ETT sections revealed a significant correlation between BF thickness and MV duration as well as two main morphological aspects of ETT-deposited BF (Figure 1A to 1D): a thinner continuous ribbon-shaped (rs) aspect, less likely monobacterial and predominantly associated with Enterobacter spp., Streptococcus pneumoniae or Viridans streptococci, and a thicker discontinuous mushroom-shaped (ms) appearance more likely correlated with the association of bacterial and fungal species in respiratory samples (Figure 1E). The microbiological characterization of ETT-deposited BF and subsequent cartography allowed the identification of additional species only in BF (Figure 1F and 1G) with higher acquired resistance in more than 80 % of analyzed BF phenotypes when compared to other colonization sites from the patient’s environment.","contentDiscussion":"","contentConclusion":"The present study unveils novel morphological and microbiological data regarding ETT-deposited BF characterization and formation in ICU patients. BF sampling as well as microbiological phenotypic cartography returned precious information regarding the acquisition of BF-exclusive species with preeminent antibiotic resistance and would therefore constitute a clinical value added in the perspective of future ETT-deposited BF-based antimicrobial stewardship in critically ill patients at increased risk for VAP.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Fernández-Barat L, Torres A. Biofilms in ventilator-associated pneumonia. Future Microbiology. déc 2016;11(12):1599-610","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Thorarinsdottir HR, Kander T, Holmberg A, Petronis S, Klarin B. Biofilm formation on three different endotracheal tubes: a prospective clinical trial. Crit Care. déc 2020;24(1):382","presentateur":"MALDINEY Thomas"},{"id":99571,"num":"A34321AG","reference":"FC-237","title":"Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation","formatedAuthors":"Antoine GUILLON (1,2), Jeoffrey PARDESSUS (2), Guillaume L’HOSTIS (3), Cindy FEVRE (3), Céline BARC (4), Emilie DALLONEAU (2), Youenn JOUAN (1,2), Elsa BODIER (1,2), Yonatan PEREZ (1,2), Camille THOREY (1,2), Laurent MEREGHETTI (1), Maria CABRERA (2), Mickael RIOU (4), Laurent VECELLIO (2), Sandrine LEGUELLEC (5), Nathalie VOURC'H (2)
(1) CHRU Tours, Tours, FRANCE ; (2) INSERM, Centre d'Etude des Pathologies Respiratoires, U1100, Tours, FRANCE ; (3) Pherecydes Pharma, Research and Development, Romainville, FRANCE ; (4) INRAE, UE-1277 Plateforme d'infectiologie expérimentale (PFIE), Nouzilly, FRANCE ; (5) DTF-Aerodrug, Faculté de Médecine, Tours, FRANCE","contentIntroduction":"Pseudomonas aeruginosa is a main cause of ventilator-associated pneumonia (VAP) with drug-resistant bacteria. Bacteriophage therapy has experienced resurgence to compensate for the limited development of novel antibiotics. However, phage therapy is limited to a compassionate use so far, resulting from lack of adequate studies in relevant pharmacological models. We used a pig model of pneumonia caused by P. aeruginosa that recapitulates essential features of human disease to study the antimicrobial efficacy of nebulized-phage therapy","contentPatientsMethods":"(i) Lysis kinetic assays were performed to evaluate in vitro phage antibacterial efficacy against P. aeruginosa and select relevant combinations of lytic phages. (ii) The efficacy of the phage combinations was investigated in vivo (murine model of P. aeruginosa lung infection). (iii) We determined the optimal conditions to ensure efficient phage delivery by aerosol during mechanical ventilation. (iv) Lung antimicrobial efficacy of inhaled-phage therapy was evaluated in pigs, which were anaesthetized, mechanically ventilated and infected with P. aeruginosa.","contentResultats":"By selecting an active phage cocktail and optimizing aerosol delivery conditions, we were able to deliver high phage concentrations in the lungs, which resulted in a rapid and marked reduction in P. aeruginosa density (1.5-log reduction, p < .001). No infective phage was detected in the sera and urines throughout the experiment.","contentDiscussion":"","contentConclusion":"Our findings demonstrated (i) the feasibility of delivering large amounts of active phages by nebulization during mechanical ventilation and (ii) rapid control of in situ infection by inhaled bacteriophage in an experimental model of P. aeruginosa pneumonia with high translational value.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GUILLON Antoine"},{"id":99572,"num":"A34330BP","reference":"FC-238","title":"Risk factors for a first episode of ventilator-associated pneumonia caused by Stenotrophomonas Maltophilia","formatedAuthors":"Clemence CANIVET (1), Laura TEYSSEYRE (1), Thomas AUJOULAT (1), Margot CARON (1), Mathilde NATIVEL (1), Guillaume MILTGEN (1), Charles VIDAL (1), Nicolas ALLOU (1), Berenice PUECH (1)
(1) CHU Felix Guyon , Saint Denis, REUNION","contentIntroduction":"The incidence of ventilator-associated pneumonia caused by Stenotrophomonas maltophilia (SM-VAP) is on the rise. This pathology is associated with increased morbidity and mortality in intensive care unit (ICU), notably due to intrinsic resistance and ineffective probabilistic antibiotic therapy. Our study aimed to determine the risk factors for a first episode of SM-VAP in ICU.","contentPatientsMethods":"This single center retrospective study was conducted from 2010 to 2018 in the polyvalent ICU of University Hospital. All patients who developed ventilator-associated pneumonia (VAP) during their ICU stay were consecutively evaluated. Patients with a first episode of SM-VAP were compared to those with a first episode of VAP caused by another microorganism.","contentResultats":"A total of 89 patients developed a first episode of SM-VAP over the study period. In the group of patients with SM-VAP, infection was polymicrobial in 43.8% of cases and ICU mortality was 49.4%. After multivariate logistic regression analysis, the risk factors for a first episode of SM-VAP were: chronic respiratory failure (Odds Ratio (OR): 4.212; 95% Confidence Interval (CI): 1.776 – 9.989; p = 0.001), chronic renal failure (OR: 2.693; 95% CI: 1.356 – 5.352; p = 0.05), use of third-generation cephalosporins active against Pseudomonas aeruginosa (OR 2.862; 95% CI: 1.505 – 5.442; p = 0.001), and female sex (OR: 2.646; 95% CI: 1.458 – 4.808; p = 0.001).","contentDiscussion":"","contentConclusion":"In our study, chronic respiratory failure, chronic renal failure, use of third-generation cephalosporins active against P. aeruginosa, and female sex were identified as risk factors for a first episode of SM-VAP.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PUECH Berenice"},{"id":99573,"num":"A34446mz","reference":"FC-239","title":"Ventilator associated pneumonia among severe Covid-19 related ARDS patients","formatedAuthors":"Marwa ZGHIDI (1), Imen BEN SAIDA (1,2), Iyed MAATOUK (1), Dhouha HAMDI (1), Rihab BOUBTANE (1), Mohamed BOUSSARSAR (1)
(1) Farhat Hached University Hospital, Medical Intensive Care Unit, Sousse,TUNISIA, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, Sousse, Tunisia, Sousse, Tunisia, TUNISIE","contentIntroduction":"The pandemic of coronavirus disease 2019 (covid19) has resulted in high rates of hospitalization in intensive care units (ICU) with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia (VAP).\n \n The objectives were:\n to determine the trends in frequencies and to analyze the characteristics, prognosis and risk factors of ventilator-associated pneumonia, in severe Covid-19 related ARDSpatients.","contentPatientsMethods":"This was a retrospective study of patients hospitalized with severe COVID-19 from March 2020 to October 2021, in a medical intensive care unit who required mechanicalventilation for more than 48 h.The study period was divided in three transition stages corresponding to each new adjustment.VAP was identified by using a combination of clinical, imaging and laboratory criteria. Univariate analysis and multivariable logistic regression were used to analyze the associated factors with VAP.","contentResultats":"During the study period, 442 patients with positive RT-PCR COVID-19 were hospitalized in the ICU. Two hundred fifteen (48.6) were mechanically ventilated and met the inclusion criteria. Patients' characteristics were: mean age, 65±12 years; male, 142(66); Median SAPSII on admission, 32[26-38]; Median SOFA on admission, 3[1-4]; Median IMV duration,8[4-12]. The median length-of-stay was at 11[7-17] days. The overall mortality rate was 83%.\n \n Overall, 27(12.5)patients developed VAP with density incidence rate estimated at 10.5 VAP/1000 ventilator days.The three identified periods were respectively,February-October 2020 (9 months)November 2020-April 2021 (6 months);and May-September 2021 (5 months).VAP frequencies were respectively, 6(28.5), 12(11.3) and 9(10.2)at stages 1,2 and 3.\n \n Patients with VAP had significantly longer duration of IMV (9[5-13]vs 7[4-11] days, p=0.007), longer length of ICU stay (12[8-17] vs 10[7-16] days, p=0.007), higher mortality rate (98.5% vs 79.5%, p=0.027) and lower extubation rate (1.5% vs 31%, p=0.001).\n \n The most frequently isolated organism was Acinetobacterbaumannii12(44%). Followed by Pseudomonasa eruginosa, 7(26%); Klebsiella Pneumonia, 4(14.8%) and Candida albicans, 2(7.4%).\n \n The only risk factors independently associated with VAP was duration of IMV (RR, 1.15; 95%CI, [1.04-1.27]; p=0.006).","contentDiscussion":"","contentConclusion":"Mechanically ventilated COVID-19 patients had a high frequency of ventilator-associated pneumonia, varying according to protection measures.IMV duration was identified as independent risk factor for VAP","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ZGHIDI Marwa"},{"id":99574,"num":"A34455AD","reference":"FC-240","title":"Impact of early steroids for COVID-19 related ARDS on ventilator associated pneumonia","formatedAuthors":"Pauline LAMOUCHE-WILQUIN (2), Jérôme SOUCHARD (1), Morgane PERE (2), Matthieu RAYMOND (2), Pierre ASFAR (3), Cédric DARREAU (6), Florian REIZINE (4), Baptiste HOURMANT (7), Gwenhaël COLIN (5), Guillaume RIEUL (1), Pierre KERGOAT (8), Aurélien FRÉROU (9), Julien LORBER (13), Johann AUCHABIE (10), Béatrice LACOMBE (13), Philippe SEGUIN (4), Pierr-Yves EGRETEAU (12), Jean MORIN (2), Yannick FEDUN (1), Emmanuel CANET (2), Jean-Baptiste LASCARROU (2), Agathe DELBOVE (1)
(1) CHBA Vannes, Vannes, FRANCE ; (2) CHU Nantes, Nantes, FRANCE ; (3) CHU Angers, Angers, FRANCE ; (4) CHU Rennes, Rennes, FRANCE ; (5) CHD Vendée, La Roche Sur Yon, FRANCE ; (6) Centre hospitalier du Mans, Le Mans, FRANCE ; (7) CHU Brest, Brest, FRANCE ; (8) Centre hospitalier de Cornouaille, Quimper, FRANCE ; (9) Centre hospitalier de St Malo, St Malo, FRANCE ; (10) Centre hospitalier de Cholet, Cholet, FRANCE ; (11) CH Morlaix, Morlaix, FRANCE ; (12) CH Saint Nazaire, St Nazaire, FRANCE ; (13) Centre hospitalier Bretagne Sud, Lorient, FRANCE","contentIntroduction":"Few data about long-term outcome (including infectious complications) of early steroids course for COVID-19 related acute respiratory distress syndrome (ARDS) are available. This multicentric retrospective cohort study aims to determine the influence of an early course of steroids on ventilator associated pneumonia (VAP) incidence in COVID-19 patients under mechanical ventilation (MV).","contentPatientsMethods":"We included patients over 18 years old admitted in ICU for SARS-CoV2 related ARDS under MV for at least 48 hours in 15 ICUs. Inclusion period was from 1st January to 31st December of 2020. Early steroid group (ESG) was defined by administration of corticosteroids within 24h of admission whereas control group (CG) did not. The main study outcome was VAP incidence. Secondary outcomes included day 90 mortality, MV duration, other organ dysfunctions and VAP characteristics.","contentResultats":"We included 670 patients of mean age 67 years-old, of whom 369 in ESG and 301 in CG. Sex ratio (73.9% male), rate of hypertension (55.2%) and diabetes (31.2%) was similar between groups. ESG was slightly older (mean age 66.7±10.2 vs 63.5±11.3 years-old, p=0.0001), had greater BMI (30.4±6.0 vs 28.9±5.4 k/m², p=0.0007), more immunosuppression (20.3% vs 10.6%, p=0.0007) and a greater Charlson score (4.3±2.5 vs 3.1±2.2, p<0.0001). Mean PaO2/FiO2 ratio upon admission was 143±67. The cumulative incidence of VAP with death and extubation as competing events was higher in ESG, with a Hazard Ratio (HR) of 1.29 (CI95%[1.05; 1.58], p=0.016). Antibiotic therapy was active on future identified bacteria on 80.8% vs 74.6% patients in ESG vs CG (p=0.18). Bacterial antibiotic resistance of VAP was not different (OR 0.94, CI95%[0.58; 1.53], p=0.81). In univariate analysis, there was no difference in day-90 mortality between groups with 30.9% in ESG vs 24.3% in CG (p=0.111). In a multivariate analysis, there was no difference in day-90 mortality in both group (HR 1.15, CI95%[0.83; 1.60], p=0.411). VAP was associated with a higher day-90 mortality (HR 1.63; CI95%[1.17; 2.28], p=0.0003). Each increase of 1 years-old (HR 1.05, CI95%[1.03; 1.07], p<0.001) and increase of 1 point of SOFA score (HR 1.15, [1.09;1.22], p<0.0001) were also associated with an increase of mortality.","contentDiscussion":"","contentConclusion":"In this retrospective study, early use of steroids was associated with an increased risk of developing VAP in mechanically ventilated COVID-19 patients. Risk of death was higher in presence of VAP, but day-90 mortality did not reach statistical difference between groups. This results suggests VAP associated mortality could counterbalance steroids benefits in this population.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAMOUCHE-WILQUIN Pauline"},{"id":99575,"num":"A34488AG","reference":"FC-241","title":"Prolonged antimicrobial treatment over than 7 days is associated with lower recurrence of VAP in patients with COVID-19 related ARDS","formatedAuthors":"Ariane GAVAUD (1), Laura TERRACOL (1), Ahmed BOUGHDIRI (2), Etienne CANOUI (1), Julien CHARPENTIER (1), Hélène POUPET (1), Claire POYART (1), Jean-Paul MIRA (1), Nabil GASTLI (1)
(1) Hôpital Cochin, Paris, FRANCE ; (2) Ecole des Ponts, Champs-Sur-Marne, FRANCE","contentIntroduction":"Patients hospitalized in the intensive care unit (ICU) for COVID-19 related acute respiratory distress syndrome (ARDS) are at high risk for recurring ventilator-acquired pneumonia (VAP), that are associated with poor outcome. The aim of this study was to describe characteristics of first episode and recurrences of VAP along the 3 first epidemic waves, and to identify determinants involved in the recurrence, including host, microbiological and treatment factors.","contentPatientsMethods":"We conducted a retrospective observational study in a 24-bed ICU between March 2020 and May 2021. All adult patients admitted for severe COVID-19 pneumonia requiring >48 hours of mechanical ventilation were consecutively included. VAP episodes were diagnosed using clinical, radiological and quantitative microbiological criteria. VAP recurrence was defined as reappearance of VAP criteria after antibiotic discontinuation, with at least one bacterial species growing at a significant concentration from a new respiratory sample. Recurrence was considered a “relapse” if at least one of the initial causative bacterial strains grew at a significant concentration from a second distal sample; otherwise, it was considered a “superinfection”. Among patients with first episode of VAP, we investigated determinants associated with recurrence using logistic regression analysis with Cox-model. Primary outcome measurement was ICU discharge without VAP recurrence.","contentResultats":"Of 154 included patients, 115 (75%) presented a first episode of VAP. At least one recurrence occurred in 64/97 (66%) patients who survived from the first episode, with same pathogen in 49/64 (76%) patients (relapse). Enterobacteriaceae (56%) and Staphylococcus aureus (37%) were the most frequently isolated in the first episode, while recurrences recovered mainly Enterobacteriaceae (67%) and non-fermenting Gram-negative bacteria (53%).\n Infection with Methicillin-susceptible S.aureus was associated with an increased risk of recurrence within 7 days after antimicrobial treatment interruption (HR for absence of recurrence: 0.3[0.1-0.9]) compared with other pathogens.\n The ICU mortality was 32% in our study population. Among patients who survived the first episode of VAP, recurrence was correlated with poorer outcome (mortality of 34% vs 9% if no recurrence; P = 0.006)\n Prolonged duration of antimicrobial treatment (>7 days), as well as appropriate empiric antimicrobial treatment were associated with an increased probability of ICU discharge without VAP recurrence: HR 7.3 [2.2-24.1] and HR 2.7 [1.0-7.0].","contentDiscussion":"","contentConclusion":"In COVID-19 related ARDS patients treated for first VAP episode, prolonged duration of antimicrobial treatment may be a possible key to reduce VAP recurrences and have a beneficial impact on prognosis in ICU.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GAVAUD Ariane"},{"id":99576,"num":"A34648CA","reference":"FC-242","title":"Procalcitonin kinetics as a prognostic marker of ventilator associated pneumonia","formatedAuthors":"Camille AQUIN (1), Clara VIGNERON (2), Philippe CHARBONNEAU (3), Vincent Quoc Huy TRINH (4), Jean-Pierre QUENOT (1), Pierre-Emmanuel CHARLES (1)
(1) Centre Hospitalier Universitaire, Dijon, FRANCE ; (2) Hôpital Cochin, Paris, FRANCE ; (3) Centre Hospitalier de l'Université de Montréal, Montréal, CANADA ; (4) Vanderbilt University Medical Center, Nashville, ETATS-UNIS","contentIntroduction":"Ventilator associated pneumonia (VAP) is a common and serious infection that is often difficult to diagnose. Biomarkers have been proposed as a diagnostic tool. The assay of procalcitonin (PCT) is not recommended for diagnostic purposes, but numerous studies have shown its prognostic value. The use of the kinetics, rather than an absolute value, seems more relevant.","contentPatientsMethods":"Patients with an episode of VAP between December 2005 and October 2017 were identified. After excluding the missing data, 518 patients were included and divided into three groups according to their procalcitonin kinetics between D2 and D3 (Group 1: ΔPCTD2-D3 ≥ 30% ; group 2: ΔPCTD2-D3 = [1-29%]; group 3: ΔPCTD2-D3 ≤ 0%).","contentResultats":"The 1st group (148 patients) had a 28-day mortality of 29,7%, the 2nd group (212 patients) of 42,9%, and the 3rd group (158 patients) of 50,6%. Mortality was greater in group 3, after univariate (p = 0.001) and multivariate (p = 0.014) analysis. Multivariate analysis identified age, cirrhosis, chronic renal failure, and belonging to group 3, as independant factors associated with mortality.","contentDiscussion":"","contentConclusion":"Our study suggests that the kinetics of procalcitonin between the following day and two days after the diagnosis of VAP (D2-D3) may be a prognostic marker of mortality. The identification of factors associated with mortality could allow the early identification of patients at risk in order to optimize their management.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"CHARLES Pierre-Emmanuel"},{"id":99577,"num":"A34435ED","reference":"FC-243","title":"Volume variation of endotracheal aspirates to predict onset of ventilator-associated pneumonia","formatedAuthors":"Estelle DANCHE (1), Sylvain MEYER (1), Elie GUICHARD (2), Ana Catalina HERNANDEZ PADILLA (1), Anne-Laure FEDOU (1), Philippe VIGNON (1), Olivier BARRAUD (1), Bruno FRANÇOIS (1)
(1) CHU Dupuytren, Limoges, FRANCE ; (2) CHRU de Tours, Tours, FRANCE","contentIntroduction":"Ventilator-associated pneumonia (VAP) is the most common cause of infection in the ICU but its diagnosis remains challenging. In this context, the CPIS, one of the most universal VAP score may help. Most of its component may be modified by “external factors” and therefore CPIS is in fact neither very specific neither very sensitive. Endotracheal secretions are one of the clinical criteria used for the diagnosis of VAP in CPIS and European and American guidelines. However, few studies analysed the properties of those secretions, and their dynamics during mechanical ventilation. We hypothesized that endotracheal secretions volume modifications could help to early identify patients developing VAP.","contentPatientsMethods":"We conducted a prospective study in adult patients requiring mechanical ventilation (MV) for at least 7 days. Included patients had to be free from acute or chronic pulmonary disease and from any acute infectious disease or antibiotic treatment before inclusion. Mostly neurological patients, including trauma were targeted to have a “very clean” population. Patients were included from intubation and all endotracheal secretions collected as part of routine care by bedside nurses were collected until D7. Daily secretions volume and appearance were measured as well as all CPIS components. All VAP events were retrospectively validated by a blinded adjudication committee. We analysed the progression of CPIS during the first week of ventilation, and the variations in volume aspirates to identify different group pattern. Descriptive statistics were used to describe the study cohort. Spaghetti plot was used to visualize individual trajectories according to the VAP events.","contentResultats":"Forty-eight patients were analysed [28 men; 58 (±15) years old, BMI 26.4 (±6.6), Apache II score 14.3 (±5.3), Charlson Comorbidity Index of 2.8 (±1.9)]. Ten (21%) patients developed VAP and 1556 ETA samples were analysed. Although the volume aspirate tends to increase during mechanical ventilation in all patients (figure), we did not find differences between patients with or without VAP, and no pattern could be identified. The mean and standard deviation of volume aspirate for patients without VAP being high, it covered the value of patient with VAP. Concerning the CPIS, our study shows the absence of relevance of the CPIS, independently from the infectious status.","contentDiscussion":"","contentConclusion":"Our study did not permit to identify pattern for patients at risk of VAP, using the daily volume aspirate or the CPIS.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1221","session":"FLASH COM - PAVM","theme":"Infectiologie","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DANCHE Estelle"},{"id":99578,"num":"A34722JA","reference":"FC-244","title":"Serial measurements of serum procollagen III and hyaluronic acid correlate with lung fibroproliferation during COVID-19 associated acute respiratory distress syndrome.","formatedAuthors":"Jerome ALLARDET-SERVENT (1), Aurelie DEHAENE (1), Anne PLAUZOLLES (4), Claude SOMMA (2), Donatienne BOURLARD (6), Veronique SECQ (3), Yannis BOUAMRA (5), Hacene KHIRI (4), Jean-Marie FOREL (3), Xavier Benoit D'JOURNO (3)
(1) HOPITAL EUROPEEN MARSEILLE, Marseille, FRANCE ; (2) HOPITAL DE LA TIMONE, Marseille, FRANCE ; (3) HOPITAL NORD, Marseille, FRANCE ; (4) LABORATOIRE ALPHABIO, Marseille, FRANCE ; (5) LABORATOIRE EUROFINS BIOMNIS, Ivry Sur Seine, FRANCE ; (6) LABORATOIRE EUROFINS PATHOLOGIE, Marseille, FRANCE","contentIntroduction":"Fibroblastic proliferation with organizing fibrosis occurred in the late stage of COVID-19 related acute respiratory distress syndrome (CARDS)1. Monitoring lung fibroproliferation would help to timely introduce rescue corticosteroids therapy (CST). This study investigates the value of serial measurements in serum of three extracellular matrix (ECM) biomarkers to detect lung fibroproliferation during CARDS2.","contentPatientsMethods":"Five patients with lung fibrosis following CARDS were studied. All patients had reticulations and bronchiectasis on CT scans and three had lung biopsy with confirmed histologic fibrosis. Three patients who underwent elective thoracic surgery and had normal preoperative lung function served as controls. The concentrations of amino-terminal propeptide of type I and type III procollagens (PINP, PIIINP) and hyaluronic acid (HA) were measured weekly using radioimmunoassay (UniQ® RIA, Aidian Oy, Espoo, Finland ) and immunoturbidimetric method (HA LT, FUJIFILM Wako Chemicals, Neuss, Germany). A PIIINP level above 16 µg/L indicated high probability of lung fibrosis2. Cut-offs for PINP and HA have not yet been established. Comparisons were performed using Mann-Whitney U test and correlation with the Rho Spearman’s test. Data are presented as median and interquartile.","contentResultats":"The five fibrotic patients were mostly male (80%), aged 58 [52,70] years, and had normal respiratory function prior admission. All received mechanical ventilation with a median duration of 37 [32,71] days and three required veno-venous extracorporeal membrane oxygenation during 20 [13,21] days. Only one patient survived (Case F-5).\n The average concentrations of PIIINP and HA over the stay were higher in fibrotic patients compared to controls, respectively 14 [9.2,22] vs. 2.5 [2.2,4] µg/L (p=0.005) and 311 [143,699] vs. 37 [22,80] µg/L (p=0.007). In contrast, PINP did not differ between cases (37.5 [21,53] µg/L) and controls (40 [19.8,44.5] µg/L; p=0.64). Figure 1 displayed the time course of biomarkers in fibrotic individuals. The time-weighted average concentrations of PIIINP and HA correlated with the amount of histologic lung fibrosis (respectively ρ=0.749, p=0.032 and ρ=0.687, p=0.059). Serum PIIINP levels overcrossed the predefined fibrosis threshold in all cases within a median delay of 16 (14,25) days.","contentDiscussion":"This proof-of-concept study is the first to describe the course of three ECM biomarkers in the serum of patients with CARDS related lung fibrosis. Only PIIINP and HA exhibited dynamic variations, increased average concentrations and correlated with histologic fibrosis. PIIINP levels exceeded the predefined fibrosis threshold in all fibrotic patients.","contentConclusion":"The non-invasive monitoring of lung fibroproliferation using serial measurement of PIIINP in serum represents a promising strategy and warrants larger investigations.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Carsana, L et al. Pulmonary Post-Mortem Findings in a Series of COVID-19 Cases from Northern Italy: A Two-Centre Descriptive Study. The Lancet Infectious Diseases 2020, 20 (10), 1135–1140.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Forel, J.-M et al. Type III Procollagen Is a Reliable Marker of ARDS-Associated Lung Fibroproliferation. Intensive Care Med 2015, 41 (1), 1–11.","presentateur":"ALLARDET-SERVENT Jerome"},{"id":99579,"num":"A34694IA","reference":"FC-245","title":"Impact of extent parenchymal lesions on critically ill COVID-19 patient outcomes","formatedAuthors":"Ilef ALILA (1), Sana KHARRAT (1), Rihab BOUBTANE (1), Olfa TURKI (1), Malek HAFDHI (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) hopital Habib Bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"During the COVID-19 pandemic, thoracic computed tomography (CT) has proven to be a useful tool not only for diagnosis but also for assessing the extent of SARS-COV2 lesions and detecting possible thoracic complications. The aim of our study was To assess the risk of death or use of invasive mechanical ventilation (IMV) in patients hospitalized with SARS-COV2 pneumonia according to the percentage of lung parenchymal injury.","contentPatientsMethods":"This was a retrospective study conducted in a medical intensive care unit for 16-month period from September 2020 to December 2021. Patients hospitalized with SARS-COV2 pneumonia who received a chest CT scan within the first 48 hours of their stay in the ICU were collected.","contentResultats":"This study included 440 COVID-19 patients, with a mean age of 59.7 ± 14.3 years and a male predominance (sex ratio= 1.75). On admission, 328 patients had severe acute respiratory distress syndrom (ARDS) (74.5%). Invasive mechanical ventilation was required in 196 (44.5%) patients and overall mortality was of 48 % (210patients). Severe lung damage ranging among 75% of the lung parenchyma was estimated in 117 patients (26.6%), of which 99 patients had severe ARDS on admission (85%), 62 patients had required mechanical ventilation (53%; p=0.036), and 64 had developed infections during hospitalization (55%, p=0.036). Comparison between patient outcomes according to the extent of parenchymal lesions on CT is shown in table I.","contentDiscussion":"","contentConclusion":"Initial quantitative assessment of COVID-19 lesions may predict severity and outcomes in patients admitted with SARS-COV2 pneumonia.","published_at":"2022-06-16T16:01:26.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:26.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALILA Ilef"},{"id":99580,"num":"A34489SM","reference":"FC-246","title":"Are CT-scan severity scores accurate in predicting outcome in ICU COVID-19 patients: A cohort validation","formatedAuthors":"Syrine MAATOUK (1), Manel LAHMAR (1), Zeineb HAMMOUDA (1), Jamel SAAD (1), M BETBOUT (1), Ahmed ZRIG (1), Fekri ABROUG (1), Lamia BESBES (1)
(1) CHU Fattouma Bourguiba Monastir, Monastir, TUNISIE","contentIntroduction":"Several chest CT severity scores have been developed during the covid-19 pandemic. These scores were usually higher in patients with critical disease compared to those with less severe disease.\n The aim of this study is to compare the performance of two CT scoring methods in predicting the risk of intubation in patients initially managed with non-invasive ventilation (usually HFNO).","contentPatientsMethods":"A single-center prospective analysis conducted during a 5-months period (from September 2020 to January 2021).\n All patients admitted to ICU with RT-PCR confirmed covid-19 infection and requiring HFNO as a respiratory support were included.\n All CT-scan images were analysed according to two scores. The first one was widely used during the pandemic, gives precedence to the extension of the lesions, an extension expressed in a semi-quantitative way (<25%, 25-50%, 50-75%, >75%) and gives less importance to the nature of the lesions or their distribution, in particular in the antero-posterior dimension. The second score is an older one, first proposed during the H1N1 epidemic, and later on applied in several studies on ARDS. It divides each of the two lungs into 6 quadrants with 3 anteroposterior and longitudinal divisions. Weighing is assigned according to location and type of lung injury. This score ranges from zero to 72.\n We compared the performance of these two scores in predicting HFNO failure by calculating the area under the receiver operating characteristic (ROC) curves (AUC).","contentResultats":"During the study-period, a total of 137 patients were admitted for covid-19 ARDS. From this cohort, we included 106 patients with a positive RT-PCR test and available chest CT scan. This population included 76 (71.7%) male and 30(28.3%) female with a median age of 62.5 years (IQR 53.75-69).\n All patients were put under HFNO at admission of whom 29 (27.4%) patients required invasive mechanical ventilation.\n The most common lesions of the disease included ground glass opacities (GGO) present in 103 (97.2%) patients, followed by consolidations (n=83, 78.3%) and crazy paving pattern (n=62, 58.5%).\n Both scores were well correlated (Pearson correlation coefficient of 0.75). The AUC for Score 1 was 0.73 (95% CI 0.623-0.843) with a p value and the CT score 2 had an AUC of 0.81 (95% CI 0.719-0.911) with a p value of 0.000 (fig 1).","contentDiscussion":"","contentConclusion":"These data suggest the potential role of CT scores for predicting the ventilatory outcome of SARS-CoV-2 patients . Both scores had a good discrimination for patients with higher risk of intubation.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAHMAR Manel"},{"id":99581,"num":"A34496ZG","reference":"FC-247","title":"Is Chest Computed Tomography in COVID-19 inpatients at the ICU predective of severity ?","formatedAuthors":"Zoé GHIGO (1), Didier SORIAL (1), Malo EMERY (1), Matthias BABIN (1), Serge CARREIRA (1)
(1) Hopital Saint Camille, Bry-Sur-Marne , FRANCE","contentIntroduction":"In December 2019, a new coronavirus, named SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), was discovered in the Hubei province of China, causing numerous cases of pneumonia in the World, to the point of getting the status of pandemic in March of 2020. Worldwide, the use of chest computed tomography (CT) to facilitate the management of the COVID-19 crisis has been uneven. Despite many scientific publications on COVID-19, very few of them have evaluated the prognostic use of CT at admission in the emergency room. Our study was conducted in order to determine a potential correlation between the percentage of lung damage on CT scans at admission in patients with positive COVID-19 RT-PCR and their prognosis.","contentPatientsMethods":"This monocenter, observational, retrospective study aims to establish the prognostic value of the CT scan at admission in the emergency room based on the percentage of lung damage on CT scans at admission. Our secondary goals were to determine the clinical characteristics of patients admitted in the emergency room with a COVID-19 infection, and to report the non-clinical characteristics associated with a poor prognosis.","contentResultats":"From March 3rd to May 9th 2020, 293 patients admitted at the emergency room or the ICU for a COVID-19 infection and who underwent through a CT scan at admission were included in our study. After splitting our population between 3 groups, based on the percentage of lung damage on the CT scans (<50%, >50%, atypical), we found that 42% of patients presenting more than 50% of lung damage on the CT scan at admission were deceased or admitted at the ICU 7 days after admission (versus 20% and 12% in the 2 other groups, p < 0,01). In multivariable analysis, the sole percentage of lung damage on CT scans was associated with a poor prognosis (RR 3.37 [1.6-7.12], p = 0.02). The interpretation of the CT scan is bound to an inter-individual variation (Kappa-Cohen coefficient going from 0.19 to 0.53). The severity score of the CT scan was better associated with prognostic 7 days post admission when the CT was read by an expert radiologist (AUC = 0.714), versus automated severity score (AUC = 0.675) or by the on-call radiologist (AUC = 0.657).","contentDiscussion":"","contentConclusion":"CT scans at admission for patients with a COVID-19 infection are useful to predict admission in the ICU or mortality 7 days post admission.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHIGO Zoé"},{"id":99582,"num":"A34731IM","reference":"FC-248","title":"Role of echocardiography in the management and prognosis of patients admitted for acute respiratory failure in a tunisian intensive care unit","formatedAuthors":"Iyed MATOUK (1), Zeineb HAMMOUDA (1), Emir BEDHIAFI (1), Hedia BEN AHMED (1), Fadwa HOURI (1), Nabil BOUGUEZZI (1), Manel LAHMAR (1), Fahmi DACHRAOUI (1), Fekri ABROUG (1), Lamia OUANES-BESBES (1)
(1) University Hospital Fattouma Bourguiba of Monastir (Tunisia), Monastir, TUNISIE","contentIntroduction":"Echocardiography is a crucial tool for the management of patients admitted in intensive care units (ICUs). Indeed, it is widely available and non-invasive. It offers vital data for diagnosis and treatment of the most common pathological conditions encountered in critically ill patients such as acute respiratory failure (ARF). We aimed to determine the role of echocardiography in the diagnosis, therapeutic changes and prognosis among patients admitted for ARF.","contentPatientsMethods":"We conducted a retroprospective study in the ICU of ta Tunisian University Hospital from January 2017 to June 2020. All patients aged over 18 years admitted for ARF and receiving at least one echocardiography in our department were included.","contentResultats":"A total of 346 patients received an ultrasound examination (476 echocardiographies). Almost two thirds were male (72.5%). Median age was 65 [55,72] years. The main medical history was respiratory diseases (61%). Fifty percent were under non-invasive ventilation and 48.3% under mechanical ventilation. Median duration of ventilation was 10 [5, 17]. Among the TTEs, 87.1% were performed within 48 hours of admission. Main indication of echocardiogarphy was suspicion of an increase in left ventricular filling pressures (38.7%) (mean E/E′ ratio was 10.4 ± 3.6, and mean E/A ratio was 1.4 ± 0.8). The main abnormalities of echocardiographic examinations were right heart dysfunction and left ventricular diastolic dysfunction (47.7% and 46% respectively). Echocardiography allowed an hemodynamic monitoring in 25.7%. Echocardiography changed or clarified the initial diagnosis in 67.9%. In total, 67.9% of patients received a therapeutic change after an echocardiographic examination mainly Lasilix (42.3%) and limitation of vascular filling (36%). Mortality rate was 30.9%. Almost 10% of the patients had RV/LV ratio > 1. The majority of patients who survived (90.9%) had RV/LV ratio < 1 (p=0.6). Mean LVFE was 52.3 ± 13.1 in patient who died and 56.7 ± 9.2 in survivors (p=0.002). Mean PAPS was 55.2 ± 16.5 in patient who died and 48.4 ± 13.2 in survivors (p=0.05). The majority of patients who survived received a therapeutic change (64.4%) (p=0.03).","contentDiscussion":"","contentConclusion":"Our study confirms the importance of echocardiographic examination in the diagnosis, hemodynamic monitoring, therapeutic changes, and prognosis in ICU, particularly in patients admitted for ARF. Thus, intensivists should have the necessary training for better patient management.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MATOUK Iyed"},{"id":99583,"num":"A34657MC","reference":"FC-249","title":"Radiographic Assessment of Lung Edema (RALE) score, oxygenation and compliances to predict End-Expiratory Lung Volume and Outcomes in mechanically ventilated patients","formatedAuthors":"Maëva CAMPFORT (1), Pierre-Yves OLIVIER (1), Antoine STUDER (2), Bertrand PAVLOSKY (1), Pierre LEPROVOST (1), Christophe DESPREZ (1), Elise YVIN (1), Mathilde TAILLANTOU-CANDAU (1), Dara CHEAN (1), Antonin COURTAIS (1), Hamid MERDJI (2), Jean-Christophe RICHARD (1), Ferhat MEZIANI (2), Alain MERCAT (1), François BELONCLE (1)
(1) CHU Angers, Angers, FRANCE ; (2) CHRU Strasbourg, Strasbourg, FRANCE","contentIntroduction":"Beside oxygenation and respiratory mechanics, chest radiograph has been proposed to estimate the extent of lung injury and to predict the outcomes of mechanically ventilated patients at the bedside. The Radiographic Assessment of Lung Edema (RALE) score has thus been shown to correlate with edema in lung explants and with hypoxemia and survival in patients with acute respiratory distress syndrome (ARDS) (1). Its clinical value has however not yet been assessed in a general ICU population of mechanically ventilated patients with or without ARDS criteria. This study aimed to assess whether the RALE score can allow to predict the end-expiratory lung volume (EELV) and the outcomes in mechanically ventilated patients, differently from oxygenation or lung and respiratory system compliances.","contentPatientsMethods":"All patients admitted to two ICUs and mechanically ventilated for any cause were prospectively enrolled. Gas exchange, respiratory mechanics (including esophageal pressure measurements), end-expiratory lung volume (EELV, using the nitrogen wash-out wash-in technique) and chest radiograph were assessed within 36 hours after intubation when the patients were ventilated in volume-controlled ventilation (tidal volume = 6 mL/kg predicted body weight (PBW)) with a positive end-expiratory pressure of 5 cmH2O. The RALE score, in which the four quadrants of the chest are scored on a numerical scale for extent of consolidation and density of opacification, was independently assessed by two investigators.","contentResultats":"217 patients were enrolled (124 men (83%), age 65 [56-77]). 104 patients (48%) had ARDS criteria according to the Berlin definition. The RALE score was 19.9 [8.5-31.0]. The RALE score, respiratory system compliance, lung compliance and PaO2/FiO2 ratio were well correlated to EELV/PBW (r=-0.39, p<0.001; r=0.51, p<0.001; r= 0.60, p<0.001 and r=0.41, p<0.001, respectively). The RALE score was lower in patients who survived at day 60 than in those who did not survive (16.5 [6.1-27.3] vs 22 [12.0-32.0], p<0.05). The respiratory system compliance was not different between the survivors and the non-survivors at day 60 (48 [39-58] vs 46 [36-57] mL/cmH2O, p=0.32), neither was the lung compliance (83 [60-101] vs 73 [49-94] mL/cmH2O respectively, p=0.06). The PaO2/FiO2 ratio was lower in the survivors than in the non-survivors at day 60 (201 [147-263] vs 155, [103-257]), p<0.05).","contentDiscussion":"","contentConclusion":"The RALE score measurement may allow to estimate the end-expiratory lung volume, similarly to the assessment of oxygenation or compliances and to predict mortality at day 60 in mechanically ventilated patients.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, et al. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. Thorax. 2018 Sep;73(9):840–6.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"CAMPFORT Maëva"},{"id":99584,"num":"A34745JA","reference":"FC-250","title":"Early measurement of alveolar epithelial and endothelial biomarkers in serum predicts the need for mechanical ventilation in patients with COVID-19 pneumonia.","formatedAuthors":"Jerome ALLARDET-SERVENT (1), Nathalie HEZARD (2), Christel PISSIER (3), Lucas BENAROUS (1), Philippe HALFON (1), Jean-Louis MEGE (4), Marie-Christine ALESSI (2), Pierre MORANGE (2)
(1) HOPITAL EUROPEEN MARSEILLE, Marseille, FRANCE ; (2) HOPITAL DE LA TIMONE, Marseille, FRANCE ; (3) HOPITAL NORD , Marseille, FRANCE ; (4) INSTITUT HOSPITALO-UNIVERSITAIRE DE MALADIES INFECTIEUSES, Marseille, FRANCE","contentIntroduction":"Predicting early the need for mechanical ventilation (MV) during COVID-19 is highly relevant for triage. Biomarkers of alveolar epithelial and endothelial injuries might be helpful in this context. This study investigates the value of four biomarkers in patients hospitalized for moderate to severe COVID-19 pneumonia.","contentPatientsMethods":"Fifty four patients with laboratory confirmed COVID-19 pneumonia were prospectively included and compared to 20 healthy controls. The primary end-point was the need for MV during the stay. The concentrations of four biomarkers were measured in the serum within the first 48 hours following hospital admission: Krebs von den Lungen 6 (KL-6), soluble receptor for advanced glycation end-products (sRAGE), angiopoietin-2 (ANG-2), and club cell protein 16 (CC-16). KL-6 was quantified by chemiluminescent enzyme immunoassay using the Lumipulse® analyzer (Fujirebio, Tokyo, Japan) and the three other biomarkers using enzyme linked immunosorbent assays (Quantikine® ELISA, R&D, Minneapolis, USA). All measurements by ELISA were duplicated and averaged. Biomarkers concentrations were compared between three groups (controls, COVID-No MV and COVID-MV) using the Kruskal-Wallis test with Conover post-hoc comparisons. Receiver operating characteristic (ROC) analysis was used to determine the area under the curve (AUC) of biomarkers to predict MV requirement and the best cut-off was determined using the Youden index method. Continuous data are presented as median and interquartile.","contentResultats":"COVID-19 patients were mostly male (76%), aged 63 [53,71] years, and 21 (39 %) were obese. Eighteen COVID-19 patients (33%) received standard oxygen therapy in the ward while 36 (67 %) required ICU admission. Among ICU patients, 13 (24 %) received high flow oxygen therapy and 23 (43%) required MV. Four patients received extracorporeal membrane oxygenation. Seven patients (13%) deceased.\n Compared to healthy controls, the concentrations of KL-6 and sRAGE were higher in both group of COVID-19 patients (Figure 1). ANG-2 was higher in COVID-MV than controls. CC-16 did not increased in COVID-19 patients. Among COVID-19 patients, those requiring MV had higher levels of KL-6, sRAGE and CC-16 compared to the others. Three biomarkers (sRAGE, CC-16 and KL-6) were predicting the need for MV but the sRAGE performed better with an AUC of 0.786 for a cut-off above 5449 pg/mL.","contentDiscussion":"This study is the first to compare the performance of four biomarkers. We observed similar range of KL-6 than others1 but higher sRAGE levels in MV patients2.","contentConclusion":"sRAGE, KL-6 and ANG-2 concentrations are increased in the serum of patients with COVID-19 pneumonia but sRAGE best predict the need for MV.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1222","session":"FLASH COM - Biomarqueurs dans le SDRA","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"d’Alessandro, M et al. Serum KL-6 Concentrations as a Novel Biomarker of Severe COVID-19. J Med Virol 2020, 92 (10), 2216–2220.","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Kapandji, N et al. Importance of Lung Epithelial Injury in COVID-19-Associated Acute Respiratory Distress Syndrome: Value of Plasma Soluble Receptor for Advanced Glycation End-Products. Am J Respir Crit Care Med 2021, 204 (3), 359–362.","presentateur":"ALLARDET-SERVENT Jerome"},{"id":99585,"num":"A34637AT","reference":"FC-251","title":"Optimum time to initiate awake prone positioning in SARS-CoV-2 pneumonia to improve outcome","formatedAuthors":"Ahlem TRIFI (1), Lynda MASSEOUD (1), Asma OUHIBI (1), Bedis TLILI (1), Cyrine ABDENNEBI (1), Foued DALY (1), Yosr TOUIL (1), Sami ABDELLATIF (1), Salah BEN LAKHAL (1)
(1) Medical intensive care unit, teaching hospital la Rabta, Faculty of Medicine of Tunis, Tunis, TUNISIE","contentIntroduction":"In patients with hypoxemic SARS-CoV-2 pneumonia, it becomes conventional that awake prone positioning (APP) under high nasal flow cannula (HNFC) improves oxygenation, reduces the need for mechanical ventilation (MV) and improve survival. And the earlier it was, the better outcome would be. But what about the optimum time to initiate APP in this kind of patients?\n Our aim was to determine the best time to initiate APP in hypoxemic SARS-CoV-2 pneumonia.","contentPatientsMethods":"Prospective and analytical study including adult patients with acute hypoxemic confirmed SARS-CoV-2 pneumonia who received APP for at least one hour from HNFC administration. APP initiation times and all outcome parameters (primary: survival and secondary: MV use and ROX index) were recorded and compared. The optimum delay to initiate APP was determined by the ROC curve.","contentResultats":"We included 40 patients (31 male) with, a median age of 57 years, median SOFA of 4, and median signs onset of 11 days, Of them, 32,5% obese, 37,5% have hypertension, 32,5% diabetic and 5% fully vaccinated. The intubation and death rates were respectively 45% and 50%. The median time to initiate APP from HNFC was 7,5 hours [0-48] with extremes at 0 and 192 H. The number of APP sessions per day was at 2 [1-3] for a median duration at 4 hours [2-6]. The time of APP from HNFC was significantly lower in survivors (n=20) versus non survivors (n=20) (14 [6-18] versus 48 [20-72], p=0,033 respectively). Similarly, it was significantly lower in patients who not required MV (n=22) (12,5 [4-14,75] versus 33 [18-72], p=0,044 respectively). The best cutoff of APP from HNFC we showed predictor of survival was at 15 hours with AUC/ROC=0,725 ([0,563-0,887], p=0,015), sensitivity at 65% and specificity at 85%. Initiating APP from HNFC within 15 hours has less performance to predict the use of MV (AUC/ROC=0,664 ([0,491-0,837], p=0,07), sensitivity at 55,6% and specificity at 78%). \n Attached table displays the comparisons of the outcome’s variables according to the cutoff of APP from HNFC that we found (early: < 15H (n=25) versus late: > 15H (n=15)). In the early APP group, survival was significantly better and MV use was lower. MV duration and ICU stay tended to be lower in this same group with an average gain of 36 hours.","contentDiscussion":"","contentConclusion":"In patients with hypoxemic SARS-CoV-2 pneumonia, the positioning on APP within 15 hours of HNFC improved survival and reduced the need of MV.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"MASSEOUD Lynda"},{"id":99586,"num":"A34601YP","reference":"FC-252","title":"Awake Prone Positioning for Non-intubated Patients with COVID-19 Related Acute Hypoxemic Respiratory Failure: A Systematic Review and Meta-Analysis","formatedAuthors":"Yonatan PEREZ (1), Jie LI (2), Jian LUO (3), Ivan PAVLOV (4), Wei TAN (6), Oriol ROCA (7), Elsa TAVERNIER (17), Aileen KHARAT (8), Bairbre MACNICHOLAS (9), Miguel IBARRA-ESTRADA (10), David VINES (2), Nicholas A. BOSCH (11), Garrett RAMPON (12), Steven Q. SIMPSON (12), Allan J. WALKEY (11), Michael FRALICK (13), Amol VERMA (14), Fahad RAZAK (14), Tim HARRIS (15), John G. LAFFEY (9), Claude GUÉRIN (16), Stephan EHRMANN (5)
(1) Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, FRANCE ; (2) Department of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, ETATS-UNIS ; (3) Respiratory Medicine Unit and Oxford NIHR Biomedical Research Centre, NDM Experimental Medicine, University of Oxford, Oxford, ROYAUME-UNI ; (4) Department of Emergency Medicine, Hôpital de Verdun, Montréal, CANADA ; (5) CHRU de Tours, Médecine Intensive Réanimation, Tours, FRANCE ; (6) Department of respiratory and critical care medicine, the First Affiliated Hospital, China Medical University, Shenyang, CHINE ; (7) Servei de Medicina Intensiva, Hospital Universitari Vall d’Hebron, Barcelone, ESPAGNE ; (8) Department of respiratory medicine, Geneva University Hospital, Genève, SUISSE ; (9) Department of Anesthesia and Intensive Care Medicine, Galway University Hospitals and School of Medicine, National University of Ireland, Galway, IRLANDE ; (10) Unidad de terapia Intensiva, Hospital Civil Fray Antonio Alcalde, Guadalajara, MEXIQUE ; (11) Boston University School of Medicine and Boston Medical Center, Boston, ETATS-UNIS ; (12) University of Kansas Medical Center, Kansas City, ETATS-UNIS ; (13) Department of Medicine, Sinai Health System, and Department of Medicine, University of Toronto, Toronto, CANADA ; (14) Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Unity Health Toronto, and Department of Medicine, University of Toronto, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, CANADA ; (15) Hamad Medical Corporation, Doha, QATAR ; (16) Médecine Intensive Réanimation, Hôpital Edouard Herriot, Lyon, FRANCE ; (17) Clinical Investigation Center, INSERM 1415, CHRU de Tours, Tours, FRANCE","contentIntroduction":"Since the early phases of COVID-19 pandemic, prone positioning of non-intubated patients has been broadly utilized for patients with acute hypoxemic respiratory failure (AHRF) related to COVID-19. This intervention showed improvement of oxygenation. But the results of randomized controlled studies (RCTs) about intubation and mortality are contradictory. We aimed to assess the efficacy and safety of awake prone positioning (APP) including in relevant subpopulations.","contentPatientsMethods":"We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. Two independent groups of investigators searched MEDLINE,\n Embase, PubMed, Web of Science, Scopus, MedRxiv, BioRxiv, Google Scholar, and ClinicalTrials.gov for eligible studies from January 1st, 2020 to November 8th, 2021. RCTs comparing APP (intervention group) and supine position (control group) for non-intubated patients hospitalized for COVID-19 related AHRF were included. Random-effects meta-analysis was used to pool individual studies. Observational studies of APP comprising a control group were also included as a sensitivity analysis. Primary outcome was reported need for intubation. Secondary outcomes included: reported all-cause mortality, need for escalating respiratory support, Intensive Care Unit (ICU) admission, ICU length of stay, hospital length of stay and safety outcomes.","contentResultats":"29 studies were included, with 10 RCTs comprising 1,985 patients and 19 non-RCTs totalizing 2,669 patients. In 10 RCTs, compared to the supine position, APP significantly reduced the need for intubation in the overall population (risk ratio [RR] 0,84, 95% confidence interval [CI95] 0,72 to 0,97) (figure 2A). In the subgroup analysis, this significant reduction of intubation was observed in the studies with patients on advanced respiratory support (high-flow nasal cannula or noninvasive ventilation) at enrolment (RR 0,83, CI95 0,71 to 0,97), and those enrolled in ICU settings (RR 0,83, CI95 0,71 to 0,97) but not in patients receiving conventional oxygen therapy or enrolled in general wards. APP did not significantly reduce mortality (RR 1,00, CI95 0,70 to 1,44) (figure 2B). APP did not demonstrate a benefit on need for escalation of respiratory support, ICU admission, ICU and hospital length of stay. No serious adverse events associated with APP (in particular, cardiac arrest) were reported.","contentDiscussion":"","contentConclusion":"This systematic review and meta-analysis found that in patients with COVID-19 related AHRF, APP reduced the need for intubation, particularly in those patients requiring advanced respiratory support at enrollment and in those enrolled in the ICU but did not demonstrate a benefit on mortality and others secondary outcomes.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PEREZ Yonatan"},{"id":99587,"num":"A34613TW","reference":"FC-253","title":"Extended prone positioning duration for COVID-related ARDS: a retrospective study","formatedAuthors":"Thaïs WALTER (1), Noémie ZUCMAN (1), Jimmy MULLAERT (2,4), Ingrid THIRY (1), Coralie GERNEZ (1), Damien ROUX (1,3), Jean-Damien RICARD (1,4)
(1) AP-HP, Hôpital Louis Mourier, DMU ESPRIT, Service de Médecine Intensive Réanimation, Colombes, FRANCE ; (2) Department of Epidemiology, Biostatistics and Clinical Research, AP-HP, Hôpital Bichat, Paris, FRANCE ; (3) Université Paris Cité, Institut Necker-Enfants Malades, INSERM U1151, CNRS UMR 8253, Paris, FRANCE ; (4) Université Paris Cité, UMR1137 IAME, INSERM, Paris, FRANCE","contentIntroduction":"During the COVID-19 pandemic, many more patients were turned prone than before, resulting in a considerable increase in workload. Whether extending duration of prone position may be beneficial has received little attention. We report here benefits and detriments of a strategy of extended prone positioning duration for COVID-19 related acute respiratory distress syndrome (ARDS).","contentPatientsMethods":"Retrospective, monocentric, study on intensive care unit patients with COVID-19 related ARDS who have been treated with at least one session of prone positioning session of duration greater or equal to 24 hours. When prone positioning sessions were initiated, patients were kept prone for a period that covered two nights. They were put back in the supine position around 11 AM the morning following the second night. Demographic data, data regarding the incidence of pressure injury and ventilation parameters were collected retrospectively on medical and nurse files of charts.","contentResultats":"For the 81 patients included, the median duration of prone positioning sessions was 39 hours (interquartile range (IQR) 34-42) and patients benefited from a median of 2 sessions (IQR 1-4). The cumulated incidence of grade ≥ II pressure injuries was 26% (95%CI 17-37) and 2.5% (95%CI 0.3-8.8) for stages III/IV pressure injuries. This increased duration was associated with additional increase in oxygenation after 16 hours with the PaO2/FiO2 ratio increasing from 150 mmHg (IQR 121-196) at H+16 to 162 mmHg (IQR 124-221) before being turned back to supine (p = 0.017) (Fig 1). For 213 (94%) of prone positioning sessions, patients were turned over to supine position during daytime, ie between 9 AM and 6 PM. In comparison, had prone positioning sessions lasted strictly for 16 hours, half of them (n=117, 52%) would have required a turning back to supine between 6 PM and 9 AM, i.e. during night shifts.","contentDiscussion":"In an ancillary study of an international randomized trial evaluating prone positioning in ARDS, a cumulated incidence of 25% of patients presenting for the first time a pressure injury of stage ≥ II between day 1 and ICU discharge was reported(1). This is in line with our findings of a cumulated incidence of 26%.","contentConclusion":"Given the number of patients requiring prone position because of COVID-19-related ARDS, our results may have significant impact on both intensive care unit staffing and organizational issues, and could improve ventilatory parameters.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"for the Proseva trial group, Girard R, Baboi L, Ayzac L, Richard J-C, Guérin C. The impact of patient positioning on pressure ulcers in patients with severe ARDS: results from a multicentre randomised controlled trial on prone positioning. Intensive Care","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"WALTER Thaïs"},{"id":99588,"num":"A34522KN","reference":"FC-254","title":"Impact of prone position on renal function in the critical covid19 patient","formatedAuthors":"Anass MOUNIR (1), Karima NAANANI (1), Sara CHABBAR (1), Ayman ELOUDGHIRI (1), Rachid CHERKAB (1), Chafik EL KETTANI ELHAMDI (1), Lahoucine BARROU (1)
(1) Réanimation Pavillon 17, CHU IBNROCHD, Casablanca, MAROC","contentIntroduction":"Prone position [PP] is a method that has been widely used in the management of severe ARDS in COVID19. The increase in intra-abdominal pressure during the prone position can promote dysfunction of certain organs, particularly the kidney. The aim of our study was to assess the impact of prone position on renal function by analyzing the variations of intra abdominal Pressure.","contentPatientsMethods":"A prospective study of 56 patients with critical COVID19 under mechanical ventilation over a period of 6 months [September2020-March2021].\n PP was adopted in all our patients, with intravesical pressure [IVP] measurements before and during PP.\n In addition to the measurement of hourly diuresis, we performed the determination of renal aggression markers, urea and plasma creatinine levels before, during and after PP.","contentResultats":"The mean age was 61.8 years. A clear male predominance was observed.\n The prone position allowed an improvement of the patients` oxygenation after the first PP session and after 3 sessions.\n We detected an increase in IVP in the prone position, which exceeded 12mmHg and rose even higher to 60mmHg or 68mmHg in some patients.\n Renal aggression was observed in 32 patients from the first session of PP. 26 patients progressed to AKI, which represents 46.4% of our study population, with recourse to extrarenal depuration in 12 out of 26 patients.\n Univariate analysis allowed us to show that obesity [OR: 1.24, Pvalue: 0.004], with a high abdominal perimeter [OR: 1.194, CI: 1.19-31.674, Pvalue: 0.009], and critical parenchymal damage >75% [OR: 3.203, CI: 1.049-9.811, Pvalue: 0.038] represent risk factors for progression to renal insufficiency. It was also shown that high intravesical pressure is significantly associated with renal failure [OR: 6.4, CI: 1.446-44.64, Pvalue: 0.002].","contentDiscussion":"The kidney is the most sensitive organ to increased IAP and is the first organ affected in case of intra abdominal pressure. However, to date, no study in the literature has concretely established predictive factors of the occurrence of acute renal failure in the patient placed in prone position, after a severe COVID19.","contentConclusion":"Our study allowed us to emphasize the value of prone positioning in the severe or critical Covid19 patient. However, the use of PP requires an understanding of the risks, including intra-abdominal pressure and the risk of renal failure.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"NAANANI Karima"},{"id":99589,"num":"A34350BP","reference":"FC-255","title":"Impact of Time-Controlled Adaptive Ventilation (TCAV) on hemodynamics in a swine ARDS model","formatedAuthors":"Benjamin PEQUIGNOT (1), Mickael LESCROART (1), Laurent BITKER (2), Héloise PINA (1), N’Guyen TRAN (1), Jean-Louis HEBERT (3), Jean-Christophe RICHARD (2), Bruno LEVY (1), Matthieu KOSZUTSKI (1)
(1) CHRU de Nancy, VandœUvre-Lès-Nancy, FRANCE ; (2) Hopital de la Croix Rousse, Lyon, FRANCE ; (3) Institut de Cardiologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, FRANCE","contentIntroduction":"The current standard of care of severe ARDS is based on low tidal volume (VT), at 6 mL/kg of predicted body weight, and a positive end expiratory pressure (PEEP). An alternative strategy could be the time-controlled adaptive ventilation (TCAV) strategy, i.e. a specific settings of airway pressure release ventilation (APRV) mode. Initially reported by Habashi et al, TCAV relies on delivering a CPAP phase, followed by a brief expiratory release phase (1). TCAV leads to an increase in intra thoracic pressures and could be associated with hemodynamic impairment. The objective of our study was to compare hemodynamics between TCAV and conventional protective ventilation in a porcine ARDS model.","contentPatientsMethods":"In ten pigs (63-73 kg) lung injury was induced by repeated saline lavages followed by 2 hours of injurious ventilation. The animals were then randomized into two groups: 1) Volume-controlled ventilation (VCV) with a VT of 6 mL/kg and PEEP adjusted to a plateau pressure of 28 to 30 cmH2O; 2) TCAV group with P-high set between 27-29 cmH2O, P-low at 0 cmH2O, T-low adjusted to terminate at 75% of the expiratory flow peak, and T-high at 3-4 seconds for I:E > 6:1.","contentResultats":"There was no difference between-group for arterial blood pressure, pulmonary blood pressure or cardiac output. No significant left ventricular inotropic or relaxation alteration was noticed under TCAV versus VCV. Both elastance and PaO2:FiO2 were consistent with a moderate to severe ARDS after a two-hour period of injuring ventilation. Levels of total PEEP were significantly higher in TCAV group. Driving pressure and elastance were significantly lower in the TCAV group than in VCV group in multivariate analysis.","contentDiscussion":"First, experimental ARDS induced significant hemodynamic changes mainly driven by hypoxemia-induced pulmonary vasoconstriction. Secondly, TCAV did not significantly impact systemic hemodynamics, despite of the increase in intrathoracic pressures. Thirdly, TCAV increased alveolar recruitment in this ARDS model. Concerning limitations : The study might have been underpowered to assess a clinically relevant effect of TCAV on hemodynamics. Improvement in elastance can be in relation with higher level of total PEEP and suggest alveolar recruitment but we did not perform any CT scan to verify this hypothesis. To finish, conventional protective group had a transpulmonary pressure above 15 cmH2O at all times of interest which may also explained effect observed on hemodynamics parameters.","contentConclusion":"No safety signal was observed for hemodynamic adverse events in the TCAV group in this double hit ARDS swine model.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Habashi NM. Other approaches to open-lung ventilation: airway pressure release ventilation. Crit Care Med. 2005;33:S228–S240. doi: 10.1097/01.CCM.0000155920.11893.37","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PEQUIGNOT Benjamin"},{"id":99590,"num":"A34509ml","reference":"FC-256","title":"Potential for Alveolar recruitment in Covid-19 related ARDS: evaluation by the Recruitment-to-Inflation Ratio (R/I) method","formatedAuthors":"Manel LAHMAR (1), Hedia BEN AHMED (1), Abir CHIHAOUI (1), Amir BEDHIAF (1), Zeineb HAMMOUDA (1), Fahmi DACHRAOUI (1), Fekri ABROUG (1), Lamia BESBES OUANNES (1)
(1) CHU fattouma bourguiba Monastir , Monastir , TUNISIE","contentIntroduction":"Optimizing alveolar recruitment by means of positive end-expiratory pressure (PEEP) is the cornerstone of ARDS ventilation. PEEP exposes nevertheless to alveolar distension, which is harmful in these patients. Hence, the actual effects of PEEP depend on the recruitment potential of the lung we should evaluate in every patient. Chen et al recently validated in non-Covid-19 ARDS an index (R/I) allowing bedside assessment of the potential for alveolar recruitment (or overdistension) ref 1 (Chen, Del Sorbo et al. 2020).Objective: To characterize by R/I ratio the recruitment potential in an ARDS-Covid19 cohort.","contentPatientsMethods":"a prospective study carried out between January and October 2021, including patients hospitalized consecutively for severe SDRACOVID-19 (PaO2/FiO2≤150 mmHg).All patients received a lung-protective ventilation. The R/I ratio was measured in the supine position and in the prone position. The threshold proposed by Chen et al (0.5) was used to identify high recruiters and low recruiters.","contentResultats":"23 patients were included. The median age was 62 years IQR [52-65], most patients were male (Sexe ratio (H/F) =1, 87). The main chest computed tomography findings were ground-glass opacities only 13 (56, 5%) or associated with consolidation 9 (39, 1%). High Recruiters had isolated ground glass in 72.7% of cases. Whereas, low recruiters had more ground glass associated with condensations in 54.5%. All patients received a lung-protective ventilation. VT median was 380 ml [360-400], median PEEP and median Pplat were respectively 14 cmH2O [10-15], 30 cmH2O [29-30].The median R/I index was 0.48 in supine and 0.65 in prone position. Eleven patients (47.8%) had recruitment potential (R/I≥0.5) while 12 (52.2%) had non-recruiting lungs. Median plateau pressure was 30 (with extremes ranging from 25 to 32cmH2O) and static compliance was 27 .","contentDiscussion":"","contentConclusion":"This study confirms the high frequency of ARDS with low recruitment potential in C-ARDS (Pan, Chen et al. 2020). This characteristic imposes a \"personalized\" ventilation based on the individual pulmonary mechanics properties.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Potential for Lung Recruitment Estimated by the Recruitment-to-Inflation Ratio in Acute Respiratory Distress Syndrome. A Clinical Trial Lu Chen 1 2 3, Lorenzo Del Sorbo 3 4, Domenico L Grieco 5, Detajin Junhasavasdikul 6, Nuttapol Rittayamai 7, Ibrahim So","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAHMAR Manel"},{"id":99591,"num":"A34512ml","reference":"FC-257","title":"Evaluation of alveolar recruitment in Covid-related ARDS: Multiple P-V curves vs Recruitment/Inflation (R/I) index","formatedAuthors":"Manel LAHMAR (1)
(1) CHU fattouma bourguiba Monastir , Monastir , TUNISIE","contentIntroduction":"PV curves have allowed a better understanding of the pathophysiology of ARDS and remain a reference for evaluating the potential for alveolar recruitment. Chen and al recently validated an index (R/I) using the “Single breath maneuver” technique in ARDS. This index assesses the potential for alveolar recruitment (or inflation) at the patient's bedside reference 1 (Chen, Del Sorbo et al. 2020).Both methods give an estimate of the magnitude of lung volume recruited. We conducted this study to compare estimated lung recruitment provided by these two methods.","contentPatientsMethods":"Prospective study conducted in 26 patients with covid ARDS mechanically ventilated in prone position. Two PEEP levels were studied, and EELV was measured at both levels, with the difference (ΔEELV)) reflecting PEEPinduced lung volume changes. Alveolar recruitment was measured using multiple pressure-volume (PV) curves (Extend respirator, Taema, France), and compared to the estimation made by the new index (R/I) . High and Low recruiters were separated based on median estimated recruited lung volume (Recestim). Estimated and measured recruitments were compared using Spearman correlation and Bland-Altman method.","contentResultats":"the median age was 63 years IQR [52-66], with no difference between the groups. Median recruited lung volume (Rec mes) measured by the technique of P-V curves was 227 ml [IQR :182-364]. By “ Single breath maneuver ” technique, the median volume recruited (Rec mes) was 410ml [295-506]. The median index (R/I) in Low recruiters was 0.46 [0.33-0.71] vs 0.66 [0.57-0.89] in high recruiters. The ΔEELV and Recestim was higher in high recruiters than in low recruiters.\n Recruited volume measured by “Single breath maneuver” and the PV curves method were strongly correlated (biais=79 ,95%CI : -98.7 ; 211.8). The concordance of both methods is reported in the figure1.","contentDiscussion":"","contentConclusion":"bedside evaluation of lung recruitment can be performed by simple clinical tool such as single breath manoeuver with acceptable bias.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Potential for Lung Recruitment Estimated by the Recruitment-to-Inflation Ratio in Acute Respiratory Distress Syndrome. A Clinical Trial Lu Chen 1 2 3, Lorenzo Del Sorbo 3 4, Domenico L Grieco 5, Detajin Junhasavasdikul 6, Nuttapol Rittayamai 7, Ibrahim So","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"LAHMAR Manel"},{"id":99592,"num":"A34320CG","reference":"FC-258","title":"Prone position during veno-venous extracorporeal membrane oxygenation in COVID-19 ARDS","formatedAuthors":"Laura TEXTORIS (1), Ines GRAGUEB-CHATTI (1), Bobot MICKAEL (1,2), Florence DAVIET (1), Mathieu THEPENIER (1), Estelle PILARCZYK (1), Saida SALMI (1), Camille PINGLIS (1), Sabine VALERA (1), Celine SANZ (1), Matthieu AMALRIC (1), Aude SYLVESTRE (1), Noemie PERES (1,3), Fabien ARGENONE (1,4), Claire STEIN (1), Clotilde BAILLEUL (1), Jean-Marie FOREL (1), Antoine ROCH (1), Sami HRAIECH (1), Laurent PAPAZIAN (1), Christophe GUERVILLY (1)
(1) Médecine Intensive Réanimation, CHU Hôpital Nord, AP-HM, Marseille, FRANCE ; (2) Centre de Néphrologie et Transplantation Rénale, CHU de la Conception, AP-HM, Marseille, FRANCE ; (3) Réanimation, Hôpital Sainte Musse, Toulon, FRANCE ; (4) Réanimation, Centre Hospitalier de Digne-les-Bains, Digne-Les-Bains, FRANCE","contentIntroduction":"Veno-venous Extra-Corporeal Membrane Oxygenation (vv-ECMO) has been extensively used for severe Acute Respiratory Distress Syndrome (ARDS) related to COVID-19 in case of prone position (PP) failure. A recent meta-analysis on observational studies suggests to continue PP while on vv-ECMO both in classical ARDS and COVID-19 related ARDS (CARDS) 1. PP could mitigates ventilator induced lung injuries even during low volume, low pressure ventilation facilitated by vv-ECMO. Objectives were to investigate respiratory mechanics and physiological effects of PP and to assess safety in severe CARDS patients during vv-ECMO.","contentPatientsMethods":"We performed a prospective observational cohort studies in COVID-19 patients supported by vv-ECMO in the ECMO center of a tertiary university hospital in Marseille. All patients were deeply sedated and received continuous infusion of neuromuscular blockers during PP. We compared respiratory mechanics, ECMO and ventilator settings, gas exchanges and hemodynamics in supine, start of PP, end of PP and back to supine with analysis of variance.","contentResultats":"We included 25 patients with a range of 2 to 17 PP totalizing 120 PP in the COVID-19 cohort. All patients had PP before ECMO consideration. ECMO was indicated after a median (IQR) of 5 (1-7) days of mechanical ventilation with PaO2: FiO2 of 68 (50-74) mmHg. ECMO weaning was achieved in 72 %. ICU and hospital survival was 52%. First PP was performed after 2 (1-3) days of ECMO during 16 hours. At baseline, very low tidal volume of 2.5 (2-3.5) ml/Kg/PBW with a PEEP of 12 (10-15) cm H2O targeting a plateau pressure of 25 (21-26) cm H2O were used. We did not found significant changes in respiratory mechanics and gas exchanges during or after first PP. In particular, respiratory system compliance remains low at 11 (10-17) before and 11 (9-17) cm H2O after PP. PaO2 was respectively 75 (61-81), 78 (69-85), 77 (70-83) and 77 (67-89) mmHg at baseline supine, start of PP, end of PP and back to supine, (p=0.33) at a constant ECMO blood flow (3.8 to 4 L/min) and membrane lung fraction of 1. Concerning safety, we did not observed severe adverse events during PP. Only 3 (2.5%) of PP were interrupted for respiratory or hemodynamics worsening.","contentDiscussion":"","contentConclusion":"PP is feasible and safe during vv-ECMO for severe CARDS. Potentials benefits could be explained by mechanism not identified in this study.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1223","session":"FLASH COM - Decubitus ventral et recrutement alvéolaire","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Papazian L, Schmidt M, Hajage D,et al. Effect of prone positioning on survival in adult patients receiving ve","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GUERVILLY Christophe"},{"id":99593,"num":"A34686RA","reference":"FC-259","title":"High-flow nasal oxygen therapy decrease the risk of mortality and the use of invasive mechanical ventilation in patients with severe SARS-CoV-2 pneumonia? A retrospective and comparative study of 265 cases","formatedAuthors":"Rajae ALKOUH (1), Abdelilah EL RHALETE (1), Manal MERBOUH (1), Ghizlane EL AIDOUNI (1), Samia BERRICHI (1), Salma TAOUIHAR (1), Fatima Zahra AFTISS (1), Houssam BKIYAR (1), Naima ABDA (1), Brahim HOUSNI (1)
(1) CHU Mohammed VI OUJDA , Oujda, MAROC","contentIntroduction":"To evaluate the efficacy of high-flow nasal oxygen HFNO versus non-invasive ventilation in COVID-19.","contentPatientsMethods":"This is a retrospective and comparative study conducted over a period of 10 months from March 2020 to December 2020 and involving 600 patients hospitalized in the intensive care unit of the CHU Mohammed VI of Oujda for the management of acute respiratory failure caused by COVID-19.","contentResultats":"Out of 600 patients with acute respiratory failure, 265 patients were included in the analyses. 162 (61.10%) patients were treated with HFNO, the intubation rate was 49.7% (80 patients out of 162) of which 63 died intubated (78.8%). Concerning the 82 non-intubated patients, only 16 died (19.8%).The total number of patients who received NIV was 71 (26.8%), 33 (46.5%) required mechanical ventilation. In-hospital mortality in patients treated with NIV was 100%.The difference in mortality outcome between the two groups was significantly (P < 0.0001) reduced in HFNO.","contentDiscussion":"","contentConclusion":"Treatment with high-flow oxygen improved survival in patients with acute hypoxemic respiratory failure compared with noninvasive ventilation, although no difference was observed in intubation rate.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Goyal P., Choi J.J., Pinheiro L.C., Schenck E.J., Chen R., Jabri A., Satlin M.J., Campion T.R., Jr., Nahid M., Ringel J.B., Hoffman K.L., Alshak M.N., Li H.A., Wehmeyer G.T., Rajan M., Reshetnyak E., Hupert N., Horn E.M., Martinez F.J., Gulick R.M. Clinic","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Leung C.C.H., Joynt G.M., Gomersall C.D., Wong W.T., Lee A., Ling L., Chan P.K.S., Lui P.C.W., Tsoi P.C.Y., Ling C.M., Hui M. Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumon","presentateur":"ALKOUH Rajae"},{"id":99594,"num":"A34744AB","reference":"FC-260","title":"Predicting factors for the failure of high flow nasal cannula (HFNC) in COVID-19 related Acute Respiratory Distress Syndrome (ARDS)","formatedAuthors":"Amir BEDHIAFI (1), Radhouane TOUMI (1,2), Iyed MATOUK (1), Nabil BOUGUEZZI (1), Marwa ZGHIDI (1,2), Khaoula MEDDEB (1,2), Imen BEN SAIDA (1,2), Mohamed BOUSSARSA (1,2)
(1) Medical intensive Care Unit, Farhat Hached University Hospital, Sousse, TUNISIE ; (2) Research Laboratory N° LR12SP09. Heart Failure. Farhat Hached University Hospital, University of Sousse, Sousse, TUNISIE","contentIntroduction":"HFNC in widely used as a first line respiratory support in severe to critical COVID-19 pneumonia. We aimed to investigate factors associated with failure of HFNC in the management of COVID19 related ARDS (CARDS).","contentPatientsMethods":"In this single-center study conducted in a 20-bed adult-ICU, consecutive admission for CARDS were screened for eligibility. Patients who underwent invasive mechanical ventilation (IMV) within 6 hours upon admission were excluded. We collected clinical data and lab findings from admission until HFNC weaning or intubation which defined HFNC failure. ROX index was recorded at H0, H2, H6, H12 and H24. We also measured PF ratio evolution, monitored FiO2 and respiratory rate (RR). High work of breathing (HWOB) was defined as a respiratory rate (RR) above 30 cpm and/or excessive accessory muscle use.","contentResultats":"230 patients were included until August 2021. 61.5% (n=141) men, median aged 62 [IQR 53-70] with SAPS-II at 28±8, PF ratio 132±63.8 under FiO2 0.72±0.23 on admission. 42% hypertension, 41.3% diabetes and 32.2% obesity. 55.2% (n=127) successfully weaned from HFNC with a survival rate at 18% among those ongoing IMV.\n HFNC failure was associated to: higher SAPS II (32±7.4 vs 24.7±7, p<0.001) obesity (47% vs 27%, p=0.001) and compromised oxygenation parameters on admission: high FiO2 (0.84±0.17 vs 0.6±0.21), RR (29.7±4.6 vs 25.6±3.7, p=0.001), presence of HWOB (67% versus 17%, p<0.001) and lower PF-ratio (101±48.6 vs 157.5±64.2, p<0.001). Sub-group analysis following PF-ratio showed higher success rate in mild-to-moderate compared to severe ARDS (85.7%, 65.2% and 27.6% respectively, p=0.001). ROX-index was significant at H6, H12 and H24 to predict HFNC failure. ROC analysis showed a higher specificity and sensitivity for H12 and H24 (AUC 0.906 IC 95% [0,864-0.948] and 0.944 IC 95% [0,908-0.981] respectively, p<0.001) [Figure 1].\n 30% (n=69) required non-invasive positive pressure ventilation at day 2.1±1.3 alternating with HFNC and had higher failure rate (88.4% vs 26.1%, p<0.001). 87% (n=200) performed pronging position while under HFNC with a higher associated success rate (58% vs 33%, p=0.01).","contentDiscussion":"","contentConclusion":"HFNC appears to be safer in mild-to-moderate CARDS especially when combined to proning. ROX index, PF-ratio and WOB monitoring are reliable predictors for HFNC failure. More studies might be needed to confirm this results.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BEDHIAFI Amir"},{"id":99595,"num":"A34340JC","reference":"FC-261","title":"Comparison of three noninvasive oxygenation strategies on outcomes in critically ill patients admitted for Covid-19 pneumonia: a retrospective multicenter cohort study.","formatedAuthors":"Jonathan CHELLY (1), Louis-Marie COUPRY (2), Ly Van VONG (3), Touffik KAMEL (4), Medhi MARZOUK (5), Nicolas TERZI (6), Cedric BRUEL (7), Aurélie AUTRET (1), Aude GARNERO (1), Jean-Michel ARNAL (1)
(1) Centre Hospitalier Intercommunal Toulon La Seyne sur Mer, Toulon, FRANCE ; (2) Groupe Hospitalier Sud Ile de France, Melun, FRANCE ; (3) Grand Hôpital de l'Est Francilien, Jossigny, FRANCE ; (4) Centre Hospitalier Régional d'Orléans, Orléans, FRANCE ; (5) Centre Hospitalier de Béthune, Béthune, FRANCE ; (6) Centre Hospitalier Universitaire de Grenoble, Grenoble, FRANCE ; (7) Hôpital Saint-Joseph, Paris, FRANCE","contentIntroduction":"Noninvasive respiratory support (NIRS) is recommended as the first line to reduce the need of invasive mechanical ventilation (MV) and its associated complications and high mortality in patients affected by Covid-19 pneumonia admitted in the intensive care unit (ICU). However, the optimal first-line noninvasive strategy to support oxygenation and ventilation is still debated.","contentPatientsMethods":"We conducted a retrospective multicenter study in 7 French ICUs, including all consecutive adults admitted between July and December 2020 with a documented SARS-CoV-2 acute respiratory failure (PaO2/FiO2 < 300 mmHg), and treated either with high-flow nasal therapy (HFNT) alone, or noninvasive ventilation combined or not with HFNT (NIV) or continuous positive airway pressure combined or not with HFNT (CPAP). Patients who received both NIV and CPAP and those who were intubated within the 12 first hours after ICU admission were excluded. The primary outcome was the NIRS failure, defined as the need of endotracheal intubation or death in the ICU without endotracheal intubation.","contentResultats":"Among the 355 included patients, 160 (45%) were treated with HFNT alone, 115 (32%) with NIV and 80 (22%) with CPAP. NIV and CPAP were combined with HFNT in 97 (84%), and 79 (99%) patients, respectively. Median age (67 [58–75]), body mass index (29 [25–33] kg/m2), SAPS-2 (42 [32–57]) and PaO2/FiO2 (130 [93–167]) on admission were similar between groups whereas Charlson comorbidity index was lower when HFNT was used alone compared to NIV and CPAP. The primary outcome occurred in 158 (45%) patients with a statistical difference between HFNT alone, NIV, and CPAP groups (41%, 59%, and 31%, respectively; p<0.001). Compared to patients who were treated with HFNT alone or NIV, those who were treated with CPAP had a lower incidence of the primary outcome on day 28 after ICU admission (p=0.002) whereas ICU mortality was similar between groups (p=0.20).","contentDiscussion":"","contentConclusion":"Among patients admitted for Covid-19 pneumonia in ICU and treated with NIRS, outcome seems to differ according to the strategy. More studies are warranted to compare such NIRS and identify the optimal treatment.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"CHELLY Jonathan"},{"id":99596,"num":"A34598FE","reference":"FC-262","title":"Using CPAP in patients with SARS-CoV-2 hypoxemic pneumonia outside intensive care unit","formatedAuthors":"Fatma ESSAFI (1,2), Salma ESSAGHAYER (1,2), Iheb GLENZA (1,2), Imen TALIK (1,2), Khaoula BEN ISMAIL (1,2), Moez KADDOUR (1,2), Aida BAYOUDH (3), Ilhem FESSI (3), Tahani JERBI (4), Mariem CHKIRBENE (4), Takoua MERHABENE (1,2)
(1) Intensive care unit, Regional Zaghouan’s Hospital, Zaghouan, TUNISIE ; (2) Faculty of medicine of Tunis, Tunis El-Manar university, Tunis, TUNISIE ; (3) Pneumology department, Regional Zaghouan’s Hospital, Zaghouan, TUNISIE ; (4) Pharmacy department, Regional Zaghouan’s Hospital, Zaghouan, TUNISIE","contentIntroduction":"Use of continuous positive airway pressure (CPAP) has been recommended in the management of patients with acute respiratory failure related to COVID-19 infection. However, its impact on mortality, length of hospital stay and the occurrence of complications have not been elucidated especially when delivered outside of a traditional critical care environment. Through this study, we propose to investigate the role of CPAP in the management of hypoxemic pneumonia due to SARS-CoV-2 in a pneumology department.","contentPatientsMethods":"We reviewed retrospectively all data of consecutive confirmed COVID-19 patients receiving CPAP for the treatment of respiratory failure secondary to COVID-19. Were enrolled Patients admitted from 1st June to 31th August 2021 on the pneumology department of the regional hospital of Zaghouan, Tunisia. Were collected Epidemiological, clinical and paraclinical data, complications and outcome.","contentResultats":"During the study period, 205 patients were hospitalized, 65 of them required CPAP (31.7%). Median age was 64 years [34-87]. A clear male predominance was noted with sex ratio1.5. Chronic heart disease, obesity, Diabetes mellitus, and chronic obstructive pulmonary disease were the most common comorbidities (55.4%; 38.5%, 27.7% and 10% respectively). Tobacco consumption was noted in 20% of patients. On admission, all patients had acute respiratory failure. Initial symptoms are essentially fever, nonproductive cough, dyspnea and gastrointestinal symptoms. The median time of symptoms at admission was 8.2±3.6 days [1-20]. On initial examination, pulse air saturation ranged was 83.5±8% [57-93] and oxygen requirements were 12±6 liters/min [6-30]. Four patients (6.2%) presented with acute hypertensive heart failure, requiring diuretic therapy. The predominant pattern of abnormality observed in chest CT was ground-glass opacification in 55 patients (84.6%), bilateral opacities in 27 patients (41.5%) and crazy paving in 17 patients (26.2%). Mean lung extension was estimated at 58±20 %.\n Mean duration of CPAP ventilation was 4±3.2 days [1-18]. it was associated to high flow oxygen therapy in 43 patients and to conventional oxygen therapy in 22 patients. Awake prone position was applied in 39% of patients.\n only one patient had developed care-related pneumonia. Mean length of hospital stay was 7.2±4.8 days [1-21]. In hospital mortality was 32%. The outcome was favorable in 58 patients (66%).","contentDiscussion":"","contentConclusion":"CPAP represents a feasible and potentially efficient option for the treatment of respiratory failure in COVID-19. It can be delivered safely outside the traditional critical care, thus relieving pressure on critical care beds.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ESSAGHAYER Salma"},{"id":99597,"num":"A34723JA","reference":"FC-263","title":"Predictive factors of high flow nasal cannula failure in critically ill COVID-19 patients admitted in a medical ICU for acute respiratory failure","formatedAuthors":"Hend ZORGATI (1), Dhouha BEN BRAIEK (1), Rania HIDRI (1), Oussama SAADAOUI (1), Safa BEN MANSOUR (1), Imen MIGHRI (1), Arsalene DOUZI (1), Chaima KAABI (1), Oumaima GHABI (1), Asma AZAZA (1), Rahma BEN JAZIA (2), Amani KACEM (2), Imen KHARRAT (2), Jihene AYACHI (1)
(1) Service Réanimation Médicale, Hôpital Universitaire Ibn El Jazzar , Kairouan, TUNISIE ; (2) Service Pneumologie, Hôpital Universitaire Ibn El Jazzar , Kairouan, TUNISIE","contentIntroduction":"High-Flow Nasal Cannula (HFNC) therapy appears to be effective to treat hypoxemic acute respiratory failure (ARF) patients during the outbreak of Coronavirus disease (COVID-19). However, there are few data about factors associated with HFNC failure in COVID-19 patients. Aim :To determine predictive factors associated with HNFC failure in COVID-19 patients admitted in medical intensive care unit (ICU) for ARF.","contentPatientsMethods":"A one year observational, retrospective study performed from January 1st, 2021 to December 31st, 2021 in a 9-bed medical ICU at university hospital including adult patients admitted for hypoxemic ARF pneumonia secondary to SARS-CoV-2 and received HFNC on admission. Medical patients’ charts were reviewed to collect demographic characteristics, underling diseases, severity at admission, clinical course and outcomes.\n Univariate and multivariate analysis were used to identify predictive factors associated with HFNC failure. HFNC failure was defined as mechanical ventilation (invasive or noninvasive) use.","contentResultats":"From 146 patients admitted for severe COVID-19 pneumonia, 128 (87.7%) received HFNC. Main characteristics were mean age, 51.05 ±14.8 years; male predominance, 75(58.6%) and 100(78.1%) had at least one comorbidity. Median BMI and P/F ratio were : 31[28-32]kg/m2 and 92.75[69-118.5]. Median SAPS II, SOFA and Charlson score were respectively : 23 [16-29] ; 2[2-4] and 1[0-2]. HFNC parameters were median Flow at 52.5[45-60]l/min and median FiO2 at 90[70-100] %.The median ROX index at H1 and H24 were respectively at 4.26[3.3-5.9] and 6.2[4.5-8.4]. Awake prone position was performed in 105(82%) of cases. HFNC failed in 43 (33.6%) patients, among them 32 (25%) were initially managed with noninvasive ventilation (NIV) with mortality rate at 35.2%. Univariate analysis identified the following factors for HNFC success and failure: elderly patient (7(8.2%) vs 17(39.5%), p=0.000) ; cardiovascular comorbidity (7(8.2%) vs 9(20.9%), p=0.04) ; Charlson index (0.5[0-1] vs 2[1-3], p=0.000) ; SAPSII (19[13-24] vs 29[24-34.25],p=0.000); SOFA (2[1-4] vs 4[2-8.5], p=0.000) ; prone position (71(83.5%) vs 29(67.4%), p=0.038); ROX index at H1(5[3.8-6.04] vs 3.45[3-4.57], p=0.000); ROX index at H24 (7.73[5.75-9.05] vs 4.2[3.8-5.6], p=0.000) and ROX index at day 6 (9.6±3.5 vs 4.5±1.4, p=0.000). The multivariate logistic regression model identified ROX index at day 6 (OR, 0.3; 95% CI, [0.14-0.67]; p=0.03) as a predictor factor of HFNC success.","contentDiscussion":"","contentConclusion":"ROX index at day 6 was the best predictor of HFNC failure in COVID-19 patients with hypoxemic AFR admitted in ICU.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"HIDRI Rania"},{"id":99598,"num":"A34684IA","reference":"FC-264","title":"Non-invasive ventilation in critically ill COVID-19 patients","formatedAuthors":"Ilef ALILA (1), Sana KHARRAT (1), Malek HAFDHI (1), Najeh BACCOUCH (1), Salma JERBI (1), Mabrouk BAHLOUL (1), Mounir BOUAZIZ (1)
(1) hopital Habib Bourguiba Sfax, Sfax, TUNISIE","contentIntroduction":"Non-invasive ventilation (NIV) was recommended for acute respiratory distress syndrome. A potential role for NIV to delay or avoid invasive mechanical ventilation (IMV) has emerged during the COVID-19 pandemic (1).\n The aim of this study was to explore the role of non-invasive ventilation in prediction of outcome in critically ill COVID-19 patients.","contentPatientsMethods":"We conducted a retrospective study in a medical ICU over a period of 16 months [September 2020-December 2021] including patients with SARS-COV2 infection. The impact of non-invasive ventilation on complications and patient outcome was investigated.","contentResultats":"During the study period, 586 patients were included with a mean age of 59.5 ± 14.7 and a gender ratio of 1.6. The median SAPSII and SOFA score were respectively of 29 ± 14.8 and 4 ± 2.6. Most patients had comorbidities, including hypertension (36 %), obesity (32.1%) and diabetes (36.2%).\n 419 (71.5%) patients had severe acute respiratory distress syndrome (ARDS). Median ICU length of stay was 6 IQR [3-10] days and overall mortality was of 49 % (287patients).378 patients (64.5 %) needed NIV oxygenation. Of those who received NIV, 214 (57%) required IMV versus 50 (24%) of those not. Patients who received NIV developed more infections during their hospitalizations than those in the No-NIV group (220 (58%) vs 44(21%); p<0.001.). Mortality was higher in patients receiving NIV (238 (63%) Vs 49 (23%), P<0.001). Length of stay was significantly longer in NIV group (table I).","contentDiscussion":"","contentConclusion":"The use of NIV can predict morbidity and mortality in critically ill COVID-19 patients.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"(1)Matt Birch, Charlotte Toms, Harish Shankar Kumar, Claire Calderwood, Adam Ainley: Late Breaking Abstract - Non-invasive ventilation for COVID-19 at a North East London NHS Trust: a retrospective analysis","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"ALILA Ilef"},{"id":99599,"num":"A34483TP","reference":"FC-265","title":"Comparison of two respiratory support strategies in critically ill patients admitted for Covid-19: a retrospective monocentric cohort study.","formatedAuthors":"Timothé PAUL (1), Jonathan CHELLY (1), Jean-Michel ARNAL (1), Aude GARNERO (1)
(1) Centre Hospitalier Intercommunal Toulon La Seyne sur Mer – Hôpital Sainte Musse, Toulon, France., Toulon, FRANCE","contentIntroduction":"Respiratory support for patients suffering for COVID-19 pneumonia in intensive care unit (ICU) is mandatory. During the first months of the outbreak, clinical trials have demonstrated that many oxygen strategies could delay intubation.However the outcomes between early and late intubation were not established in this particular kind of pneumonia.","contentPatientsMethods":"We conducted a retrospective observational monocentric study in a French ICU including all consecutive adults with a documented SARS-CoV-2 acute respiratory failure (PaO2/FiO2 < 300 mmHg). Two periods were compared: the first included all patient admitted between February 2020 and June 2020, and an early intubation strategy was applied; the second period included all patients admitted between August 2020 and December 2020, and a non-invasive respiratory support strategy, using High-flow nasal canula, continuous positive airway pressure (CPAP), awake prone positioning and late intubation was applied. The primary outcome was the ICU length of stay. The secondary outcomes were complications, rate and duration of invasive ventilation and mortality in ICU.","contentResultats":"47 patients were included in the first period and 96 in the second period. First period was associated with a longer ICU stay compared to the second period (11.00 [8.25-19.50] days versus 8.00 [4.75-14.25] days; p = 0,028). First period was associated with longer duration of respiratory support and higher intubation rate compared to the second (9[9-16] days versus 7[3-14] days; p=0.338; 68% versus 25%; p<0,001, respectively). The first period was associated with more complications such as hypotension, tracheotomy, critical illness neuromyopathy, ventilator associated pneumonia and thromboembolic complications whereas barotrauma and venovenous extracorporeal membrane oxygenation were no different between periods. ICU mortality was similar between periods (P=0.814).","contentDiscussion":"","contentConclusion":"In this study, non-invasive respiratory support strategy with late intubation is associated with a shorter length of stay for critically ill patient with COVID-19 compared to an early intubation strategy. A non-invasive strategy would allow a better resource management of the healthcare system during the outbreak. Other studies are warranted to evaluate the impact on the long-term mortality.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"PAUL Timothé"},{"id":99600,"num":"A34736ER","reference":"FC-266","title":"The effect on proning depends on the interface used: NRB vs HFNC vs NVI","formatedAuthors":"Ilyes SALLEMI (1,2), Emna RACHDI (1,2), Fatma JARRYA (1,2), Amira JAMOUSSI (1,2), Samia AYED (1,2), Mohamed BESBES (1,2), Jalila BEN KHELIL (1,2)
(1) Hopital Abderrahman Mami, Ariana, TUNISIE ; (2) Faculté de Médecine de Tunis, Tunis, 0","contentIntroduction":"Since the PROSEVA study in 2013, prone positioning (PP) is a postural maneuver recommended early in the management of acute respiratory distress syndrome (ARDS) in patients who remain hypoxic on mechanical ventilation. \n With the increase in the incidence of ARDS over the last 2 years in relation to the COVID-19 pandemic, PP has been attempted in non-intubated patients to improve oxygenation.\n Several studies have been carried out in non-intubated patients admitted to an intensive care unit for the management of ARDS. We proposed to compare the effect of different oxygenation interfaces during PP wakefulness.","contentPatientsMethods":"Between March and May 2021, 117 adult patients were admitted to the medical intensive care unit of MAMI hospital for severe to critical COVID-19 . Among them, 56 patients underwent at least one PP session.\n During the first 24 hours, PP sessions of at least 30 minutes were performed with change of oxygenation interface each time ranging from a non-rebreather mask (NRB) to a high flow nasal canula (HFNC) then to non-invasive ventilation (NIV) last. Blood gas was performed before and 20 minutes after each session under the same oxygenation parameters. The response to PP was defined by an increase in the PaO2/FiO2 ratio of 20%.","contentResultats":"Fifty six patients had a PP session. They were male in 56.9 % of cases with a men age of 55 years and mean BMI of 28.06. At admission, they had severe ARDS in 46.4% and mild in 42.9%. \n PP session was performed in conventional oxygen therapy in fifty-one patients. The difference in PaO2/FiO2 ratio before and after the session was on average 14 mmHg [-96, 138mmHg] with no statistically significant difference (p = 0.09). The response to PP was heterogeneous, with 25.5% (n=13) responders.\n Under HFNC, the mean delta PaO2/FiO2 was 5.6 mmHg (-67, 125 mmHg) for all 32 patients, 21 were responders (65%). PP under NIV was tolerated by only 41 patients who had a mean PaO2/FiO2 response of 17.6 mmHg (-120, 197 mmHg) with no statistically significant difference (p = 0.07). Eighteen of them (43.9%) were responders.\n In contrast to NIV, the PP response under NRB decreased the need for oro-tracheal intubation (p=0.03). PP significantly improved survival of patients under NRB and HFNC (p=0.04 for NRB and p=0.03 for HFNC).","contentDiscussion":"","contentConclusion":"Although the benefice of PP in intubated patient is demonstrated, awake PP needs more evidence by conducting more prospective multicentric studies with prolonged proning sessions.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1224","session":"FLASH COM - Oxygène à haut débit humidifié dans le COVID-19","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SALLEMI Ilyes"},{"id":99601,"num":"A34467HA","reference":"FC-267","title":"Factors associated with mortality in hospitalized Covid-19 patients","formatedAuthors":"Hend ALLOUCHE (1), Jihene GUISSOUMA (1), Insaf TRABELSI (1), Ichrak BACHA (1), Mohamed SAMET (1), Habib BRAHMI (1), Hatem GHADHOUNE (1)
(1) Hôpital universitaire Habib Bougatfa de Bizerte, Bizerte, TUNISIE","contentIntroduction":"The emergence of the novel Covid-19 has caused millions of deaths worldwide. This study aimed to identify factors that are associated with mortality in hospitalized Covid-19 patients.","contentPatientsMethods":"This was a retrospective, observational cohort study conducted on adults patients hospitalized in intensive care unit with confirmed Covid-19 infection, between January 2021 and September 2021. Demographics, clinical pattern, laboratory and radiological investigations associated with increased rate of mortality were analysed.","contentResultats":"Of the 140 patients included, mortality rate was 70.3%. Main factors associated with mortality among our cohort were age over 60 years (p<0.001), history of hypertension (p=0.001) and chronic kidney failure (p=0.04). Also, elevated inflammatory markers and severity scores were associated with higher mortality. Patients placed on mechanical ventilation and those who had nosocomial infections had an increased rate of mortality (p<0.001 and p=0.01 respectively). Greater lung involvement and obesity were not associated with higher mortality in our study.","contentDiscussion":"","contentConclusion":"In our study several factors were associated with mortality as advanced age, hypertension, chronic kidney failure, elevated inflammatory markers and severity scores, mechanical ventilation and nosocomial infections.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"GHADHOUNE Hatem"},{"id":99602,"num":"A34444OS","reference":"FC-268","title":"Is procalcitonin useful to diagnose early bacterial pulmonary co-infection among intubated patients with SARS-CoV-2 or influenza pneumonia ?","formatedAuthors":"Ouriel SAURA (1), Anahita ROUZÉ (1), Ignacio MARTIN-LOECHES (2), Pedro POVOA (3), Makris DEMOSTHENES (4), Antonio ARTIGAS (5), Julien LABREUCHE (1), Saad NSEIR (1)
(1) CHU Lille, Lille, FRANCE ; (2) Multidisciplinary Intensive Care Research Organization (MICRO), St James Hospital, Dublin, IRLANDE ; (3) Hospital de Sao Francisco Xavier , Lisbone, PORTUGAL ; (4) University Hospital of Larissa, Larissa, GRECE ; (5) Corporacion Sanitaria Universitaria Parc Tauli, CIBER Enferme dades Respiratorias, Sabadell, ESPAGNE","contentIntroduction":"A large proportion of critically ill patients admitted for severe coronavirus disease 2019 (COVID-19) receive empirical antimicrobial treatment upon admission. Recent studies have reported a low rate (<10%) of early bacterial co-infection among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, and significantly lower compared to patients with influenza pneumonia (1). We aimed to determine the performance of procalcitonin (PCT) to diagnose early bacterial pulmonary co-infection within 48 hours after intubation in critically ill patients with SARS-CoV-2 or influenza pneumonia.","contentPatientsMethods":"We performed a post hoc analysis of data from the multicenter retrospective coVAPid cohort study. Adult patients receiving invasive mechanical ventilation for at least 48 hours for SARS-CoV-2 (first wave in Europe) or influenza pneumonia (2016-2020 admissions), and with at least one PCT measurement within 48h after intubation were considered for the present analysis. Bacterial pulmonary co-infection was defined by bacterial isolation, within 48h after intubation, in endotracheal aspirates, bronchoalveolar lavage, or blood cultures, or a positive pneumococcal or legionella urinary antigen test. We assessed the performance of PCT to diagnose co-infection using a receiver operating characteristic (ROC) curve analysis, and the association of PCT with patient’s co-infection status and 28-day mortality after pre-specified adjustment (age, sex, IGS2, and disease group) using a multivariable logistic regression model.","contentResultats":"615 patients were included (349 in SARS-CoV-2, and 266 in influenza groups). The area under the ROC curve (AUC) was 0.60 (95%CI 0.48 to 0.71) and 0.66 (95%CI 0.58 to 0.73) for the diagnosis of co-infection in SARS-CoV-2 and influenza groups, respectively. PCT was significantly associated with co-infection in patients with influenza pneumonia (adjusted odds ratio (OR) per log increase in level of PCT 1.29 (95%CI 1.13 to 1.48)), but not in patients with SARS-CoV-2 pneumonia (adjusted OR 1.26 (95%CI 0.98 to 1.61)) (Figure 1). Conversely, adjusted OR for 28-day mortality per log increase of PCT was 1.03 (95%CI 0.89 to 1.19) and 1.41 (95%CI 1.16 to 1.71) in influenza and SARS-CoV-2 groups respectively, suggesting that PCT was a better indicator of disease severity than co-infection among severe COVID-19 patients.","contentDiscussion":"","contentConclusion":"We reported a low diagnostic value of PCT to detect bacterial co-infection within 48 hours after intubation in patients with severe SARS-CoV-2 or influenza pneumonia. PCT level was significantly associated with 28-day mortality among severe COVID-19 patients.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Rouze A, Martin-Loeches I, Povoa P et al. coVAPid study group. Early Bacterial Identification Among Intubated Patients with COVID-19 or Influenza Pneumonia: A European Multicenter Comparative Cohort Study. Am J Respir Crit Care Med. 2021 May 26;204(5):546","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"SAURA Ouriel"},{"id":99603,"num":"A34590Dd","reference":"FC-269","title":"Retrospective comparison of COVID-19 and seasonal influenza mortality and outcomes in the intensive care units of a French university hospital","formatedAuthors":"Donatien DE MARIGNAN (1), Charles-Hervé VACHERON (1), Florence ADER (2), Maxime LECOCQ (1), Jean Christophe RICHARD (2), Laurent ARGAUD (3), Julien BOHE (1), Vincent PIRIOU (1), Bernard ALLAOUCHICHE (1), Arnaud FRIGGERI (1), Florent WALLET (1)
(1) CHU LYON SUD - PIERRE BENITE (RHONE), Pierre Benite, FRANCE ; (2) CHU de la CROIX ROUSSE - LYON , Lyon, FRANCE ; (3) CHU EDOUARD HERRIOT - LYON, Lyon, FRANCE","contentIntroduction":"Severe COVID-19 has become a major worldwide health concern since its appearance at the end of 2019 in China. Commonalities have been suggested with seasonal influenza. Our objective was to evaluate the intrinsic mortality and burden of SARS-CoV-2 and seasonal influenza pneumonia in intensive care units (ICU) in a university hospital in a major city in France.","contentPatientsMethods":"We conducted a retrospective study in six ICUs in a single institution. Consecutive patients admitted to an ICU with SARS-CoV-2 pneumonia from February 27 to April 4, 2020 (COVID-19 group) and seasonal influenza pneumonia from November 1, 2015 to April 30, 2019 (INFLUENZA group) were screened. A total of 350 patients were included in the COVID-19 group (18 refused to consent) and 325 in the INFLUENZA group (1 refused to consent). Diagnosis was confirmed by RT-PCR. Follow-up was completed on April 1, 2021. \n We collected demographic characteristics, comorbidities, long-term medications at ICU admission, and evaluated difference in 90-day adjusted-mortality between the COVID-19 and INFLUENZA group using a multivariable Cox proportional hazards model.","contentResultats":"COVID-19 patients were younger, mostly men, and had a higher median BMI, and comorbidities, including immunosuppressive condition or respiratory history were less frequent. In univariate analysis, no significant differences were observed between the 2 groups regarding in-ICU mortality, 30, 60 and 90-day mortality. After Cox modelling adjusted on age, sex, BMI, cancer, sepsis-related organ failure assessment (SOFA) score, simplified acute physiology (SAPS II) score, chronic obstructive pulmonary disease and myocardial infarction, the probability of death associated with COVID-19 was significantly higher in comparison to seasonal influenza (HR 1.57, CI95% [1.14; 2.17]; p=0.006). The clinical course and morbidity profile of both groups was markedly different; COVID-19 patients had less severe illness at admission (SAPS II score, 37 [28-48] vs. 48 [39-61], p<0.001, and SOFA score, 4 [2-8] vs. 8 [5-11], p<0.001), but the disease was more severe considering ICU length of stay, duration of mechanical ventilation, PEEP level, and prone positioning requirement.","contentDiscussion":"","contentConclusion":"After ICU admission, COVID-19 was associated with an increased risk of death compared to seasonal influenza. Patient characteristics, clinical course, and morbidity profile of these diseases is markedly different. \n Patients with seasonal influenza die because of their comorbidities while COVID-19 patients die because of COVID-19 pneumonia.\n \n This study has been accepted for publication after reviewing in \"European Journal of Anaesthesiology\"","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"DE MARIGNAN Donatien"},{"id":99604,"num":"A34714is","reference":"FC-270","title":"Covid-19 and pregnancy: what we should know?","formatedAuthors":"Ines SDIRI (1), Nizar FITOUHI (1), Amira DRIDI (1), Sana DORGHAM (1), Sonia OUERGHI (1), Tahar MESTIRI (1)
(1) hopital ariana abderahmen memi, Sfax, TUNISIE","contentIntroduction":"Physiological changes during pregnancy have a significant impact on the immune system, respiratory system, cardiovascular function, and coagulation. The impact of SARS-CoV-2 in pregnancy remains to be determined(1). Our study aim to describe the characteristics of COVID19 infections in per partum patients before vaccine authorization(2)","contentPatientsMethods":"A retrospective and descriptive study of 9 months duration carried out in the COVID intensive care unit including all per partum patients with COVID 19 pneumonia between March 2021 and September, 2021. All pregnant or immediate postpartum women hospitalized for SARS-CoV2 infection were included. Demographic, clinical, Para clinical, therapeutic and evolutionary data were collected. The primary endpoint was maternal mortality. Two groups were identified: Group 1 = Survivors and Group 2 = Deceased. The differences in data of the patients were evaluated.","contentResultats":"During the study period, we collected 17 patients. The incidence of COVID19 infection in per partum patients was 5% in our series. All patients were admitted postpartum (75% by caesarean section). The median age was 31(25-38) years. The comorbidities were chronic respiratory deficient (3 patients) and hypothyroidism (3). The mean BMI was 28±3 kg/m². All patients were unvaccinated. Seven were multiparous. The mean gestational age was 27±6 weeks of amenorrhea. The mean PaO2/FiO2 ratio at admission was 98±35 mmHg. All patients admitted to the ICU were in respiratory distress. Severe ARDS was observed in 11 patients (64%). 47% patients received high-flow nasal oxygen therapy and one patient was under mechanical ventilation at admission. Chest CT scans were performed in 15 patients (88,2%). An involvement highest of 50% was observed in 13 patients (76.4%). All patients received anticoagulation and corticosteroid therapy. Invasive mechanical ventilation (IMV) was required in 5 cases. 5 patients (29,4%) needed the use of vasoactive amines. The occurrence of nosocomial infection was found in 7 patients, 2 patients were developed acute kidney injury and one required hemodialysis, 6 patients presented a thromboembolic event. Tocilizumab was prescribed for 2 patients and one patient was discharged for ECMO.The median length of hospitalization was 9±7 days and the mortality rate was 46,3%. Univariate analysis of the 2 groups showed that use of IMV (G1:5(100%)% vs. G2:0(0%); p= 0.001) and nosocomial infection (G1:4(80%)% vs. G2:0(0%); p= 0.01) were associated with excess mortality.","contentDiscussion":"","contentConclusion":"Currently data didn't show significant relationship between COVID-19 severity and pregnancy and there is no strong evidence that covid-19 lead to adverse pregnancy outcome, but further studies are needed.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Pregnancy and COVID-19: pharmacologic considerations .(20 févr 2022).","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"Horm Mol Biol Clin Investig. 11 févr 2021;42","presentateur":"SDIRI Ines"},{"id":99605,"num":"A34727sb","reference":"FC-271","title":"Pregnant women and COVID 19 in intensive care: series of 18 cases","formatedAuthors":"Soulef BOUSBIA (1), Abdelkader DJEBBARI (1), Rachid KRABA (1), Mohamed Amine BENHAMED (1)
(1) CHU D'ORAN, Oran, ALGERIE","contentIntroduction":"In pregnant women, the symptoms of COVID-19 are similar to those of the general population in most cases. That said, like any population at risk, more serious symptoms may appear such as pneumonia or ARDS. The objective is to define the clinical, biological and therapeutic characteristics as well as the management of a series of pregnant women with COVID-19.","contentPatientsMethods":"This is a retrospective and descriptive study which collected 18 pregnant patients affected by the Coronavirus SARS-CoV-2 in the intensive care unit between July 20 and September 15, 2021\n \n We included parturients requiring a high flow of polypneic oxygen at 30 cycles / min with an SPO2 < 92% Were excluded the parturients without sign of respiratory distress","contentResultats":"The average age is 31 years old. Six patients were followed for a chronic disease. Gestational diabetes was the most common comorbidity. Contact with a suspected or confirmed case of COVID-19 was identified in 10 patients. The average incubation period for the virus was 6.89 days. The average term of pregnancy was 33.36 weeks of amenorrhea. The preferred way of delivery was caesarean section. The most frequently reported symptoms were fever in all patients, dyspnoea in all patients. 16 patients were taken care of in medical intensive care for an array of acute respiratory distress syndrome (ARDS) after cesarean section. 4 patients were put on nasal high-flow oxygen therapy: Optiflow with recourse to mechanical ventilation after 48 hours. In the 14 other cases, mechanical ventilation was indicated after the caesarean section, symptomatic treatment and antibiotic therapy had been started upon admission in all the patients. 5 patients were de-ventilated after 12 days of ventilation, 5 patients died of massive pulmonary embolism, 5 of the patients died of pulmonary superinfection, 4 patients died of severe hypoxia.","contentDiscussion":"","contentConclusion":"This is a global pandemic with high mortality worldwide; Published studies on SARS-COV-19 infection during pregnancy are few; they are no more at risk of being infected with the coronavirus, but the disease can have significant consequences on the course of their pregnancy. They are also more prone to severe forms of Covid-19.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"BOUSBIA Soulef"},{"id":99606,"num":"A34678NJ","reference":"FC-272","title":"Pregnant women and COVID19: hospitalization in intensive care unit predictive factors","formatedAuthors":"Nour Zayneb JAAFAR (1), Ines FATHALLAH (1), Nadia KOURAICHI (1)
(1) Université de Tunis - El Manar ,Hôpital régional de Ben Arous , Tunis , TUNISIE","contentIntroduction":"Pregnant women, a vulnerable population, have not been spared from the COVID-19 pandemic. In the absence of vaccination, severe forms and acute respiratory distress syndromes(ARDS) have been reported.","contentPatientsMethods":"We reviewed all data of confirmed COVID-19 pregnant patients hospitalized in our Hospital ICU and in gynecology’s department between September 2020 and September 2021 for the management of acute pneumopathy due to Sars-Cov-2. Infection was confirmed by RT-PCR, rapid test, or chest CT scan. Were collected epidemiological, clinical and paraclinical data and outcomes.","contentResultats":"Thirty-six patients were included with a mean age of 33 ± 5 years and a mean term of pregnancy of 34 ± 4 weeks. The median consultation time after the onset of symptoms was 3.5 days [1;7] and the median hospital stay was 4 days [1;7].\n Among 36 pregnant women ,no one of the patients was vaccinated against SARS-Cov-2. Eleven patients(34%) were hospitalized in the ICU.\n Symptoms were dominated by respiratory signs, cough and dyspnoea ,in respectively 21 (65%) and 15 (47%) patients.\n The different ventilatory supports were: single oxygen therapy (50%), high concentration mask (34%), high flow oxygen therapy (12.5%), and invasive ventilation (16%).\n Predictive factors for hospitalization in ICU were: dyspnea [p<10-3 RR=5.25 95% CI [2.174; 12.679]], oxygen uptake [p=0.01 RR=3.81 95%CI[1.737; 8.393]], delay before consultation > 4.5 days [p=0.021 RR=3.897 95% CI [1.267; 11,991]] and a period of hospitalization before admission in ICU >5.5 days [p=0.002 RR=6.33 95% CI [1.608;24.939]].\n Among the six patients who had invasive ventilation ,tracheotomy was practiced at three patients(27%).\n The ICU stay was complicated by septic shock in 4 patients (36%)and a thromboembolic disease in 4 patients (36%).\n The median length of ICU stay was 11[5.54] days. The ICU mortality was high around 18% againt an overall mortality of 6%.","contentDiscussion":"","contentConclusion":"Mortality was significant in our study : 34% of patients required hospitalization in ICU with an overall mortality of 6%.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"flash com","exposant":null,"bibliographie":null,"idSession":"1225","session":"FLASH COM - COVID-19 : obstétrique, co infections","theme":"Respiratoire","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"JAAFAR Nour Zayneb"},{"id":99607,"num":"A34591SA","reference":"FC-273","title":"Prevalence and outcome of SARS-COV2 bacterial coinfection","formatedAuthors":"Racha GHABARA (1), Samia AYED (1), Lilya DEBBICHE (1), Emna RACHDI (1), Fatma JARRAYA (1), Amira JAMOUSSI (1), Jalila BEN KHELIL (1)
(1) HOPITAL ABDERRAHMEN MAMI, Ariana, TUNISIE","contentIntroduction":"The rate of SARS-CoV2 bacterial coinfection is poorly defined. The decision to administer antibiotics early in the course of SARS-CoV2 infection depends on the likelihood of bacterial coinfection. The purpose of this study was to examine the prevalence of SARS-COV2 bacterial co-infection on admission and to investigate the impact on outcome.","contentPatientsMethods":"This was a retrospective study carried within a medical intensive care unit in Abderrahmen Mami Hospital between marsh 2020 and august 2021. All consecutive patients admitted for severe COVID-19 were enrolled. Bacterial co-infection was systematically investigated on intensive care unit (ICU) admission. A comparative study was conducted between the coinfection group and a matched non coinfection- group based on age, body mass index, severity scores and PaO2/FiO2 ratio on admission.","contentResultats":"During the study period, 544 patients were hospitalized in the intensive care unit for severe COVID-19. Fifty-four per cent of patients received antibiotics before ICU admission (n=292) including amoxicillin- clavulanic acid association (n=85), azithromycine (n=129) and levofloxacine (n=29). Only 49 patients showed bacterial coinfection on admission (9%). Most involved pathogens were: enterobacteracae (Klebsiella n=15, Enterobacter cloacae n=2, Serratia Marcesses n=2), Staphylococcus aureus methicilline sensitive (n=5) and non-fermentative Gram-negative bacilli such as Pseudomonas aeruginosa (n=6). Twenty-one patients with bacterial coinfection received antibiotics prioir to the ICU admission (43%).\n No statistical difference was found in the univariate analysis comparing the coinfection group and the matched non-coinfection group. Only SGOT and SGPT levels were significatively higher in the coinfection group (p=0,05 and p=0,03 respectively). Need for mechanical ventilation and mortality did not differ significatively between the two groups (p=0,371 and p=0,469 respectively).","contentDiscussion":"","contentConclusion":"Bacterial coinfection rate in patients admitted with severe SARS-CoV2 infection is low. No significative difference was found between coinfected and non coinfected group. 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(1) CHU DE LIEGE, LIEGE, BELGIQUE ; (2) Marie-Curie Hospital, Charleroi, BELGIQUE ; (3) University Hospital, Gent, BELGIQUE ; (4) CHU Erasme, Bruxelles, BELGIQUE ; (5) Godinne University Hospital, Namur, BELGIQUE ; (6) Delta General Hospital, Roeselare, BELGIQUE ; (7) CHU Anvers, Anvers, BELGIQUE ; (8) Imelda General Hospital, Bonheiden , BELGIQUE ; (9) CHU Bruxelles, Jette, BELGIQUE ; (10) CHWAPI Hospital, Tournai, BELGIQUE ; (11) Groeninge General Hospital, Courtrai, BELGIQUE ; (12) Sint Blasius General Hospital, Dendermonde, BELGIQUE ; (13) CHR Citadelle, Liège, BELGIQUE ; (14) OLV General Hospital, Aalst, BELGIQUE ; (15) Saint Pierre General Hospital, Ottignies, BELGIQUE ; (16) Saint Pierre University Hospital, Brussels, BELGIQUE ; (17) Saint Luc University Hospital, Bruxelles, BELGIQUE ; (18) University Hospital Leuven, Leuven, BELGIQUE ; (19) Red Cross, Mechelen, BELGIQUE ; (20) Red Cross, Suarlée, BELGIQUE","contentIntroduction":"Passive immunization with plasma collected from convalescent patients has been used to treat COVID-19. Few trials used plasma with documented high titers of neutralizing antibodies and minimal data are available from patients with COVID-19 requiring MV. \n Our hypothesis was that passive immunization with plasma collected from convalescents and high titers of neutralizing antibodies may reduce mortality in patients with COVID-19 induced pneumonia and ARF requiring MV.","contentPatientsMethods":"We randomly assigned patients with COVID-19 requiring MV for less than 5 days in a 1:1 ratio to receive either convalescent plasma with a neutralizing antibodies titer at least 1/320 or standard of care. Stratification by the time from tracheal intubation to inclusion (less or more than 48 hours). The primary outcome was day-28 mortality. 17 centers. Plasmas were delivered by the Belgian Red Cross. Number of patients to include for a 40% expected mortality in controls and 13.5 % crude reduction: n = 500. Interim analysis every 100 patients. The rules to recommend trial interruption by the independent committee (DSMB) have been predefined and published. Only the DSMB had access to the results of the interim analyses.","contentResultats":"475 patients were included in the trial between October 2020 and March 2022. Due to the absence of new case for more than one month, the steering committee decided to close the recruitment period on April 9, 2022. At the time of abstract submission, the following data are available : out of 475 patients, 72% have been included in strata < 48 h and 28% between 48h and 5 days. Median [IQR]: age = 64 [55-71] years, BMI = 30 [26-35] kg/m², APACHE 2 = 13 [9-18] points, CRP = 120 [56-190] mg/L, time from hospital admission = 5 [2-7] days. Use of hydroxychloroquine = 0.2%, remdesivir = 6.7 %, anti-IL-6 = 3.5 %, steroids = 95.0 %. Day 28 mortality = 39 %. Use of ECMO = 20 %, vasopressors = 80 %, RRT = 15 %. No adverse event was directly attributed to the plasma. The DSMB analyzed the results after 100, 200, 300 et 400 patients and recommended to complete the trial at each step. The statistical analysis of most endpoints will be available for presentation at the Congress.","contentDiscussion":"","contentConclusion":"This trial is the only one to test convalescent plasma which high titer of neutralizing antibodies against SARS-CoV-2 is documented in patients with COVID-19 induced pneumonia and ARF requiring MV.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 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(1) Université et Centre Hospitalier Universitaire de Tours, Tours, FRANCE ; (2) Université et Hospices Civils de Strasbourg, Strasbourg, FRANCE ; (3) Université et Centre Hospitalier Universitaire de Dijon, Dijon, FRANCE ; (4) Centre Hospitalier Régional d'Orléans, Orléans, FRANCE ; (5) Université Paris Cité - Nord et Assistance Publique Hôpitaux de Paris, Colombe, FRANCE ; (6) Centre Hospitalier Nord - Franche-Comté, Trévenans, FRANCE ; (7) Université et Centre Hospitalier Universitaire de Nantes, Nantes, FRANCE ; (8) Université Paris Saclay et Assistance Publique Hôpitaux de Paris, Garches, FRANCE ; (9) Centre Hospitalier d'Argenteuil, Argenteuil, FRANCE ; (10) Université et Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, FRANCE ; (11) Sorbonne Université et Assistance Publique Hôpitaux de Paris, Paris, FRANCE ; (12) Centre Hospitalier de la Roche sur Yon, La Roche sur Yon, FRANCE ; (13) Université et Centre Hospitalier Universitaire de Poitiers, Poitiers, FRANCE ; (14) Université Paris Cité - Centre et Assistance Publique Hôpitaux de Paris, Paris, FRANCE ; (15) Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, FRANCE ; (16) Université et Centre Hospitalier Universitaire de Limoges, Limoges, FRANCE ; (17) Centre Hospitalier Régional de Metz-Thionville, Metz, FRANCE ; (18) Université et Centre Hospitalier Universitaire de Nancy, Nancy, FRANCE ; (19) Centre Hospitalier du Mans, Le Mans, FRANCE ; (20) Service de Santé des Armées, Brest, FRANCE ; (21) Université d'Aix-Marseille et Assistance Publique Hôpitaux de Marseille, Marseille, FRANCE ; (22) Centre Hospitalier de Montauban, Montauban, FRANCE ; (23) Université et Centre Hospitalier Universitaire de Brest, Brest, FRANCE ; (24) Centre Hospitalier d'Aulnay sous Bois, Aulnay sous Bois, FRANCE ; (25) Centre Hospitalier de Bourg en Bresse, Bourg en Bresse, FRANCE ; (26) Université et Centre Hospitalier Universitaire de Caen, Caen, FRANCE ; (27) Université et Centre Hospitalier Universitaire de Grenoble, Grenoble, FRANCE ; (28) Université et Centre Hospitalier Universitaire de Rennes, Rennes, FRANCE ; (29) Centre Hospitalier de Saint-Malo, Saint-Malo, FRANCE ; (30) Université et Centre Hospitalier Universitaire de Lille, Lille, FRANCE ; (31) Centre Hospitalier d'Angoulême, Angoulême, FRANCE ; (32) CRICS-TriGGERSep network, Strasbourg (coordination), FRANCE","contentIntroduction":"Prednisone shortens time to clinical stability and length of hospital stay in patients admitted for non-severe community-acquired pneumonia (ref.1). In patients admitted to critical care with severe community-acquired pneumonia , some meta-analyses suggest that corticosteroids may reduce mortality (ref.2), but they are based on only 6 trials and fewer than 400 patients. The aim of the CAPE COD study was to confirm a survival gain in these patients.","contentPatientsMethods":"Patients admitted to the ICU for ommunity-acquired pneumonia with severity criterion (mechanically ventilated and/or PaO2/FiO2","contentResultats":"The trial was planned to include 1200 patients, with two interim analyses. The data safety and monitoring board recommended discontinuation of the study after the second analysis. 800 patients were randomized in 32 French centers, of which 795 were included in the main analysis (sex ratio 2.3, mean age 65.8 years, 353 mechanically ventilated at inclusion, including 177 invasively, mean PaO2/FiO2 154, mean SAPSII 39.2). At day 28, mortality was 25/400 (6.3%) in the hydrocortisone group and 47/395 (11.9%) in the placebo group, difference of proportions -5.6% [95%CI: -9.6%; -1.7%], p=0.0055. At day 90, mortality was 36/388 (9.3%) in the hydrocortisone group and 57/389 (14.7%) in the placebo group (18 missing data), difference of proportions -5.4% [95%CI: -9.9%; -0.8%], p=0.02.","contentDiscussion":"","contentConclusion":"This multicenter, double-blind, placebo-controlled trial shows a reduction in mortality at day 28 and day 90 in patients admitted to intensive care with severe community-acquired pneumonia and receiving hydrocortisone.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"communication orale","exposant":null,"bibliographie":null,"idSession":"886","session":"Session Hot topics","theme":"","motsCles":null,"abstractGuid":null,"contentInfoSupp":"Blum CA et al. 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(1) CHU de Poitiers, Poitiers, FRANCE ; (2) CHU Dijon-Bourgogne, Dijon, FRANCE ; (3) Hopital Nord Franche-Comte, Montbelliard, FRANCE ; (4) CH du Mans, Le Mans, FRANCE ; (5) CHRU Tours, Tours, FRANCE ; (6) CHU de Rennes, Rennes, FRANCE ; (7) Hôpitaux Universitaires de Strasbourg, Strasbourg, FRANCE ; (8) CH de Cholet, Cholet, FRANCE ; (9) CHU de Caen, Caen, FRANCE ; (10) GHR Mulhouse Sud-Alsace, Mulhouse, FRANCE ; (11) Groupe Hospitalier Sud de la Réunion, Saint Pierre, FRANCE ; (12) CH de Bourg-en-Bresse, Bourg-en-Bresse, FRANCE ; (13) CH de Dieppe, Dieppe, FRANCE ; (14) Groupe Hospitalier Universitaire APHP-Sorbonne Université, Paris, FRANCE ; (15) Groupement Hospitalier Nord-Dauphiné, Bourgoin-Jallieu, FRANCE ; (16) CHU Grenoble Alpes, Grenoble , FRANCE ; (17) Hôpital Saint-Joseph Saint-Luc, Lyon, FRANCE ; (18) CHU La Croix Rousse, Lyon, FRANCE ; (19) CHU Henri Mondor, Créteil, FRANCE ; (20) CH de Pau, Pau, FRANCE ; (21) CH Henri Mondor d’Aurillac, Aurillac, FRANCE ; (22) CH de Bourges, Bourges, FRANCE ; (23) CHU de Nantes, Nantes, FRANCE ; (24) CHU d'Angers, Angers, FRANCE ; (25) Groupe Hospitalier Bretagne Sud, Lorient, FRANCE ; (26) CHU de Brest, Brest, FRANCE ; (27) CHR d'Orléans, Orléans, FRANCE ; (28) INSERM, CIC-1402, Poitiers, FRANCE","contentIntroduction":"The benefit of high-flow nasal cannula oxygen (high-flow oxygen) in terms of intubation and mortality in patients with COVID-19-related respiratory failure is controversial.\n The obctive of the trial was to determine whether the use of high-flow oxygen, compared with standard oxygen, could reduce the rate of mortality at day 28 in patients with COVID-19-related respiratory failure admitted in intensive care unit (ICU).","contentPatientsMethods":"Patients:\n We report a multicenter randomized clinical trial conducted from January to December 2021 in 34 ICUs in France, among 711 patients with COVID-19-related respiratory failure and a ratio of partial pressure of arterial oxygen to fraction of inspired oxygen equal to or below 200 mm Hg were randomized. Final follow-up occurred on March 2022.\n \n Intervention: \n Patients were randomly assigned to receive high-flow oxygen or standard oxygen.\n \n Main outcomes: \n The primary outcome was mortality at day 28, and secondary outcomes included the proportion of patients requiring intubation, number of ventilator-free days at day 28, mortality at day 90, mortality and length of stay in ICU.","contentResultats":"Among the 783 randomized patients, 711 were included in the analysis (mean [SD] age, 61 [12] years; 214 women [30%]), 357 received high-flow oxygen and 354 standard oxygen .\n The mortality rate at day 28 was 10% (36/357) with high-flow oxygen and 11% (40/354) with standard oxygen group (absolute difference –1.2% [95% CI, –5.8 to 3.4]; P = .60).\n The intubation rate was significantly lower with high-flow oxygen than with standard oxygen, 45% (160/357) versus 53% (186/354), (absolute difference –7.7 [95% CI, –14.9 to –0.4], P = .04).\n The number of ventilator-free days at day 28 were 28 (95% CI, 11 to 28) with high-flow oxygen and 23 [95% CI, 10 to 28] with standard oxygen (P = .07).\n There was no difference in length of stay and mortality in intensive care unit, and in mortality up until day 90.","contentDiscussion":"","contentConclusion":"In COVID-19-related respiratory failure, treatment with high-flow oxygen did not result in a reduction in mortality as compared to standard oxygen. However, there was a significant difference in favor of high-flow oxygen in need for intubation.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"communication orale","exposant":null,"bibliographie":null,"idSession":"886","session":"Session Hot topics","theme":"","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"Frat Jean-Pierre"},{"id":99611,"num":"A35159AT","reference":"LBA-4","title":"Pressure-support ventilation versus T-piece for spontaneous breathing trials before extubation in patients at high-risk of reintubation.","formatedAuthors":"ARNAUD THILLE (1), ARNAUD GACOUIN (2), REMI COUDROY (1), EHRMANN STEPHAN (3), JEAN-PIERRE QUENOT (4), MAI-ANH NAY (5), CHRISTOPHE GUITTON (6), DAMIEN CONTOU (7), GUYLAINE LABRO (8), JEAN REIGNIER (9), GAEL PRADEL (10), GAETAN BEDUNEAU (11), LAURENCE DANGERS (12), JEAN DELLAMONICA (13), GWENAEL PRAT (14), GUILLAUME LACAVE (15), NICHOLAS SEDILLOT (16), NICOLAS TERZI (17), BEATRICE LA COMBE (18), JEAN-PAUL MIRA (19), ANTOINE ROMEN (20), MARIE-ANGE AZAIS (24), ANAHITA ROUZE (21), JEROME DEVAQUET (22), AGATHE DELBOVE (23), MARTIN DRES (25), JEREMY BOURENNE (26), ALEXANDRE LAUTRETTE (27), STEPHANIE RAGOT (28), JEAN-PIERRE FRAT (1)
(1) CHU DE POITIERS, POITIERS, FRANCE ; (2) CHU DE RENNES, RENNES, FRANCE ; (3) CHU DE TOURS, TOURS, FRANCE ; (4) CHU DIJON BOURGOGNE, DIJON, FRANCE ; (5) CH D'ORLEANS, ORLEANS, FRANCE ; (6) CH DU MANS, LE MANS, FRANCE ; (7) CH D'ARGENTEUIL, ARGENTEUIL, FRANCE ; (8) Groupe Hospitalier Régional Mulhouse Sud Alsace, MULHOUSE, FRANCE ; (9) CHU DE NANTES, NANTES, FRANCE ; (10) CH D'AURILLAC, AURILLAC, FRANCE ; (11) CHU DE ROUEN, ROUEN, FRANCE ; (12) CHU FELIX GUYON, SAINT DENIS DE LA REUNION, FRANCE ; (13) CHU DE NICE, NICE, FRANCE ; (14) CHU DE BREST, BREST, FRANCE ; (15) CH DE VERSAILLES, LE CHESNAY, FRANCE ; (16) CH DE BOURG EN BRESSE, BOURG EN BRESSE, FRANCE ; (17) CHU GRENOBLE ALPES, GRENOBLE, FRANCE ; (18) CH BRETAGNE SUD, LORIENT, FRANCE ; (19) HOPITAL COCHIN, PARIS, FRANCE ; (20) CH DE PAU, PAU, FRANCE ; (21) CHU DE LILLE, LILLE, FRANCE ; (22) HOPITAL FOCH, SURESNES, FRANCE ; (23) CH BRETAGNE ATLANTIQUE, VANNES, FRANCE ; (24) CH DEPARTEMENTAL DE VENDEE, LA ROCHE SUR YON, FRANCE ; (25) HOPITAL DE LA PITIE-SALPETRIERE, PARIS, FRANCE ; (26) CHU LA TIMONE 2, MARSEILLE, FRANCE ; (27) CENTRE JEAN PERRIN, UNICANCER, CLERMONT-FERRAND, FRANCE ; (28) UNIVERSITE DE POITIERS, POITIERS, FRANCE","contentIntroduction":"Guidelines recommend to systematically performing a spontaneous breathing trial (SBT) before extubation in ICUs. Patient effort is markedly lower during spontaneous breathing trials performed using pressure-support ventilation (PSV) than during T-piece, which could increase the risk of reintubation. To determine whether SBTs performed using PSV may hasten extubation without increasing the risk of reintubation as compared to T-piece.","contentPatientsMethods":"Multicenter randomized clinical trial conducted from January 2020 through June 2021 among patients at high-risk of extubation failure, i.e. older than 65 years or with underlying cardiac or respiratory disease, included at 31 ICUs in France. Patients were included before the first SBT and were randomly assigned to one of the 2 following groups performing SBT using PSV (n=484) or using T-piece (n=485). The primary outcome was the number of ventilator-free days at day 28. Secondary outcomes included the number of patients extubated after simple, difficult or prolonged weaning; the number of patients extubated within the 7 days following the first SBT; the number of patients reintubated within the 7 days following extubation; mortality in ICU and up until day 90.","contentResultats":"Among 969 patients who completed the trial, the number of ventilator-free days at day 28 was 27 (IQR 24-27) using PSV and 27 (IQR 23-27) using T-piece (p=0.311). The proportion of patients who passed the first SBT was higher using PSV than using T-piece (79% vs. 72%, p=0.007). The proportion of patients with difficult/prolonged weaning was lower (27% vs. 33%, p=0.015) and the proportion of patients extubated within the first 7 days following the first SBT was higher (98% vs. 94%, p=0.008) using PSV than using T-piece. The rate of reintubation within the 7 days following extubation did not significantly differ between groups (15% using PSV and 13% using T-piece, p=0.510). Mortality did not differ between groups.","contentDiscussion":"","contentConclusion":"In this multicenter randomized controlled trial including 969 patients at high-risk of extubation failure, SBTs performed using PSV did not significantly reduce the number of ventilator-free days at day 28 as compared with T-piece. However, PSV promoted early extubation without increased risk of reintubation.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 2022","published_at":"2022-03-31T12:35:42.000Z","created_by":5,"updated_by":5,"created_at":"2022-03-31T12:30:13.000Z","updated_at":"2022-06-21T15:00:44.000Z","programme":null,"session":null,"infospratique":16,"entities_date_update":null,"databasename":"programme_reanimation-2022","abstract":null,"dateCongress":{"start":"2022-06-22T06:00:00.000Z","end":"2022-06-24T20:00:00.000Z","days":{"0":"2022-06-22T07:00:00.000Z","1":"2022-06-23T07:00:00.000Z","2":"2022-06-24T07:00:00.000Z"},"daysTerms":{"0":"Mercredi 22/06","1":"Jeudi 23/06","2":"Vendredi 24/06"},"interactivityRooms":[{"room":"Amphi bleu","slidoKey":"iuCWfTCjT6S5M2UWHdp22q","color":"congressultralight"},{"room":"Salle Maillot","slidoKey":"ngteNHF4wHKSdG8WewJqVu","color":"congressultralight"},{"room":"Salle 242A","slidoKey":"mdMKezuc8q5TnzhKWkku65","color":"congressultralight"},{"room":"Salle 243","slidoKey":"3e4Rayq59nf1HmKWoekmHD","color":"congressultralight"},{"room":"Salle 253","slidoKey":"xiqGDyiQ8Dr4A8b6XBeLcs","color":"congressultralight"},{"room":"Salle 231/232M","slidoKey":"goQaDNtMPu8Thefqux7t3R","color":"congressultralight"}],"rooms":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"],"actualDate":null},"dataConfig":{"congressName":"SRLF 2022","congressNameWithoutSpace":"SRLF2022","language":"fr","queryText":{"programme":"","programmeTraining":"","abstracts":"","speakers":"","vod":""},"sortedRoom":["Amphithéâtre Bleu","Espace Agora","Salle Maillot"]},"appConfig":{"scanExpoSendMailUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","texts":{"certificateAttendance":"","about":"","schedule":"","vod":"","posters":""},"durationSplashScreen":3000,"splash":false,"loginRequired":false,"splashRedirectionUrl":"","pushNotificationTopicsSize":4,"styleSheetVersion":"1","scanExpoExportUrl":"https://syncdb.europa-group.com/applismartphone/export.php?congres=srlf2022","strapiVersion":"1.4.5","abstractPdf":"","cgu":"https://ressources-smartphone.europa-group.com/2021/GLOBAL/CGU.pdf","socialnetworks":{"youtube":"https://www.youtube.com/channel/UCiIFHXGAoXKXgm4Vn6QDk6Q","facebook":"https://www.facebook.com/medecineintensive/","platform":"","twitter":"https://twitter.com/La_SRLF","website":"https://www.congres-reanimation.fr/","linkedin":"https://www.linkedin.com/company/soci%C3%A9t%C3%A9-de-r%C3%A9animation-de-langue-fran%C3%A7aise-srlf-?trk=company_logo","instagram":"https://www.instagram.com/srlf_officiel/"},"registrationUrl":"https://www.congres-reanimation.fr/inscriptions/inscription","minimalRequiredVersion":{"ios":"1.5.1","android":"1.5.1"},"links":{"certificateAttendance":"","askyourQuestions":"","practicalInfo":"","posters":"","replay":"","neuroQuizz":"","vod":"","practicalInfo2":"","eStand":"","news":"","remotePracticalInformation":""},"privacyPolicy":"https://www.europa-group.com/fr/protection-des-donnees","interactiveMap":{"defaultLevel":0},"notesExportSendMailUrl":"https://syncdb.europa-group.com/applismartphone/exportNotes.php?congres=srlf2022","noShowTabs":["/app/tabs/splash","/app/tabs/chat-list","/app/tabs/new-conversation"],"synopsisPdf":""},"templateConfig":{"slides":[],"mode":"light","buttonTxtColor":"congress","buttonTxtColorButtonCustoms":"congressultralight","buttonBgColor":"light","pictures":[],"logoHeader":"assets/img/logo_congres.png","colorCongress":"#2580c3","logoHeaderBg":"assets/img/logo_congres_bg.jpg"}},"type":"communication orale","exposant":null,"bibliographie":null,"idSession":"886","session":"Session Hot topics","theme":"","motsCles":null,"abstractGuid":null,"contentInfoSupp":"","contentObjectifs":null,"contentObservation":null,"genre":null,"specialite":"Médecin","contentInfoSupp2":"","presentateur":"THILLE Arnaud"},{"id":99612,"num":"A35167JR","reference":"LBA-5","title":"Early Low-Calorie Low-Protein versus Standard-Calorie Standard-Protein Feeding in Ventilated Adults with Shock: A Multicentre, Randomised Trial (NUTRIREA-3)","formatedAuthors":"Jean REIGNIER (1)
(1) CHU de Nantes, Nantes, FRANCE","contentIntroduction":"The optimal calorie and protein supply at the acute phase of severe critical illness remains unknown. Recent data challenge the appropriateness of providing standard amounts of calories and protein during acute critical illness, suggesting beneficial effect of restricting and calorie and protein intake. We hypothesized that early calorie-protein restriction decreased day-90 mortality and/or dependency on ICU management in mechanically ventilated patients receiving vasoactive amine therapy for shock, compared to standard calorie and protein targets.","contentPatientsMethods":"NUTRIREA-3 was a randomized, controlled, multicentre, open-label, parallel-group trial performed in 61 French intensive care units (ICU). Adults receiving invasive mechanical ventilation and vasopressor support for shock were randomised to early calorie-protein restriction (6 kcal/kg/d-0.2-0.4 g/kg/d: Low group) or standard calorie-protein targets (25 kcal/kg/d-1.0-1.3g/kg/d: Standard group) at the acute phase defined as the first 7 days in the ICU. Two primary end-points were evaluated: day-90 mortality and time to ICU discharge readiness. The trial was considered positive if significant between-group differences are found for one or both alternative primary endpoints.","contentResultats":"3044 patients were included. Primary outcomes: By day 28, the cumulative incidence of patients discharge alive from ICU was 61% in the Low group, as compared to 58% in the standard group (hazard ratio [HR], 1.12; 95%CI, 1.02; 1.22; P=0.014). By day 90, 626 (41.2%) of the 1521 patients in the low group and 648 (42.8%) of the 1515 patients in the Standard group had died (Absolute difference, -1.6%; 95%CI, -5.1%; 1.9%; p=0·37). Secondary outcomes: The cumulative incidence of patients with normalisation of blood lactate level from Day-0 to Day-7 was 86.5% in the Low group, as compared to 84.1% in the Standard group (HR, 1.09; 95%CI, 1.02; 1.16; P=0.01). By day 28, the cumulative incidence of patients discharge alive from ICU was 66.6% in the Low group, as compared to 63.2% in the standard group (HR, 1.12; 95%CI, 1.03; 1.22; P=0.007). Proportions of patients with secondary infections did not differ between groups (HR, 0·85; 95%CI, 0·71-1·01; p=0·06). The Low group had lower proportions of patients with vomiting (HR, 0.77; 0.67-0.89; p","contentDiscussion":"","contentConclusion":"As compared to standard calorie-protein targets, calorie-protein restriction was associated with improved outcome in critically ill adults receiving invasive mechanical ventilation and vasopressor support for shock.","published_at":"2022-06-16T16:01:27.000Z","created_by":null,"updated_by":null,"created_at":"2022-06-16T16:01:27.000Z","updated_at":"2022-06-20T15:53:51.000Z","congre":{"id":16,"Nom":"SRLF 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Horaires d'ouverture
Accueil
| Mercredi 22 juin | 07h00 | 19h00 |
| Jeudi 23 juin | 07h30 | 18h45 |
| Vendredi 24 juin | 07h30 | 17h00 |
Vestiaires
| Mercredi 22 juin | 07h00 | 20h15 |
| Jeudi 23 juin | 07h30 | 18h45 |
| Vendredi 24 juin | 07h30 | 17h00 |
Exposition
| Mercredi 22 juin | 07h00 | 19h00 |
| Jeudi 23 juin | 07h30 | 18h45 |
| Vendredi 24 juin | 07h30 | 17h00 |
Pre-projection
| Mercredi 22 juin | 07h30 | 20h00 |
| Jeudi 23 juin | 07h30 | 18h45 |
| Vendredi 24 juin | 07h30 | 17h00 |
Wifi
Réseau : SRLF - Réanimation 2022
Pas de mot de passe nécessaire.
Salle de Soins
La SRLF met à votre disposition une salle pour vos soins : 236M.
Cette salle se trouve au-dessus de l'Amphithéâtre Bleu et est accessible par escalier ou ascenseur.
Attestations de présence
Les attestations de présence seront envoyées par email dans les 10 jours suivants la fin de l'évènement. Si vous souhaitez modifier votre adresse mail, nous vous invitons à vous rendre à l'accueil du congrès (niveau 0).
Dîner du Congrès
La SRLF vous invite à participer à un cocktail privé au Musée Carnavalet.
La participation à cette soirée se fait sur inscription et est payante (80,00€ TTC). Rendez-vous à l’accueil du congrès (niveau 0) pour vérifier s’il reste de la place !
Lieu
Palais de Congrès de Paris
2, place de la Porte Maillot, 75017 Paris
Site Internet : www.palaisdescongres-paris.com
L'accueil du congrès se situe au niveau 0. L'exposition et les salles de conférences sont au niveau 2, accès par l'escalator côté Neuilly.
Accès par les transports en commun
![\"métro\"](\"https://www.congres-reanimation.fr/sites/default/files/inline-images/logo_metro.png\"){kind=logo}
Plan du métroLigne 1
Station
Porte Maillot-Palais des Congrès
![\"métro\"](\"https://www.congres-reanimation.fr/sites/default/files/inline-images/logo_rer.png\"){kind=logo}
Plan du RERRER C
Station
Neuilly Porte Maillot – Palais des Congrès
![\"métro\"](\"https://www.congres-reanimation.fr/sites/default/files/inline-images/logo_bus.png\"){kind=logo}
Plan des busLignes 43, 73, 82, 244, PC1, PC2, PC3
Arrêt
Porte Maillot
Réserver un taxi
Taxis G7 : 3607 ou 01.47.39.47.39
Taxis Bleus : 0.891.70.10.10 ou 01.49.36.29.48
La Société de Réanimation de Langue Française (SRLF) est une société savante fondée en 1971. Elle regroupe aujourd’hui 3800 membres et mène des activités variées qui tournent autour de deux axes principaux :
- la formation continue et l’enseignement post-universitaire,
- la promotion de la recherche clinique et l’évaluation de l’activité de réanimation à l’hôpital.
A travers ces deux axes, la SRLF et, avec elle, l’ensemble du monde de la réanimation, poursuit un objectif fondamental : donner à la réanimation sa juste place dans le système sanitaire.
Pour fonctionner et agir efficacement, la SRLF s’appuie sur un Conseil d’Administration de 11 membres médecins et d’un membre paramédical, et sur 11 commissions de travail (Commission du Congrès Médical, Commission des Référentiels et de l’Evaluation, Commission d’Ethique, Commission de Recherche Translationnelle, Comité de Rédaction de la revue Médecine Intensive Réanimation, Comité de Coordination et d’Organisation des Formations, Commission de Médecine des Urgences Vitales, Commission d’Epidémiologie et de Recherche Clinique, Commission Jeunes, Commission des Publications Electroniques et Commission du Congrès Infirmier).
https://www.srlf.org/","replay":"Conseil d’Administration
Composition du Bureau :
PRÉSIDENT
Pr Eric MAURY (Paris)
PRÉSIDENT DÉSIGNÉ
Pr Laurent PAPAZIAN, Bastia
VICE-PRÉSIDENT
Pr Fekri ABROUG, Monastir
VICE-PRÉSIDENTE PARAMÉDICALE
Mme Sylvie L’HOTELLIER, Strasbourg
SECRÉTAIRE GÉNÉRAL
Pr Michael DARMON, Paris
SECRÉTAIRE GÉNÉRAL ADJOINT
Pr Alexandre DEMOULE, Paris
TRÉSORIÈRE
Dr Florence BOISSIER, Poitiers
RESPONSABLE DES PRIX ET BOURSES
Pr Nicolas TERZI, Grenoble
Membres :
- Mme Anne-Sophie DEBU (Paris)
- Dr Jan HAYON (Poissy) – Représentant du GFRUP
- Dr Edouard OBADIA (Quincy-sous-Sénart) - Représentant du l’ARDSP
- Mme Aurélia PAPIN (Angers) - Représentante de la FNIR
- Dr Jean-Philippe RIGAUD (Dieppe)
- Dr Frédérique SCHORTGEN (Créteil)
- Pr Guillaume THIERY (Saint-Etienne)
Commission du Congrès Médical
La Commission du Congrès Médical de la SRLF est en charge de l’organisation scientifique du congrès « Réanimation », qui a lieu chaque année.
Secrétaire :
- Pr Frédéric PÈNE (Paris)
Membres :
- Dr Laetitia BODET-CONTENTIN (Tours)
- Pr Emmanuel CANET (Nantes)
- Pr Guillaume CARTEAUX (Créteil)
- Dr Jean-Pierre FRAT (Poitiers)
- Pr Guillaume GERI (Boulogne-Billancourt)
- Dr Olfa HAMZAOUI (Clamart)
- Pr Julie HELMS (Strasbourg)
- Pr Mathieu JOZWIAK (Nice)
- Pr Saad NSEIR (Lille)
- Pr Nicolas WEISS (Paris)
- Pr Michael DARMON (Paris) – Représentant du CA
- Dr Mathilde LERMUZEAUX (Saint-Denis) – Représentante de la CUV
- Dr Mehdi OUALHA (Paris) – Représentant du GFRUP
Commission du Congrès Infirmier
La Commission du Congrès Infirmier est chargée du programme scientifique de la partie infirmière du congrès annuel de la SRLF.
Secrétaire :
- Mme Sandrine MONOT (Paris)
Membres :
- Dr François BARBIER (Orléans)
- Mme Maud GUTH (Paris)
- Mme Marie LECRONIER (Créteil)
- Mme Anne-Sophie LEQUEULX (Paris)
- Mme Estelle MANTIN (Vichy)
- Mme Aurélia PAPIN (Angers)
- Mr Maxime PERRODET (Marseille)
- Mme Nadine ROBQUIN (Villeneuve-Saint-Georges)
- Mr Damien SCOUVART (Strasbourg)
- Mme Virginie SOUPPART (Paris)
- Mme Christine FAYEULLE (Lille) - Représentante du GFRUP
- Mme Sylvie L’HOTELLIER (Strasbourg) - Représentante du CA
- Dr Raphaël MINJARD (Lyon) - Invité de Commission
- Mr Mathieu REFFIENNA (Paris) - Représentant de la SKR